New effective treatment regimen for children infected with a double-resistant Helicobacter pylori strain

Journal of Pediatric Gastroenterology and Nutrition

Volumn 52, Issue 4, 2011, Pages 424-428

  Schwarzer, A ^a   Urruzuno, P ^b   Iwanczak B ^c   Martinez Gomez M Z ^d   Kalach, N ^e   Roma Giannikou, E ^f   Liptay, S ^g   Bontem, P ^h   Buderus, S ⁱ   Wenzl, T G ^j   Koletzko, S ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^c UNIVERSITY OF WROC AW   (Poland)

^d HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

^e UNIVERSITÉ CATHOLIQUE DE LILLE   (France)

^f UNIVERSITY OF ATHENS   (Greece)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^h HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

ⁱ ST MARIEN HOSPITAL   (Germany)

^j UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

more..

Author keywords

children; clarithromycin; double resistance; Helicobacter pylori; metronidazole

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; ESOMEPRAZOLE; METRONIDAZOLE;

ABDOMINAL PAIN; ADOLESCENT; ANTIBIOTIC RESISTANCE; ARTICLE; CHILD; DIARRHEA; DRY SKIN; ERADICATION THERAPY; FEMALE; HEADACHE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PRIORITY JOURNAL; PRURITUS; UREA BREATH TEST; VOMITING;

HELICOBACTER PYLORI;

EID: 79953816807     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e3181fc8c58     Document Type: Article

References (36)

1. Malfertheiner P, Megraud F, O'Morain C, et al. Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut 2007;56:772-81. (Pubitemid 46854190)
2. Jones NL, Sherman P, Fallone CA, et al. Canadian Helicobacter Study Group Consensus Conference: update on the approach to Helicobacter pylori infection in children and adolescents: an evidence-based evaluation. Can J Gastroenterol 2005;19:399-408. (Pubitemid 41149881)
3. Drumm B, Koletzko S, Oderda G. Helicobacter pylori infection in children: a consensus statement. J Pediatr Gastroenterol Nutr 2000;30:207-13. (Pubitemid 30366200)
4. Gold B, Colletti RB, Abbott M, et al. The North American Society for Pediatric Gastroenterology and Nutrition. Helicobacter pylori infection in children: recommendations for diagnosis and treatment. J Pediatr Gastroenterol Nutr 2000;31:490-7.
5. Fock KM, Katelaris P, Sugano K, et al. Second Asia-Pacific Consensus Guidelines for Helicobacter pylori infection. J Gastroenterol Hepatol 2009;24:1587-600.
6. Bontems P, Devaster JM, Corvaglia L, et al. Twelve year observation of primary and secondary antibiotic-resistant Helicobacter pylori strains in children. Pediatr Infect Dis J 2001;20:1033-8. (Pubitemid 33055073)
7. Dupont C, Kalach N, Raymond J. Helicobacter pylori and antimicrobial susceptibility in children. J Pediatr Gastroenterol Nutr 2003;36:311-3. (Pubitemid 39274601)
8. Crone J, Granditsch G, Huber WD, et al. Helicobacter pylori in children and adolescents: increase of primary clarithromycin resistance, 1997-2000. J Pediatr Gastroenterol Nutr 2003;36:368-71.
9. Alarcon T, Vega AE, Domingo D, et al. Clarithromycin resistance among Helicobacter pylori strains isolated from children: prevalence and study of mechanism of resistance by PCR-restriction fragment length polymorphism analysis. J Clin Microbiol 2003;41:486-99.
10. Boyanova L, Gergova G, Nikolov R, et al. Prevalence and evolution of Helicobacter pylori resistance to 6 antibacterial agents over 12 years and correlation between susceptibility testing methods. Diagn Microbiol Infect Dis 2008;60:409-15. (Pubitemid 351380781)
11. Megraud F. Helicobacter pylori and antibiotic resistance. Gut 2007;56:1502. (Pubitemid 350033185)
12. Chisholm SA, Teare EL, Davies K, et al. Surveillance of primary antibiotic resistance of Helicobacter pylori at centres in England and Wales over a six-year period (2000-2005). Eur Surveill 2007;12:E3-4.
13. Kalach N, Benhamou PH, Campeotto F, et al. Clarithromycin resistance and bacterial eradication of Helicobacter pylori in children. Antimicrob Agents Chemother 2001;45:2134-5. (Pubitemid 32591712)
14. Gisbert JP, Calvet X, O'Connor JP, et al. The sequential therapy regimen for Helicobacter pylori eradication. Expert Opin Pharmacother 2010;11:905-18.
15. Filipec KT, Katicic M, Skurla B, et al. Helicobacter pylori eradication therapy success regarding different treatment period based on clarithromycin or metronidazole triple-therapy regimens. Helicobacter 2009;14:29-35.
16. Pohle T, Stoll R, Kirchner T, et al. Eradication of Helicobacter pylori with lansoprazole, roxithromycin and metronidazole: an open pilot study. Aliment Pharmacol Ther 1998;12:1273-8. (Pubitemid 28565970)
17. Bardhan K, Bayerdorffer E, Veldhuyzen-Van-Zanten SJ, et al. The HOMER Study: the effect of increasing the dose of metronidazole when given with omeprazole and amoxicillin to cure Helicobacter pylori infection. Helicobacter 2000;5:196-201. (Pubitemid 34948000)
18. Gisbert JP, Calvet X, O'Connor A, et al. Sequential therapy for Helicobacter pylori eradication: a critical review. J Clin Gastroenterol 2010;44:313-25.
19. Koletzko S, Richy F, Bontems P, et al. Prospective multicenter study on antibiotic resistance of Helicobacter pylori strains obtained from children living in Europe. Gut 2006;55:1711-6. (Pubitemid 44893567)
20. 13C-urea breath test results in children. J Pediatr Gastroenterol Nutr 2000;30:85-91.
21. Miehlke S, Kirsch C, Schneider-Brachert W, et al. A prospective, randomized study of quadruple therapy and high-dose dual therapy for treatment of Helicobacter pylori resistant to both metronidazole and clarithromycin. Helicobacter 2003;8:310-9. (Pubitemid 37093017)
22. Miehlke S, Schneider-BrachertW, Kirsch C, et al. One-week once-daily triple therapy with esomeprazole, moxifloxacin, and rifabutin for eradication of persistent Helicobacter pylori resistant to both metronidazole and clarithromycin. Helicobacter 2008;13:69-74.
23. Gisbert JP, Perez-Aisa A, Castro-Fernandez M, et al. Helicobacter pylori first-line treatment and rescue option containing levofloxacin in patients allergic to penicillin. Dig Liver Dis 2010;42:287-90.
24. Gatta L, Vakil N, Leandro G, et al. Sequential therapy or triple therapy for Helicobacter pylori infection: systematic review and meta-analysis of randomized controlled trials in adults and children. Am J Gastroenterol 2009;104:3069-79.
25. Qasim A, O'Morain CA, O'Connor HJ. Helicobacter pylori eradication: role of individual therapy constituents and therapy duration. Fundam Clin Pharmacol 2009;23:43-52.
26. Arenz T, Antos D, Russmann H, et al. Esomeprazole-based 1-week triple therapy directed by susceptibility testing for eradication of Helicobacter pylori infection in children. J Pediatr Gastroenterol Nutr 2006;43:180-4. (Pubitemid 44180501)
27. Choi IJ, Jung HC, Choi KW, et al. Efficacy of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy for Helicobacter pylori eradication. Aliment Pharmacol Ther 2002;16:145-51. (Pubitemid 34123875)
28. Oderda G, Rapa A, Bona G. A systematic review of Helicobacter pylori eradication treatment schedules in children. Aliment Pharmacol Ther 2000;14(Suppl 3):59-66.
29. Oderda G, Marinello D, Lerro P, et al. Dual vs. triple therapy for childhood Helicobacter pylori gastritis: a double-blind randomized multicentre trial. Helicobacter 2004;9:293-301. (Pubitemid 38988329)
30. Tindberg Y, Blennow M, Granstrom M. Clinical symptoms and social factors in a cohort of children spontaneously clearing Helicobacter pylori infection. Acta Paediatr 1999;88:631-5. (Pubitemid 29302651)
31. Lofmark S, Edlund C, Nord CE. Metronidazole is still the drug of choice for treatment of anaerobic infections. Clin Infect Dis 2010;50 (Suppl 1):S16-23.
32. Behrens R, Lang T, Keller KM, et al. Dual versus triple therapy of Helicobacter pylori infection: results of a multicentre trial. Arch Dis Child 1999;81:68-70. (Pubitemid 29307461)
33. Raucy JL, Allen SW. Recent advances in P450 research. Pharmacogenomics J 2001;1:178-86. (Pubitemid 33756657)
34. Andersson T, Hassall E, Lundborg P, et al. Pharmacokinetics of orally administered omeprazole in children. International Pediatric Omeprazole Pharmacokinetic Group. Am J Gastroenterol 2000;95:3101-6.
35. Paoluzi P, Iacopini F, Crispino P, et al. 2-week triple therapy for Helicobacter pylori infection is better than 1-week in clinical practice: a large prospective single-center randomized study. Helicobacter 2006;11:562-8. (Pubitemid 44674141)
36. Khurana R, Fischbach L, Chiba N, et al. Meta-analysis: Helicobacter pylori eradication treatment efficacy in children. Aliment Pharmacol Ther 2007;25:523-36.