TP53 codon 72 polymorphism is associated with pancreatic cancer risk in males, smokers and drinkers

Molecular Medicine Reports

Volumn 4, Issue 3, 2011, Pages 489-495

  Sonoyama, Takayuki ^a   Sakai, Akiko ^a   Mita, Yuichiro ^a   Yasuda, Yukiko ^a   Kawamoto, Hirofumi ^a   Yagi, Takahito ^a   Yoshioka, Masao ^b   Mimura, Tetsushige ^b   Nakachi, Kei ^c   Ouchida, Mamoru ^a   Yamamoto, Kazuhide ^a   Shimizu, Kenji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b OKAYAMA SAISEIKAI GENERAL HOSPITAL   (Japan)

^c RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

Author keywords

Cancer; Pancreas; Polymorphism; Single nucleotide polymorphism; Tumor protein p53

Indexed keywords

ARGININE; PROLINE; PROTEIN P53;

ADULT; AGED; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; CANCER PATIENT; CANCER RISK; CODON; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

ADULT; AGED; ALCOHOL DRINKING; CASE-CONTROL STUDIES; CODON; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SMOKING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79953768745     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.449     Document Type: Article

References (52)

1. Foundation for Promotion of Cancer Research: Cancer Statistics in Japan, 2008.
2. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T and Thun MJ: Cancer Statistics, 2008. CA Cancer J Clin 58: 71-96, 2008.
3. Ferlay J, Autier P, Boniol M, Heanue M, Colombet M and Boyle P: Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 18: 581-592, 2007.
4. Pierantoni C, Pagliacci A, Scartozzi M, Berardi R, Bianconi M and Cascinu S: Pancreatic cancer: progress in cancer therapy. Crit Rev Oncol Hematol 67: 27-38, 2008.
5. Li D, Xie K, Wolff R and Abbruzzese JL: Pancreatic cancer. Lancet 363: 1049-1057, 2004. (Pubitemid 38410779)
6. Gold EB: Epidemiology of and risk factors for pancreatic cancer. Surg Clin North Am 75: 819-843, 1995.
7. Qiu D, Kurosawa M, Lin Y, et al: Overview of the epidemiology of pancreatic cancer focusing on the JACC Study. J Epidemiol 15: S157-S167, 2005. (Pubitemid 41410098)
8. Lowenfels AB, Maisonneuve P and Whitcomb DC: Risk factors for cancer in hereditary pancreatitis. International Hereditary Pancreatitis Study Group. Med Clin North Am 84: 565-573, 2000. (Pubitemid 30346152)
9. Lin Y, Tamakoshi A, Kawamura T, et al: An epidemiological overview of environmental and genetic risk factors of pancreatic cancer. Asian Pac J Cancer Prev 2: 271-280, 2001.
10. Lynch SM, Vrieling A, Lubin JH, et al: Cigarette smoking and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium. Am J Epidemiol 170: 403-413, 2009.
11. Partanen TJ, Vainio HU, Ojajarvi IA and Kauppinen TP: Pancreas cancer, tobacco smoking and consumption of alcoholic beverages: a case-control study. Cancer Lett 116: 27-32, 1997. (Pubitemid 27226146)
12. Inoue M, Noda M, Kurahashi N, et al: Impact of metabolic factors on subsequent cancer risk: results from a large-scale population-based cohort study in Japan. Eur J Cancer Prev 18: 240-247, 2009.
13. Michaud DS, Giovannucci E, Willett WC, Colditz GA, Stampfer MJ and Fuchs CS: Physical activity, obesity, height, and the risk of pancreatic cancer. JAMA 286: 921-929, 2001. (Pubitemid 33010338)
14. Everhart J and Wright D: Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis. JAMA 273: 1605-1609, 1995.
15. Huxley R, Ansary-Moghaddam A, Berrington de Gonzalez A, Barzi F and Woodward M: Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies. Br J Cancer 92: 2076-2083, 2005. (Pubitemid 40897433)
16. Ghadirian P, Baillargeon J, Simard A and Perret C: Food habits and pancreatic cancer: a case-control study of the Francophone community in Montreal, Canada. Cancer Epidemiol Biomarkers Prev 4: 895-899, 1995.
17. Larsson SC, Hakansson N, Giovannucci E and Wolk A: Folate intake and pancreatic cancer incidence: a prospective study of Swedish women and men. J Natl Cancer Inst 98: 407-413, 2006.
18. Bansal P and Sonnenberg A: Pancreatitis is a risk factor for pancreatic cancer. Gastroenterology 109: 247-251, 1995.
19. Lowenfels AB, Maisonneuve P, Cavallini G, et al: Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N Engl J Med 328: 1433-1437, 1993. (Pubitemid 23143844)
20. Ghadirian P, Lynch HT and Krewski D: Epidemiology of pancreatic cancer: an overview. Cancer Detect Prev 27: 87-93, 2003. (Pubitemid 36429586)
21. Landi S: Genetic predisposition and environmental risk factors to pancreatic cancer: a review of the literature. Mutat Res 681: 299-307, 2009.
22. Ockenga J, Vogel A, Teich N, Keim V, Manns MP and Strassburg CP: UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer. Gastroenterology 124: 1802-1808, 2003.
23. Li D, Jiao L, Li Y, et al: Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer. Carcinogenesis 27: 103-111, 2006. (Pubitemid 43025249)
24. Duell EJ, Holly EA, Bracci PM, Wiencke JK and Kelsey KT: A population-based study of the Arg399Gln polymorphism in X-ray repair cross- complementing group 1 (XRCC1) and risk of pancreatic adenocarcinoma. Cancer Res 62: 4630-4636, 2002.
25. Jiao L, Hassan MM, Bondy ML, Wolff RA, Evans DB, Abbruzzese JL and Li D: XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer. Am J Gastroenterol 103: 360-367, 2008. (Pubitemid 351248719)
26. Li D, Ahmed M, Li Y, et al: 5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev 14: 1470-1476, 2005. (Pubitemid 40807348)
27. Larsson SC, Giovannucci E and Wolk A: Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis. Gastroenterology 131: 1271-1283, 2006. (Pubitemid 44515102)
28. Ohnami S, Sato Y, Yoshimura K, et al: His595Tyr polymorphism in the methionine synthase reductase (MTRR) gene is associated with pancreatic cancer risk. Gastroenterology 135: 477-488, 2008.
29. Zhao D, Xu D, Zhang X, et al: Interaction of cyclooxygenase-2 variants and smoking in pancreatic cancer: a possible role of nucleophosmin. Gastroenterology 136: 1659-1668, 2009.
30. Popanda O, Edler L, Waas P, et al: Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. Lung Cancer 55: 25-34, 2007. (Pubitemid 46038874)
31. Fernandez-Rubio A, Lopez-Cima MF, Gonzalez-Arriaga P, Garcia-Castro L, Pascual T, Marron MG and Tardon A: The TP53 Arg72Pro polymorphism and lung cancer risk in a population of Northern Spain. Lung Cancer 61: 309-316, 2008.
32. Singh V, Rastogi N, Mathur N, Singh K and Singh MP: Association of polymorphism in MDM-2 and p53 genes with breast cancer risk in indian women. Ann Epidemiol 18: 48-57, 2008. (Pubitemid 350184342)
33. Cao Z, Song JH, Park YK, Maeng EJ, Nam SW, Lee JY and Park WS: The p53 codon 72 polymorphism and susceptibility to colorectal cancer in korean patients. Neoplasma 56: 114-118, 2009.
34. Jones JS, Chi X, Gu X, Lynch PM, Amos CI and Frazier ML: p53 polymorphism and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Clin Cancer Res 10: 5845-5849, 2004. (Pubitemid 39180964)
35. Yang M, Guo Y, Zhang X, et al: Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. Carcinogenesis 28: 1996-2001, 2007.
36. Zhu ZZ, Cong WM, Liu SF, Dong H, Zhu GS and Wu MC: Homozygosity for Pro of p53 Arg72Pro as a potential risk factor for hepatocellular carcinoma in Chinese population. World J Gastroenterol 11: 289-292, 2005. (Pubitemid 40125222)
37. Parhar P, Ezer R, Shao Y, Allen JC, Miller DC and Newcomb EW: Possible association of p53 codon 72 polymorphism with susceptibility to adult and pediatric high-grade astrocytomas. Mol Brain Res 137: 98-103, 2005. (Pubitemid 40798891)
38. Naccarati A, Pardini B, Polakova V, et al: Genotype and haplotype analysis of TP53 gene and the risk of pancreatic cancer: an association study in the Czech Republic. Carcinogenesis 31: 666-670, 2010.
39. Kanzaki H, Ouchida M, Hanafusa H, et al: Single nucleotide polymorphism in the RAD18 gene and risk of colorectal cancer in the Japanese population. Oncol Rep 18: 1171-1175, 2007.
40. Imyanitov EN: Gene polymorphisms, apoptotic capacity and cancer risk. Hum Genet 125: 239-246, 2009.
41. Pim D and Banks L: Polymorphic variants at codon 72 exert different effects on cell cycle progression. Int J Cancer 108: 196-199, 2004. (Pubitemid 37541770)
42. Dumont P, Leu JI, Della Pietra AC III, George DL and Murphy M: The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 33: 357-365, 2003. (Pubitemid 36278852)
43. Bergamaschi D, Samuels Y, Sullivan A, et al: iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53. Nat Genet 38: 1133-1141, 2006. (Pubitemid 44470358)
44. Lin Y, Tamakoshi A, Kawamura T, Inaba Y, Kikuchi S, Motohashi Y and Kurosawa M: JACC Study Group: a prospective cohort study of cigarette smoking and pancreatic cancer in Japan. Cancer Causes Control 13: 249-254, 2002. (Pubitemid 34438234)
45. Go VL, Gukovskaya A and Pandol SJ: Alcohol and pancreatic cancer. Alcohol 35: 205-211, 2005.
46. Inoue M and Tsugane S: JPHC Study Group: Impact of alcohol drinking on total cancer risk: data from a large-scale population-based cohort study in Japan. Br J Cancer 92: 182-187, 2005. (Pubitemid 40188453)
47. Malats N, Porta M, Corominas JM, Piñol JL, Rifà J and Real FX: Ki-ras mutations in exocrine pancreatic cancer: association with clinico-pathological characteristics and with tobacco and alcohol consumption. PANK-ras I Project Investigators. Int J Cancer 70: 661-667, 1997. (Pubitemid 27158444)
48. Suzuki H, Morris JS, Li Y, et al: Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. Carcinogenesis 29: 1184-1191, 2008.
49. El Hallani S, Ducray F, Idbaih A, et al: TP53 codon 72 polymorphism is associated with age at onset of glioblastoma. Neurology 72: 332-336, 2009.
50. Yoon YJ, Chang HY, Ahn SH, et al: MDM2 and p53 polymorphisms are associated with the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection. Carcinogenesis 29: 1192-1196, 2008. (Pubitemid 351964880)
51. Shen H, Zheng Y, Sturgis EM, Spitz MR and Wei Q: P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck: a case-control study. Cancer Lett 183: 123-130, 2002. (Pubitemid 34628415)
52. Ørsted DD, Bojesen SE, Tybjaerg-Hansen A and Nordestgaard BG: Tumor suppressor p53 Arg72Pro polymorphism and longevity, cancer survival, and risk of cancer in the general population. J Exp Med 204: 1295-1301, 2007.