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Volumn 88, Issue 4, 2011, Pages 304-313

Predictors of bone responsiveness to growth hormone (GH) replacement in adult GH-deficient patients

Author keywords

Adult GH deficiency; Bone; GH replacement therapy

Indexed keywords

CALCIUM; HUMAN GROWTH HORMONE; HUMATOTROPE; OSTEOCALCIN; PARATHYROID HORMONE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

EID: 79954418834     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-010-9459-8     Document Type: Article
Times cited : (10)

References (38)
  • 2
    • 0030882291 scopus 로고    scopus 로고
    • Increased fracture frequency in adult patients with hypopituitarism and GH deficiency
    • DOI 10.1530/eje.0.1370240
    • T Rosen L Wilhelmsen K Landin-Wilhelmsen G Lappas BA Bengtsson 1997 Increased fracture frequency in adult patients with hypopituitarism and GH deficiency Eur J Endocrinol 137 240 245 9330587 10.1530/eje.0.1370240 1:CAS:528:DyaK2sXntVyksLs%3D (Pubitemid 27405107)
    • (1997) European Journal of Endocrinology , vol.137 , Issue.3 , pp. 240-245
    • Rosen, T.1    Wilhelmsen, L.2    Landin-Wilhelmsen, K.3    Lappas, G.4    Bengtsson, B.-A.5
  • 3
    • 33645330427 scopus 로고    scopus 로고
    • Increased prevalence of radiological spinal deformities in adult patients with GH deficiency: Influence of GH replacement therapy
    • 16598371 10.1359/jbmr.060112 1:CAS:528:DC%2BD28Xkt1Kqsrk%3D
    • G Mazziotti A Bianchi S Bonadonna M Nuzzo V Cimino A Fusco L De Marinis A Giustina 2006 Increased prevalence of radiological spinal deformities in adult patients with GH deficiency: influence of GH replacement therapy J Bone Miner Res 21 520 528 16598371 10.1359/jbmr.060112 1:CAS:528:DC%2BD28Xkt1Kqsrk%3D
    • (2006) J Bone Miner Res , vol.21 , pp. 520-528
    • Mazziotti, G.1    Bianchi, A.2    Bonadonna, S.3    Nuzzo, M.4    Cimino, V.5    Fusco, A.6    De Marinis, L.7    Giustina, A.8
  • 5
    • 0027363782 scopus 로고
    • Reduced bone mineral content in adult patients with growth hormone deficiency
    • T Rosen T Hansson H Granhed J Szucs BA Bengtsson 1993 Reduced bone mineral content in adult patients with growth hormone deficiency Acta Endocrinol (Copenh) 129 201 206 1:STN:280:DyaK2c%2Fis1SqtA%3D%3D (Pubitemid 23295680)
    • (1993) Acta Endocrinologica , vol.129 , Issue.3 , pp. 201-206
    • Rosen, T.1    Hansson, T.2    Granhed, H.3    Szucs, J.4    Bengtsson, B.-A.5
  • 6
    • 0028832010 scopus 로고
    • Abnormal body composition and reduced bone mass in growth hormone deficient hypopituitary adults
    • 10.1111/j.1365-2265.1995.tb01860.x 1:STN:280:DyaK2M3hvF2jsg%3D%3D
    • SA Beshyah C Freemantle E Thomas O Rutherford B Page M Murphy DG Johnston 1995 Abnormal body composition and reduced bone mass in growth hormone deficient hypopituitary adults Clin Endocrinol (Oxf) 42 179 189 10.1111/j.1365-2265.1995.tb01860.x 1:STN:280:DyaK2M3hvF2jsg%3D%3D
    • (1995) Clin Endocrinol (Oxf) , vol.42 , pp. 179-189
    • Beshyah, S.A.1    Freemantle, C.2    Thomas, E.3    Rutherford, O.4    Page, B.5    Murphy, M.6    Johnston, D.G.7
  • 7
    • 33751174502 scopus 로고    scopus 로고
    • Bone mineral density in patients with growth hormone deficiency: Does a gender difference exist?
    • DOI 10.1111/j.1365-2265.2006.02667.x
    • MF Hitz JE Jensen PC Eskildsen 2006 Bone mineral density in patients with growth hormone deficiency: does a gender difference exist? Clin Endocrinol (Oxf) 65 783 791 10.1111/j.1365-2265.2006.02667.x 1:CAS:528: DC%2BD2sXptVWgsw%3D%3D (Pubitemid 44773691)
    • (2006) Clinical Endocrinology , vol.65 , Issue.6 , pp. 783-791
    • Hitz, M.F.1    Jensen, J.-E.B.2    Eskildsen, P.C.3
  • 9
    • 0029812889 scopus 로고    scopus 로고
    • Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency
    • DOI 10.1210/jc.81.8.2865
    • G Johannsson T Rosen I Bosaeus L Sjostrom BA Bengtsson 1996 Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency J Clin Endocrinol Metab 81 2865 2873 8768843 10.1210/jc.81.8.2865 1:CAS:528:DyaK28XkvFWrsLs%3D (Pubitemid 26323877)
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , Issue.8 , pp. 2865-2873
    • Johannsson, G.1    Rosen, T.2    Bosaeus, I.3    Sjostrom, L.4    Bengtsson, B.-A.5
  • 10
    • 18244420046 scopus 로고    scopus 로고
    • Effects of 42 months of GH treatment on bone mineral density and bone turnover in GH-deficient adults
    • DOI 10.1530/eje.0.1400545
    • MJ Valimaki PI Salmela J Salmi J Viikari M Kataja H Turunen E Soppi 1999 Effects of 42 months of GH treatment on bone mineral density and bone turnover in GH-deficient adults Eur J Endocrinol 140 545 554 10377504 10.1530/eje.0.1400545 1:CAS:528:DyaK1MXktlCnur4%3D (Pubitemid 29314717)
    • (1999) European Journal of Endocrinology , vol.140 , Issue.6 , pp. 545-554
    • Valimaki, M.J.1    Salmela, P.I.2    Salmi, J.3    Viikari, J.4    Kataja, M.5    Turunen, H.6    Soppi, E.7
  • 11
    • 0030786517 scopus 로고    scopus 로고
    • Growth hormone substitution in adult growth hormone-deficient men augments androgen effects on the skin
    • GJ Blok H de Boer LJ Gooren EA van der Veen 1997 Growth hormone substitution in adult growth hormone-deficient men augments androgen effects on the skin Clin Endocrinol (Oxf) 47 29 36 10.1046/j.1365-2265.1997.2021027.x 1:CAS:528:DyaK2sXls1Wjur8%3D (Pubitemid 27313985)
    • (1997) Clinical Endocrinology , vol.47 , Issue.1 , pp. 29-36
    • Blok, G.J.1    De Boer, H.2    Gooren, L.J.G.3    Van Der Veen, E.A.4
  • 12
    • 0031832496 scopus 로고    scopus 로고
    • Sexual dimorphism of the somatotrophic axis
    • DOI 10.1677/joe.0.1570373
    • KL Gatford AR Egan IJ Clarke PC Owens 1998 Sexual dimorphism of the somatotrophic axis J Endocrinol 157 373 389 9691971 10.1677/joe.0.1570373 1:CAS:528:DyaK1cXktlKqtbY%3D (Pubitemid 28275837)
    • (1998) Journal of Endocrinology , vol.157 , Issue.3 , pp. 373-389
    • Gatford, K.L.1    Egan, A.R.2    Clarke, I.J.3    Owens, P.C.4
  • 13
    • 32544438281 scopus 로고    scopus 로고
    • Clinical review: Sex steroids and the periosteum - Reconsidering the roles of androgens and estrogens in periosteal expansion
    • DOI 10.1210/jc.2005-1766
    • D Vanderschueren K Venken J Ophoff R Bouillon S Boonen 2006 Sex steroids and the periosteum-reconsidering the roles of androgens and estrogens in periosteal expansion J Clin Endocrinol Metab 91 378 382 16303833 10.1210/jc.2005-1766 1:CAS:528:DC%2BD28XhsFKnt7o%3D (Pubitemid 43236896)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.2 , pp. 378-382
    • Vanderschueren, D.1    Venken, K.2    Ophoff, J.3    Bouillon, R.4    Boonen, S.5
  • 15
    • 0034749231 scopus 로고    scopus 로고
    • A prospective study of 5 years of GH replacement therapy in GH-deficient adults: Sustained effects on body composition, bone mass, and metabolic indices
    • DOI 10.1210/jc.86.10.4657
    • G Gotherstrom J Svensson J Koranyi M Alpsten I Bosaeus B Bengtsson G Johannsson 2001 A prospective study of 5 years of GH replacement therapy in GH-deficient adults: sustained effects on body composition, bone mass, and metabolic indices J Clin Endocrinol Metab 86 4657 4665 11600522 10.1210/jc.86.10.4657 1:CAS:528:DC%2BD3MXptVaku7c%3D (Pubitemid 33026070)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.10 , pp. 4657-4665
    • Gotherstrom, G.1    Svensson, J.2    Koranyi, J.3    Alpsten, M.4    Bosaeus, I.5    Bengtsson, B.-A.6    Johannsson, G.7
  • 16
    • 0033305346 scopus 로고    scopus 로고
    • Gender differences in the effects of long term growth hormone (GH) treatment on bone in adults with GH deficiency
    • AG Johansson BE Engstrom S Ljunghall FA Karlsson P Burman 1999 Gender differences in the effects of long term growth hormone (GH) treatment on bone in adults with GH deficiency J Clin Endocrinol Metab 84 2002 2007 10372701 10.1210/jc.84.6.2002 1:CAS:528:DyaK1MXjs1OhsrY%3D (Pubitemid 30647025)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.6 , pp. 2002-2007
    • Johansson, A.G.1    Engstrom, B.E.2    Ljunghall, S.3    Karlsson, F.A.4    Burman, P.5
  • 17
    • 0032617503 scopus 로고    scopus 로고
    • Gender difference in growth hormone response in adults
    • 10442572 1:STN:280:DyaK1MzmvFWktA%3D%3D
    • AG Johansson 1999 Gender difference in growth hormone response in adults J Endocrinol Invest 22 58 60 10442572 1:STN:280:DyaK1MzmvFWktA%3D%3D
    • (1999) J Endocrinol Invest , vol.22 , pp. 58-60
    • Johansson, A.G.1
  • 18
    • 0035723728 scopus 로고    scopus 로고
    • The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: A 5-year study
    • DOI 10.1046/j.1365-2265.2001.01246.x
    • WM Drake J Rodriguez-Arnao JU Weaver IT James D Coyte TD Spector GM Besser JP Monson 2001 The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5-year study Clin Endocrinol (Oxf) 54 525 532 10.1046/j.1365-2265.2001.01246.x 1:CAS:528:DC%2BD3MXktFKhsLk%3D (Pubitemid 34207705)
    • (2001) Clinical Endocrinology , vol.54 , Issue.4 , pp. 525-532
    • Drake, W.M.1    Rodriguez-Arnao, J.2    Weaver, J.U.3    James, I.T.4    Coyte, D.5    Spector, T.D.6    Besser, G.M.7    Monson, J.P.8
  • 19
    • 0035999443 scopus 로고    scopus 로고
    • The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: A 2-year open randomized controlled multicenter trial
    • M Bex R Abs D Maiter A Beckers G Lamberigts R Bouillon 2002 The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: a 2-year open randomized controlled multicenter trial J Bone Miner Res 17 1081 1094 12054164 10.1359/jbmr.2002.17.6.1081 1:CAS:528:DC%2BD38Xks1Wktbo%3D (Pubitemid 34535147)
    • (2002) Journal of Bone and Mineral Research , vol.17 , Issue.6 , pp. 1081-1094
    • Bex, M.1    Abs, R.2    Maiter, D.3    Beckers, A.4    Lamberigts, G.5    Bouillon, R.6
  • 21
    • 42649103615 scopus 로고    scopus 로고
    • Bone density and turnover in young adult patients with growth hormone deficiency after 2-year growth hormone replacement according with gender
    • 18362499 1:CAS:528:DC%2BD1cXmt1ems7c%3D
    • F Rota MC Savanelli L Tauchmanova S Savastano G Lombardi A Colao C Di Somma 2008 Bone density and turnover in young adult patients with growth hormone deficiency after 2-year growth hormone replacement according with gender J Endocrinol Invest 31 94 102 18362499 1:CAS:528:DC%2BD1cXmt1ems7c%3D
    • (2008) J Endocrinol Invest , vol.31 , pp. 94-102
    • Rota, F.1    Savanelli, M.C.2    Tauchmanova, L.3    Savastano, S.4    Lombardi, G.5    Colao, A.6    Di Somma, C.7
  • 22
    • 42649112056 scopus 로고    scopus 로고
    • Official Positions of the International Society for Clinical Densitometry and Executive Summary of the 2007 ISCD Position Development Conference
    • DOI 10.1016/j.jocd.2007.12.007, PII S1094695007002557
    • S Baim N Binkley JP Bilezikian DL Kendler DB Hans EM Lewiecki S Silverman 2008 Official positions of the International Society for Clinical Densitometry and executive summary of the 2007 ISCD Position Development Conference J Clin Densitom 11 75 91 18442754 10.1016/j.jocd.2007.12.007 (Pubitemid 351602189)
    • (2008) Journal of Clinical Densitometry , vol.11 , Issue.1 , pp. 75-91
    • Baim, S.1    Binkley, N.2    Bilezikian, J.P.3    Kendler, D.L.4    Hans, D.B.5    Lewiecki, E.M.6    Silverman, S.7
  • 23
    • 0002020058 scopus 로고    scopus 로고
    • Influence of gender on response to growth hormone substitution therapy in adults with growth hormone deficiency
    • J. Veldhuis A. Giustina (eds). Springer New York
    • Roelfsema F, Janssen YJ (1999) Influence of gender on response to growth hormone substitution therapy in adults with growth hormone deficiency. In: Veldhuis J, Giustina A (eds) Sex steroid interactions with growth hormone. Springer, New York, pp 209-218
    • (1999) Sex Steroid Interactions with Growth Hormone , pp. 209-218
    • Roelfsema, F.1    Janssen, Y.J.2
  • 24
    • 0034751043 scopus 로고    scopus 로고
    • Baseline characteristics and the effects of five years of GH replacement therapy in adults with GH deficiency of childhood or adulthood onset: A comparative, prospective study
    • DOI 10.1210/jc.86.10.4693
    • J Koranyi J Svensson G Gotherstrom KS Sunnerhagen B Bengtsson G Johannsson 2001 Baseline characteristics and the effects of five years of GH replacement therapy in adults with GH deficiency of childhood or adulthood onset: a comparative, prospective study J Clin Endocrinol Metab 86 4693 4699 11600527 10.1210/jc.86.10.4693 1:CAS:528:DC%2BD3MXptVarsro%3D (Pubitemid 33026071)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.10 , pp. 4693-4699
    • Koranyi, J.1    Svensson, J.2    Gotherstrom, G.3    Sunnerhagen, K.S.4    Bengtsson, B.-A.5    Johannsson, G.6
  • 25
    • 49549111375 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factors, and the skeleton
    • 18436706 10.1210/er.2007-0036 1:CAS:528:DC%2BD1cXhtVKnsrvL
    • A Giustina G Mazziotti E Canalis 2008 Growth hormone, insulin-like growth factors, and the skeleton Endocr Rev 29 535 559 18436706 10.1210/er.2007-0036 1:CAS:528:DC%2BD1cXhtVKnsrvL
    • (2008) Endocr Rev , vol.29 , pp. 535-559
    • Giustina, A.1    Mazziotti, G.2    Canalis, E.3
  • 26
    • 0036359122 scopus 로고    scopus 로고
    • Evaluation of the optimum dose of growth hormone (GH) for restoring bone mass in adult-onset GH deficiency: Results from two 12-month randomized studies
    • DOI 10.1046/j.1365-2265.2002.01582.x
    • B Abrahamsen J Hangaard HC Horn TB Hansen G Gregersen M Hansen-Nord N Vahl P Junker M Andersen C Hagen 2002 Evaluation of the optimum dose of growth hormone (GH) for restoring bone mass in adult-onset GH deficiency: results from two 12-month randomized studies Clin Endocrinol (Oxf) 57 273 281 10.1046/j.1365-2265.2002.01582.x 1:CAS:528:DC%2BD38XntFyrtr4%3D (Pubitemid 34989105)
    • (2002) Clinical Endocrinology , vol.57 , Issue.2 , pp. 273-281
    • Abrahamsen, B.1    Hangaard, J.2    Horn, H.C.3    Hansen, T.B.4    Gregersen, G.5    Hansen-Nord, M.6    Vahl, N.7    Junker, P.8    Andersen, M.9    Hagen, C.10
  • 27
    • 2442692724 scopus 로고    scopus 로고
    • Long-term skeletal effects of recombinant human growth hormone (rhGH) alone and rhGH combined with alendronate in GH-deficient adults: A seven-year follow-up study
    • DOI 10.1111/j.1365-2265.2004.02021.x
    • NR Biermasz NA Hamdy AM Pereira JA Romijn F Roelfsema 2004 Long-term skeletal effects of recombinant human growth hormone (rhGH) alone and rhGH combined with alendronate in GH-deficient adults: a seven-year follow-up study Clin Endocrinol (Oxf) 60 568 575 10.1111/j.1365-2265.2004.02021.x 1:CAS:528:DC%2BD2cXltFWqur4%3D (Pubitemid 38669846)
    • (2004) Clinical Endocrinology , vol.60 , Issue.5 , pp. 568-575
    • Biermasz, N.R.1    Hamdy, N.A.T.2    Pereira, A.M.3    Romijn, J.A.4    Roelfsema, F.5
  • 28
    • 0036075085 scopus 로고    scopus 로고
    • Effects of 12 months of GH treatment on cortical and trabecular bone content of IGFs and OPG in adults with acquired GH deficiency: A double-blind, randomized, placebo-controlled study
    • DOI 10.1210/jc.87.6.2760
    • T Ueland J Bollerslev A Flyvbjerg TB Hansen N Vahl L Mosekilde 2002 Effects of 12 months of GH treatment on cortical and trabecular bone content of IGFs and OPG in adults with acquired GH deficiency: a double-blind, randomized, placebo-controlled study J Clin Endocrinol Metab 87 2760 2763 12050246 10.1210/jc.87.6.2760 1:CAS:528:DC%2BD38XkvFaktbY%3D (Pubitemid 34655341)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.6 , pp. 2760-2763
    • Ueland, T.1    Bollerslev, J.2    Flyvbjerg, A.3    Hansen, T.B.4    Vahl, N.5    Mosekilde, L.6
  • 30
    • 0037292935 scopus 로고    scopus 로고
    • GH replacement therapy increases plasma osteoprotegerin levels in GH-deficient adults
    • DOI 10.1530/eje.0.1480185
    • R Lanzi M Losa I Villa E Gatti M Sirtori FC Dal A Rubinacci 2003 GH replacement therapy increases plasma osteoprotegerin levels in GH-deficient adults Eur J Endocrinol 148 185 191 12590637 10.1530/eje.0.1480185 1:CAS:528:DC%2BD3sXhvF2jtL0%3D (Pubitemid 36312939)
    • (2003) European Journal of Endocrinology , vol.148 , Issue.2 , pp. 185-191
    • Lanzi, R.1    Losa, M.2    Villa, I.3    Gatti, E.4    Sirtori, M.5    Dal Fiume, C.6    Rubinacci, A.7
  • 31
    • 33947394915 scopus 로고    scopus 로고
    • Growth hormone stimulates osteoprotegerin expression and secretion in human osteoblast-like cells
    • DOI 10.1677/joe.1.07073
    • E Mrak I Villa R Lanzi M Losa F Guidobono A Rubinacci 2007 Growth hormone stimulates osteoprotegerin expression and secretion in human osteoblast-like cells J Endocrinol 192 639 645 17332531 10.1677/joe.1.07073 1:CAS:528: DC%2BD2sXktFGmsbg%3D (Pubitemid 46455966)
    • (2007) Journal of Endocrinology , vol.192 , Issue.3 , pp. 639-645
    • Mrak, E.1    Villa, I.2    Lanzi, R.3    Losa, M.4    Guidobono, F.5    Rubinacci, A.6
  • 32
    • 5544328189 scopus 로고    scopus 로고
    • Estrogen regulation of growth hormone action
    • DOI 10.1210/er.2003-0035
    • KC Leung G Johannsson GM Leong KK Ho 2004 Estrogen regulation of growth hormone action Endocr Rev 25 693 721 15466938 10.1210/er.2003-0035 1:CAS:528:DC%2BD2cXhtVSjtrnN (Pubitemid 39366048)
    • (2004) Endocrine Reviews , vol.25 , Issue.5 , pp. 693-721
    • Leung, K.-C.1    Johannsson, G.2    Leong, G.M.3    Ho, K.K.Y.4
  • 33
    • 68349146822 scopus 로고    scopus 로고
    • Is increase in bone mineral content caused by increase in skeletal muscle mass/strength in adult patients with GH-treated GH deficiency? A systematic literature analysis
    • 19439507 10.1530/EJE-09-0160 1:CAS:528:DC%2BD1MXpvVyku7g%3D
    • O Klefter U Feldt-Rasmussen 2009 Is increase in bone mineral content caused by increase in skeletal muscle mass/strength in adult patients with GH-treated GH deficiency? A systematic literature analysis Eur J Endocrinol 161 213 221 19439507 10.1530/EJE-09-0160 1:CAS:528:DC%2BD1MXpvVyku7g%3D
    • (2009) Eur J Endocrinol , vol.161 , pp. 213-221
    • Klefter, O.1    Feldt-Rasmussen, U.2
  • 34
    • 70349739077 scopus 로고    scopus 로고
    • Influence of long-term growth hormone replacement on leptin and ghrelin in GH deficiency before and after glucose load
    • 19596030 10.1016/j.regpep.2009.07.001 1:CAS:528:DC%2BD1MXht1GgurrL
    • J Roemmler M Kuenkler B Otto AM Arafat M Bidlingmaier J Schopohl 2009 Influence of long-term growth hormone replacement on leptin and ghrelin in GH deficiency before and after glucose load Regul Pept 158 40 46 19596030 10.1016/j.regpep.2009.07.001 1:CAS:528:DC%2BD1MXht1GgurrL
    • (2009) Regul Pept , vol.158 , pp. 40-46
    • Roemmler, J.1    Kuenkler, M.2    Otto, B.3    Arafat, A.M.4    Bidlingmaier, M.5    Schopohl, J.6
  • 35
  • 36
    • 0034896519 scopus 로고    scopus 로고
    • Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women
    • DOI 10.1016/S8756-3282(01)00487-2, PII S8756328201004872
    • T Thomas B Burguera LJ Melton III EJ Atkinson WM O'Fallon BL Riggs S Khosla 2001 Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women Bone 29 114 120 11502471 10.1016/S8756-3282(01)00487-2 1:CAS:528:DC%2BD3MXlvFWkur4%3D (Pubitemid 32734491)
    • (2001) Bone , vol.29 , Issue.2 , pp. 114-120
    • Thomas, T.1    Burguera, B.2    Melton III, L.J.3    Atkinson, E.J.4    O'Fallon, W.M.5    Riggs, B.L.6    Khosla, S.7
  • 37
    • 33646237558 scopus 로고    scopus 로고
    • Leptin predicts BMD and bone resorption in older women but not older men: The Rancho Bernardo study
    • 16734391 10.1359/jbmr.060206 1:CAS:528:DC%2BD28Xlt1artb0%3D
    • LA Weiss E Barrett-Connor D von Mühlen P Clark 2006 Leptin predicts BMD and bone resorption in older women but not older men: the Rancho Bernardo study J Bone Miner Res 21 758 764 16734391 10.1359/jbmr.060206 1:CAS:528:DC%2BD28Xlt1artb0%3D
    • (2006) J Bone Miner Res , vol.21 , pp. 758-764
    • Weiss, L.A.1    Barrett-Connor, E.2    Von Mühlen, D.3    Clark, P.4
  • 38
    • 33745298324 scopus 로고    scopus 로고
    • Gonadal hormones determine sensitivity to central leptin and insulin
    • DOI 10.2337/diabetes.55.04.06.db05-1339
    • DJ Clegg LM Brown SC Woods SC Benoit 2006 Gonadal hormones determine sensitivity to central leptin and insulin Diabetes 55 978 987 16567519 10.2337/diabetes.55.04.06.db05-1339 1:CAS:528:DC%2BD28XjsVGmtL4%3D (Pubitemid 44100172)
    • (2006) Diabetes , vol.55 , Issue.4 , pp. 978-987
    • Clegg, D.J.1    Brown, L.M.2    Woods, S.C.3    Benoit, S.C.4


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