-
1
-
-
50249154326
-
DUBs and disease: Activity assays for inhibitor development
-
A. Shanmugham, and H. Ovaa DUBs and disease: activity assays for inhibitor development Curr. Opin. Drug Discov. Dev. 11 2008 688 696
-
(2008)
Curr. Opin. Drug Discov. Dev.
, vol.11
, pp. 688-696
-
-
Shanmugham, A.1
Ovaa, H.2
-
2
-
-
54249106271
-
Deubiquitylating enzymes and disease
-
S. Singhal, M.C. Taylor, and R.T. Baker Deubiquitylating enzymes and disease BMC Biochem. 9 Suppl. 1 2008 S3
-
(2008)
BMC Biochem.
, vol.9
, Issue.SUPPL. 1
, pp. 3
-
-
Singhal, S.1
Taylor, M.C.2
Baker, R.T.3
-
3
-
-
74849133896
-
Proteasome system of protein degradation and processing
-
A.V. Sorokin, E.R. Kim, and L.P. Ovchinnikov Proteasome system of protein degradation and processing Biochemistry 74 2009 1411 1442
-
(2009)
Biochemistry
, vol.74
, pp. 1411-1442
-
-
Sorokin, A.V.1
Kim, E.R.2
Ovchinnikov, L.P.3
-
4
-
-
63649116570
-
Ubiquitylation in innate and adaptive immunity
-
V.G. Bhoj, and Z.J. Chen Ubiquitylation in innate and adaptive immunity Nature 458 2009 430 437
-
(2009)
Nature
, vol.458
, pp. 430-437
-
-
Bhoj, V.G.1
Chen, Z.J.2
-
5
-
-
69649103904
-
DUBs at a glance
-
K.D. Wilkinson DUBs at a glance J. Cell Sci. 122 2009 2325 2329
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2325-2329
-
-
Wilkinson, K.D.1
-
6
-
-
0035444169
-
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia
-
L.J. Kurihara, T. Kikuchi, K. Wada, and S.M. Tilghman Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia Hum. Mol. Genet. 10 2001 1963 1970 (Pubitemid 32910541)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.18
, pp. 1963-1970
-
-
Kurihara, L.J.1
Kikuchi, T.2
Wada, K.3
Tilghman, S.M.4
-
7
-
-
43049124129
-
Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice
-
DOI 10.1172/JCI34257
-
W. Jin, M. Chang, E.M. Paul, G. Babu, A.J. Lee, W. Reiley, A. Wright, M. Zhang, J. You, and S.C. Sun Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice J. Clin. Invest. 118 2008 1858 1866 (Pubitemid 351632388)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.5
, pp. 1858-1866
-
-
Jin, W.1
Chang, M.2
Paul, E.M.3
Babu, G.4
Lee, A.J.5
Reiley, W.6
Wright, A.7
Zhang, M.8
You, J.9
Sun, S.-C.10
-
8
-
-
54249104026
-
The ubiquitin system, disease, and drug discovery
-
M.D. Petroski The ubiquitin system, disease, and drug discovery BMC Biochem. 9 Suppl. 1 2008 S7
-
(2008)
BMC Biochem.
, vol.9
, Issue.SUPPL. 1
, pp. 7
-
-
Petroski, M.D.1
-
9
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
DOI 10.1016/j.cell.2005.11.007, PII S0092867405011694
-
S.M. Nijman, M.P. Luna-Vargas, A. Velds, T.R. Brummelkamp, A.M. Dirac, T.K. Sixma, and R. Bernards A genomic and functional inventory of deubiquitinating enzymes Cell 123 2005 773 786 (Pubitemid 41721026)
-
(2005)
Cell
, vol.123
, Issue.5
, pp. 773-786
-
-
Nijman, S.M.B.1
Luna-Vargas, M.P.A.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.G.5
Sixma, T.K.6
Bernards, R.7
-
10
-
-
0034117284
-
Expression and functional analysis of Uch-L3 during mouse development
-
DOI 10.1128/MCB.20.7.2498-2504.2000
-
L.J. Kurihara, E. Semenova, J.M. Levorse, and S.M. Tilghman Expression and functional analysis of Uch-L3 during mouse development Mol. Cell. Biol. 20 2000 2498 2504 (Pubitemid 30152057)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.7
, pp. 2498-2504
-
-
Kurihara, L.J.1
Semenova, E.2
Levorse, J.M.3
Tilghman, S.M.4
-
11
-
-
67349087271
-
Cell responses to bone morphogenetic proteins and peptides derived from them: Biomedical applications and limitations
-
H. Senta, H. Park, E. Bergeron, O. Drevelle, D. Fong, E. Leblanc, F. Cabana, S. Roux, G. Grenier, and N. Faucheux Cell responses to bone morphogenetic proteins and peptides derived from them: biomedical applications and limitations Cytokine Growth Factor Rev. 20 2009 213 222
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 213-222
-
-
Senta, H.1
Park, H.2
Bergeron, E.3
Drevelle, O.4
Fong, D.5
Leblanc, E.6
Cabana, F.7
Roux, S.8
Grenier, G.9
Faucheux, N.10
-
12
-
-
58149093172
-
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
-
S. Dupont, A. Mamidi, M. Cordenonsi, M. Montagner, L. Zacchigna, M. Adorno, G. Martello, M.J. Stinchfield, S. Soligo, L. Morsut, M. Inui, S. Moro, N. Modena, F. Argenton, S.J. Newfeld, and S. Piccolo FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination Cell 136 2009 123 135
-
(2009)
Cell
, vol.136
, pp. 123-135
-
-
Dupont, S.1
Mamidi, A.2
Cordenonsi, M.3
Montagner, M.4
Zacchigna, L.5
Adorno, M.6
Martello, G.7
Stinchfield, M.J.8
Soligo, S.9
Morsut, L.10
Inui, M.11
Moro, S.12
Modena, N.13
Argenton, F.14
Newfeld, S.J.15
Piccolo, S.16
-
13
-
-
27944498719
-
The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-β signalling
-
DOI 10.1038/sj.onc.1208944
-
S.J. Wicks, K. Haros, M. Maillard, L. Song, R.E. Cohen, P.T. Dijke, and A. Chantry The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling Oncogene 24 2005 8080 8084 (Pubitemid 41746751)
-
(2005)
Oncogene
, vol.24
, Issue.54
, pp. 8080-8084
-
-
Wicks, S.J.1
Haros, K.2
Maillard, M.3
Song, L.4
Cohen, R.E.5
Ten Dijke, P.6
Chantry, A.7
-
14
-
-
67650146161
-
Positive reciprocal regulation of ubiquitin C-terminal hydrolase L1 and beta-catenin/TCF signaling
-
A. Bheda, W. Yue, A. Gullapalli, C. Whitehurst, R. Liu, J.S. Pagano, and J. Shackelford Positive reciprocal regulation of ubiquitin C-terminal hydrolase L1 and beta-catenin/TCF signaling PLoS ONE 4 2009 e5955
-
(2009)
PLoS ONE
, vol.4
, pp. 5955
-
-
Bheda, A.1
Yue, W.2
Gullapalli, A.3
Whitehurst, C.4
Liu, R.5
Pagano, J.S.6
Shackelford, J.7
-
15
-
-
17044378584
-
Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling
-
M. Datto, and X.F. Wang Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling Cell 121 2005 2 4
-
(2005)
Cell
, vol.121
, pp. 2-4
-
-
Datto, M.1
Wang, X.F.2
-
16
-
-
24044547036
-
Regulating the regulators: Control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli
-
DOI 10.1016/j.molcel.2005.08.017, PII S1097276505015595
-
M. Gao, and M. Karin Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli Mol. Cell 19 2005 581 593 (Pubitemid 41219435)
-
(2005)
Molecular Cell
, vol.19
, Issue.5
, pp. 581-593
-
-
Gao, M.1
Karin, M.2
-
17
-
-
33751277951
-
Reversible ubiquitination regulates the Smad/TGF-β signalling pathway
-
DOI 10.1042/BST0340761
-
S.J. Wicks, T. Grocott, K. Haros, M. Maillard, P. Ten Dijke, and A. Chantry Reversible ubiquitination regulates the Smad/TGF-beta signalling pathway Biochem. Soc. Trans. 34 2006 761 763 (Pubitemid 44796415)
-
(2006)
Biochemical Society Transactions
, vol.34
, Issue.5
, pp. 761-763
-
-
Wicks, S.J.1
Grocott, T.2
Haros, K.3
Maillard, M.4
Ten Dijke, P.5
Chantry, A.6
-
18
-
-
33745728745
-
Photoreceptor cell apoptosis in the retinal degeneration of Uchl3-deficient mice
-
Y. Sano, A. Furuta, R. Setsuie, H. Kikuchi, Y.L. Wang, M. Sakurai, J. Kwon, M. Noda, and K. Wada Photoreceptor cell apoptosis in the retinal degeneration of Uchl3-deficient mice Am. J. Pathol. 169 2006 132 141
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 132-141
-
-
Sano, Y.1
Furuta, A.2
Setsuie, R.3
Kikuchi, H.4
Wang, Y.L.5
Sakurai, M.6
Kwon, J.7
Noda, M.8
Wada, K.9
-
19
-
-
0038683341
-
An engineered 800 kilobase deletion of Uchl3 and Lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina
-
DOI 10.1093/hmg/ddg140
-
E. Semenova, X. Wang, M.M. Jablonski, J. Levorse, and S.M. Tilghman An engineered 800 kilobase deletion of Uchl3 and Lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina Hum. Mol. Genet. 12 2003 1301 1312 (Pubitemid 36722610)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.11
, pp. 1301-1312
-
-
Semenova, E.1
Wang, X.2
Jablonski, M.M.3
Levorse, J.4
Tilghman, S.M.5
-
20
-
-
34248231741
-
The new function of two ubiquitin C-terminal hydrolase isozymes as reciprocal modulators of germ cell apoptosis
-
DOI 10.1538/expanim.56.71
-
J. Kwon The new function of two ubiquitin C-terminal hydrolase isozymes as reciprocal modulators of germ cell apoptosis Exp. Anim. 56 2007 71 77 (Pubitemid 46711790)
-
(2007)
Experimental Animals
, vol.56
, Issue.2
, pp. 71-77
-
-
Kwon, J.1
-
21
-
-
72749112595
-
Ubiquitin C-terminal hydrolase-L3-knockout mice are resistant to diet-induced obesity and show increased activation of AMP-activated protein kinase in skeletal muscle
-
R. Setsuie, M. Suzuki, T. Kabuta, H. Fujita, S. Miura, N. Ichihara, D. Yamada, Y.L. Wang, O. Ezaki, Y. Suzuki, and K. Wada Ubiquitin C-terminal hydrolase-L3-knockout mice are resistant to diet-induced obesity and show increased activation of AMP-activated protein kinase in skeletal muscle FASEB J. 23 12 2009 4148 4157
-
(2009)
FASEB J.
, vol.23
, Issue.12
, pp. 4148-4157
-
-
Setsuie, R.1
Suzuki, M.2
Kabuta, T.3
Fujita, H.4
Miura, S.5
Ichihara, N.6
Yamada, D.7
Wang, Y.L.8
Ezaki, O.9
Suzuki, Y.10
Wada, K.11
-
22
-
-
71949103907
-
Ubiquitin carboxyl-terminal hydrolase l3 promotes insulin signaling and adipogenesis
-
M. Suzuki, R. Setsuie, and K. Wada Ubiquitin carboxyl-terminal hydrolase l3 promotes insulin signaling and adipogenesis Endocrinology 150 2009 5230 5239
-
(2009)
Endocrinology
, vol.150
, pp. 5230-5239
-
-
Suzuki, M.1
Setsuie, R.2
Wada, K.3
-
23
-
-
77952878619
-
Skeletal muscles of Uchl3 knockout mice show polyubiquitinated protein accumulation and stress responses
-
R. Setsuie, M. Suzuki, Y. Tsuchiya, and K. Wada Skeletal muscles of Uchl3 knockout mice show polyubiquitinated protein accumulation and stress responses Neurochem. Int. 56 2010 911 918
-
(2010)
Neurochem. Int.
, vol.56
, pp. 911-918
-
-
Setsuie, R.1
Suzuki, M.2
Tsuchiya, Y.3
Wada, K.4
-
24
-
-
77953694906
-
The potential role of ubiquitin c-terminal hydrolases in oncogenesis
-
Y. Fang, D. Fu, and X.Z. Shen The potential role of ubiquitin c-terminal hydrolases in oncogenesis Biochim. Biophys. Acta 1806 2010 1 6
-
(2010)
Biochim. Biophys. Acta
, vol.1806
, pp. 1-6
-
-
Fang, Y.1
Fu, D.2
Shen, X.Z.3
-
25
-
-
33744510119
-
High expression of ubiquitin caboxy-terminal hydrolase-L1 and -L3 mRNA predicts early recurrence in patients with invasive breast cancer
-
DOI 10.1111/j.1349-7006.2006.00202.x
-
Y. Miyoshi, S. Nakayama, Y. Torikoshi, S. Tanaka, H. Ishihara, T. Taguchi, Y. Tamaki, and S. Noguchi High expression of ubiquitin carboxy-terminal hydrolase-L1 and -L3 mRNA predicts early recurrence in patients with invasive breast cancer Cancer Sci. 97 2006 523 529 (Pubitemid 43811594)
-
(2006)
Cancer Science
, vol.97
, Issue.6
, pp. 523-529
-
-
Miyoshi, Y.1
Nakayama, S.2
Torikoshi, Y.3
Tanaka, S.4
Ishihara, H.5
Taguchi, T.6
Tamaki, Y.7
Noguchi, S.8
-
26
-
-
33645449857
-
Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines
-
U. Rolen, V. Kobzeva, N. Gasparjan, H. Ovaa, G. Winberg, F. Kisseljov, and M.G. Masucci Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines Mol. Carcinog. 45 2006 260 269
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 260-269
-
-
Rolen, U.1
Kobzeva, V.2
Gasparjan, N.3
Ovaa, H.4
Winberg, G.5
Kisseljov, F.6
Masucci, M.G.7
-
27
-
-
70349977110
-
'Two-stage double-technique hybrid (TSDTH)' identification strategy for the analysis of BMP2-induced transdifferentiation of premyoblast C2C12 cells to osteoblast
-
B.G. Kim, J.H. Lee, J.M. Ahn, S.K. Park, J.H. Cho, D. Hwang, J.S. Yoo, J.R. Yates III, H.M. Ryoo, and J.Y. Cho 'Two-stage double-technique hybrid (TSDTH)' identification strategy for the analysis of BMP2-induced transdifferentiation of premyoblast C2C12 cells to osteoblast J. Proteome Res. 8 2009 4441 4454
-
(2009)
J. Proteome Res.
, vol.8
, pp. 4441-4454
-
-
Kim, B.G.1
Lee, J.H.2
Ahn, J.M.3
Park, S.K.4
Cho, J.H.5
Hwang, D.6
Yoo, J.S.7
Iii, R.Y.J.8
Ryoo, H.M.9
Cho, J.Y.10
-
28
-
-
0031050550
-
Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display
-
DOI 10.1002/(SICI)1097-4644(199701)64:1<106::AID-JCB13>3.0.CO;2-J
-
H.M. Ryoo, A.J. van Wijnen, J.L. Stein, J.B. Lian, and G.S. Stein Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display J. Cell. Biochem. 64 1997 106 116 (Pubitemid 27082322)
-
(1997)
Journal of Cellular Biochemistry
, vol.64
, Issue.1
, pp. 106-116
-
-
Ryoo, H.-M.1
Van Wijnen, A.J.2
Stein, J.L.3
Lian, J.B.4
Stein, G.S.5
-
29
-
-
0037414760
-
The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2
-
H.J. Kim, J.H. Kim, S.C. Bae, J.Y. Choi, H.J. Kim, and H.M. Ryoo The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2 J. Biol. Chem. 278 2003 319 326
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 319-326
-
-
Kim, H.J.1
Kim, J.H.2
Bae, S.C.3
Choi, J.Y.4
Kim, H.J.5
Ryoo, H.M.6
-
30
-
-
0038049138
-
Osteoblast isolation from murine calvariae and long bones
-
A. Bakker, and J. Klein-Nulend Osteoblast isolation from murine calvariae and long bones Methods Mol. Med. 80 2003 19 28
-
(2003)
Methods Mol. Med.
, vol.80
, pp. 19-28
-
-
Bakker, A.1
Klein-Nulend, J.2
-
31
-
-
50949111817
-
Osteolineage niche cells initiate hematopoietic stem cell mobilization
-
S.R. Mayack, and A.J. Wagers Osteolineage niche cells initiate hematopoietic stem cell mobilization Blood 112 2008 519 531
-
(2008)
Blood
, vol.112
, pp. 519-531
-
-
Mayack, S.R.1
Wagers, A.J.2
-
32
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
M.E. Sowa, E.J. Bennett, S.P. Gygi, and J.W. Harper Defining the human deubiquitinating enzyme interaction landscape Cell 138 2009 389 403
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
33
-
-
0029931509
-
A human Mad protein acting as a BMP-regulated transcriptional activator
-
DOI 10.1038/381620a0
-
F. Liu, A. Hata, J.C. Baker, J. Doody, R.M. Harland, and J. Massague A human mad protein acting as a BMP-regulated transcriptional activator Nature 381 1996 620 623 (Pubitemid 26177480)
-
(1996)
Nature
, vol.381
, Issue.6583
, pp. 620-623
-
-
Liu, F.1
Hata, A.2
Baker, J.C.3
Doody, J.4
Carcamo, J.5
Harland, R.M.6
Massague, J.7
-
34
-
-
65549151598
-
FGF2 stimulates SDF-1 expression through the Erm transcription factor in Sertoli cells
-
K.A. Yoon, Y.M. Chae, and J.Y. Cho FGF2 stimulates SDF-1 expression through the Erm transcription factor in Sertoli cells J. Cell. Physiol. 220 2009 245 256
-
(2009)
J. Cell. Physiol.
, vol.220
, pp. 245-256
-
-
Yoon, K.A.1
Chae, Y.M.2
Cho, J.Y.3
-
35
-
-
77954216551
-
Expression profiling of ETS and MMP factors in VEGF-activated endothelial cells: Role of MMP-10 in VEGF-induced angiogenesis
-
S.H. Heo, Y.J. Choi, H.M. Ryoo, and J.Y. Cho Expression profiling of ETS and MMP factors in VEGF-activated endothelial cells: role of MMP-10 in VEGF-induced angiogenesis J. Cell. Physiol. 224 2010 734 742
-
(2010)
J. Cell. Physiol.
, vol.224
, pp. 734-742
-
-
Heo, S.H.1
Choi, Y.J.2
Ryoo, H.M.3
Cho, J.Y.4
-
36
-
-
61449168881
-
The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity
-
J.Y. Kim, and K. Ozato The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity J. Immunol. 182 2009 2131 2140
-
(2009)
J. Immunol.
, vol.182
, pp. 2131-2140
-
-
Kim, J.Y.1
Ozato, K.2
-
37
-
-
33847648883
-
The suppressive effect of myeloid Elf-1-like factor (MEF) in osteogenic differentiation
-
Y.J. Kim, B.G. Kim, S.J. Lee, H.K. Lee, S.H. Lee, H.M. Ryoo, and J.Y. Cho The suppressive effect of myeloid Elf-1-like factor (MEF) in osteogenic differentiation J. Cell. Physiol. 211 2007 253 260
-
(2007)
J. Cell. Physiol.
, vol.211
, pp. 253-260
-
-
Kim, Y.J.1
Kim, B.G.2
Lee, S.J.3
Lee, H.K.4
Lee, S.H.5
Ryoo, H.M.6
Cho, J.Y.7
-
38
-
-
0032578855
-
Cleavage of the C-terminus of NEDD8 by UCH-L3
-
DOI 10.1006/bbrc.1998.9532
-
H. Wada, K. Kito, L.S. Caskey, E.T. Yeh, and T. Kamitani Cleavage of the C-terminus of NEDD8 by UCH-L3 Biochem. Biophys. Res. Commun. 251 1998 688 692 (Pubitemid 28512771)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.251
, Issue.3
, pp. 688-692
-
-
Wada, H.1
Kito, K.2
Caskey, L.S.3
Yeh, E.T.H.4
Kamitani, T.5
-
39
-
-
38049177658
-
The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel
-
M.B. Butterworth, R.S. Edinger, H. Ovaa, D. Burg, J.P. Johnson, and R.A. Frizzell The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel J. Biol. Chem. 282 2007 37885 37893
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 37885-37893
-
-
Butterworth, M.B.1
Edinger, R.S.2
Ovaa, H.3
Burg, D.4
Johnson, J.P.5
Frizzell, R.A.6
|