Immune synapses: Mitochondrial morphology matters

EMBO Journal

Volumn 30, Issue 7, 2011, Pages 1187-1189

  Junker, Christian ^a   Hoth, Markus ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DYNAMIN RELATED PROTEIN 1; MITOCHONDRIAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRUCTURE; IMMUNOLOGICAL SYNAPSE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL;

GTP PHOSPHOHYDROLASES; HUMANS; IMMUNOLOGICAL SYNAPSES; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS;

EID: 79953802078     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.72     Document Type: Article

References (13)

1. Baixauli F, Mart́n-Cófreces NB, Morlino G, Carrasco YR, Calabia-Linares C, Veiga E, Serrador JM, Sánchez-Madrid F (2011) The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signaling at the immune synapse. EMBO J30: 1238-1250
2. Bleazard W, McCaffery JM, King EJ, Bale S, Mozdy A, Tieu Q, Nunnari J, Shaw JM (1999) The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat Cell Biol 1: 298-304 (Pubitemid 129495781)
3. Chan DC (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125: 1241-1252 (Pubitemid 43929096)
4. Contento RL, Campello S, Trovato AE, Magrini E, Anselmi F, Viola A (2010) Adhesion shapes T cells for prompt and sustained T-cell receptor signalling. EMBO J29: 4035-4047
5. de Brito OM, Scorrano L (2008) Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456: 605-610
6. Hollenbeck PJ, Saxton WM (2005) The axonal transport of mito-chondria. J Cell Sci 118 (Part 23): 5411-5419
7. Kummerow C, Junker C, Kruse K, Rieger H, Quintana A, Hoth M (2009) The immunological synapse controls local and global calcium signals in T lymphocytes. Immunol Rev 231: 132-147
8. Lee KH, Dinner AR, Tu C, Campi G, Raychaudhuri S, Varma R, Sims TN, Burack WR, Wu H, Wang J, Kanagawa O, Markiewicz M, Allen PM, Dustin ML, Chakraborty AK, Shaw AS (2003) The immunological synapse balances T cell receptor signaling and degradation. Science 302: 1218-1222 (Pubitemid 37421028)
9. Li Z, Okamoto K, Hayashi Y, Sheng M (2004) The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119: 873-887 (Pubitemid 40017692)
10. Quintana A, Schwindling C, Wenning AS, Becherer U, Rettig J, Schwarz EC, Hoth M (2007) T cell activation requires mitochon-drial translocation to the immunological synapse. Proc Natl Acad Sci USA 104: 14418-14423 (Pubitemid 350003276)
11. Romanello V, Guadagnin E, Gomes L, Roder I, Sandri C, Petersen Y Milan G, Masiero E, Del Piccolo P, Foretz M, Scorrano L, Rudolf R, Sandri M (2010) Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J 29: 1774-1785
12. Singaravelu K, Nelson C, Bakowski D, Martins de Brito O, Ng SW, Di Capite J, Powell T, Scorrano L, Parekh AB (2011) Mitofusin 2 regulates STIM1 migration from the Ca2+ store to the plasma membrane in cells with depolarised mitochondria. J Biol Chem (advance online publication; doi:10.1074/jbc.M110. 174029)
13. Wang X, Schwarz TL (2009) The mechanism of Ca2+-dependent regulation of kinesin-mediated mitochondrial motility Cell 136: 163-174