TLR-4+ peripheral blood monocytes and cardiovascular events in patients with chronic kidney disease - A prospective follow-up study

Nephrology Dialysis Transplantation

Volumn 26, Issue 4, 2011, Pages 1421-1424

  Lorenzen, Johan M ^a   David, Sascha ^a,b   Richter, Alena ^a   De Groot, Kirsten ^a   Kielstein, Jan T ^a   Haller, Hermann ^a   Thum, Thomas ^a   Fliser, Danilo ^c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; C REACTIVE PROTEIN; CD14 ANTIGEN; ERYTHROPOIETIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; RECOMBINANT ERYTHROPOIETIN; TOLL LIKE RECEPTOR 4; TRIACYLGLYCEROL;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ANEMIA; AORTA STENOSIS; ARTICLE; ATHEROGENESIS; BODY MASS; CARDIOVASCULAR DISEASE; CELL POPULATION; CHOLESTEROL BLOOD LEVEL; CHRONIC KIDNEY DISEASE; CORONARY ARTERY BYPASS GRAFT; DIABETES MELLITUS; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HEART INFARCTION; HEMODIALYSIS; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROSPECTIVE STUDY; SMOKING; STROKE; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; FEMALE; FLOW CYTOMETRY; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY FUNCTION TESTS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MONOCYTES; PROGNOSIS; PROSPECTIVE STUDIES; RENAL DIALYSIS; RISK FACTORS; SURVIVAL RATE; TOLL-LIKE RECEPTOR 4;

EID: 79953892220     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfq758     Document Type: Article

References (21)

1. Stirban AO, Tschoepe D. Cardiovascular complications in diabetes: targets and interventions. Diabetes Care 2008; 31: S215-S221
2. Sesso HD, Buring JE, Rifai N et al. C-reactive protein and the risk of developing hypertension. JAMA 2003; 290: 2945-2951 (Pubitemid 37505526)
3. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999; 340: 115-126
4. Pearson TA, Mensah GA, Alexander RWet al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 2003; 107: 499-511 (Pubitemid 36158056)
5. Blake GJ, Rifai N, Buring JE et al. Blood pressure, C-reactive protein, and risk of future cardiovascular events. Circulation 2003; 108: 2993-2999 (Pubitemid 37553568)
6. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352: 1685-1695
7. Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868-874 (Pubitemid 36019640)
8. Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001; 2: 675-680 (Pubitemid 32747155)
9. Janeway CAJr, Medzhitov R. Innate immune recognition. Annu Rev Immunol 2002; 20: 197-216 (Pubitemid 34293424)
10. Edfeldt K, Swedenborg J, Hansson GK et al. Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation 2002; 105: 1158-1161 (Pubitemid 34225814)
11. Reape TJ, Groot PH. Chemokines and atherosclerosis. Atherosclerosis 1999; 147: 213-225 (Pubitemid 29512252)
12. Wyss CA, Neidhart M, Altwegg L et al. Cellular actors, Toll-like receptors, and local cytokine profile in acute coronary syndromes. Eur Heart J 2010; 31: 1457-1469
13. Schoneveld AH, Hoefer I, Sluijter JP et al. Atherosclerotic lesion development and Toll like receptor 2 and 4 responsiveness. Atherosclerosis 2008; 197: 95-104 (Pubitemid 351273277)
14. Foley RN, Parfrey PS, Sarnak MJ. Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis 1998; 32Suppl 3S112-S119 (Pubitemid 28527268)
15. Ritz E. Atherosclerosis in dialyzed patients. Blood Purif 2004; 22: 28-37 (Pubitemid 38142286)
16. Himmelfarb J, Stenvinkel P, Ikizler TA et al. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int 2002; 62: 1524-1538 (Pubitemid 35286260)
17. Wanner C, Krane V, Marz Wet al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 2005; 353: 238-248 (Pubitemid 41058323)
18. Cheung BM, Lauder IJ, Lau CP et al. Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes. Br J Clin Pharmacol 2004; 57: 640-651 (Pubitemid 38582185)
19. Tonelli M, Isles C, Craven T et al. Effect of pravastatin on cardiovascular events in people with chronic kidney disease. Circulation 2004; 110: 1557-1563 (Pubitemid 39297976)
20. Pecoits-Filho R, Lindholm B, Stenvinkel P. The malnutrition, inflammation, and atherosclerosis (MIA) syndrome-the heart of the matter. Nephrol Dial Transplant 2002; 17 Suppl 11, 2831
21. Gueler F, Gwinner W, Schiborr C et al. Biocompatibility parameters of different dialysis membranes assessed during systemic inflammation. Blood Purif 2005; 23: 196-202 (Pubitemid 40874898)