Antioxidant content and ultraviolet absorption characteristics of human tears

Optometry and Vision Science

Volumn 88, Issue 4, 2011, Pages 507-511

  Choy, Camus Kar Man ^a   Cho, Pauline ^a   Benzie, Iris F F ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

aging eye; Antioxidant; artificial tears; dry eye syndrome; human tears; UV light

Indexed keywords

AGING EYE; ANTIOXIDANT; ARTIFICIAL TEARS; DRY EYE; HUMAN TEARS; UV LIGHT;

ABSORPTION; CURING; RADIATION PROTECTION; SINGLE CRYSTALS;

EYE PROTECTION;

ANTIOXIDANT; EYE DROPS;

ABSORPTION; ADULT; AGED; AGING; ARTICLE; CHEMISTRY; CORNEA; DRY EYE; HUMAN; LACRIMAL FLUID; METABOLISM; MIDDLE AGED; PHYSIOLOGY; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ABSORPTION; ADULT; AGED; AGING; ANTIOXIDANTS; CORNEA; DRY EYE SYNDROMES; HUMANS; MIDDLE AGED; OPHTHALMIC SOLUTIONS; TEARS; ULTRAVIOLET RAYS; YOUNG ADULT;

EID: 79953797684     PISSN: 10405488     EISSN: None     Source Type: Journal    
DOI: 10.1097/OPX.0b013e31820e9fe2     Document Type: Article

References (47)

1. Schein OD, Munoz B, Tielsch JM, Bandeen-Roche K, West S. Prevalence of dry eye among the elderly. Am J Ophthalmol 1997;124: 723-8. (Pubitemid 27523148)
2. Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Prevalence of dry eye syndrome among US women. Am J Ophthalmol 2003;136: 318-26. (Pubitemid 36904081)
3. Schaumberg DA, Dana R, Buring JE, Sullivan DA. Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies. Arch Ophthalmol 2009;127:763-8.
4. Lin PY, Tsai SY, Cheng CY, Liu JH, Chou P, Hsu WM. Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study. Ophthalmology 2003;110:1096-101. (Pubitemid 36676639)
5. Management and therapy of dry eye disease: report of the Management and Therapy Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 2007;5:163-78.
6. Methodologies to diagnose and monitor dry eye disease: report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 2007;5:108-52.
7. Terry MA. Dry eye in the elderly. Drugs Aging 2001;18:101-7.
8. Augustin AJ, Spitznas M, Kaviani N, Meller D, Koch FH, Grus F, Gobbels MJ. Oxidative reactions in the tear fluid of patients suffering from dry eyes. Graefes Arch Clin Exp Ophthalmol 1995;233:694-8.
9. Nakamura S, Shibuya M, Nakashima H, Hisamura R, Masuda N, Imagawa T, Uehara M, Tsubota K. Involvement of oxidative stress on corneal epithelial alterations in a blink-suppressed dry eye. Invest Ophthalmol Vis Sci 2007;48:1552-8. (Pubitemid 351261338)
10. Shimmura S, Suematsu M, Shimoyama M, Tsubota K, Oguchi Y, Ishimura Y. Subthreshold UV radiation-induced peroxide formation in cultured corneal epithelial cells: the protective effects of lactoferrin. Exp Eye Res 1996;63:519-26. (Pubitemid 26420793)
11. Ohashi Y, Ishida R, Kojima T, Goto E, Matsumoto Y, Watanabe K, Ishida N, Nakata K, Takeuchi T, Tsubota K. Abnormal protein profiles in tears with dry eye syndrome. Am J Ophthalmol 2003;136: 291-9. (Pubitemid 36904077)
12. Draper CE, Adeghate EA, Singh J, Pallot DJ. Evidence to suggest morphological and physiological alterations of lacrimal gland acini with ageing. Exp Eye Res 1999;68:265-76. (Pubitemid 29130715)
13. Cejkova J, Ardan T, Cejka C, Malec J, Jirsova K, Filipec M, Ruzickova E, Dotrelova D, Brunova B. Ocular surface injuries in autoimmune dry eye. The severity of microscopical disturbances goes parallel with the severity of symptoms of dryness. Histol Histopathol 2009;24:1357-65.
14. Goto E, Yagi Y, Matsumoto Y, Tsubota K. Impaired functional visual acuity of dry eye patients. Am J Ophthalmol 2002;133:181-6. (Pubitemid 34072045)
15. Miljanovic B, Dana R, Sullivan DA, Schaumberg DA. Impact of dry eye syndrome on vision-related quality of life. Am J Ophthalmol 2007;143:409-15.
16. Simmons PA, Vehige JG. Clinical performance of a mid-viscosity artificial tear for dry eye treatment. Cornea 2007;26:294-302. (Pubitemid 46568829)
17. Tsubota K, Satake Y, Shimazaki J. Treatment of severe dry eye. Lancet 1996;348:123.
18. Albietz JM. Dry eye: an update on clinical diagnosis, management and promising new treatments. Clin Exp Optom 2001;84:4-18. (Pubitemid 33274911)
19. Choy EP, Cho P, Benzie IF, Choy CK. Investigation of corneal effect of different types of artificial tears in a simulated dry eye condition using a novel porcine dry eye model (pDEM). Cornea 2006;25: 1200-4. (Pubitemid 46005860)
20. Asbell PA. Increasing importance of dry eye syndrome and the ideal artificial tear: consensus views from a roundtable discussion. Curr Med Res Opin 2006;22:2149-57. (Pubitemid 44789979)
21. Craig JP. A natural solution to dry eye? Clin Experiment Ophthalmol 2008;36:109-10. (Pubitemid 351445140)
22. Choy CK, Cho P, Benzie IFF. Antioxidants in human tears; do they originate from corneal leakage or from lacrimal gland secretion? Clin Exp Optom 2004;87:24-7.
23. Callender M, Morrison PE. A quantitative study of human tear proteins before and after adaption to non-flexible contact lenses. Am J Optom Physiol Opt 1974;51:939-45.
24. Choy CK, Cho P, Chung WY, Benzie IF. Water-soluble antioxidants in human tears: effect of the collection method. Invest Ophthalmol Vis Sci 2001;42:3130-4. (Pubitemid 33740670)
25. Fullard RJ, Snyder C. Protein levels in nonstimulated and stimulated tears of normal human subjects. Invest Ophthalmol Vis Sci 1990;31: 1119-26. (Pubitemid 20197636)
26. Choy CK, Benzie IF, Cho P. Ascorbic acid concentration and total antioxidant activity of human tear fluid measured using the FRASC assay. Invest Ophthalmol Vis Sci 2000;41:3293-8.
27. Benzie IF, Strain JJ. Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol 1999;299:15-27. (Pubitemid 28483878)
28. Choy C, Benzie I, Cho P. Antioxidants in tears and plasma: interrelationships and effect of vitamin C supplementation. Curr Eye Res 2003;27:55-60. (Pubitemid 36936347)
29. Choy CK, Cho P, Chung WY, Benzie IF. Reflex tear ascorbate in Hong Kong Chinese subjects: method comparison and biological variation. Optom Vis Sci 2003;80:632-6. (Pubitemid 37174323)
30. Hurwitz JJ, ed. In: The Lacrimal System. Philadelphia, PA: Lippincott- Raven Press; 1996.
31. Jordan A, Baum J. Basic tear flow. Does it exist? Ophthalmology 1980;87:920-30. (Pubitemid 11212992)
32. Farris RL, Stuchell RN, Mandel ID. Basal and reflex human tear analysis. I. Physical measurements: osmolarity, basal volumes, and reflex flow rate. Ophthalmology 1981;88:852-7. (Pubitemid 11039475)
33. Fullard RJ, Tucker DL. Changes in human tear protein levels with progressively increasing stimulus. Invest Ophthalmol Vis Sci 1991; 32:2290-301.
34. Shoham A, Hadziahmetovic M, Dunaief JL, Mydlarski MB, Schipper HM. Oxidative stress in diseases of the human cornea. Free Radic Biol Med 2008;45:1047-55.
35. Mishima S, Gasset A, Klyce SD Jr, Baum JL. Determination of tear volume and tear flow. Invest Ophthalmol 1966;5:264-76.
36. Craig JP, Tomlinson A. Effect of age on tear osmolality. Optom Vis Sci 1995;72:713-7.
37. Ozdemir M, Temizdemir H. Age- and gender-related tear function changes in normal population. Eye (Lond) 2010;24:79-83.
38. Rieger G. Anti-oxidative capacity of various artificial tear preparations. Graefes Arch Clin Exp Ophthalmol 2001;239:222-6. (Pubitemid 32422029)
39. Kuzuya M, Ando F, Iguchi A, Shimokata H. Effect of aging on serum uric acid levels: longitudinal changes in a large Japanese population group. J Gerontol A Biol Sci Med Sci 2002;57:M660-4.
40. Patel S, Plaskow J, Ferrier C. The influence of vitamins and trace element supplements on the stability of the pre-corneal tear film. Acta Ophthalmol (Copenh) 1993;71:825-9. (Pubitemid 24038783)
41. Drouault-Holowacz S, Bieuvelet S, Burckel A, Rigal D, Dubray C, Lichon JL, Bringer P, Pilon F, Chiambaretta F. Antioxidants intake and dry eye syndrome: a crossover, placebo-controlled, randomized trial. Eur J Ophthalmol 2009;19:337-42.
42. Kasetsuwan N, Wu FM, Hsieh F, Sanchez D, McDonnell PJ. Effect of topical ascorbic acid on free radical tissue damage and inflammatory cell influx in the cornea after excimer laser corneal surgery. Arch Ophthalmol 1999;117:649-52. (Pubitemid 29218432)
43. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine, 3rd ed. New York, NY: Oxford University Press; 1999.
44. Richer S. Antioxidants and the eye. Int Ophthalmol Clin 2000;40: 1-16.
45. Michalos P, Avila EN, Florakis GJ, Hersh PS. Do human tears absorb ultraviolet light? CLAO J 1994;20:192-3. (Pubitemid 24245918)
46. Kirshenbaum DM, ed. Atlas of Protein Spectra in the Ultraviolet and Visible Regions. New York, NY: IFI/Plenum; 1974.
47. Ringvold A, Anderssen E, Kjonniksen I. UV absorption by uric acid in diurnal bird aqueous humor. Invest Ophthalmol Vis Sci 2000;41: 2067-9. (Pubitemid 30450974)