L-DRD4 genotype not associated with sensation seeking, gambling performance and startle reactivity in adolescents: The TRAILS study

Neuropsychologia

Volumn 49, Issue 5, 2011, Pages 1359-1362

  Nederhof, Esther ^a   Creemers, Hanneke E ^b,c   Huizink, Anja C ^c   Ormel, Johan ^a   Oldehinkel, Albertine J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Affective startle modulation; Bangor gambling task; Emotional processing; High Intensity Pleasure; Iowa gambling task; Novelty seeking; Startle amplitude; Temperament; Various number tandem repeat (VNTR)

Indexed keywords

DOPAMINE 4 RECEPTOR;

ADOLESCENT; ARTICLE; BEHAVIOR DISORDER; COHORT ANALYSIS; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DRD4 GENE; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LIMBIC SYSTEM; MAJOR CLINICAL STUDY; MALE; NERVOUS SYSTEM DEVELOPMENT; PATHOLOGICAL GAMBLING; PERSONALITY; POPULATION RESEARCH; PREFRONTAL CORTEX; SENSATION SEEKING BEHAVIOR; STARTLE REFLEX;

ADOLESCENT; ADOLESCENT BEHAVIOR; ANALYSIS OF VARIANCE; CHILD; COHORT STUDIES; FEMALE; GAMBLING; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MINISATELLITE REPEATS; PERSONALITY; PERSONALITY INVENTORY; RECEPTORS, DOPAMINE D4; RISK FACTORS; SENSATION; STARTLE REACTION;

EID: 79954425626     PISSN: 00283932     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2011.02.019     Document Type: Article

References (22)

1. Blumenthal T.D., Cuthbert B.N., Filion D.L., Hackley S., Lipp O.V., Van Boxtel A. Committee report: Guidelines for human startle eyeblink electromyographic studies. Psychophysiology 2005, 42:1-15.
2. Bouma E.M.C., Riese H., Ormel J., Verhulst F.C., Oldehinkel A.J. Adolescents' cortisol responses to awakening and social stress; effects of gender, menstrual phase and oral contraceptives. The TRAILS study. Psychoneuroendocrinology 2009, 34:884-893.
3. Bowman C.H., Turnbull O.H. Emotion-based learning on a simplified card game: The Iowa and Bangor gambling tasks. Brain and Cognition 2004, 55:277-282.
4. Bradley M.M., Lang P.J. Measuring emotion - The self-assessment mannequin and the semantic differential. Journal of Behavior Therapy and Experimental Psychiatry 1994, 25:49-59.
5. Casey B.J., Getz S., Galvan A. The adolescent brain. Developmental Review 2008, 28:62-77.
6. Caspi A., Roberts B.W., Shiner R.L. Personality development: Stability and change. Annual Review of Psychology 2005, 56:453-484.
7. Costa P.T.J., McCrae R.R. Revised NEO personality inventory (NEO-PI-R) and the five factor inventory (NEO-FFI): Professional manual 1992, Psychological Assessment Resources Inc., Odessa, Florida.
8. Crone E.A., van der Molen M.W. Developmental changes in real life decision making: Performance on a gambling task previously shown to depend on the ventromedial prefrontal cortex. Developmental Neuropsychology 2004, 25:251-279.
9. de Winter A., Oldehinkel A.J., Veenstra R., Brunnekreef J.A., Verhulst F.C., Ormel J. Evaluation of non-response bias in mental health determinants and outcomes in a large sample of pre-adolescents. European Journal of Epidemiology 2005, 20:173-181.
10. Hoekstra H.A., Ormel J., De Fruyt F. NEO-PI-R en NEO-FFI persoonlijkheidsvragenlijsten: Handleiding 2007, Hogrefe Uitgevers B.B, Amsterdam.
11. Huisman M., Oldehinkel A.J., de Winter A., Minderaa R.B., de Bildt A., Huizink A.C., et al. Cohort profile: The Dutch TRacking adolescents individual lives survey; TRAILS. International Journal of Epidemiology 2008, 37:1227-1235.
12. Laucht M., Becker K., El-Faddagh M., Hohm E., Schmidt M.H. Association of the DRD4 exon III polymorphism with smoking in fifteen-year-olds: A mediating role for novelty seeking?. Journal of the American Academy of Child and Adolescent Psychiatry 2005, 44:477-484.
13. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Research 1988, 16:1215-11215.
14. Missale C., Nash S.R., Robinson S.W., Jaber M., Caron M.G. Dopamine receptors: From structure to function. Physiological Reviews 1998, 78:189-225.
15. Munafo M.R., Yalcin B., Willis-Owen S.A., Flint J. Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: Metaanalysis and new data. Biological Psychiatry 2008, 63:197-206.
16. Oak J.N., Oldenhof J., Van Tol H.H.M. The dopamine D-4 receptor: One decade of research. European Journal of Pharmacology 2000, 405:303-327.
17. Oldehinkel A.J., Hartman C.A., De Winter A.F., Veenstra R., Ormel J. Temperament profiles associated with internalizing and externalizing problems in preadolescence. Development and Psychopathology 2004, 16:421-440.
18. Pauli P., Conzelmann A., Mucha R.F., Weyers P., Baehne C.G., Fallgatter A.J., et al. Affect-modulated startle reflex and dopamine D4 receptor gene variation. Psychophysiology 2010, 47:25-33.
19. Roussos P., Giakoumaki S.G., Bitsios P. Cognitive and emotional processing in high novelty seeking associated with the L-DRD4 genotype. Neuropsychologia 2009, 47:1654-1659.
20. Steinberg L., Albert D., Cauffman E., Banich M., Graham S., Woolard J. Age differences in sensation seeking and impulsivity as indexed by behavior and self-report: Evidence for a dual systems model. Developmental Psychology 2008, 44:1764-1778.
21. van Goozen S.H.M., Snoek H., Matthys W., van Rossum I., van Engeland H. Evidence of fearlessness in behaviourally disordered children: A study on startle reflex modulation. Journal of Child Psychology and Psychiatry 2004, 45:884-892.
22. Waters A.M., Lipp O.V., Spence S.H. The effects of affective picture stimuli on blink modulation in adults and children. Biological Psychology 2005, 68:257-281.