Efficacy and safety of propranolol as first-line treatment for infantile hemangiomas

European Journal of Pediatrics

Volumn 170, Issue 4, 2011, Pages 493-501

  Schiestl, Clemens ^a   Neuhaus, Kathrin ^a   Zoller, Silke ^a   Subotic, Ulrike ^a   Forster Kuebler, Ishilde ^a   Michels, Rike ^b   Balmer, Christian ^a   Weibel, Lisa ^a,c  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Betareceptor antagonist; Children; Hemangioma; Infantile; Propranolol

Indexed keywords

PROPRANOLOL;

AMBLYOPIA; ANXIETY; ARTICLE; ASTIGMATISM; BRADYCARDIA; CAPILLARY HEMANGIOMA; CHILD; CLINICAL ARTICLE; DIASTOLIC BLOOD PRESSURE; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERANCE; FEMALE; FOLLOW UP; HEMODYNAMICS; HUMAN; INFANT; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; QT PROLONGATION; SIDE EFFECT; SLEEP DISORDER; SOMNOLENCE; SYSTOLIC BLOOD PRESSURE; TREATMENT RESPONSE; ULTRASOUND; VISUAL ANALOG SCALE;

ADRENERGIC BETA-ANTAGONISTS; BLOOD PRESSURE; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEART RATE; HEMANGIOMA; HUMANS; INFANT; MALE; PROPRANOLOL; RETROSPECTIVE STUDIES; SKIN NEOPLASMS; TREATMENT OUTCOME;

EID: 79954425506     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-010-1324-2     Document Type: Article

References (19)

1. ML Bennett AB Fleischer Jr SL Chamlin IJ Frieden 2001 Oral corticosteroid use is effective for cutaneous hemangiomas: an evicence-based evaluation Arch Dermatol 137 1208 1213 11559219 1:CAS:528:DC%2BD3MXnt12lsrs%3D (Pubitemid 32847844)
2. AL Bruckner IJ Frieden 2003 Hemangiomas of infancy J Am Acad Dermatol 48 477 493 12664009 10.1067/mjd.2003.200 (Pubitemid 36397008)
3. LM Buckmiller PD Munson U Dyamenahalli, et al. 2010 Propranolol for infantile hemangiomas: early experience at a tertiary vascular anomalies center Laryngoscope 120 676 681 20112413 10.1002/lary.20807 1:CAS:528: DC%2BC3cXlslWkt7s%3D
4. EH Garin CE Araya 2009 Treatment of systemic hypertension in children and adolescents Curr Opin Pediatr 21 600 604 19606039 10.1097/MOP.0b013e32832ff3a7
5. AN Haggstrom BA Drolet E Baselga, et al. 2006 Prospective study of infantile hemangiomas: clinical characteristics predicting complications and treatment Pediatrics 118 882 887 16950977 10.1542/peds.2006-0413 (Pubitemid 46091612)
6. AN Haggstrom BA Drolet E Baselga, et al. 2007 Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics J Pediatr 150 291 294 17307549 10.1016/j.jpeds.2006.12.003 (Pubitemid 46328964)
7. KE Holland IJ Frieden PC Frommelt, et al. 2010 Hypoglycaemia in children taking propranolol for the treatment of infantile hemangioma Arch Dermatol 146 775 778 20644039 10.1001/archdermatol.2010.158 1:CAS:528:DC%2BC3cXhtVClsLbJ
8. AL Kent Z Kecskes B Shadbolt MC Falk 2007 Blood pressure in the first year of life in healthy infants born at term Pediatr Nephrol 22 1743 1749 17680275 10.1007/s00467-007-0561-8 (Pubitemid 47337430)
9. C Kilcline IJ Frieden 2008 Infantile hemangiomas: how common are they? a systematic review of the medical literature Pediatr Dermatol 25 168 173 18429772 10.1111/j.1525-1470.2008.00626.x (Pubitemid 351579596)
10. N Laforgia A Milano E De Leo E Bonifazi 2009 Hemangioma and propranolol. Some remarks at the end of treatment. Differences from corticosteroids Eur J Pediat Dermatol 19 175 191
11. LP Lawley E Siegfried JL Todd 2009 Propranolol treatment for hemangioma of infancy: risks and recommendations Pediatr Dermatol 26 610 614 19840322 10.1111/j.1525-1470.2009.00975.x
12. C Léauté-Labrèze E Dumas de la Roque T Hubiche, et al. 2008 Propranolol for severe hemangiomas of infancy N Engl J Med 358 2649 2651 18550886 10.1056/NEJMc0708819 (Pubitemid 351831393)
13. JN Love N Sikka 2004 Are 1-2 tablets dangerous? beta-blocker exposure in toddlers J Emerg Med 26 309 314 15028329 10.1016/j.jemermed.2003.11.015 (Pubitemid 38340830)
14. F Manunza S Syed B Laguda, et al. 2010 Propranolol for complicated infantile haemangiomas: a case series of 30 infants Br J Dermatol 162 466 468 20055816 10.1111/j.1365-2133.2009.09597.x 1:STN:280:DC%2BC3c3ksVGitA%3D%3D
15. AP Michaud NM Baumann DK Burke, et al. 2004 Spastic diplegia and other motor disturbances in infants receiving interferon-alpha Laryngoscope 114 1231 1236 15235352 10.1097/00005537-200407000-00017 1:CAS:528:DC%2BD2cXltlOrtbs%3D (Pubitemid 38954577)
16. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents 2004 The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents Pediatrics 114 555 576 10.1542/peds.114.2.S2.555 (Pubitemid 39006657)
17. ZP Qin XJ Liu KL Li, et al. 2009 Treatment of infantile hemangiomas with low-dose propranolol: evaluation of short-term efficacy and safety Zhonghua Yi Xue Za Zhi 89 3230 3234
18. V Sans E Dumas de la Roque J Berge, et al. 2009 Propranolol for severe infantile hemangiomas: follow up-report Pediatrics 124 423 431 10.1542/peds.2008-3458
19. CH Storch PH Hoeger 2010 Propranolol for infantile haemangiomas-insights into the molecular mechanisms of action Br J Dermatol 163 269 274 20456345 10.1111/j.1365-2133.2010.09848.x 1:CAS:528:DC%2BC3cXhtFCgtbfP