Stage-dependent toxicity of 2,4-dichlorophenoxyacetic on the embryonic development of a South American toad, Rhinella arenarum

Environmental Toxicology

Volumn 26, Issue 4, 2011, Pages 373-381

  Aronzon, Carolina M ^a,b   Sandoval, María T ^a,c   Herkovits, Jorge ^a,b   Pérez Coll, Cristina S ^a,b,d  

^a Fundacion PROSAMA   (Argentina)

^b Consejo Nacional de Investigaciones Cientificas y Tecnicas ^*  (Argentina)

^c UNIVERSIDAD NACIONAL DEL NORDESTE   (Argentina)

^d UNIVERSIDAD NACIONAL DE SAN MARTÍN   (Argentina)

Author keywords

2,4 dichlorophenoxyacetic acid; Amphibian embryo; Commercial agrochemical; Embryonic development; Herbicide; Stage dependent toxicity; Teratogenesis

Indexed keywords

2 ,4-DICHLOROPHENOXYACETIC ACID; AMPHIBIAN EMBRYO; COMMERCIAL AGROCHEMICAL; EMBRYONIC DEVELOPMENT; STAGE-DEPENDENT TOXICITY; TERATOGENESIS;

AGRICULTURAL CHEMICALS; AIR POLLUTION CONTROL; CELL PROLIFERATION; TOXICITY; WEED CONTROL;

HERBICIDES;

2,4 DICHLOROPHENOXYACETIC ACID; HERBICIDE; TERATOGENIC AGENT;

AGROCHEMICAL; BODY SIZE; DOSE-RESPONSE RELATIONSHIP; ECOTOXICOLOGY; EMBRYO; EMBRYONIC DEVELOPMENT; HERBICIDE; NONTARGET ORGANISM; RISK FACTOR; TOAD; TOXICITY TEST; ULTRASTRUCTURE;

AGENESIS; ANIMAL EXPERIMENT; BODY SIZE; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; EDEMA; EMBRYO; EMBRYO DEVELOPMENT; GILL; LARVAL STAGE; LC 50; LETHALITY; MICROCEPHALY; NONHUMAN; PRIORITY JOURNAL; REVIEW; RHINELLA ARENARUM; TAIL; TERATOGENICITY; TOAD;

2,4-DICHLOROPHENOXYACETIC ACID; ABNORMALITIES, DRUG-INDUCED; ACUTE TOXICITY TESTS; ANIMALS; BUFONIDAE; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; GILLS; GLUTATHIONE PEROXIDASE; HERBICIDES; LETHAL DOSE 50; LIFE CYCLE STAGES; TERATOGENS; TOXICITY TESTS, CHRONIC;

AMPHIBIA; BUFO; BUFO AMERICANUS;

EID: 79953736617     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20564     Document Type: Review

References (47)

1. APHA, editor. 1980. Standard Methods for the Examination of Water and Wastewater. Washington, DC: American Public Health Association.
2. ASTM. 1993. Standard guide for conducting the Frog Embryo Teratogenesis Assay-Xenopus (FETAX).American Society for Testing and Materials. Standards on Aquatic Toxicology and Hazard Evaluation. Philadelphia, PA.
3. Ateeq B, Abul farah M, Niamat Ali M, Ahmad W. 2002. Induction of micronuclei and erythrocyte alterations in the catfish Clarias batrachus by 2, 4-dichlorophenoxyacetic acid and butachlor. Mutat Res 518: 135-144.
4. Brodeur JC, Svartz G, Perez-Coll CS, Marino DJG, Herkovits J. 2009. Comparative susceptibility to atrazine of three developmental stages of Rhinella arenarum and influence on metamorphosis: Non-monotonous acceleration of the time to climax and delayed tail resorption. Aquat Toxicol 91: 161-170.
5. Bueno-Guimarães H, Ferreira C, Garcia M, Saldiva P. 2001. Tadpole epithelium test: Potential use of Rana catesbeiana histopathologic epithelial changes to evaluate aquatic pollution. Bull Environ Contam Toxicol 67: 202-209.
6. Buslovich S, Borushko N. 1976. Chloroderivatives of phenoxyacetic acid as antagonists of thyroid hormones. Farmakol Toksikol 39: 481-483.
7. Castañaga LA, Asorey CM, Sandoval MT, Perez-Coll CS, Argibay TI, Herkovits J. 2009. Stage dependent teratogenic and lethal effects exerted by ultraviolet B radiation on Rhinella (Bufo) arenarum embryos. Environ Toxicol Chem 28: 427-433.
8. Charles JM, Hanley TRJ, Wilson RD, Van Ravenzwaay B, Bus JS. 2001. Developmental toxicity studies in rats and rabbits on 2, 4-dichlorophenoxyacetic acid and its forms. Toxicol Sci Mar 60: 121-131.
9. Del Conte E, Sirlin L. 1951. The first stages of Bufo arenarum development. Act Zoo Lilloana 12: 495-499.
10. EPA. 2004. EFED risk assessment for the registration eligibility document for 2, 4-dichlorophenoxyacetic acid (2, 4-D).
11. EPA US. 1988. Users guide for a computer program for PROBIT analisis of data from acute and short-term chronic toxicity test with aquatic organisms. Biological Methods, Environmental Monitoring and Support Lab.
12. Ferrari L, de la Torre F, Demichelis S, García M, Salibián A. 2005. Ecotoxicological assessment for receiving waters with the premetamorphic tadpoles acute assay. Chemosphere 59: 567-575.
13. Green RM, Abdelghani AA. 2004. Toxicity of a mixture of 2, 4-dichlorophenoxyacetic acid and mono-sodium methanearsonate to the red swamp crawfish, Procambarus clarkii. Int J Environ Res Public Health 1: 35-38.
14. Herkovits J, Cardellini P, Pavanati C, Pérez-Coll CS. 1997. Susceptibility of early life stages of Xenopus laevis to cadmium. Environ Toxicol Chem 16: 312-316.
15. Herkovits J, Helguero LA. 1998. Copper toxicity and copper-zinc interactions in amphibian embryos. Sci Total Environ 221: 1-10.
16. Herkovits J, Pérez-Coll C. 1995. Increased resistance against cadmium toxicity by means of pretreatment with low cadmium/zinc concentrations in Bufo arenarum embryos. Biol Trace Elem Res 49: 171-175.
17. Herkovits J, Pérez-Coll C. 2000. Evaluation of nickel-zinc interactions by means of bioassays with amphibian embryos. Ecotox Environ Safe 45: 266-273.
18. Herkovits J, Pérez-Coll C, Herkovits F. 1996. Ecotoxicity in the Reconquista River, province of Buenos Aires. Argentina: A preliminary study. Environ. Health Perspect 104: 186-189.
19. Herkovits J, Pérez-Coll CS. 2003. Symposium on multiple stressor effects in relation to declining amphibian populations. AMPHITOX: A customized set of toxicity tests employing amphibian embryos. In: Linder GL, Krest S, Sparling D, Little EE, editors. Multiple Stressor Effects in Relation to Declining Amphibian Populations. ASTM International STP 1443. USA. pp 46-60.
20. Herkovits J, Pérez-Coll CS, Herkovits F. 2002. Ecotoxicological studies of environmental samples from Buenos Aires area using a standardized amphibian embryo toxicity test (AMPHITOX). Environ Pollut 116: 177-183.
21. Hess FD. 1993. Herbicides effects on plants structure, physiology and biochemistry. In: Altman J, editor. Pesticide Interactions in Crop Production: Beneficial and Deleterious Effects. Boca Raton: CRC Press.
22. Hoekstra JA. 1993. Statistics in Ecotoxicology. Vrije Universiteit Academisch Proefschrift.
23. Houlahan JE, Findlay CS. 2000. Quantitative evidence for global amphibian population declines. Nature 404: 752-755.
24. IPCS. 1989. 2, 4-dichlorophenoxyacetic acid (2, 4-D)- Environmental aspects. Genova: World Health Organization. Report on Environmental Health Criteria 84.
25. Izaguirre MF, Lajmanovich RC, Peltzer PM, Soler AP, Casco VH. 2008. Cypermethrin-induced apoptosis in the Telencephalon of Physalaemus biligonigerus tadpoles (Anura: Leptodactylidae). Bull Environ Contam Toxicol 65: 501-507.
26. LaChapelle AM, Ruygrok ML, Toomer M, Oost JJ, Monnie ML, Swenson JA, Compton AA, Stebbins-Boaz B. 2007. The hormonal herbicide, 2, 4-dichlorophenoxyacetic acid, inhibits Xenopus oocyte maturation by targeting translational and post-translational mechanisms. Reproduc Toxicol 23: 20-31.
27. Losthe J, Roth P. 1946. Sur l'action des solutions aqueuses de 2, 4-Dichphénxyacétate de sodium sur l'évolution des oeufs de Rana temporaria. L Soc Biol 140: 272-273.
28. Mann RM, Bidwell JR. 2001. The acute toxicity of agricultural surfactants to the tadpoles of four Australian and two exotic frog. Environ Pollut 114: 195-205.
29. McKinlay R, Plant JA, Bell JNB, Voulvoulis N. 2008. Endocrine disrupting pesticides: Implications for risk assessment. Environ Int 34: 168-183.
30. Morgan MK, Scheuerman PR, Bishop CS, Pyles RA. 1996. Teratogenic potential of antrazine and 2, 4-D using FETAX. J Toxicol Environ Health 48: 151-168.
31. Oruc EO, Sevgiler Y, Uner Nl. 2004. Tissue-specific oxidative stress responses in fish exposed to 2, 4-D and azinphosmethy. Comp Biochem Physiol C Toxicol Pharmacol 137: 43-51.
32. Ouellet M, Bonin J, Rodrigue J, DesGranges J, Lair S. 1997. Hindlimb deformities (ectromelia, ectrodactyly) in free-living anurans form agricultural habitats. J Wildl Dis 33: 95-104.
33. Palma G, Sanchez A, Olave Y, Encina F, Palma R, Barra R. 2004. Pesticide levels in surface waters in an agricultural-forestry basin in Southern Chile. Chemosphere 57: 763-770.
34. Palmeira CM, Moreno AJ, Madeira VMC. 1994. Metabolic alterations in hepatocytes promoted by the herbicides paraquat, dinoseb, and 2, 4-D. Arch Toxicol 68: 24-31.
35. Pérez-Coll C, Herkovits J. 2006. Synergistic effects of copper and butylic ester of 2, 4-Dichlorophenoxyacetic acid (Esternon Ultra) on amphibian embryos. Int J Environ Res Public Health 3: 343-347.
36. Pérez-Coll CS, Herkovits J. 1990. Stage dependent susceptibility to lead in Bufo arenarum embryos. Environ Pollut 63: 239245.
37. Rivarola V, Mori G, Balegno H. 1992. 2, 4-Dichlorophenoxyacetic acid action on in vitro protein synthesis and its relation to polyamines. Drug Chem Toxicol 15: 245-257.
38. Rodríguez EM, Amín OA. 1991. Acute toxicity of parathion and 2, 4-D to larval and juvenile stage of Chasmagnatuthus granulata (Decapoda, Brachyura). Bull Environ Contam Toxicol 47: 634-640.
39. Rosso SB, Caceres AO, de Duffard AM, Duffard RO, Quiroga S. 2000. 2, 4-Dichlorophenoxyacetic acid disrupts the cytoskeleton and disorganizes the Golgi apparatus of cultured neurons. Toxicol Sci Mar 56: 133-140.
40. Schmidt C. 1997. Amphibian deformities continue to puzzle researchers. Environ Sci Technol A 31: 324-326.
41. Simms C. 1969. Indications of the decline of breeding amphibians at an isolated pond in marginal land, 1954 1967. Br J Herpetol 4: 93-96.
42. Stebbins-Boaz B, Fortner K, Frazier J, Piluso S, Pullen S, Rasar M, Reid W, Sinclair K, Winger E. 2004. Oocyte maturation in Xenopus laevis is blocked by the hormonal herbicide, 2, 4-dichlorophenoxy acetic acid. Mol Reprod Dev 67: 233-242.
43. van der Schalie WH, Gardner HSJr, Bantle JA, De Rosa CT, Finch RA, Reif JS, Reuter RH, Backer LC, Burger J, Folmar LC, Stokes WS. 1999. Animals as sentinels of human health hazards of environmental chemicals. Environ Health Perspect 107: 309-315.
44. Venkov P, Topashka-Ancheva M, Georgieva M, Alexieva V, Karanov E. 2000. Genotoxic effect of substituted phenoxyacetic acids. Arch Toxicol 74: 560-566.
45. Wake DB, Vredenburg VT. 2008. Are we in the midst of the sixth mass extinction? A view from the world of amphibians. Proc Natl Acad Sci 105( Suppl 1): 11466-11473.
46. Wauchope RD, Buttler TM, Hornsby AG, Augustijn-Beckers PWM, Burt JP. 1992. Pesticide properties database for environmental decision making. Rev Environ Contam Toxicol 123(SCS/ARS/CES): 7-22.
47. Zimdahi RL. 1993. Fundamentals of Weed Science. San Diego CA: Academic Press.