Treatment of systemic hypertension in children and adolescents

Current Opinion in Pediatrics

Volumn 21, Issue 5, 2009, Pages 600-604

  Garin, Eduardo H ^a   Araya, Carlos E ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Ambulatory blood pressure monitor; Angiotensin II receptor blocker; Obesity; Uric acid

Indexed keywords

ALLOPURINOL; ALPHA 2 ADRENERGIC RECEPTOR; AMILORIDE; AMLODIPINE; ANGIOTENSIN 1 RECEPTOR; ATENOLOL; BENAZEPRIL; CAPTOPRIL; CARVEDILOL; CHLOROTHIAZIDE; CLONIDINE; ENALAPRIL; FOSINOPRIL; FUROSEMIDE; HYDRALAZINE; HYDROCHLOROTHIAZIDE; IRBESARTAN; ISRADIPINE; LABETALOL; LISINOPRIL; LOSARTAN; METHYLDOPA; METOPROLOL; MINOXIDIL; NIFEDIPINE; PRAZOSIN; PROPRANOLOL; SPIRONOLACTONE; UNINDEXED DRUG; VALSARTAN;

ADOLESCENT; ANTIHYPERTENSIVE ACTIVITY; ANTIHYPERTENSIVE THERAPY; BLOOD PRESSURE MONITORING; CHILD; DIET THERAPY; DRUG CHOICE; EXERCISE; HUMAN; HYPERTENSION; HYPERTENSIVE CRISIS; LIFESTYLE MODIFICATION; OBESITY; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; REVIEW; URIC ACID BLOOD LEVEL;

ADOLESCENT; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BLOOD PRESSURE MONITORING, AMBULATORY; CARDIOVASCULAR AGENTS; CHILD; DIET; DIURETICS; EXERCISE; HUMANS; HYPERTENSION;

EID: 71849087600     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOP.0b013e32832ff3a7     Document Type: Review

References (11)

1. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2005). The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. National, heart, lung, and blood institute, Bethesda, Maryland. National Institute of Health, NIH publication 05: 5267.
2. Acosta AA, McNiece KL. Ambulatory blood pressure monitoring: a versatile tool for evaluating and managing hypertension in children. Pediatr Nephrol 2008; 23:1399-1408. This study is a good summary of the current approach and validity of the use of ABPM in hypertensive patients.
3. Diaz LN, Garin EH. Comparison of ambulatory blood pressure and task force criteria to identify hypertension. Pediatr Nephrol 2007; 22:554-558.
4. Ahmed M, Eggleston D, Kapur G, et al. Dimercaptosuccinic acid (DMSA) renal scan in the evaluation of hypertension in children. Pediatr Nephrol 2008; 23:435-438.
5. Falkner B. Hypertension in children and adolescents: epidemiology and natural history. Pediatr Nephrol 2009. [Epub ahead of print] The author, among other issues, gives an excellent overview on the meaning of normative blood pressure data as well as the role of obesity in the 'epidemic' of hypertension.
6. Feig DI, Soletsky B, Johnson RJ. Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial. J Am Med Assoc 2008; 300:924-932. A rather tantalizing observation. Needs confirmation with larger numbers of patients but may have major clinical significance regarding mechanism and consequently treatment of hypertension.
7. Sakuragi S, Abhayaratna K, Gravenmaker KJ, et al. Influence of adiposity and physical activity on arterial stiffness in healthy children: the Lifestyle of Our Kids Study. Hypertension 2009; 53:611-616.
8. Blumenfeld JD, Laragh JH. Renin system analysis: a rational method for the diagnosis and treatment of the individual patient with hypertension. Am J Hypertens 1998; 11:894-896.
9. Egan BM, Basile JN, Rehman SU, et al. Plasma renin test-guided treatment algorithm for correcting patients with treated but uncontrolled hypertension. A randomized controlled trial. Am J Hypertens 2009; 22:792-801. A randomized trial that supports the concept of different pathophysiologic mechanisms for hypertension and the need to administer medications accordingly.
10. Croix B, Feig DI. Childhood hypertension is not a silent disease. Pediatr Nephrol 2006; 21:527-532.
11. Gaddam KK, Nishizaka MK, Pratt-Ubunama MN, et al. Characterization of resistant hypertension; association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. Arch Intern Med 2008; 9:1159-1164.