The localization and concentration of the PDE2-encoded high-affinity cAMP phosphodiesterase is regulated by cAMP-dependent protein kinase A in the yeast Saccharomyces cerevisiae

FEMS Yeast Research

Volumn 10, Issue 2, 2010, Pages 177-187

  Hu, Yun ^a   Liu, Enkai ^a   Bai, Xiaojia ^a   Zhang, Aili ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

Cyclic AMP; High affinity cAMP phosphodiesterase; Nuclear localization; Pde2; Protein kinase A; Saccharomyces cerevisiae

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP PHOSPHODIESTERASE; GLUCOSE; PHOSPHODIESTERASE; PHOSPHODIESTERASE 2; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL LEVEL; CELL NUCLEUS; CONCENTRATION (PARAMETERS); CYTOPLASM; ENZYME LOCALIZATION; FUNGAL STRAIN; FUNGUS GROWTH; NEGATIVE FEEDBACK; NONHUMAN; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE; WILD TYPE; YEAST;

CELL NUCLEUS; CULTURE MEDIA; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 2; GENE EXPRESSION REGULATION, FUNGAL; MICROSCOPY, FLUORESCENCE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 76349105919     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2009.00598.x     Document Type: Article

References (46)

1. Balciunas D Ronne H (1999) Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells. Mol Gen Genet 262 : 589 599.
2. Beavo JA Brunton LL (2002) Cyclic nucleotide research - still expanding after half a century. Nat Rev Mol Cell Bio 3 : 710 718.
3. Beebe SJ (1994) The cAMP-dependent protein kinases and cAMP signal transduction. Semin Cancer Biol 5 : 285 294.
4. Beene DL Scott JD (2007) A-kinase anchoring proteins take shape. Curr Opin Cell Biol 19 : 192 198.
5. Broek D, Samiy N, Fasano O, Fujiyama A, Tamanoi F, Northup J Wigler M (1985) Differential activation of yeast adenylate cyclase by wild-type and mutant RAS proteins. Cell 41 : 763 769.
6. Charbonneau H, Beier N, Walsh KA Beavo JA (1986) Identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species. P Natl Acad Sci USA 83 : 9308 9312.
7. Dan Burke DD Tim Stearns (2000) Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
8. De Vendittis E, Vitelli A, Zahn R Fasano O (1986) Suppression of defective RAS1 and RAS2 functions in yeast by an adenylate cyclase activated by a single amino acid change. EMBO J 5 : 3657 3663.
9. Dodge KL, Khouangsathiene S, Kapiloff MS, Mouton R, Hill EV, Houslay MD, Langeberg LK Scott JD (2001) mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J 20 : 1921 1930.
10. Georget M, Mateo P, Vandecasteele G, Lipskaia L, Defer N, Hanoune J, Hoerter J, Lugnier C Fischmeister R (2003) Cyclic AMP compartmentation due to increased cAMP-phosphodiesterase activity in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8). FASEB J 17 : 1380 1391.
11. Gietz RD Sugino A (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74 : 527 534.
12. Griffioen G, Anghileri P, Imre E, Baroni MD Ruis H (2000) Nutritional control of nucleocytoplasmic localization of cAMP-dependent protein kinase catalytic and regulatory subunits in Saccharomyces cerevisiae. J Biol Chem 275 : 1449 1456.
13. Griffioen G, Branduardi P, Ballarini A, Anghileri P, Norbeck J, Baroni MD Ruis H (2001) Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domain. Mol Cell Biol 21 : 511 523.
14. Houslay MD (2001) PDE4 cAMP-specific phosphodiesterases. Prog Nucleic Acid Re 69 : 249 315.
15. Houslay MD Adams DR (2003) PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. Biochem J 370 : 1 18.
16. Hubbard EJ, Yang XL Carlson M (1992) Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae. Genetics 130 : 71 80.
17. Langeberg LK Scott JD (2005) A-kinase-anchoring proteins. J Cell Sci 118 : 3217 3220.
18. Londesborough J (1977) Characterization of an adenosine 3′:5′-cyclic monophosphate phosphodiesterase from baker's yeast. Its binding to subcellular particles, catalytic properties and gel-filtration behaviour. Biochem J 163 : 467 476.
19. Londesborough J Lukkari TM (1980) The pH and temperature dependence of the activity of the high Km cyclic nucleotide phosphodiesterase of bakers' yeast. J Biol Chem 255 : 9262 9267.
20. Ma P, Wera S, Van Dijck P Thevelein JM (1999) The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling. Mol Biol Cell 10 : 91 104.
21. Mitsuzawa H (1993) Responsiveness to exogenous cAMP of a Saccharomyces cerevisiae strain conferred by naturally occurring alleles of PDE1 and PDE2. Genetics 135 : 321 326.
22. Munder T Kuntzel H (1989) Glucose-induced cAMP signaling in Saccharomyces cerevisiae is mediated by the CDC25 protein. FEBS Lett 242 : 341 345.
23. Nikawa J, Cameron S, Toda T, Ferguson KM Wigler M (1987a) Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae. Gene Dev 1 : 931 937.
24. Nikawa J, Sass P Wigler M (1987b) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7 : 3629 3636.
25. Pache JC, Burton DW, Deftos LJ Hastings RH (2006) A carboxyl leucine-rich region of parathyroid hormone-related protein is critical for nuclear export. Endocrinology 147 : 990 998.
26. Park JI, Grant CM Dawes IW (2005) The high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae is the major determinant of cAMP levels in stationary phase: involvement of different branches of the Ras-cyclic AMP pathway in stress responses. Biochem Bioph Res Co 327 : 311 319.
27. Persani L, Lania A, Alberti L, Romoli R, Mantovani G, Filetti S, Spada A Conti M (2000) Induction of specific phosphodiesterase isoforms by constitutive activation of the cAMP pathway in autonomous thyroid adenomas. J Clin Endocr Metab 85 : 2872 2878.
28. Persani L, Borgato S, Lania A, Filopanti M, Mantovani G, Conti M Spada A (2001) Relevant cAMP-specific phosphodiesterase isoforms in human pituitary: effect of Gs(alpha) mutations. J Clin Endocr Metab 86 : 3795 3800.
29. Poplinski A, Hopp C Ramezani-Rad M (2007) Ste50 adaptor protein influences Ras/cAMP-driven stress-response and cell survival in Saccharomyces cerevisiae. Curr Genet 51 : 257 268.
30. Resnick RJ Racker E (1988) Phosphorylation of the RAS2 gene product by protein kinase A inhibits the activation of yeast adenylyl cyclase. P Natl Acad Sci USA 85 : 2474 2478.
31. Roosen J, Engelen K, Marchal K, Mathys J, Griffioen G, Cameroni E, Thevelein JM, De Virgilio C, De Moor B Winderickx J (2005) PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability. Mol Microbiol 55 : 862 880.
32. Sass P, Field J, Nikawa J, Toda T Wigler M (1986) Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae. P Natl Acad Sci USA 83 : 9303 9307.
33. Smith FD Scott JD (2006) Anchored cAMP signaling: onward and upward - a short history of compartmentalized cAMP signal transduction. Eur J Cell Biol 85 : 585 592.
34. 2+-dependent, low Km cyclic AMP phosphodiesterase from bakers' yeast. J Biol Chem 259 : 6964 6971.
35. Tanaka K, Matsumoto K Toh EA (1989) IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae. Mol Cell Biol 9 : 757 768. (Pubitemid 19038876)
36. Tanaka K, Nakafuku M, Satoh T, Marshall MS, Gibbs JB, Matsumoto K, Kaziro Y Toh-e A (1990) S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein. Cell 60 : 803 807.
37. Tanaka K, Wood DR, Lin BK, Khalil M, Tamanoi F Cannon JF (1992) A dominant activating mutation in the effector region of RAS abolishes IRA2 sensitivity. Mol Cell Biol 12 : 631 637.
38. Tasken KA, Collas P, Kemmner WA, Witczak O, Conti M Tasken K (2001) Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area. J Biol Chem 276 : 21999 22002.
39. Thevelein JM (1992) The RAS-adenylate cyclase pathway and cell cycle control in Saccharomyces cerevisiae. Antonie van Leeuwenhoek 62 : 109 130.
40. Thevelein JM de Winde JH (1999) Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33 : 904 918.
41. Thevelein JM, Beullens M, Honshoven F, Hoebeeck G, Detremerie K, Griewel B, den Hollander JA Jans AW (1987) Regulation of the cAMP level in the yeast Saccharomyces cerevisiae: the glucose-induced cAMP signal is not mediated by a transient drop in the intracellular pH. J Gen Microbiol 133 : 2197 2205.
42. Thomas BJ Rothstein R (1989) Elevated recombination rates in transcriptionally active DNA. Cell 56 : 619 630.
43. Toda T, Uno I, Ishikawa T, Powers S, Kataoka T, Broek D, Cameron S, Broach J, Matsumoto K Wigler M (1985) In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell 40 : 27 36.
44. Wang S, Xie W, Rylander MN, Tucker PW, Aggarwal S Diller KR (2008) HSP70 kinetics study by continuous observation of HSP-GFP fusion protein expression on a perfusion heating stage. Biotechnol Bioeng 99 : 146 154.
45. Wilson RB, Renault G, Jacquet M Tatchell K (1993) The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracellular cAMP. FEBS Lett 325 : 191 195.
46. Wong W Scott JD (2004) AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Bio 5 : 959 970.