High endothelial venule reporter mice to probe regulation of lymph node vasculature

Advances in Experimental Medicine and Biology

Volumn 691, Issue , 2011, Pages 35-44

  Bentley, Kevin L ^a   Stranford, Sharon ^b   Liao, Shan ^a,c   Mounzer, Rawad M ^a,d   Ruddle, Frank H ^e   Ruddle, Nancy H ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOUNT HOLYOKE COLLEGE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDRESSIN; GREEN FLUORESCENT PROTEIN; LYMPHATIC VESSEL ENDOTHELIAL HYALURONAN RECEPTOR 1; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; OXAZOLONE; PERIPHERAL NODE ADDRESSIN; RECEPTOR; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CARBOHYDRATE SULFOTRANSFERASES; ENHANCED GREEN FLUORESCENT PROTEIN; SULFOTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CHST4 GENE; CONFERENCE PAPER; CONTROLLED STUDY; DEVELOPMENTAL GENE; GENE CONSTRUCT; GENE EXPRESSION SYSTEM; HIGH ENDOTHELIAL VENULE; IMMUNIZATION; IMMUNOREGULATION; LYMPH NODE; LYMPHANGIOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT; REPORTER GENE; VENULE; ANIMAL; ARTICLE; CYTOLOGY; FLUORESCENCE MICROSCOPY; METABOLISM; POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ANIMALS; BIOLOGICAL MARKERS; ENDOTHELIUM, VASCULAR; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; IMMUNIZATION; LYMPH NODES; MICE; MICROSCOPY, FLUORESCENCE; POLYMERASE CHAIN REACTION; SULFOTRANSFERASES; VENULES;

EID: 79954428122     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-6612-4_4     Document Type: Conference Paper

References (19)

1. Ruddle NH, Akirav EM (2009) Secondary lymphoid organs: Responding to genetic and environmental cues in ontogeny and the immune response. J Immunol 183:2205-2212
2. Mebius RE, Streeter PR, Michie S, Butcher EC,Weissman IL (1996) A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+CD3- cells to colonize lymph nodes. Proc Natl Acad Sci 93:11019-11024
3. Bistrup A, Bhakta S, Lee JK, Belov YY, Gunn MD, Zuo FR, Huang CC, Kannagi R, Rosen SD, Hemmerich S (1999) Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. J Cell Biol 145:899-910
4. Hiraoka N, Petryniak B, Nakayama J, Tsuboi S, Suzuki M, Yeh JC, Izawa D, Tanaka T, Miyasaka M, Lowe JB, Fukuda M (1999). A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34. Immunity 11:79-89
5. Cuff CA, Sacca R, Ruddle NH (1999) Differential induction of adhesion molecule and chemokine expression by LTalpha3 and LTalphabeta in inflammation elucidates potential mechanisms of mesenteric and peripheral lymph node development. J Immunol 162: 5965-5972
6. Cuff CA, Schwartz J, Bergman CM, Russell KS, Bender JR, Ruddle NH (1998) Lymphotoxin alpha3 induces chemokines and adhesion molecules: Insight into the role of LT alpha in inflammation and lymphoid organ development. J Immunol 161:6853-6860
7. Drayton DL, Ying X, Lee J, Lesslauer W, Ruddle NH (2003) Ectopic LT alpha beta directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase. J Exp Med 197:1153-1163
8. Kratz A, Campos-Neto A, Hanson MS, Ruddle NH (1996) Chronic inflammation caused by lymphotoxin is lymphoid neogenesis. J Exp Med 183:1461-1472
9. Sacca R, Cuff CA, Lesslauer W, Ruddle NH (1998) Differential activities of secreted lymphotoxin-alpha3 and membrane lymphotoxin-alpha1beta2 in lymphotoxin-induced inflammation: Critical role of TNF receptor 1 signaling. J Immunol 160:485-491
10. Drayton DL, Bonizzi G, Ying X, Liao S, Karin M, Ruddle NH (2004) I kappaB kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue. J Immunol 173:6161-6168
11. Mounzer RM, Svendsen OS, Baluk P, Bergman CM, Padera TP, Wiig H, Jain RK, McDonald DM, Ruddle NH (2010). Lymphotoxin alpha contributes to lymphangiogenesis. Blood June 21 Epub ahead of print.
12. Liao S, Ruddle NH (2006) Synchrony of high endothelial venules and lymphatic vessels revealed by immunization. J Immunol 177:3369-3379
13. DeTogni P, Goellner J, Ruddle NH, Streeter PR, Fick A, Mariathasan S, Smith SC, Carlson R, Shornick LP, Strauss-Schoenberger J et al (1994) Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264:703-707
14. Koni PA, Sacca R, Lawton P, Browning JL, Ruddle NH, Flavell RA (1997) Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin betadeficient mice. Immunity 6:491-500
15. Liao S, Bentley K, Lebrun M, Lesslauer W, Ruddle FH, Ruddle NH (2007) Transgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules. Proc Natl Acad Sci USA 104:4577-4582
16. Bradshaw MS, Bollekens JA, Ruddle FH (1995) A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes. Nucleic Acids Res 23:4850-4856
17. Shashikant CS, Carr JL, Bhargava J, Bentley KL, Ruddle FH (1998) Recombinogenic targeting: A new approach to genomic analysis-a review. Gene 223:9-20
18. Bistrup A, Tsay D, Shenoy P, SingerMS, Bangia N, Luther SA, Cyster JG, Ruddle NH, Rosen SD (2004) Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: Relationship to the MECA-79 epitope. Am J Pathol 164:1635-1644
19. Oliver G (2004) Lymphatic vasculature development. Nat Rev Immunol 4:35-45