Erythropoietin increases circulating endothelial progenitor cells and reduces the formation and progression of cerebral aneurysm in rats

Neuroscience

Volumn 181, Issue , 2011, Pages 292-299

  Xu, Y ^a   Tian, Y ^a   Wei, H J ^a   Chen, J ^b   Dong, J F ^a,c   Zacharek, A ^b   Zhang, J N ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b HENRY FORD HOSPITAL   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Animal model; Cerebral aneurysm; Endothelial progenitor cell; Erythropoietin

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ERYTHROPOIETIN; GELATINASE A; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL WALL THICKNESS; ARTERY DIAMETER; ARTERY MEDIA; ARTICLE; BONE MARROW; BRAIN ARTERY ANEURYSM; BRAIN BLOOD FLOW; CELL HOMING; CONTROLLED STUDY; DISEASE COURSE; DISEASE MARKER; ENDOTHELIAL PROGENITOR CELL; HEMODYNAMICS; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL MOBILIZATION; SURGICAL STRESS;

ANIMALS; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ERYTHROPOIETIN; INTRACRANIAL ANEURYSM; MALE; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS;

EID: 79953726284     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.02.051     Document Type: Article

References (39)

1. Aoki T., Kataoka H., Ishibashi R., Nozaki K., Hashimoto N. Simvastatin suppresses the progression of experimentally induced cerebral aneurysms in rats. Stroke 2008, 39:1276-1285.
2. Aoki T., Kataoka H., Morimoto M., Nozaki K., Hashimoto N. Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats. Stroke 2007, 38:162-169.
3. Asahara T., Takahashi T., Masuda H., Kalka C., Chen D.H., Iwaguro H., Inai Y., Silver M., Isner J.M. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 1999, 18:3964-3972.
4. Bahlmann F.H., de Groot K., Spandau J.M., Landry A.L., Hertel B., Duckett T., Boehm S.M., Menne J., Haller H., Fliser D. Erythropoietin regulates endothelial progenitor cells. Blood 2004, 103:921-926.
5. Brines M.L., Ghezzi P., Keenan S., Agnello D., de Lanerolle N.C., Cerami C., Itri L.M., Cerami A. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci U S A 2000, 97:10526-10531.
6. Burger D., Lei M., Geoghegan-Morphet N., Lu X., Xenocostas A., Feng Q. Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase. Cardiovasc Res 2006, 72:51-59.
7. de Boer H.C., Verseyden C., Ulfman L.H., Zwaginga J.J., Bot I., Biessen E.A., Rabelink T.J., van Zonneveld A.J. Fibrin and activated platelets cooperatively guide stem cells to a vascular injury and promote differentiation towards an endothelial cell phenotype. Arterioscler Thromb Vasc Biol 2006, 26:1653-1659.
8. Dong C., Goldschmidt-Clermont P.J. Endothelial progenitor cells: a promising therapeutic alternative for cardiovascular disease. J Interv Cardiol 2007, 20:93-99.
9. Dzau V.J., Gnecchi M., Pachori A.S., Morello F., Melo L.G. Therapeutic potential of endothelial progenitor cells in cardiovascular diseases. Hypertension 2005, 46:7-18.
10. Fukuda S., Hashimoto N., Naritomi H., Nagata I., Nozaki K., Kondo S., Kurino M., Kikuchi H. Prevention of rat cerebral aneurysm formation by inhibition of nitric oxide synthase. Circulation 2000, 101:2532-2538.
11. Gao L., Hoi Y.M., Swartz D.D., Kolega J., Siddiqui A., Meng H. Nascent aneurysm formation at the basilar terminus induced by hemodynamics. Stroke 2008, 39:2085-2090.
12. Genc K., Genc S., Baskin H., Semin I. Erythropoietin decreases cytotoxicity and nitric oxide formation induced by inflammatory stimuli in rat oligodendrocytes. Physiol Res 2006, 55:33-38.
13. Griese D.P., Ehsan A., Melo L.G., Kong D., Zhang L., Mann M.J., Pratt R.E., Mulligan R.C., Dzau V.J. Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. Circulation 2003, 108:2710-2715.
14. Hamed S., Barshack I., Luboshits G., Wexler D., Deutsch V., Keren G., George J. Erythropoietin improves myocardial performance in doxorubicin-induced cardiomyopathy. Eur Heart J 2006, 27:1876-1883.
15. Hashimoto T., Meng H., Young W.L. Intracranial aneurysms: links among inflammation, hemodynamics and vascular remodeling. Neurol Res 2006, 28:372-380.
16. Hazama F., Kataoka H., Yamada E., Kayembe K., Hashimoto N., Kojima M., Kim C. Early changes of experimentally induced cerebral aneurysms in rats. Light-microscopic study. Am J Pathol 1986, 124:399-404.
17. Heeschen C., Aicher A., Lehmann R., Fichtischerer S., Vasa M., Urbich C., Mildner-Rihm C., Martin H., Zeiher A.M., Dimmeler S. Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood 2003, 102:1340-1346.
18. Hristov M., Weber C. Endothelial progenitor cells: characterization, pathophysiology, and possible clinical relevance. J Cell Mol Med 2004, 8:498-508.
19. Imanishi T., Moriwaki C., Hano T., Nishio I. Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension. J Hypertens 2005, 23:1831-1837.
20. Iwai M., Cao G.D., Yin W., Stetler R.A., Liu J.L., Chen J. Erythropoietin promotes neuronal replacement through revascularization and neurogenesis after neonatal hypoxia/ischemia in rats. Stroke 2007, 38:2795-2803.
21. Kojima M., Handa H., Hashimoto N., Kim C., Hazama F. Early changes of experimentally induced cerebral aneurysms in rats: scanning electron microscopic study. Stroke 1986, 17:835-841.
22. Kondo S., Hashimoto N., Kikuchi H., Hazama F., Nagata I., Kataoka H., Rosenblum W.I. Apoptosis of medial smooth muscle cells in the development of saccular cerebral aneurysms in rats [editorial comment]. Stroke 1998, 29:181-189.
23. Kondo T., Hayashi M., Takeshita K., Numaguchi Y., Kobayashi K., Iino S., Inden Y., Murohara T. Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers. Arterioscler Thromb Vasc Biol 2004, 24:1442-1447.
24. Kong D., Melo L.G., Gnecchi M., Zhang L., Mostoslavsky G., Liew C.C., Pratt R.E., Dzau V.J. Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries. Circulation 2004, 110:2039-2046.
25. Leone A.M., Valgimigli M., Giannico M.B., Zaccone V., Perfetti M., D'Amario D., Rebuzzi A.G., Crea F. From bone marrow to the arterial wall: the ongoing tale of endothelial progenitor cells. Eur Heart J 2009, 30:890-899.
26. Maiese K., Li F., Chong Z.Z. New avenues of exploration for erythropoietin. JAMA 2005, 293:90-95.
27. Murasawa S., Asahara T. Review: cardiogenic potential of endothelial progenitor cells. Ther Adv Cadiovasc Dis 2008, 2:341-348.
28. Peichev M., Naiyer A.J., Pereira D., Zhu Z., Lane W.J., Williams M., Oz M.C., Hicklin D.J., Witte L., Moore M.A., Rafii S. Expression of VEGFR-2 and ac133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 2000, 95:952-958.
29. Ribatti D., Presta M., Vacca A., Ria R., Giuliani R., Dell'Era P., Nico B., Roncali L., Dammacco F. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Blood 1999, 93:2627-2636.
30. Ribatti D., Vacca A., Roccaro A.M., Crivellato E., Presta M. Erythropoietin as an angiogenic factor. Eur J Clin Invest 2003, 33:891-896.
31. Rouhl R.P.W., van Oostenbrugge R.J., Damoiseaux J., Tervaert J.W.C., Lodder J. Endothelial progenitor cell research in stroke-a potential shift in pathophysiological and therapeutical concepts. Stroke 2008, 39:2158-2165.
32. Scheubel R.J., Zorn H., Silber R.-E., Kuss O., Morawietz H., Holtz J., Simm A. Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting. J Am Coll Cardiol 2003, 42:2073-2080.
33. Shantsila E., Watson T., Lip G.Y.H. Endothelial progenitor cells in cardiovascular disorders. J Am Coll Cardiol 2007, 49:741-752.
34. Tamura T., Jamous M.A., Kitazato K.T., Yagi K., Tada Y., Uno M., Nagahiro S. Endothelial damage due to impaired nitric oxide bioavailability triggers cerebral aneurysm formation in female rats. J Hypertens 2009, 27:1284-1292.
35. Traub O., Berk B.C. Laminar shear stress-mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 1998, 18:677-685.
36. Tulamo R., Frosen J., Hernesniemi J., Niemela M. Inflammatory changes in the aneurysm wall: a review. J Neurointerv Surg 2009, 2:120-130.
37. van der Meer P., Lipsic E., Henning R.H., Boddeus K., van der Velden J., Voors A.A., van Veldhuisen D.J., van Gilst W.H., Schoemaker R.G. Erythropoietin induces neovascularization and improves cardiac function in rats with heart failure after myocardial infarction. J Am Coll Cardiol 2005, 46:125-133.
38. Westenbrink B.D., Lipsic E., van der Meer P., van der Harst P., Oeseburg H., Du Marchie Sarvaas G.J., Koster J., Voors A.A., van Veldhuisen D.J., van Gilst W.H., Schoemaker R.G. Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization. Eur Heart J 2007, 28:2018-2027.
39. Zampetaki A., Kirton J.P., Xu Q. Vascular repair by endothelial progenitor cells. Cardiovasc Res 2008, 78:413-421.