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Volumn 50, Issue 5, 2011, Pages 910-918

Role and mechanism of subcellular Ca2+ distribution in the action of two inotropic agents with different toxicity

Author keywords

Inotropic agents; Istaroxime; Pro arrhythmia; Ryanodine receptor; SERCA2

Indexed keywords

CALCIUM; DIGOXIN; ISTAROXIME; RYANODINE RECEPTOR;

EID: 79953702223     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.02.008     Document Type: Article
Times cited : (27)

References (32)
  • 3
    • 44449084777 scopus 로고    scopus 로고
    • Hemodynamic, echocardiographic, and neurohormonal effects of istaroxime, a novel intravenous inotropic and lusitropic agent: a randomized controlled trial in patients hospitalized with heart failure
    • Gheorghiade M., Blair J.E., Filippatos G.S., Macarie C., Ruzyllo W., Korewicki J., et al. Hemodynamic, echocardiographic, and neurohormonal effects of istaroxime, a novel intravenous inotropic and lusitropic agent: a randomized controlled trial in patients hospitalized with heart failure. J Am Coll Cardiol 2008, 51:2276-2285.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 2276-2285
    • Gheorghiade, M.1    Blair, J.E.2    Filippatos, G.S.3    Macarie, C.4    Ruzyllo, W.5    Korewicki, J.6
  • 4
    • 0036827948 scopus 로고    scopus 로고
    • Pharmacological profile of the novel inotropic agent (E, Z)-3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochloride (PST2744)
    • Micheletti R., Mattera G.G., Rocchetti M., Schiavone A., Loi M.F., Zaza A., et al. Pharmacological profile of the novel inotropic agent (E, Z)-3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochloride (PST2744). J Pharmacol Exp Ther 2002, 303:592-600.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 592-600
    • Micheletti, R.1    Mattera, G.G.2    Rocchetti, M.3    Schiavone, A.4    Loi, M.F.5    Zaza, A.6
  • 5
    • 0037404402 scopus 로고    scopus 로고
    • Diverse toxicity associated with cardiac Na+/K+ pump inhibition: evaluation of electrophysiological mechanisms
    • Rocchetti M., Besana A., Mostacciuolo G., Ferrari P., Micheletti R., Zaza A. Diverse toxicity associated with cardiac Na+/K+ pump inhibition: evaluation of electrophysiological mechanisms. J Pharmacol Exp Ther 2003, 305:765-771.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 765-771
    • Rocchetti, M.1    Besana, A.2    Mostacciuolo, G.3    Ferrari, P.4    Micheletti, R.5    Zaza, A.6
  • 6
    • 15744402515 scopus 로고    scopus 로고
    • Modulation of sarcoplasmic reticulum function by Na+/K+ pump inhibitors with different toxicity: digoxin and PST2744 [(E, Z)-3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochloride]
    • Rocchetti M., Besana A., Mostacciuolo G., Micheletti R., Ferrari P., Sarkozi S., et al. Modulation of sarcoplasmic reticulum function by Na+/K+ pump inhibitors with different toxicity: digoxin and PST2744 [(E, Z)-3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochloride]. J Pharmacol Exp Ther 2005, 313:207-215.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 207-215
    • Rocchetti, M.1    Besana, A.2    Mostacciuolo, G.3    Micheletti, R.4    Ferrari, P.5    Sarkozi, S.6
  • 7
    • 53849108836 scopus 로고    scopus 로고
    • Modulation of sarcoplasmic reticulum function by PST2744 [istaroxime; (E, Z)-3-((2-aminoethoxy)imino) androstane-6,17-dione hydrochloride)] in a pressure-overload heart failure model
    • Rocchetti M., Alemanni M., Mostacciuolo G., Barassi P., Altomare C., Chisci R., et al. Modulation of sarcoplasmic reticulum function by PST2744 [istaroxime; (E, Z)-3-((2-aminoethoxy)imino) androstane-6,17-dione hydrochloride)] in a pressure-overload heart failure model. J Pharmacol Exp Ther 2008, 326:957-965.
    • (2008) J Pharmacol Exp Ther , vol.326 , pp. 957-965
    • Rocchetti, M.1    Alemanni, M.2    Mostacciuolo, G.3    Barassi, P.4    Altomare, C.5    Chisci, R.6
  • 10
    • 0031922664 scopus 로고    scopus 로고
    • Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects
    • Li L., Chu G.X., Kranias E.G., Bers D.M. Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects. Am J Physiol 1998, 43:H1335-H1347.
    • (1998) Am J Physiol , vol.43
    • Li, L.1    Chu, G.X.2    Kranias, E.G.3    Bers, D.M.4
  • 11
    • 0022521980 scopus 로고
    • Cellular basis for the species-differences in sensitivity to cardiac-glycosides (digitalis)
    • Gupta R.S., Chopra A., Stetsko D.K. Cellular basis for the species-differences in sensitivity to cardiac-glycosides (digitalis). J Cell Physiol 1986, 127:197-206.
    • (1986) J Cell Physiol , vol.127 , pp. 197-206
    • Gupta, R.S.1    Chopra, A.2    Stetsko, D.K.3
  • 12
    • 0035890307 scopus 로고    scopus 로고
    • Effects of aldosterone on transient outward K+ current density in rat ventricular myocytes
    • Benitah J.P., Perrier E., Gomez A.M., Vassort G. Effects of aldosterone on transient outward K+ current density in rat ventricular myocytes. J Physiol 2001, 537:151-160.
    • (2001) J Physiol , vol.537 , pp. 151-160
    • Benitah, J.P.1    Perrier, E.2    Gomez, A.M.3    Vassort, G.4
  • 14
    • 0027477843 scopus 로고
    • An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes
    • Varro A., Negretti N., Hester S.B., Eisner D.A. An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes. Pflugers Arch 1993, 423:158-160.
    • (1993) Pflugers Arch , vol.423 , pp. 158-160
    • Varro, A.1    Negretti, N.2    Hester, S.B.3    Eisner, D.A.4
  • 15
    • 33847058737 scopus 로고    scopus 로고
    • Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase
    • Curran J., Hinton M.J., Rios E., Bers D.M., Shannon T.R. Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase. Circ Res 2007, 100:391-398.
    • (2007) Circ Res , vol.100 , pp. 391-398
    • Curran, J.1    Hinton, M.J.2    Rios, E.3    Bers, D.M.4    Shannon, T.R.5
  • 16
    • 0037019969 scopus 로고    scopus 로고
    • Quantitative assessment of the SR Ca2+ leak-load relationship
    • Shannon T.R., Ginsburg K.S., Bers D.M. Quantitative assessment of the SR Ca2+ leak-load relationship. Circ Res 2002, 91:594-600.
    • (2002) Circ Res , vol.91 , pp. 594-600
    • Shannon, T.R.1    Ginsburg, K.S.2    Bers, D.M.3
  • 17
    • 0030821712 scopus 로고    scopus 로고
    • Regulation of current flow through ryanodine receptors by luminal Ca2+
    • Sitsapesan R., Williams A.J. Regulation of current flow through ryanodine receptors by luminal Ca2+. J Membr Biol 1997, 159:179-185.
    • (1997) J Membr Biol , vol.159 , pp. 179-185
    • Sitsapesan, R.1    Williams, A.J.2
  • 18
    • 0031751235 scopus 로고    scopus 로고
    • Regulation of cardiac muscle Ca2+ release channel by sarcoplasmic reticulum lumenal Ca2+
    • Xu L., Meissner G. Regulation of cardiac muscle Ca2+ release channel by sarcoplasmic reticulum lumenal Ca2+. Biophys J 1998, 75:2302-2312.
    • (1998) Biophys J , vol.75 , pp. 2302-2312
    • Xu, L.1    Meissner, G.2
  • 19
    • 33845575639 scopus 로고    scopus 로고
    • Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes
    • Berry R.G., Despa S., Fuller W., Bers D.M., Shattock M.J. Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes. Cardiovasc Res 2007, 73:92-100.
    • (2007) Cardiovasc Res , vol.73 , pp. 92-100
    • Berry, R.G.1    Despa, S.2    Fuller, W.3    Bers, D.M.4    Shattock, M.J.5
  • 20
    • 0033757853 scopus 로고    scopus 로고
    • The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes
    • Trafford A.W., Sibbring G.C., Diaz M.E., Eisner D.A. The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes. Cell Calcium 2000, 28:269-276.
    • (2000) Cell Calcium , vol.28 , pp. 269-276
    • Trafford, A.W.1    Sibbring, G.C.2    Diaz, M.E.3    Eisner, D.A.4
  • 21
    • 0028843314 scopus 로고
    • Kinetics of [Ca]i decline in cardiac myocytes depend on peak [Ca]i
    • Bers D.M., Berlin J.R. Kinetics of [Ca]i decline in cardiac myocytes depend on peak [Ca]i. Am J Physiol 1995, 268:C271-C277.
    • (1995) Am J Physiol , vol.268
    • Bers, D.M.1    Berlin, J.R.2
  • 22
    • 3242692393 scopus 로고    scopus 로고
    • Macromolecular complexes regulating cardiac ryanodine receptor function
    • Bers D.M. Macromolecular complexes regulating cardiac ryanodine receptor function. J Mol Cell Cardiol 2004, 37:417-429.
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 417-429
    • Bers, D.M.1
  • 24
    • 0033847506 scopus 로고    scopus 로고
    • Relative importance of SR load and cytoplasmic calcium concentration in the genesis of aftercontractions in cardiac myocytes
    • Egdell R.M., De Souza A.I., MacLeod K.T. Relative importance of SR load and cytoplasmic calcium concentration in the genesis of aftercontractions in cardiac myocytes. Cardiovasc Res 2000, 47:769-777.
    • (2000) Cardiovasc Res , vol.47 , pp. 769-777
    • Egdell, R.M.1    De Souza, A.I.2    MacLeod, K.T.3
  • 25
    • 0033843421 scopus 로고    scopus 로고
    • Sarcoplasmic reticulum Ca content, sarcolemmal Ca influx and the genesis of arrhythmias in isolated guinea-pig cardiomyocytes
    • Tweedie D., Harding S.E., MacLeod K.T. Sarcoplasmic reticulum Ca content, sarcolemmal Ca influx and the genesis of arrhythmias in isolated guinea-pig cardiomyocytes. J Mol Cell Cardiol 2000, 32:261-272.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 261-272
    • Tweedie, D.1    Harding, S.E.2    MacLeod, K.T.3
  • 26
    • 0342546511 scopus 로고    scopus 로고
    • Modulation of CICR has no maintained effect on systolic Ca2+: simultaneous measurements of sarcoplasmic reticulum and sarcolemmal Ca2+ fluxes in rat ventricular myocytes
    • Trafford A.W., Diaz M.E., Sibbring G.C., Eisner D.A. Modulation of CICR has no maintained effect on systolic Ca2+: simultaneous measurements of sarcoplasmic reticulum and sarcolemmal Ca2+ fluxes in rat ventricular myocytes. J Physiol 2000, 522(Pt 2):259-270.
    • (2000) J Physiol , vol.522 , Issue.PT 2 , pp. 259-270
    • Trafford, A.W.1    Diaz, M.E.2    Sibbring, G.C.3    Eisner, D.A.4
  • 27
    • 33846117456 scopus 로고    scopus 로고
    • Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves:threshold sarcoplasmic reticulum calcium content is required
    • Venetucci L.A., Trafford A.W., Eisner D.A. Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves:threshold sarcoplasmic reticulum calcium content is required. Circ Res 2007, 100:105-111.
    • (2007) Circ Res , vol.100 , pp. 105-111
    • Venetucci, L.A.1    Trafford, A.W.2    Eisner, D.A.3
  • 29
    • 0036838635 scopus 로고    scopus 로고
    • Positive inotropic effects of ouabain in isolated cat ventricular myocytes in sodium-free conditions
    • Nishio M., Ruch S.W., Wasserstrom J.A. Positive inotropic effects of ouabain in isolated cat ventricular myocytes in sodium-free conditions. Am J Physiol 2002, 283:H2045-H2053.
    • (2002) Am J Physiol , vol.283
    • Nishio, M.1    Ruch, S.W.2    Wasserstrom, J.A.3
  • 30
    • 33748447906 scopus 로고    scopus 로고
    • The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function
    • Altamirano J., Li Y.X., DeSantiago J., Piacentino V., Houser S.R., Bers D.M. The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function. J Physiol 2006, 575:845-854.
    • (2006) J Physiol , vol.575 , pp. 845-854
    • Altamirano, J.1    Li, Y.X.2    DeSantiago, J.3    Piacentino, V.4    Houser, S.R.5    Bers, D.M.6
  • 31
    • 40649100093 scopus 로고    scopus 로고
    • Heart failure drug digitoxin induces calcium uptake into cells by forming transmembrane calcium channels
    • Arispe N., Diaz J.C., Simakova O., Pollard H.B. Heart failure drug digitoxin induces calcium uptake into cells by forming transmembrane calcium channels. Proc Natl Acad Sci USA 2008, 105:2610-2615.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2610-2615
    • Arispe, N.1    Diaz, J.C.2    Simakova, O.3    Pollard, H.B.4
  • 32
    • 11144353634 scopus 로고    scopus 로고
    • Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias
    • Chen Y., Escoubet B., Prunier F., Amour J., Simonides W.S., Vivien B., et al. Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias. Circulation 2004, 109:1898-1903.
    • (2004) Circulation , vol.109 , pp. 1898-1903
    • Chen, Y.1    Escoubet, B.2    Prunier, F.3    Amour, J.4    Simonides, W.S.5    Vivien, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.