Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M)

Chemical Research in Toxicology

Volumn 24, Issue 4, 2011, Pages 568-578

  Nassar, A E F ^a   King, I ^b   Du, J ^b  

^a BRANDEIS UNIVERSITY   (United States)

^b Vion Pharmaceuticals Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CYSTEINE; GLUTATHIONE; LAROMUSTINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG METABOLISM; HUMAN; HUMAN TISSUE; LIVER MICROSOME METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACETYLCYSTEINE; ANTINEOPLASTIC AGENTS; CARBON ISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; GLUTATHIONE; HUMANS; HYDRAZINES; MAGNETIC RESONANCE SPECTROSCOPY; MICROSOMES, LIVER; NADP; NEOPLASMS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONAMIDES;

EID: 79954455165     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx100453t     Document Type: Article

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