Impaired CRH and urocortin expression and function in eutopic endometrium of women with endometriosis

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 4, 2011, Pages 1145-1150

  Novembri, Romina ^a   Borges, Lavinia Estrela ^a   Carrarelli, Patrizia ^a   Rocha, Ana Luiza Lunardi ^a   De Pascalis, Flavio ^a   Florio, Pasquale ^a   Petraglia, Felice ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTALARMIN; ASTRESSIN; CORTICOTROPIN RELEASING FACTOR; ESTRADIOL; MEDROXYPROGESTERONE ACETATE; MESSENGER RNA; PROLACTIN; UROCORTIN;

ADULT; ARTICLE; CONTROLLED STUDY; DECIDUALIZATION; ENDOMETRIOSIS; ENDOMETRIUM BIOPSY; ENDOMETRIUM CELL; ENDOMETRIUM TUMOR; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADULT; CASE-CONTROL STUDIES; CELLS, CULTURED; CORTICOTROPIN-RELEASING HORMONE; DECIDUA; ENDOMETRIOSIS; ENDOMETRIUM; FEMALE; GENE EXPRESSION; HUMANS; MENSTRUAL CYCLE; RNA, MESSENGER; UROCORTINS; UTERINE DISEASES; YOUNG ADULT;

EID: 79953851832     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-2263     Document Type: Article

References (44)

1. Bulun SE 2009 Endometriosis. N Engl J Med 360:268-279
2. Giudice LC 2010 Endometriosis. N Engl J Med 362:2389-2398
3. Ulukus M, Cakmak H, Arici A 2006 The role of endometrium in endometriosis. J Soc Gynecol Investig 13:467-476 (Pubitemid 44528303)
4. Dey SK, Lim H, Das SK, Reese J, Paria BC, Daikoku T, Wang H 2004 Molecular cues to implantation. Endocr Rev 25:341-373 (Pubitemid 38780665)
5. Burney RO, Talbi S, Hamilton AE, Vo KC, Nyegaard M, Nezhat CR, Lessey BA, Giudice LC 2007 Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology 148: 3814-3826 (Pubitemid 47105847)
6. Klemmt PA, Carver JG, Kennedy SH, Koninckx PR, Mardon HJ 2006 Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril 85:564-572 (Pubitemid 43261544)
7. Minici F, Tiberi F, Tropea A, Orlando M, Gangale MF, Romani F, Campo S, Bompiani A, Lanzone A, Apa R 2008 Endometriosis and human infertility: A new investigation into the role of eutopic endometrium. Hum Reprod 23:530-537 (Pubitemid 351651209)
8. Lessey BA, Castelbaum AJ, Sawin SW, Buck CA, Schinnar R, Bilker W,StromBL1994 Aberrant integrin expression in the endometrium of women with endometriosis. J Clin Endocrinol Metab 79:643-649 (Pubitemid 24256567)
9. Noble LS, Simpson ER, Johns A, Bulun SE 1996 Aromatase expression in endometriosis. J Clin Endocrinol Metab 81:174-179 (Pubitemid 26035021)
10. Burney RO, Hamilton AE, Aghajanova L, Vo KC, Nezhat CN, Lessey BA, Giudice LC 2009 MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis. Mol Hum Reprod 15:625-631
11. Aghajanova L, Hamilton A, Kwintkiewicz J, Vo KC, Giudice LC 2009 Steroidogenic enzyme and key decidualization marker dysregulation in endometrial stromal cells from women with versus without endometriosis. Biol Reprod 80:105-114
12. Petraglia F, Tabanelli S, Galassi MC, Garuti GC, Mancini AC, Genazzani AR, Gurpide E 1992 Human decidua and in vitro decidualized endometrial stromal cells at term contain immunoreactive corticotropin-releasing factor (CRF) and CRF messenger ribonucleic acid. J Clin Endocrinol Metab 74:1427-1431
13. Florio P, Arcuri F, Ciarmela P, Runci Y, Romagnoli R, Cintorino M, Di Blasio AM, Petraglia F 2002 Identification of urocortin mRNA and peptide in the human endometrium. J Endocrinol 173:R9-R14 (Pubitemid 34552468)
14. Mastorakos G, Scopa CD, Kao LC, Vryonidou A, Friedman TC, Kattis D, Phenekos C, Rabin D, Chrousos GP 1996 Presence of immunoreactive corticotropin-releasing hormone in human endometrium. J Clin Endocrinol Metab 81:1046-1050 (Pubitemid 26083970)
15. Di Blasio AM, Pecori Giraldi F, Viganò P, Petraglia F, Vignali M, Cavagnini F 1997 Expression of corticotropin-releasing hormone and its R1 receptor in human endometrial stromal cells. J Clin Endocrinol Metab 82:1594-1597 (Pubitemid 27200440)
16. Ferrari A, Petraglia F, GurpideE1995 Corticotropin releasing factor decidualizes human endometrial stromal cells in vitro. Interaction with progestins. J Steroid Biochem Mol Biol 54:251-255
17. Torricelli M, De Falco G, Florio P, Rossi M, Leucci E, Viganò P, Leoncini L, Petraglia F 2007 Secretory endometrium highly expresses urocortin messenger RNA and peptide: Possible role in the decidualization process. Hum Reprod 22:92-96 (Pubitemid 44942670)
18. Karteris E, Papadopoulou N, Grammatopoulos DK, Hillhouse EW 2004 Expression and signalling characteristics of the corticotrophin-releasing hormone receptors during the implantation phase in the human endometrium. J Mol Endocrinol 32:21-32 (Pubitemid 38312619)
19. Karalis K, Sano H, Redwine J, Listwak S, Wilder RL, Chrousos GP 1991 Autocrine or paracrine inflammatory actions of corticotropinreleasing hormone in vivo. Science 18; 254:421-423 (Pubitemid 21917357)
20. Gravanis A, Margioris AN 2005 The corticotropin-releasing factor (CRF) family of neuropeptides in inflammation: Potential therapeutic applications. Curr Med Chem 12:1503-1512 (Pubitemid 40872575)
21. Florio P, Busacca M, Vignali M, Viganò P, Woods RJ, Lowry PJ, Genazzani AR, Luisi S, Santuz M, Petraglia F 1998 Peritoneal fluid levels of immunoreactive corticotropin-releasing factor (CRF) and CRF-binding protein (CRF-BP) in healthy and endometriosic women. J Endocrinol Invest 21:37-42 (Pubitemid 28142625)
22. Florio P, Reis FM, Torres PB, Calonaci F, Toti P, Bocchi C, Linton EA, Petraglia F 2007 Plasma urocortin levels in the diagnosis of ovarian endometriosis. Obstet Gynecol 110:594-600 (Pubitemid 47359583)
23. Kempuraj D, Papadopoulou N, Stanford EJ, Christodoulou S, Madhappan B, Sant GR, Solage K, Adams T, Theoharides TC 2004 Increased numbers of activated mast cells in endometriosis lesions positive for corticotropin releasing hormone and urocortin. Am J Reprod Immunol 52:267-275 (Pubitemid 39462197)
24. Brosens IA, Cornillie F, Koninckx P, Vásquez G 1985 Evolution of the Revised American Fertility Society Classification of Endometriosis. Fertil Steril 44:714-716
25. Severi FM, Bocchi C, Florio P, Cobellis L, Ignacchiti E, Petraglia F 2003 Transvaginal ultrasonography in women receiving emergency contraception. Fertil Steril 79:1074-1077 (Pubitemid 36547841)
26. Noyes RW, Hertig AT, Rock J 1975 Dating the endometrial biopsy. Am J Obstet Gynecol 122:262-263
27. Livak KJ, Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) method. Methods 25:402-408 (Pubitemid 34164012)
28. Makrigiannakis A, Margioris AN, Chatzaki E, Zoumakis E, Chrousos GP, Gravanis A 1999 The decidualizing effect of progesterone may involve direct transcriptional activation of corticotrophin-releasing hormone from human endometrial stromal cells. Mol Hum Reprod 5:789-796 (Pubitemid 29406740)
29. Bulun SE, Cheng YH, Yin P, Imir G, Utsunomiya H, Attar E, Innes J, Kim JJ 2006 Progesterone resistance in endometriosis: Link to failure to metabolize estradiol. Mol Cell Endocrinol 248:94-103
30. PerrinMH,ValeWW1999 Corticotropin releasing factor receptors and their ligand family. Ann NY Acad Sci 885:312-328
31. Hermus AR, Pieters GF, Willemsen JJ, Ross HA, Smals AG, Benraad TJ, KloppenborgPW1987 Hypotensive effects of ovine and human corticotrophin- releasing factors in man. Eur J Clin Pharmacol 31: 531-534 (Pubitemid 17016931)
32. Kempuraj D, Papadopoulou NG, Lytinas M, Huang M, Kandere-Grzybowska K, Madhappan B, Boucher W, Christodoulou S, Athanassiou A, Theoharides TC 2004 Corticotropin-releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells. Endocrinology 145:43-48 (Pubitemid 38094499)
33. Stephanou A, Jessop DS, Knight RA, Lightman SL 1990 Corticotrophin- releasing factor-like immunoreactivity and mRNA in human leukocytes. Brain Behav Immun 4:67-73 (Pubitemid 20196454)
34. Tanaka K, Minoura H, Isobe T, Yonaha H, Kawato H, Wang DF, Yoshida T, Kojima M, Kangawa K, Toyoda N 2003 Ghrelin is involved in the decidualization of human endometrial stromal cells. J Clin Endocrinol Metab 88:2335-2340 (Pubitemid 36549915)
35. Vittoria A, Paino G, La Mura E, Budetta G, Cecio A 1989 Chromogranin-and somatostatin-containing neuroendocrine cells in the porcine uterus. An immunocytochemical study. Anat Histol Embryol 18:136-142
36. Wang G, Tokushige N, Russell P, Dubinovsky S, Markham R, Fraser IS 2010 Neuroendocrine cells in eutopic endometrium of women with endometriosis. Hum Reprod 25:387-391
37. Al-Jefout M, Dezarnaulds G, Cooper M, Tokushige N, Luscombe GM, Markham R, Fraser IS 2009 Diagnosis of endometriosis by detection of nerve fibres in an endometrial biopsy: A double blind study. Hum Reprod 24:3019-3024
38. Athanassakis I, Farmakiotis V, Aifantis I, Gravanis A, Vassiliadis S 1999 Expression of corticotrophin-releasing hormone in the mouse uterus: Participation in embryo implantation. J Endocrinol 163: 221-217
39. Makrigiannakis A, Zoumakis E, Kalantaridou S, Coutifaris C, Margioris AN, Coukos G, Rice KC, Gravanis A, Chrousos GP 2001 Corticotropin-releasing hormone promotes blastocyst implantation and early maternal tolerance. Nat Immunol 2:1018-1024 (Pubitemid 33069496)
40. Kalantaridou SN, Makrigiannakis A, Zoumakis E, Chrousos GP 2004 Reproductive functions of corticotropin-releasing hormone. Research and potential clinical utility of antalarmins (CRH receptor type 1 antagonists). Am J Reprod Immunol 51:269-274 (Pubitemid 38455728)
41. Zoumakis E, Margioris AN, Stournaras C, Dermitzaki E, Angelakis E, Makrigiannakis A, Koumantakis E, Gravanis A 2000 Corticotrophin-releasing hormone (CRH) interacts with inflammatory prostaglandins and interleukins and affects the decidualization of human endometrial stroma. Mol Hum Reprod 6:344-351 (Pubitemid 30171522)
42. Jabbour HN, Kelly RW, Fraser HM, CritchleyHO2006 Endocrine regulation of menstruation. Endocr Rev 27:17-46 (Pubitemid 43228237)
43. Tran LV, Tokushige N, Berbic M, Markham R, Fraser IS 2009 Macrophages and nerve fibres in peritoneal endometriosis. Hum Reprod 24:835-841
44. Kalantaridou SN, Zoumakis E, Weil S, Lavasidis LG, Chrousos GP, Makrigiannakis A 2007 Reproductive corticotropin releasing hormone, implantation, and fetal immunotolerance. Crit Rev Clin Lab Sci 44:461-481 (Pubitemid 47619400)