Chronic Q fever: Different serological results in three countries - Results of a follow-up study 6 years after a point source outbreak

Clinical Infectious Diseases

Volumn 52, Issue 8, 2011, Pages 1013-1019

  Healy, Brendan ^a,g   Van Woerden, Hugo ^b   Raoult, Didier ^c   Graves, Stephen ^d   Pitman, James ^e   Lloyd, Graham ^e   Brown, Nigel ^f   Llewelyn, Meirion ^f  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c AIX MARSEILLE UNIVERSITY   (France)

^d GEELONG HOSPITAL   (Australia)

^e PUBLIC HEALTH ENGLAND   (United Kingdom)

^f ROYAL GWENT HOSPITAL   (United Kingdom)

^g PUBLIC HEALTH WALES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANTIBODY TITER; ARTICLE; AUSTRALIA; COHORT ANALYSIS; CONTROLLED STUDY; COXIELLA BURNETII; DIAGNOSTIC ACCURACY; ENDOCARDITIS; EPIDEMIC; FEMALE; FOLLOW UP; FRANCE; HUMAN; IMMUNOFLUORESCENCE; INTERMETHOD COMPARISON; LABORATORY DIAGNOSIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; Q FEVER; SERODIAGNOSIS; SEROLOGY; UNITED KINGDOM;

AUSTRALIA; BACTERIOLOGICAL TECHNIQUES; CHRONIC DISEASE; COXIELLA BURNETII; DISEASE OUTBREAKS; FOLLOW-UP STUDIES; FRANCE; GREAT BRITAIN; HUMANS; IMMUNOASSAY; POLYMERASE CHAIN REACTION; Q FEVER;

EID: 79953876798     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cir132     Document Type: Article

References (29)

1. Maurin M, Raoult D. Q fever. Clin Microbiol Rev 1999; 12:518-53. (Pubitemid 29484745)
2. Dupont HT, Thirion X, Raoult D. Q fever serology determination for microimmunofluorescence. Clin Diagn Lab Immunol 1994; 1:189-96.
3. Ake J, Massung RF, Whitman TJ, Gleeson TD. Difficulties in the diagnosis and management of a US service member presenting with possible chronic Q fever. J Infect 2010; 60:175-7.
4. Fennolar F, Fournier PE, Raoult D. Molecular detection of Coxiella burnetii in the sera of patients with Q fever endocarditis or vascular infection. J Clin Microbiol 2004; 42:4919-24. (Pubitemid 39506189)
5. van Woerden HC, Mason BW, Nehaul LK, et al. Q fever outbreak in industrial setting. Emerg Infect Dis 2004; 10:1282-9. (Pubitemid 38890941)
6. Healy B, Westmoreland D, Lloyd G, Brown N, Llewelyn MB. The value of follow up after acute Q fever Infection. J Infect 2006; 52:e109-112.
7. Graves S, Stenos J, Unsworth N, Nguyen C. Laboratory diagnosis of rickettsial infection. Aust J Med Sci 2006; 27:39-44.
8. Stenos J, Graves S, Lockhart M. Coxiella burnetii. In Schuller M et al. eds., PCR for clinical microbiology: An Australian and international perspective. The Netherlands: Springer, 2010; 145-8.
9. Marmion BP, Storm PA, Ayres JG, et al. Long-term persistence of Coxiella burnetii after acute primary Q fever. Q J Med 2005; 98:7-20.
10. Wilson HG, Neilson GH, Galea EG, Stafford G, O'Brien MF. Q fever endocarditis in Queensland. Circulation 1976; 53:680-4.
11. Moles K, Scott ME, O'Kane H, Connolly JH. Unsuspected Q fever endocarditis - a case report. Ulster Med J 1984; 53:74-5.
12. Boaz IL, Shachar A, Segev S, Weiss P, Rubinstein E. Quiescent Q fever endocarditis exacerbated by cardiac surgery and corticosteroid therapy. Arch Intern Med 1998; 148:1531-2.
13. Willey RF, Matthews MB, Peuthere JF, Marmion BP. Chronic cryptic Q fever infection of the heart. Lancet 1979; 2:270-2. (Pubitemid 9253392)
14. Issartel B, Gauduchon V, Chalabreysse L, et al. Clinically and histo-logically silent Q fever endocarditis accidentally diagnosed by PCR. Clin Microbiol Infect 2002; 8:113-14. (Pubitemid 34993772)
15. Lepidi H, Houpikian P, Liang Z, Raoult D. Cardiac valves in patients with Q fever endocarditis, molecular, and histological studies. J Infect Dis 2003; 187:1097-106. (Pubitemid 36399352)
16. Lovey PV, Morabia A, Bleed D, Peter O, Dupuis G, Petite J. Long term vascular complications of Coxiella burnetii infection in Switzerland: cohort study. BMJ 1999; 319:284-6. (Pubitemid 29353938)
17. Limonard GJ, Nabuurs-Franssen MH, Weers Pothoff G, et al. One year follow up of patients of the ongoing Dutch Q fever outbreak: clinical, serological and echocardiographic findings. Infection 2010; 38:471-7.
18. Soriano F, Camacho MT, Ponte C, Gomez P. Serological differentiation between acute (late control) and endocarditis Q fever. J Clin Pathol 1993; 46:411-14. (Pubitemid 23167413)
19. Dupuis G, Peter O, Luthy R, Nicolet J, Peacock M, Burgdorfer W. Serological diagnosis of Q fever endocarditis. Eur Heart J 1986; 7:1062-6. (Pubitemid 17213035)
20. Raoult D, Urvolgyi J, Etienne J, Roturier M, Puel J, Chaudet H. Diagnosis of endocarditis in acute Q fever by immunofluorescence se-rology. Acta Virol 1988; 32:72-4.
21. Peacock MG, Philip RN, Williams JC, Faulkner RS. Serological evaluation of Q fever in humans: nhanced phase 1 titers of immu-noglobulin G and A are diagnostic for Q fever endocarditis. Infect Immun 1983; 41:1089-98. (Pubitemid 13049287)
22. Worswick D, Marmion BP. Antibody responses in acute and chronic Q fever and in subjects vaccinated against Q fever. J Med Microbiol 1985; 19:281-96. (Pubitemid 15027241)
23. Powell O, Stallman ND. The incidence and significance of Phase 1 complement fixing antibody in Q fever. J Hyg 1962; 60:359-64.
24. Winner SJ, Eglin RP, Moore VI, Mayon-White RT. An outbreak of Q fever affecting postal workers in Oxfordshire. J Infect 1987; 14:255-61. (Pubitemid 17070115)
25. Fournier PE, Casalta JP, Habib G, Messana T, Raoult D. Modification of the diagnostic criteria proposed by the Duke Endocarditis Service to permit improved diagnosis of Q fever endocarditis. Am J Med 1996; 100:629-33. (Pubitemid 26243673)
26. Li JS, Sexton DJ, Mick N, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis 2000; 30:633-8.
27. Hawker JI, Ayres JG, Blair I, et al. A large Q fever outbreak in the West Midlands: wind borne spread into a metropolitan area? Commun Dis Pub Health 1998; 1:180-7.
28. Marmion BP, Sukocheva O, Storm PA, et al. Q fever: persistence of antigenic non viable cell residues of Coxiella burnetii in the host-implications for post Q fever infection fatigue syndrome and other chronic sequelae. QJM 2009; 102:673-84.
29. Sukocheva OA, Marmion BP, Storm PA, Lockhart M, Turra M, Graves S. Long-term persistence after acute Q fever of non-infective Coxiella burnetii cell components, including antigens. QJM 2010; 103:847-63.