Association of hemopexin in tear film and conjunctival macrophages with vernal keratoconjunctivitis

Archives of Ophthalmology

Volumn 129, Issue 4, 2011, Pages 453-461

  Pong, Jeffrey Chiu Fai ^a   Chu, Ching Yan ^b   Li, Wai Ying ^a   Tang, Ling Yin ^b   Li, Lu ^b   Lui, Wai Ting ^b   Poon, Terence Chuen Wai ^b,c   Rao, Srinivas K ^a   Lam, Dennis Shun Chiu ^a   Wang, Chi Chiu ^b,c   Pang, Chi Pui ^a,c  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOPEXIN;

ADOLESCENT; ADULT; ARTICLE; CHEMOSIS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLOGY; EDEMA; ELECTROPHORESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LACRIMAL GLAND; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; SCHOOL CHILD; TEAR FILM; VERNAL CONJUNCTIVITIS;

ADOLESCENT; ANIMALS; CHILD; CONJUNCTIVA; CONJUNCTIVITIS, ALLERGIC; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE PROTEINS; FEMALE; HEMOPEXIN; HUMANS; MACROPHAGES; MALE; MASS SPECTROMETRY; MICE; PROTEOME; TEARS; YOUNG ADULT;

EID: 79953876766     PISSN: 00039950     EISSN: 15383601     Source Type: Journal    
DOI: 10.1001/archophthalmol.2011.41     Document Type: Article

References (28)

1. Uchio E, Kimura R, Migita H, Kozawa M, Kadonosono K. Demographic aspects of allergic ocular diseases and evaluation of new criteria for clinical assessment of ocular allergy. Graefes Arch Clin Exp Ophthalmol. 2008;246(2):291-296. (Pubitemid 351149635)
2. Bremond-Gignac D, Donadieu J, Leonardi A, et al. Prevalence of vernal keratoconjunctivitis: a rare disease? Br J Ophthalmol. 2008;92(8):1097-1102.
3. Bonini S, Bonini S, Lambiase A, et al. Vernal keratoconjunctivitis revisited: a case series of 195 patients with long-term followup. Ophthalmology. 2000;107(6): 1157-1163.
4. Mimura T, Amano S, Funatsu H, et al. Correlations between allergen-specific IgE serum levels in patients with allergic conjunctivitis in spring. Ocul Immunol Inflamm. 2004;12(1):45-51. (Pubitemid 38406452)
5. Cubitt CL, Lausch RN, Oakes JE. Differential regulation of granulocytemacrophage colony-stimulating factor gene expression in human corneal cells by pro-inflammatory cytokines. J Immunol. 1994;153(1):232-240. (Pubitemid 24186536)
6. Allansmith MR, Baird RS, Greiner JV. Vernal conjunctivitis and contact lens- associated giant papillary conjunctivitis compared and contrasted. Am J Ophthalmol. 1979;87(4):544-555. (Pubitemid 9125615)
7. Leonardi A, Borghesan F, Faggian D, Secchi A, Plebani M. Eosinophil cationic protein in tears of normal subjects and patients affected by vernal keratoconjunctivitis. Allergy. 1995;50(7):610-613.
8. Montan PG, van Hage-Hamsten M, Zetterström O. Sustained eosinophil cationic protein release into tears after a single high-dose conjunctival allergen challenge. Clin Exp Allergy. 1996;26(10):1125-1130. (Pubitemid 26354360)
9. Nakajima T, Matsumoto K, Suto H, et al. Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells. Blood. 2001;98(4):1127-1134.
10. Pong JCF, Chu CY, Chu KO, et al. Identification of hemopexin in tear film. Anal Biochem. 2010;404(1):82-85.
11. Chu CY, Poon CW, Pong CF, Pang CP, Wang CC. Human normal tear proteome. Graefes Arch Clin Exp Ophthalmol. 2009;247(6):725-727.
12. Nakamura T, Toda M, Ohbayashi M, Ono SJ. Detailed criteria for the assessment of clinical symptoms in a new murine model of severe allergic conjunctivitis. Cornea. 2003;22(7)(suppl):S13-S18. (Pubitemid 37169600)
13. Poli V. The role of C/EBP isoforms in the control of inflammatory and native immunity functions. J Biol Chem. 1998;273(45):29279-29282. (Pubitemid 28509923)
14. Mauk MR, Rosell FI, Mauk AG. Chromatographically distinguishable heme insertion isoforms of human hemopexin. Biochemistry. 2007;46(51):15033-15041. (Pubitemid 350308895)
15. Rosell FI, Mauk MR, Mauk AG. Effects of metal ion binding on structural dynamics of human hemopexin. Biochemistry. 2007;46(32):9301-9309. (Pubitemid 47255042)
16. Tolosano E, Altruda F. Hemopexin: structure, function, and regulation. DNA Cell Biol. 2002;21(4):297-306. (Pubitemid 34594543)
17. Muller-Eberhard U. Hemopexin. Methods Enzymol. 1988;163:536-565. (Pubitemid 19043445)
18. Smith A, Morgan WT. Transport of heme by hemopexin to the liver: evidence for receptor-mediated uptake. Biochem Biophys Res Commun. 1978;84(1):151-157. (Pubitemid 9015299)
19. Swerts JP, Soula C, Sagot Y, et al. Hemopexin is synthesized in peripheral nerves but not in central nervous system and accumulates after axotomy. J Biol Chem. 1992;267(15):10596-10600.
20. Tolosano E, Cutufia MA, Hirsch E, Silengo L, Altruda F. Specific expression in brain and liver driven by the hemopexin promoter in transgenic mice. Biochem Biophys Res Commun. 1996;218(3):694-703. (Pubitemid 26050725)
21. Chen W, Lu H, Dutt K, Smith A, Hunt DM, Hunt RC. Expression of the protective proteins hemopexin and haptoglobin by cells of the neural retina. Exp Eye Res. 1998;67(1):83-93. (Pubitemid 28364817)
22. Hunt RC, Handy I, Smith A. Heme-mediated reactive oxygen species toxicity to retinal pigment epithelial cells is reduced by hemopexin. J Cell Physiol. 1996; 168(1):81-86. (Pubitemid 26233435)
23. Hunt RC, Hunt DM, Gaur N, Smith A. Hemopexin in the human retina: protection of the retina against heme-mediated toxicity. J Cell Physiol. 1996;168(1):71-80. (Pubitemid 26233434)
24. Weinberg ED. Antibiotic properties and applications of lactoferrin. Curr Pharm Des. 2007;13(8):801-811. (Pubitemid 46585505)
25. Baumann H, Gauldie J. The acute phase response. Immunol Today. 1994;15(2): 74-80. (Pubitemid 24049800)
26. Leonardi A, Curnow SJ, Zhan H, Calder VL. Multiple cytokines in human tear specimens in seasonal and chronic allergic eye disease and in conjunctival fibroblast cultures. Clin Exp Allergy. 2006;36(6):777-784. (Pubitemid 43972973)
27. Uchio E, Ono SY, Ikezawa Z, Ohno S. Tear levels of interferon-γ, interleukin (IL) -2, IL-4 and IL-5 in patients with vernal keratoconjunctivitis, atopic keratoconjunctivitis and allergic conjunctivitis. Clin Exp Allergy. 2000;30(1):103-109. (Pubitemid 30093887)
28. Miyazaki D, Nakamura T, Komatsu N, et al. Roles of chemokines in ocular allergy and possible therapeutic strategies. Cornea. 2004;23(8)(suppl):S48-S54. (Pubitemid 39458544)