A case of a girl presenting with fever, cytopenia, liver dysfunction, hepatosplenomegaly, and hemophagocytosis in the bone marrow

Journal of Clinical Virology

Volumn 51, Issue 1, 2011, Pages 1-3

  Gunson, R N ^a   Hague, R ^b   Gartner, B ^c   Aitken, C ^a  

^a GARTNAVEL GENERAL HOSPITAL   (United Kingdom)

^b ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; BONE MARROW; CASE REPORT; CYTOPENIA; EPSTEIN BARR VIRUS; ERYTHROPHAGOCYTOSIS; FEMALE; FEVER; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HEPATOSPLENOMEGALY; HUMAN; LEUKOPENIA; LIVER DYSFUNCTION; NOTE; PRIORITY JOURNAL; THROMBOCYTOPENIA;

ADOLESCENT; ANTIVIRAL AGENTS; BONE MARROW; DIAGNOSIS, DIFFERENTIAL; DRUG THERAPY, COMBINATION; EPSTEIN-BARR VIRUS INFECTIONS; EVIDENCE-BASED PRACTICE; FEMALE; FEVER; HEPATOMEGALY; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOLOGIC FACTORS; INFUSIONS, INTRAVENOUS; LIVER; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; SPLENOMEGALY;

EID: 79953759785     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2010.12.013     Document Type: Note

References (14)

1. Imashuku S. Clinical features and treatment strategies of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Crit Rev Oncol Hematol 2002, 44(December (3)):259-272. [review].
2. Henter J.I., Horne A., Aricó M., Egeler R.M., Filipovich A.H., Imashuku S., et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007, 48(February (2)):124-131.
3. N'guyen Y., Andreoletti L., Patey M., Lecoq-Lafon C., Cornillet P., Léon A., et al. Epstein-Barr virus primo infection in a 25-year-old man treated with azathioprine for Crohn's disease. J Clin Microbiol 2009, 47(April (4)):1252-1254. [Epub 2009 Feb 4].
4. Van Biervliet S., Velde S.V., De Bruyne R., De Looze D., De Vos M., Van Winckel M. Epstein-Barr virus related lymphoma in inflammatory bowel disease. Acta Gastroenterol Belg 2008, 71(January-March (1)):33-35.
5. Posthuma E.F., Westendorp R.G., van der Sluys Veer A., Kluin-Nelemans J.C., Kluin P.M., Lamers C.B. Fatal infectious mononucleosis: a severe complication in the treatment of Crohn's disease with azathioprine. Gut 1995, 36(February (2)):311-313.
6. Garrido Serrano A., Pérez Martín F., Guerrero Igea F.J., Galbarro Muñoz J., Palomo Gil S. Fatal infectious mononucleosis during azathioprine treatment in Crohn's disease. Gastroenterol Hepatol 2000, 23(January (1)):7-8.
7. Losco A., Gianelli U., Cassani B., Baldini L., Conte D., Basilisco G. Epstein-Barr virus-associated lymphoma in Crohn's disease. Inflamm Bowel Dis. 2004, 10(July (4)):425-429.
8. Bosman G., Langemeijer S.M., Hebeda K.M., Raemaekers J.M., Pickkers P., van der Velden W.J. The role of rituximab in a case of EBV-related lymphoproliferative disease presenting with haemophagocytosis. Neth J Med 2009, 67(September (8)):364-365.
9. Balamuth N.J., Nichols K.E., Paessler M., Teachey D.T. Use of rituximab in conjunction with immunosuppressive chemotherapy as a novel therapy for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. J Pediatr Hematol Oncol 2007, 29(August (8)):569-573.
10. Teramura T., Tabata Y., Yagi T., Morimoto A., Hibi S., Imashuku S. Quantitative analysis of cell-free Epstein-Barr virus genome copy number in patients with EBV-associated hemophagocytic lymphohistiocytosis. Leuk Lymphoma 2002, 43(January (1)):173-179.
11. Rouphael N.G., Talati N.J., Vaughan C., Cunningham K., Moreira R., Gould C. Infections associated with haemophagocytic syndrome. Lancet Infect Dis 2007, 7(December).
12. Imashuku S. Systemic type Epstein-Barr virus-related lymphoproliferative diseases in children and young adults: challenges for pediatric hemato-oncologists and infectious disease specialists. Pediatr Hematol Oncol 2007, 24(December (8)):563-568. [review].
13. Kaza U., Knight A.K., Jeroudi M., Bocchini J.A., Anga A., Bahna S.L. A boy with fever, lymphadenopathy, hepatosplenomegaly, and lymphocytosis. Allergy Asthma Proc 2008, 29(March-April (2)):216-220.
14. Gea-Banacloche J.C. Rituximab-Associated Infections Seminars in Hematology, vol. 47, no. April (2) 2010, 187-198.