Differential induction of adhesion molecule and chemokine expression by LTα3 and LTαβ in inflammation elucidates potential mechanisms of mesenteric and peripheral lymph node development

Journal of Immunology

Volumn 162, Issue 10, 1999, Pages 5965-5972

  Cuff, Carolyn A ^a,b   Sacca, Rosalba ^a,c   Ruddle, Nancy H ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WISTAR INSTITUTE   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDRESSIN; CELL ADHESION MOLECULE; CHEMOKINE; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; LYMPHOTOXIN; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LYMPH NODE; LYMPHOCYTIC INFILTRATION; LYMPHOID TISSUE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; T LYMPHOCYTE ACTIVATION; TRANSGENE;

ANIMALS; ANTIGENS, CD; ANTIGENS, SURFACE; CELL ADHESION MOLECULES; CHEMOKINE CCL2; CHEMOKINES; CHEMOKINES, CXC; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; INFLAMMATION; INFLAMMATION MEDIATORS; ISLETS OF LANGERHANS; LYMPH NODES; LYMPHOTOXIN-ALPHA; MEMBRANE PROTEINS; MESENTERY; MICE; MICE, TRANSGENIC; RANTES; RATS; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I;

EID: 0033563131     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Sacca, R., A. Kratz, A. Campos-Neto, M. S. Hanson, and N. H. Ruddle. 1996. Lymphotoxin: from chronic inflammation to lymphoid organs. J. Inflamm. 47:81.
2. Mooij, P., H. J. d. Wit, and H. A. Drexhage. 1993. An excess of dietary iodine accelerates the development of a thyroid-associated lymphoio tissue in autoimmune prone BB rats. Clin. Immunol. Immunopathol. 69:189.
3. Kratz, A., A. Campos-Neto, M. S. Hanson, and N. H. Ruddle. 1996. Chronic inflammation caused by lymphotoxin is lymphoid neogenesis. J. Exp. Med. 183: 1461.
4. Cannella, B., A. H. Cross, and C. S. Raine. 1990. Upregulation and co-expression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system. J. Exp. Med. 172:1521.
5. Faveeuw, C., M.-C. Gagnerault, and F. Lepault. 1994. Expression of homing and adhesion molecules in infiltrated islets of Langerhans and salivary glands of nonobese diabetic mice. J. Immunol. 152:5969.
6. Ware, C. F., T. L. VanArsdale, P. D. Crowe, and J. L. Browning. 1995. The ligands and receptors of the lymphotoxin system. In Pathways for Cytolysis. G. M. Griffiths and J. Tschopp. eds. Springer-Verlag, Basel, p. 175.
7. De Togni, P., J. Goellner, N. H. Ruddle, P. R. Streeter, A. Fick, S. Mariathasan, S. C. Smith, R. Carlson, L. P. Shornick, J. Strauss-Schoenberger, et al. 1994. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264:703.
8. Banks, T. A., B. T. Rouse, M. K. Kerley, P. J. Blair, V. L. Godfrey, N. A. Kuklin, D. M. Bouley, J. Thomas, S. Kanangat, and M. L. Mucenski. 1995. Lymphotoxin-α-deficient mice: effects on secondary lymphoid organ development and humoral immune responsiveness. J. Immunol. 144:1685.
9. Koni, P. A., R. Sacca, P. Lawton, J. L. Browning, N. H. Ruddle, and R. A. Flavell. 1997 Distinct roles in lymphoid organogenesis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice. Immunity 6:491.
10. Alimzhanov, M. B., D. V. Kuprash, M. H. Kosco-Vilbois, A. Luz, R. L. Turetskaya, A Tarakhovsky, J. Rajewsky, S. A. Nedospasov, and K. Pfeffer. 1997. Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice. Proc. Natl. Acad. Sci. USA 94:9302.
11. Koni, P., and R. Flavell. 1998. A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development: genetic evidence of synergism with lymhotoxin β. J. Exp. Med. 187:1977.
12. Rennert, P., D. James, F. Mackay, J. Browning, and P. Hochman. 1998. Lymph node genesis is induced by signaling through the lymphotoxin β receptor. Immunity 9:71.
13. Picarella, D. E., A. Kratz, C.-b. Li, N. H. Ruddle, and R. A. Flavell. 1992. Insulitis in transgenic mice expressing TNF-β (lymphotoxin) in the pancreas. Proc. Natl. Acad. Sci. USA 89:10036.
14. Shinkai, Y., G. Rathbun, K.-P. Lam, E. Oltz, V. Stewart, M. Mendelsohn, J. Charron, M Datta, F. Young, A. Stall, et al. 1992. Rag-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68: 855.
15. Rothe, J., W. Lesslauer, H. Lotscher, Y. Lang, P. Koebel, F. Kontgen, A. Althage, R. Zinkernagel, M. Steinmetz, and H. Bluethmann. 1993. Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 363:798.
16. Sacca, R., C. A. Cuff, and N. H. Ruddle. 1998. Differential activities of secreted LTα3 and membrane LTα1β2 in lymphotoxin-induced inflammation: critical role of TNFR1 signalling. J. Immunol. 160:485.
17. Springer, T. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301.
18. Cuff, C. A., J. Schwartz, C. M. Bergman, K. Russell, J. Bender, and N. H. Ruddle. 1998. Lymphotoxin α3 induces chemokines and adhesion molecules: insight into the role of LTα in inflammation and lymphoid organ development. J. Immunol. 161:485.
19. Sikorski, E. E., R. Hallmann, E. L. Berg, and E. C. Butcher. 1993. The Peyer's patch high endothelial receptor for lymphocytes, the mucosal vascular addressin, is induced on a murine endothelial cell line by tumor necrosis factor-α and IL-1. J. Immunol. 151:5239.
20. Rollins, B. J. 1997. Chemokines. Blood 90:909.
21. Yoshimura, T., E. A. Robinson, S. Tanaka, E. Appella, and E. J. Leonard. 1989. Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J. Immunol. 142:1956.
22. Rollins, B., A. Walz, and M. Baggiolini. 1991. Recombinant MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood 78:1112.
23. Grewal, I. S., B. J. Rutledge, J. A. Fiorillo, L. Gu, R. P. Gladue, R. A. Flavell, and B. J. Rollins. 1997. Transgenic monocyte chemoattractant protein-1 (MCP-1) in pancreatic islets produces monocyte-rich insulitis without diabetes: abrogation by a second transgene expressing systemic MCP-1. J. Immunol. 159:401.
24. Gunn, M., N. Nelken, X. Lian, and L. Williams. 1997. Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation. J. Immunol. 158:376.
25. Degli-Esposti, M. A., T. Davis-Smith, W. S. Din, P. J. Smolak, R. G. Goodwin, and C. A. Smith. 1997. Activation of the lymphotoxin β receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells. J. Immunol. 158:1756.
26. Carlos, T. A., and J. M. Harlan. 1994. Leukocyte-endothelial adhesion molecules. Blood 84:2068.
27. Williams, N., and E. C. Butcher. 1997. Homing of naive and memory T lymphocyte subsets to Peyer's patches, lymph nodes, and spleen. J. Immunol. 159. 1746.
28. - cells to colonize lymph nodes. Proc. Natl. Acad. Sci. USA 93:11019.
29. + cells that can differentiate to APC, NK cells, and follicular cells, but not T or B cells. Immunity 7:493.
30. Thall, M., B. Petryniak, C. Rogers, P. Smith, R. Marks, R. Kelly, K. Gersten, G. Cheng, T. Saunders, S. Camper, et al. 1996. The α(1, 3) fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell 86:643.
31. Taub, D., D. Longo, and W. Murphy. 1996. Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice. Blood 87:1423.
32. Carr, M. W., S. J. Roth, E. Lutler, S. S. Rose, and T. A. Springer. 1994. Monocyte chemoattractant protein 1 acts as a T lymphocyte chemoattractant. Proc. Natl. Acad. Sci. USA 91:3652.
33. Forster, R., A. E. Mattis, E. Kremmer, E. Wolf, G. Brem, and M. Lipp. 1996. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037.
34. Legler, D., M. Loetscher, R. Roos, I. Clark-Lewis, M. Baggiolini, and B. Moser. 1998. B cell-attracting chemokine1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J. Exp. Med. 187:655.
35. Gunn, M. D., V. N. Ngo, K. M. Ansel, E. H. Ekland, J. G. Cyster, and L. T. Williams. 1998. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature 391:799.
36. Ngo, V. N., H. Korner, M. D. Gunn, K. N. Schmidt, D. S. Riminton, M. D. Cooper, J. L. Browning, J. D. Sedgwick, and J. G. Cyster. 1999. Lymphotoxin α/β and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189:403.