Cytotoxicity and cytokine production by bovine alveolar macrophages challenged with wild type and leukotoxin-deficient Mannheimia haemolytica

Veterinary Journal

Volumn 188, Issue 2, 2011, Pages 221-227

  Singh, Kuldeep ^a   Confer, Anthony W ^a   Hope, Jayne C ^b   Rizzi, Theresa ^a   Wyckoff, John H ^a,d   Weng, Hsin Yi ^c   Ritchey, Jerry W ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Bovine alveolar macrophages; Cytokines; Leukotoxin; Mannheimia haemolytica

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEUKOTOXIN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; COW; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; LUNG ALVEOLUS MACROPHAGE; MANNHEIMIA HAEMOLYTICA; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE;

ANIMALS; CATTLE; CYTOKINES; CYTOTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXOTOXINS; IMMUNOSUPPRESSIVE AGENTS; MACROPHAGES, ALVEOLAR; MANNHEIMIA HAEMOLYTICA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VIRULENCE FACTORS;

BOVINAE; MANNHEIMIA HAEMOLYTICA;

EID: 79953783802     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2010.05.015     Document Type: Article

References (24)

1. Ambagala T.C., Ambagala A.P., Srikumaran S. The leukotoxin of Pasteurella haemolytica binds to β2 integrins on bovine leukocytes. FEMS Microbiology Letters 1999, 179:161-167.
2. Caswell J.L., Middleton D.M., Sorden S.D., Gordon J.R. Expression of the neutrophil chemoattractant interleukin-8 in the lesions of bovine pneumonic pasteurellosis. Veterinary Pathology 1998, 35:124-131.
3. Confer A.W., Panciera R.J., Clinkenbeard K.D., Mosier D.A. Molecular aspects of virulence of Pasteurella haemolytica. Canadian Journal of Veterinary Research 1990, 54:S48-S52.
4. Confer A.W., Clinkenbeard K.D., Gatewood D.M., Driskel B.A., Montelongo M. Serum antibody responses of cattle vaccinated with partially purified native Pasteurella haemolytica leukotoxin. Vaccine 1997, 15:1423-1429.
5. Confer A.W., Ayalew S., Panciera R.J., Montelongo M., Wray J.H. Recombinant Mannheimia haemolytica serotype 1 outer membrane protein PLPE enhances commercial M. haemolytica vaccine-induced resistance against serotype 6 challenge. Vaccine 2006, 24:2248-2255.
6. Highlander S.K. Molecular genetic analysis of virulence in Mannheimia (Pasteurella) haemolytica. Frontiers in Bioscience 2001, 6:D1128-D1150.
7. Highlander S.K., Fedorova N.D., Dusek D.M., Panciera R., Alvarez L.E., Rinehart C. Inactivation of Pasteurella (Mannheimia) haemolytica leukotoxin causes partial attenuation of virulence in a calf challenge model. Infection and Immunity 2000, 68:3916-3922.
8. Hurvich C.M., Tsai C.L. Model selection for extended quasi-likelihood models in small samples. Biometrics 1995, 51:1077-1084.
9. Jeyaseelan S., Kannan M.S., Hsuan S.L., Singh A.K., Walseth T.F., Maheswaran S.K. Pasteurella (Mannheimia) haemolytica leukotoxin-induced cytolysis of bovine leukocytes: role of arachidonic acid and its regulation. Microbial Pathogenesis 2001, 30:59-69.
10. Kenward M.G., Roger J.H. Small sample inference for fixed effects from restricted maximum likelihood. Biometrics 1997, 53:983-997.
11. Kwong L.S., Hope J.C., Thom M.L., Sopp P., Duggan S., Bembridge G.P., Howard C.J. Development of an ELISA for bovine IL-10. Veterinary Immunology and Immunopathology 2002, 85:213-223.
12. Lafleur R.L., Malazdrewich C., Jeyaseelan S., Bleifield E., Abrahamsen M.S., Maheswaran S.K. Lipopolysaccharide enhances cytolysis and inflammatory cytokine induction in bovine alveolar macrophages exposed to Pasteurella (Mannheimia) haemolytica leukotoxin. Microbial Pathogenesis 2001, 30:347-357.
13. Li J., Clinkenbeard K.D. Lipopolysaccharide complexes with Pasteurella haemolytica leukotoxin. Infection and Immunity 1999, 67:2920-2927.
14. Maheswaran S.K., Weiss D.J., Kannan M.S., Townsend E.L., Reddy K.R., Whiteley L.O., Srikumaran S. Effects of Pasteurella haemolytica A1 leukotoxin on bovine neutrophils: degranulation and generation of oxygen-derived free radicals. Veterinary Immunology and Immunopathology 1992, 33:51-68.
15. Malazdrewich C., Ames T.R., Abrahamsen M.S., Maheswaran S.K. Pulmonary expression of tumor necrosis factor α, interleukin-1β, and interleukin-8 in the acute phase of bovine pneumonic pasteurellosis. Veterinary Pathology 2001, 38:297-310.
16. Moore K.W., de Waal Malefyt R., Coffman R.L., O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annual Review of Immunology 2001, 19:683-765.
17. Murphy G.L., Whitworth L.C., Clinkenbeard K.D., Clinkenbeard P.A. Hemolytic activity of the Pasteurella haemolytica leukotoxin. Infection and Immunity 1995, 63:3209-3212.
18. Paulsen D.B., Confer A.W., Clinkenbeard K.D., Mosier D.A. Pasteurella haemolytica lipopolysaccharide-induced cytotoxicity in bovine pulmonary artery endothelial monolayers: inhibition by indomethacin. Veterinary Pathology 1995, 32:173-183.
19. Rice J.A., Carrasco-Medina L., Hodgins D.C., Shewen P.E. Mannheimia haemolytica and bovine respiratory disease. Animal Health Research Reviews 2007, 8:117-128.
20. Rottman J.B., Tompkins W.A., Tompkins M.B. A reverse transcription-quantitative competitive polymerase chain reaction (RT-qcPCR) technique to measure cytokine gene expression in domestic mammals. Veterinary Pathology 1996, 33:242-248.
21. Tatum F.M., Briggs R.E., Sreevatsan S.S., Zehr E.S., Ling Hsuan S., Whiteley L.O., Ames T.R., Maheswaran S.K. Construction of an isogenic leukotoxin deletion mutant of Pasteurella haemolytica serotype 1: characterization and virulence. Microbial Pathogenesis 1998, 24:37-46.
22. Thumbikat P., Briggs R.E., Kannan M.S., Maheswaran S.K. Biological effects of two genetically defined leukotoxin mutants of Mannheimia haemolytica. Microbial Pathogenesis 2003, 34:217-226.
23. Whiteley L.O., Maheswaran S.K., Weiss D.J., Ames T.R. Immunohistochemical localization of Pasteurella haemolytica A1-derived endotoxin, leukotoxin, and capsular polysaccharide in experimental bovine Pasteurella pneumonia. Veterinary Pathology 1990, 27:150-161.
24. Wyckoff J.H., Howland J.L., Scott C.M., Smith R.A., Confer A.W. Recombinant bovine interleukin 2 enhances immunity and protection induced by Brucella abortus vaccines in cattle. Veterinary Microbiology 2005, 111:77-87.