Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease

Intensive Care Medicine

Volumn 37, Issue 3, 2011, Pages 502-509

  Fraisse, Alain ^a   Butrous, Ghazwan ^b,d   Taylor, Mary B ^c   Oakes, Michael ^d   Dilleen, Maria ^d   Wessel, David L ^e  

^a TIMONE HOSPITAL   (France)

^b UNIVERSITY OF KENT   (United Kingdom)

^c MONROE CARELL JR CHILDREN S HOSPITAL AT VANDERBILT   (United States)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^e CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Congenital heart disease; Postoperative management; Pulmonary arterial hypertension; Pulmonary vasodilatation

Indexed keywords

LACTIC ACID; NITRIC OXIDE; PLACEBO; SILDENAFIL;

ADOLESCENT; ARTICLE; BOLUS INJECTION; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONGENITAL HEART DISEASE; CONTINUOUS INFUSION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; DRUG SAFETY; ECHOCARDIOGRAPHY; FEMALE; HUMAN; HYPOTENSION; INFANT; INTENSIVE CARE UNIT; LACTATE BLOOD LEVEL; LENGTH OF STAY; LOW DRUG DOSE; LUNG ARTERY PRESSURE; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PULMONARY HYPERTENSION; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SYSTOLIC BLOOD PRESSURE; SYSTOLIC LUNG ARTERY PRESSURE; TREATMENT DURATION;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOXICITY; FEMALE; HEART DEFECTS, CONGENITAL; HUMANS; HYPERTENSION, PULMONARY; INFANT; INFUSIONS, INTRAVENOUS; MALE; PIPERAZINES; POSTOPERATIVE COMPLICATIONS; PURINES; SULFONES; VASODILATION; VASODILATOR AGENTS;

EID: 79953819648     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-010-2065-4     Document Type: Article

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