Strategies for dealing with metabolite elucidation in drug discovery and development

Drug Discovery Today

Volumn 9, Issue 7, 2004, Pages 317-327

  Nassar, Alaa Eldin F ^a   Talaat, Rasmy E ^a  

^a PFIZER INC   (United States)

Author keywords

Chemical Biology; Drug Discovery; Exact mass analysis; Hydrogen deuterium exchange method; In silico; Liquid chromatography mass spectrometry; Metabolite identification; Pharmaceutical Science; Techniques Methods

Indexed keywords

DEXTROMETHORPHAN; DRUG METABOLITE; NIMODIPINE;

ANALYTIC METHOD; COMPUTER MODEL; COMPUTER PROGRAM; DRUG SCREENING; DRUG STRUCTURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; ONLINE ANALYSIS; REVIEW;

ANIMALS; BIOTRANSFORMATION; CLINICAL TRIALS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HUMANS; PHARMACEUTICAL PREPARATIONS; PHARMACOLOGY, CLINICAL;

EID: 1642368205     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(03)03018-6     Document Type: Review

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