메뉴 건너뛰기




Volumn 7, Issue 4, 2011, Pages 477-480

Missing heritability, next-generation genome-wide association studies and primary cancer prevention: An Atlantean illusion?

Author keywords

cancer; genome sequencing; genome wide association studies; missing heritability; prevention

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

EID: 79953727577     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.11.29     Document Type: Review
Times cited : (8)

References (21)
  • 2
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio TA, Collins FS, Cox NJ: Finding the missing heritability of complex diseases. Nature 461(7265), 747-753 (2009).
    • (2009) Nature , vol.461 , Issue.7265 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 3
    • 78049407733 scopus 로고    scopus 로고
    • Genomics: The search for association
    • Baker M: Genomics: the search for association. Nature 467(7319), 1135-1138 (2010).
    • (2010) Nature , vol.467 , Issue.7319 , pp. 1135-1138
    • Baker, M.1
  • 5
    • 79951481957 scopus 로고    scopus 로고
    • Initial impact of the sequencing of the human genome
    • Lander ES: Initial impact of the sequencing of the human genome. Nature 470(7333), 187-197 (2011).
    • (2011) Nature , vol.470 , Issue.7333 , pp. 187-197
    • Lander, E.S.1
  • 6
    • 15544381256 scopus 로고    scopus 로고
    • Prevention and management of hereditary breast cancer
    • DOI 10.1200/JCO.2005.10.035
    • Narod SA, Offt K: Prevention and management of hereditary breast cancer. J. Clin. Oncol. 23(8), 1656-1663 (2005). (Pubitemid 46211420)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.8 , pp. 1656-1663
    • Narod, S.A.1    Offit, K.2
  • 7
    • 79952275252 scopus 로고    scopus 로고
    • Genome-sequencing anniversary Genomics and clinical relevance
    • Hudson T: Genome-sequencing anniversary Genomics and clinical relevance. Science 331(6017), 547 (2011).
    • (2011) Science , vol.331 , Issue.6017 , pp. 547
    • Hudson, T.1
  • 8
    • 77956511576 scopus 로고    scopus 로고
    • Prostate cancer screening: Current status and future perspectives
    • Strope SA, Andriole GL: Prostate cancer screening: current status and future perspectives. Nat. Rev. Urol. 7(9), 487-493 (2010).
    • (2010) Nat. Rev. Urol. , vol.7 , Issue.9 , pp. 487-493
    • Strope, S.A.1    Andriole, G.L.2
  • 9
    • 77957123338 scopus 로고    scopus 로고
    • Screening mammography-A long run for a short slide?
    • Welch HG: Screening mammography-a long run for a short slide? N Engl. J. Med. 363(13), 1276-1278 (2010).
    • (2010) N Engl. J. Med. , vol.363 , Issue.13 , pp. 1276-1278
    • Welch, H.G.1
  • 10
    • 67650924286 scopus 로고    scopus 로고
    • Review of the Lynch syndrome: History, molecular genetics, screening, differential diagnosis and medicolegal ramifcations
    • Lynch HT, Lynch PM, Lanspa SJ, Snyder CL, Lynch JF, Boland CR: Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis and medicolegal ramifcations. Clin. Genet. 76(1), 1-18 (2009).
    • (2009) Clin. Genet. , vol.76 , Issue.1 , pp. 1-18
    • Lynch, H.T.1    Lynch, P.M.2    Lanspa, S.J.3    Snyder, C.L.4    Lynch, J.F.5    Boland, C.R.6
  • 13
    • 77954407332 scopus 로고    scopus 로고
    • Genomewide association studies and assessment of the risk of disease
    • Manolio TA: Genomewide association studies and assessment of the risk of disease. N. Engl. J. Med. 363(2), 166-176 (2010).
    • (2010) N. Engl. J. Med. , vol.363 , Issue.2 , pp. 166-176
    • Manolio, T.A.1
  • 14
    • 77954133026 scopus 로고    scopus 로고
    • Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    • Park JH, Wacholder S, Gail MH et al.: Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat. Genet. 42(7), 570-575 (2010).
    • (2010) Nat. Genet. , vol.42 , Issue.7 , pp. 570-575
    • Park, J.H.1    Wacholder, S.2    Gail, M.H.3
  • 15
    • 77953688386 scopus 로고    scopus 로고
    • Million women study collaborators: Gene-environment interactions in 7610 women with breast cancer: Prospective evidence from the million women study
    • Travis RC, Reeves GK, Green J et al.; Million Women St udy Collaborators: Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study. Lancet 375(9732), 2143-2151 (2010);
    • (2010) Lancet , vol.375 , Issue.9732 , pp. 2143-2151
    • Travis, R.C.1    Reeves, G.K.2    Green, J.3
  • 16
    • 79953682172 scopus 로고    scopus 로고
    • Erratum
    • Erratum in: Lancet 375(9732), 2142 (2010).
    • (2010) Lancet , vol.375 , Issue.9732 , pp. 2142
  • 17
    • 77953547318 scopus 로고    scopus 로고
    • Genes, the environment, and breast cancer
    • Narod SA: Genes, the environment, and breast cancer. Lancet 375(9732), 2123-2124 (2010).
    • (2010) Lancet , vol.375 , Issue.9732 , pp. 2123-2124
    • Narod, S.A.1
  • 18
    • 77949578084 scopus 로고    scopus 로고
    • Performance of common genetic variants in breast-cancer risk models
    • Wacholder S, Hartge P, Prentice R et al.: Performance of common genetic variants in breast-cancer risk models. N Engl. J. Med. 362(11), 986-993 (2010).
    • (2010) N Engl. J. Med. , vol.362 , Issue.11 , pp. 986-993
    • Wacholder, S.1    Hartge, P.2    Prentice, R.3
  • 19
    • 79951472909 scopus 로고    scopus 로고
    • Charting a course for genomic medicine from base pairs to bedside
    • National Human Genome Research Institute
    • Green ED, Guyer MS; National Human Genome Research Institute: Charting a course for genomic medicine from base pairs to bedside. Nature 470(7333), 204-213 (2011).
    • (2011) Nature , vol.470 , Issue.7333 , pp. 204-213
    • Green, E.D.1    Guyer, M.S.2
  • 20
    • 77956331627 scopus 로고    scopus 로고
    • Integrating common and rare genetic variation in diverse human populations
    • International HapMap 3 Consortium
    • International HapMap 3 Consortium; Altshuler DM, Gibbs RA, Peltonen L et al.: Integrating common and rare genetic variation in diverse human populations. Nature 467(7311) 52-58 (2010).
    • (2010) Nature , vol.467 , Issue.7311 , pp. 52-58
    • Altshuler, D.M.1    Gibbs, R.A.2    Peltonen, L.3
  • 21
    • 77951115122 scopus 로고    scopus 로고
    • International network of cancer genome projects
    • Hudson TJ, Anderson W, Artez A et al.: International network of cancer genome projects. Nature 464, 993-998 (2010).
    • (2010) Nature , vol.464 , pp. 993-998
    • Hudson, T.J.1    Anderson, W.2    Artez, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.