Long-term proton pump inhibitor administration, H pylori and gastric cancer: Lessons from the gerbil

Gut

Volumn 60, Issue 5, 2011, Pages 567-568

  Fox, James G ^a   Kuipers, Ernst J ^b  

^a Massachusetts Institute of Technology   (United States)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

OMEPRAZOLE;

BACTERIAL COLONIZATION; CANCER GROWTH; CANCER INVASION; CANCER RISK; DISEASE ASSOCIATION; GASTRITIS; GERBIL; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HYPERGASTRINEMIA; NONHUMAN; NOTE; PRECANCER; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA; STOMACH ATROPHY; STOMACH CANCER; STOMACH CARCINOGENESIS; STOMACH DISEASE; TREATMENT DURATION;

ANIMALS; COCARCINOGENESIS; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; GERBILLINAE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; PROTON PUMP INHIBITORS; STOMACH NEOPLASMS;

EID: 79953750255     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2010.229286     Document Type: Note

References (20)

1. Danon SJ, O'Rourke JL, Moss ND, et al. The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach. Gastroenterology 1995;108:1386-95.
2. Kuipers EJ, Uyterlinde AM, Pena AS, et al. Increase of Helicobacter pylori-associated corpus gastritis during acid suppressive therapy: implications for long-term safety. Am J Gastroenterol 1995;90:1401-6.
3. Hagiwara T, Mukaisho K, Nakayama T, et al. Long-term proton pump inhibitor administration worsens atrophic corpus gastritis and promotes adenocarcinoma development in Mongolian gerbils infected with Helicobacter pylori. Gut 2011;60:624-30.
4. Fox JG, Wang TC. Inflammation, atrophy, and gastric cancer. J Clin Invest 2007;117:60-9. (Pubitemid 46048450)
5. Yokota K, Kurebayashi Y, Takayama Y, et al. Colonization of Helicobacter pylori in the gastric mucosa of Mongolian gerbils. Microbiol Immunol 1991;35:475-80.
6. Hirayama F, Takagi S, Kusuhara H, et al. Induction of gastric ulcer and intestinal metaplasia in mongolian gerbils infected with Helicobacter pylori. J Gastroenterol 1996;31:755-7. (Pubitemid 26345549)
7. Honda S, Fujioka T, Tokieda M, et al. Gastric ulcer, atrophic gastritis, and intestinal metaplasia caused by Helicobacter pylori infection in Mongolian gerbils. Scand J Gastroenterol 1998;33:454-60. (Pubitemid 28277242)
8. Honda S, Fujioka T, Tokieda M, et al. Development of Helicobacter pylori-induced gastric carcinoma in Mongolian gerbils. Cancer Res 1998;58:4255-9. (Pubitemid 28450020)
9. Watanabe T, Tada M, Nagai H, et al. Helicobacter pylori infection induces gastric cancer in mongolian gerbils. Gastroenterology 1998;115:642-8. (Pubitemid 28397299)
10. Hansson LE, Nyren O, Hsing AW, et al. The risk of stomach cancer in patients with gastric or duodenal ulcer disease. N Engl J Med 1996;335:242-9. (Pubitemid 26249572)
11. Wang TC, Goldenring JR, Dangler C, et al. Mice lacking secretory phospholipase A2 show altered apoptosis and differentiation with Helicobacter felis infection. Gastroenterology 1998;114:675-89. (Pubitemid 28160402)
12. Fox JG, Dangler CA, Taylor NS, et al. High-salt diet induces gastric epithelial hyperplasia and parietal cell loss, and enhances Helicobacter pylori colonization in C57BL/6 mice. Cancer Res 1999;59:4823-8. (Pubitemid 29472883)
13. Wang TC, Fox JG. Helicobacter pylori and gastric cancer: Koch's postulates fulfilled? Gastroenterology 1998;115:780-3.
14. Peek RM Jr, Wirth HP, Moss SF, et al. Helicobacter pylori alters gastric epithelial cell cycle events and gastrin secretion in Mongolian gerbils. Gastroenterology 2000;118:48-59. (Pubitemid 30020372)
15. Wang TC, Dangler CA, Chen D, et al. Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer. Gastroenterology 2000;118:36-47. (Pubitemid 30020371)
16. Lofgren JL, Whary MT, Ge Z, et al. Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology 2011;140:210-20.
17. Kuipers EJ, Lundell L, Klinkenberg-Knol EC, et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med 1996;334:1018-22. (Pubitemid 26123777)
18. Lundell L, Havu N, Miettinen P, et al. Changes of gastric mucosal architecture during long-term omeprazole therapy: results of a randomized clinical trial. Aliment Pharmacol Ther 2006;23:639-47.
19. Kuipers EJ. Proton pump inhibitors and gastric neoplasia. Gut 2006;55:1217-21. (Pubitemid 44277346)
20. Malfertheiner P, Megraud F, O'Morain C, et al. Current concepts in the management of Helicobacter pylori infection: the Maastricht III consensus report. Gut 2007;56:772-81. (Pubitemid 46854190)