Beta-adrenergic modulation of heart rate: Contribution of the slow delayed rectifier K+ current (IKs)

Computing in Cardiology

Volumn 37, Issue , 2010, Pages 629-631

  Wilders, Ronald ^a   Hoekstra, Maaike ^a   Van Ginneken, Antoni C G ^a   Verkerk, A O ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MODEL; CYCLE LENGTH; DELAYED RECTIFIER; EXPERIMENTAL DATA; HEART RATES; HYPERPOLARIZATION; POTASSIUM CURRENTS; RABBIT SA NODE;

CARDIOLOGY; COMPUTER SIMULATION; MATHEMATICAL MODELS; MODULATION; PACEMAKERS; POTASSIUM;

ELECTRIC RECTIFIERS;

EID: 79953824752     PISSN: 23258861     EISSN: 2325887X     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (5)

1. Lei M, Cooper PJ, Camelliti P, Kohl P. Role of the 293bsensitive, slowly activating delayed rectifier potassium current, iK,s, in pacemaker activity of rabbit isolated sinoatrial node cells. Cardiovasc Res 2002;53:68-79. (Pubitemid 34020767)
2. Kurata Y, Hisatome I, Imanishi S, Shibamoto T. Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell. Am J Physiol Heart Circ Physiol 2002;283:H2074-101. (Pubitemid 35217043)
3. K,s in rabbit sinoatrial node cells. J Physiol 2001;535:703-14. (Pubitemid 32894483)
4. Verkerk AO, van Ginneken ACG, Wilders R. Role of the slow component of the delayed rectifier K+ current in sinoatrial node pacemaker activity. Heart Rhythm 2010;5(Suppl 1):S224.
5. Hoekstra M, Verkerk AO, van Ginneken ACG, Wilders R. HCN4 current during human sinoatrial node action potentials. Heart Rhythm 2010;5(Suppl 1):S410.