Post-transcriptional regulation of human cathepsin L expression

Biological Chemistry

Volumn 392, Issue 5, 2011, Pages 405-413

  Mittal, Shivani ^a   Mir, Riyaz A ^a   Chauhan, Shyam S ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

5'UTR; bicistronic mRNA; IRES; translation

Indexed keywords

CATHEPSIN L; CATHEPSIN L A; CATHEPSIN L AIII; COMPLEMENTARY DNA; MESSENGER RNA; PLASMID DNA; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ARTICLE; CANCER CELL; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; RETICULOCYTE; TRANSLATION INITIATION;

5' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CATHEPSIN L; CELL LINE; DACTINOMYCIN; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; IMMUNOPRECIPITATION; MICE; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID SYNTHESIS INHIBITORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

ORYCTOLAGUS CUNICULUS;

EID: 79953880269     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2011.039     Document Type: Article

References (47)

1. Ali, N., Pruijn, GJ., Kenan, D.J., Keene, J.D., and Siddiqui, A. (2000). Human La antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation. J. Biol. Chem. 275, 27531-27540.
2. Arora, S. and Chauhan, S.S. (2002). Identification and characterization of a novel human cathepsin L splice variant. Gene 293, 123-131. (Pubitemid 34876468)
3. Bakhshi, R., Goel, A., Seth, P., Chhikara, P., and Chauhan, S.S. (2001). Cloning and characterization of human cathepsin L promoter. Gene 275, 93-101. (Pubitemid 32907330)
4. Borman, A.M., Le Mercier, P., Girard, M., and Kean, K.M. (1997). Comparison of picornaviral IRES-driven internal initiation of translation in cultured cells of different origins. Nucleic Acids Res. 25, 925-932. (Pubitemid 27298259)
5. Chauhan, S.S., Goldstein, L.J., and Gottesman, M.M. (1991). Expression of cathepsin L in human tumors. Cancer Res. 51, 1478-1481.
6. Chauhan, S.S., Popescu, N.C., Ray, D., Fleischmann, R., Gottesman, M.M., and Troen, B.R. (1993). Cloning, genomic organization, and chromosomal localization of human cathepsin L. J. Biol. Chem. 268, 1039-1045. (Pubitemid 23019739)
7. Chauhan, S.S., Ray, D., Kane, S.E., Willingham, M.C., and Gottes-man, M.M. (1998). Involvement of carboxy-terminal amino acids in secretion of human lysosomal protease cathepsin L. Bio-chemistry 37, 8584-8594. (Pubitemid 28275477)
8. Collette, J., Ulku, A.S., Der, CJ., Jones, A., and Erickson, A.H. (2004). Enhanced cathepsin L expression is mediated by differ-ent Ras effector pathways in fibroblasts and epithelial cells. Int. J. Cancer 112, 190-199. (Pubitemid 39244358)
9. Creancier, L., Morello, D., Mercier, P., and Prats, A.C. (2000). Fibroblast growth factor 2 internal ribosome entry site (IRES) activity ex vivo and in transgenic mice reveals a stringent tissue-specific regulation. J. Cell. Biol. 150, 275-281. (Pubitemid 30480243)
10. Dhar, D., Roy, S., and Das, S. (2007). Translational control of the interferon regulatory factor 2 mRNA by IRES element. Nucleic Acids Res. 35, 5409-5421. (Pubitemid 47423915)
11. Fitzgerald, K.D. and Semler, B.L. (2009). Bridging IRES elements in mRNAs to the eukaryotic translation apparatus. Biochim. Bio-phys. Acta 1789, 518-528.
12. Fortenberry, Y.M., Brandal, S., Bialas, R.C., and Church, F.C (2010). Protein C inhibitor regulates both cathepsin L activity and cell-mediated tumour cell migration. Biochim. Biophys. Acta 1800, 580-590.
13. Frade, R., Rodrigues-Lima, F., Huang, S., Xie, K., Guillaume, N., and Bar-Eli, M. (1998). Procathepsin-L, a proteinase that cleaves human C3 (the third component of complement), confers high tumorogenic and metastatic properties to human melanoma cells. Cancer Res. 58, 2733-2736. (Pubitemid 28311900)
14. Frade, R., Rousselet, N., and Jean, D. (2008). Intratumoral gene delivery of anti-cathepsin L single-chain variable fragment by lentiviral vector inhibits tumour progression induced by human melanoma cells. Cancer Gene Ther. 15, 591-604.
15. Gal, S. and Gottesman, M.M. (1988). Isolation and sequence of a cDNA for human pro-(cathepsin L). Biochem. J. 253, 303-306.
16. Gan, W. and Rhoads, R.E. (1996). Internal initiation of translation directed by the 5'untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation. J. Biol. Chem. 271, 623-626.
17. Gocheva, V. and Joyce, J.A. (2007). Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle 6, 60-64. (Pubitemid 46173882)
18. Goulet, B.S.L., Leduy, L., Bogyo, M., Weber, E., Chauhan, S.S., and Nepveu, A. (2007). Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation. Mol. Cancer Res. 5, 899-907. (Pubitemid 47416667)
19. Holcik, M., Graber, T., Lewis, S.M., Lefebvre, C.A., Lacasse, E., and Baird, S. (2005). Spurious splicing within the XIAP 5' UTR occurs in the Rluc/Fluc but not the betagal/CAT bicistronic reporter system. RNA 11, 1605-1609. (Pubitemid 41505533)
20. Hughes, T.A. and Brady, H.J. (2005). Expression of axin2 is regu-lated by the alternative 5'-untranslated regions of its mRNA. J. Biol. Chem. 280, 8581-8588. (Pubitemid 40349762)
21. Iizuka, N., Najita, L., Franzusoff, A., and Sarnow, P. (1994). Cap-dependent and cap-independent translation by internal initiation of mRNAs in cell-free extracts prepared from Saccharomyces cerevisiae. Mol. Cell. Biol. 14, 7322-7330. (Pubitemid 24326397)
22. Jiang, H., Coleman, J., Miskimins, R., Srinivasan, R., and Miski-mins, W.K. (2007). Cap-independent translation through the p27 5'-UTR. Nucleic Acids Res. 35, 4767-4778. (Pubitemid 47250348)
23. Johannes, G. and Sarnow, P. (1998). Cap-independent polysomal association of natural mRNAs encoding c-myc, BiP, and eIF4G conferred by internal ribosome entry sites. RNA 4, 1500-1513. (Pubitemid 28555213)
24. Johannes, G., Carter, M.S., Eisen, M.B., Brown, P.O., and Sarnow, P. (1999). Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray Proc. Natl. Acad. Sci. USA 96, 13118-13123.
25. Kane, S.E. and Gottesman, M.M. (1990). The role of cathepsin L in malignant transformation. Semin. Cancer Biol. 1, 127-136.
26. Katara, R., Mir, R.A., Shukla, A.A., Tiwari, A., Singh, N., and Chauhan, S.S. (2010). Wild type p53-dependent transcriptional upregulation of cathepsin L expression is mediated by C/EBPα in human glioblastoma cells. Biol. Chem. 391, 1031-1040.
27. Keerthivasan, S., Keerthivasan, G., Mittal, S., and Chauhan, S.S. (2007). Transcriptional upregulation of human cathepsin L by VEGF in glioblastoma cells. Gene 399, 129-136. (Pubitemid 47211667)
28. Kos, J. and Lah, T.T. (1998). Cysteine proteinases and their endog-enous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer. Oncol. Rep. 5, 1349-1361. (Pubitemid 28474074)
29. Kozak, M. (1986). Influences of mRNA secondary structure on ini-tiation by eukaryotic ribosomes. Proc. Natl. Acad. Sci. USA 83, 2850-2854. (Pubitemid 16041760)
30. Lankelma, J.M., Voorend, D.M., Barwari, T., Koetsveld, J., Van der Spek, A.H., De Porto, A.P., Van Rooijen, G., and Van Noorden, C.J. (2010). Cathepsin L, target in cancer treatment? Life Sci. 86, 225-233.
31. Mitchell, S.A., Brown, E.C., Coldwell, M.J., Jackson, R.J., and Wil-lis, A.E. (2001). Protein factor requirements of the Apaf-1 inter-nal ribosome entry segment: roles of polypyrimidine tract binding protein and upstream of N-ras. Mol. Cell. Biol. 21, 3364-3374. (Pubitemid 32381772)
32. Payton, S.G., Haska, C.L., Flatley, R.M., Ge, Y., and Matherly, L.H. (2007). Effects of 5' untranslated region diversity on the post-transcriptional regulation of the human reduced folate carrier. Biochim. Biophys. Acta 1769, 131-138. (Pubitemid 46341446)
33. Pesole, G., Liuni, S., Grillo, G., Licciulli, F., Larizza, A., Maka-lowski, W., and Saccone, C. (2000). UTRdb and UTRsite: spe-cialized databases of sequences and functional elements of 5' and 3' untranslated regions ofeukaryotic mRNAs. Nucleic Acids Res. 28, 193-196. (Pubitemid 30047756)
34. Ray, P.S., Grover, R., and Das, S. (2006). Two internal ribosome entry sites mediate the translation of p53 isoforms. EMBO Rep. 7, 404-410.
35. Rescheleit, D.K., Rommerskirch, WJ., and Wiederanders, B. (1996). Sequence analysis and distribution of two new human cathepsin L splice variants. FEBS Lett. 394, 345-348. (Pubitemid 26341471)
36. Rousselet, N, Mills, L., Jean, D., Tellez, C., Bar-Eli, M., and Frade, R. (2004). Inhibition of tumorigenicity and metastasis of human melanoma cells by anti-cathepsin L single chain variable frag-ment. Cancer Res. 64, 146-151. (Pubitemid 38114092)
37. Seth, P., Mahajan, V.S., and Chauhan, S.S. (2003). Transcription of human cathepsin L mRNA species hCATL B from a novel alter-native promoter in the first intron of its gene. Gene 321, 83-91. (Pubitemid 37421398)
38. Shiroki, K., Ohsawa, C., Sugi, N., Wakiyama, M., Miura, K., Wata-nabe, M., Suzuki, Y., and Sugano, S. (2002). Internal ribosome entry site-mediated translation of Smad5 in vivo: requirement for a nuclear event. Nucleic Acids Res. 30, 2851-2861. (Pubitemid 34778145)
39. Stoneley, M., Subkhankulova, T. Le, Quesne, J.P., Coldwell, MJ., Jopling, C.L., Belsham, G.J., and Willis, A.E. (2000). Analysis of the c-myc IRES; a potential role for cell-type specific trans-acting factors and the nuclear compartment. Nucleic Acids Res. 28, 687-694. (Pubitemid 30068251)
40. Teerink, H., Voorma, H.O., and Thomas, A.A.M. (1995). The human insulin like growth factor II leader 1 contains an internal ribo-somal entry site. Biochim. Biophys. Acta 1264, 403-408. (Pubitemid 26016792)
41. Troen, B.R., Ascherman, D., Atlas, D., and Gottesman, M.M. (1988). Cloning and expression of the gene for the major excret-ed protein of transformed mouse fibroblasts. A secreted lysosomal protease regulated by transformation. J. Biol. Chem. 263, 254-261. (Pubitemid 18041072)
42. Urbich, C., Heeschen, C., Aicher, A., Sasaki, K., Bruhl, T., Farhadi, M.R., Vajkoczy, P., Hofmann, W.K., Peters, C., Pennacchio, L.A., et al. (2005). Cathepsin L is required for endothelial pro-genitor cell-induced neovascularization. Nat. Med. 11, 206-213. (Pubitemid 40321357)
43. Vagner, S., Gensac, M.-C., Maret, A., Bayard, F., Amalric, F., Prats, H., and Prats, A.-C. (1995). Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol. Cell. Biol. 15, 35-44. (Pubitemid 24379898)
44. Van Eden, M.E., Byrd, M.P., Sherrill, K.W., and Lloyd, R.E. (2004). Demonstrating internal ribosome entry sites in eukaryotic m-RNAs using stringent RNA test procedures. RNA 10, 720-730. (Pubitemid 38405950)
45. Wang, G., Guo, X., and Floros, J. (2005). Differences in the trans-lation efficiency and mRNA stability mediated by 5'-UTR splice variants of human SP-A1 and SP-A2 genes. Am. J. Physiol. Lung Cell. Mol. Physiol. 289, 497-508.
46. Ye, X., Fong, P., Iizuka, N., Choate, D., and Cavener, D.R. (1997). Ultrabithorax and Antennapedia 5' untranslated regions promote developmentally regulated internal translation initiation. Mol. Cell. Biol. 17, 1714-1721. (Pubitemid 27097400)
47. Zuker, M. (2003). Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31, 3406-3415. (Pubitemid 37442169)