Narrowed lumen of the right coronary artery in chronic chagasic patients is associated with ischemic lesions of segmental thinnings of ventricles;El lumen estrecho de la arteria coronaria derecha en pacientes chagásicos crónicos está asociado con lesions de adelgazamientos segmentales de los ventrículos

Investigacion Clinica

Volumn 51, Issue 4, 2010, Pages 531-539

  Sambiase, Nadia Vieira ^a   Higuchi, Maria Lourdes ^a   Benvenuti, Luiz Alberto ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Arrhythmia; Cha as' disease; Fibrosis; Ischemic lesions; Steal phenomena

Indexed keywords

ADULT; ARTERY STEAL SYNDROME; ARTICLE; CHAGAS DISEASE; CHRONIC CHAGASIC CARDIOPATHY; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HEART DILATATION; HEART MUSCLE ISCHEMIA; HEART VENTRICLE WALL; HEART WEIGHT; HISTOLOGY; HUMAN; MALE; RIGHT CORONARY ARTERY; ANTHROPOMETRY; COMPARATIVE STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY OBSTRUCTION; CORONARY BLOOD VESSEL; HEART ARRHYTHMIA; HEART FAILURE; HEART VENTRICLE; MIDDLE AGED; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; SUDDEN DEATH; VASODILATATION;

ADULT; ANTHROPOMETRY; ARRHYTHMIAS, CARDIAC; CHAGAS CARDIOMYOPATHY; CORONARY CIRCULATION; CORONARY STENOSIS; CORONARY VESSELS; DEATH, SUDDEN; FEMALE; HEART FAILURE; HEART VENTRICLES; HUMANS; MALE; MIDDLE AGED; ORGAN SIZE; VASODILATION;

EID: 79953735078     PISSN: 05355133     EISSN: 05355133     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Rossi MA, Bestetti RB. Hipótese Unificada sobre a patoǵênese da cardiopatia chǵásica crônica. Implicações terapêuticas. Arq Bras Cardiol 1995; 64:255-260.
2. Rosenbaum MB, Alvarez AJ. The electrocardiogram in chronic chagasic myocarditis. Am Heart J 1955; 50:492-527.
3. Andrade ZA, Andrade SG, Oliveira GB. Histopathology of the conducting tissue of the heart in Chagas' myocarditis. Am Heart J 1978; 93:316-324.
4. Kramer JB, Saffitz JE, Witkowski FX. Intramural reentry as a mechanism of ventricular tachycardia during evolving canine myocardial infarction. Circ Res 1985; 56:736-754.
5. Acquatella H, Schiller NB, Puiǵbó JJ, Giordano H, Suárez JA, Casal H, Arreaza N, Valecillos R, Hirschaut E. M-mode and two-dimensional echocardioǵraphy in chronic Chaǵas' heart disease. Circulation 1980; 62:787-799.
6. Cunha Neto, E, Duranti M, Gruber A Z. Autoimmunity in Chaǵas' disease cardiopathy: bioloǵical relevance of cardiac myosin-specific epitope cross-reactive to an immunodominant Trypanosoma cruzi antigen. Proc Nat Ac Sc 1995; 92:3541-3545.
7. Higuchi Ml, Brito T, Reis MM, Barbosa A, Bellotti G, Barreto ACP, Pileggi F. Correlation between Trypanosoma cruzi parasitism and myocardial inflammatory infiltrate in human chronic chagasic myocarditis: Light microscopy and immunohistochemical findings. Cardiovasc Pathol 1993; 2: 101-106.
8. Palomino SAP, Aiello VD, Higuchi ML. Systematic mapping of hearts from chronic chagasic patients: the association between the occurrence of histopathological lesions and Trypanosoma cruzi antigens. Ann Trop Med Parasitol 2000; 94:571-579.
9. Reis MM, Higuchi ML, Benvenuti LA. An in situ quantitative immunohistochemical study of cytokines and IL-2R in chronic human chagasic myocarditis: correlation with the presence of myocardial Trypanosoma cruzi antigens. Clin Immunopathol 1997; 83:165-172.
10. Higuchi ML, Fukasawa S, Brito T. Different microcirculatory and interstitial matrix patterns in idiopathic dilated cardiomyopathy and Chaǵas' disease: a three dimensional confocal microscopy study. Heart 1999; 82:270-285.
11. Rossi MA. Microvascular changes as a cause of chronic cardiomyopathy in Chaǵas' disease. Am Heart J 1990; 120:233-236.
12. Rossi MA, Bestetti RB. The challenge of chagasic cardiomyopathy: the pathological roles of autonomic abnormalities, autoimmune mechanisms and Microvascular changes, and therapeutic implications. Cardiol 1995; 86:1-7.
13. Ramos SG, Rossi MA. Microcirculation and Chaǵas' disease hypothesis and recent results. Rev Inst Med Trop S Paulo 1999; 41:123-129.
14. Factor SM, Cho S, Wittner M. Abnormalities of the coronary circulation in acute murine Chaǵas' disease. Ann Trop Med Hyg 1985; 34:246-253.
15. Higuchi ML. Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities. Mem Inst Oswaldo Cruz 1999; 94:223-227.
16. Rochitte CE, Oliveira PF, Andrade JM. Myocardial delayed enhancement by mag-netic resonance imaging in patients with Chagas' disease. J Am Coll Cardiol 2005; 46:1553-1558.
17. Scanavacca M, Sosa E, D'Avila AL. Higuchi ML. Radiofrequency ablation of sustained ventricular tachycardia related to the mitral isthmus in Chaǵas' disease. PACE 2002, 25:368-371.
18. Stevenson WG. Mechanisms and management of arrhythmias in heart failure. Cur Opin Cardiol 1995; 10:274-281.
19. de Bakker JM, Coronel R, Tasseron S, Wilde AM, Opthof T, Jansen MJ, van Capelle FJL, Becker A E, Jambroes G. Ventricular tachycardia in the infarcted, Langendorff-perfused human hearts role of the arrangement of surviving cardiac fibers. J Am Col of Cardiol 1990; 15:1594-1607.
20. Bakker JMT, van Capelle FJL, Janse MJ. Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation. Circul 1988; 77:589-606.
21. Yutani C, Imakita M, Ishibashi UH. Histopathological analysis of surgically resected myocardium in patients with sustained ventricular tachycardia. Acta Pathol 1988; 38:605-613.
22. Tavora MZ, Mehta N, Silva RM. Characteristics and identification of sites of chagasic ventricular tachycardia by endocardial mapping. Arq Bras Cardiol 1999; 72: 451-474.
23. Higuchi ML, Benvenuti LA, Reis MM, Metzger M. Pathophysiology of the heart in Chagas' disease: current status and new developments. Cardiovasc Res 2003; 60: 96:107.
24. Rochitte CE, Nacif MS, de Oliveira Junior AC, Siqueira-Batista R, Marchiori E. Cardiac magnetic resonance in Chaǵas' disease. Artif Organs 2007; 31:259-267.
25. Rossi MA. Chronic Chagas cardiopathy as a model for an insight on the pathogenesis of arrhythmogenic right ventricular cardiomyopathy. Arq Bras Cardiol 1995; 65:3-5.
26. Torres FW, Acquatella H, Condado JA, Dinsmore R, Palacios IF. Coronary vascular reactivity is abnormal in patients with Chaǵas' disease. Am Heart J 1995; 129: 995-1001.
27. Libby P, Alroy J, Pereira ME. A neuraminidase from Trypanosoma cruzi removes sialic acid from the surface of mammalian myocardial and endothelial cells. J Clin Invest 1986; 77:127-135.