-
1
-
-
35548957866
-
How I treat chronic myeloid leukemia in the imatinib era
-
DOI 10.1182/blood-2007-04-038943
-
Goldman JM: How I treat chronic myeloid leukemia in the imatinib era. Blood 2007; 110:2828-2837. (Pubitemid 350006935)
-
(2007)
Blood
, vol.110
, Issue.8
, pp. 2828-2837
-
-
Goldman, J.M.1
-
2
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
DOI 10.1056/NEJMoa022457
-
O'Brien SG, Guilhot F, Larson RA, Gathmann I, Baccarani M, Cervantes F, Cornelissen JJ, Fischer T, Hochhaus A, Hughes T, Lechner K, Nielsen JL, Rousselot P, Reiffers J, Saglio G, Shepherd J, Simonsson B, Gratwohl A, Goldman JM, Kantarjian H, Taylor K, Verhoef G, Bolton AE, Capdeville R, Druker BJ: Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2003; 348: 994-1004. (Pubitemid 36302244)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.11
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
Cornelissen, J.J.7
Fischer, T.8
Hochhaus, A.9
Hughes, T.10
Lechner, K.11
Nielsen, J.L.12
Rousselot, P.13
Reiffers, J.14
Saglio, G.15
Shepherd, J.16
Simonsson, B.17
Gratwohl, A.18
Goldman, J.M.19
Kantarjian, H.20
Taylor, K.21
Verhoef, G.22
Bolton, A.E.23
Capdeville, R.24
Druker, B.J.25
more..
-
3
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
DOI 10.1056/NEJMoa062867
-
Druker BJ, Guilhot F, O'Brien SG, Gathmann I, Kantarjian H, Gattermann N, Deininger MW, Silver RT, Goldman JM, Stone RM, Cervantes F, Hochhaus A, Powell BL, Gabrilove JL, Rousselot P, Reiffers J, Cornelissen JJ, Hughes T, Agis H, Fischer T, Verhoef G, Shepherd J, Saglio G, Gratwohl A, Nielsen JL, Radich JP, Simonsson B, Taylor K, Baccarani M, So C, Letvak L, Larson RA: Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 2006; 355: 2408-2417. (Pubitemid 44903745)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.23
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
Gathmann, I.4
Kantarjian, H.5
Gattermann, N.6
Deininger, M.W.N.7
Silver, R.T.8
Goldman, J.M.9
Stone, R.M.10
Cervantes, F.11
Hochhaus, A.12
Powell, B.L.13
Gabrilove, J.L.14
Rousselot, P.15
Reiffers, J.16
Cornelissen, J.J.17
Hughes, T.18
Agis, H.19
Fischer, T.20
Verhoef, G.21
Shepherd, J.22
Saglio, G.23
Gratwohl, A.24
Nielsen, J.L.25
Radich, J.P.26
Simonsson, B.27
Taylor, K.28
Baccarani, M.29
So, C.30
Letvak, L.31
Larson, R.A.32
more..
-
4
-
-
49149111543
-
Imatinib for newly diagnosed patients with chronic myeloid leukemia: Incidence of sustained responses in an intention-to-treat analysis
-
De Lavallade H, Apperley JF, Khorashad JS, Milojkovic D, Reid AG, Bua M, Szydlo R, Olavarria E, Kaeda J, Goldman JM, Marin D: Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis. J Clin Oncol 2008; 26: 3358-3363.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3358-3363
-
-
De Lavallade, H.1
Apperley, J.F.2
Khorashad, J.S.3
Milojkovic, D.4
Reid, A.G.5
Bua, M.6
Szydlo, R.7
Olavarria, E.8
Kaeda, J.9
Goldman, J.M.10
Marin, D.11
-
5
-
-
73349122639
-
Chronic myeloid leukemia: An update of concepts and management recommendations of European Leukemia Net
-
Baccarani M, Cortes J, Pane F, Niederwieser D, Saglio G, Apperley J, Cervantes F, Deininger M, Gratwohl A, Guilhot F, Hochhaus A, Horowitz M, Hughes T, Kantarjian H, Larson R, Radich J, Simonsson B, Silver RT, Goldman J, Hehlmann R: Chronic myeloid leukemia: an update of concepts and management recommendations of European Leukemia Net. J Clin Oncol 2009; 27: 6041-6051.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6041-6051
-
-
Baccarani, M.1
Cortes, J.2
Pane, F.3
Niederwieser, D.4
Saglio, G.5
Apperley, J.6
Cervantes, F.7
Deininger, M.8
Gratwohl, A.9
Guilhot, F.10
Hochhaus, A.11
Horowitz, M.12
Hughes, T.13
Kantarjian, H.14
Larson, R.15
Radich, J.16
Simonsson, B.17
Silver, R.T.18
Goldman, J.19
Hehlmann, R.20
more..
-
6
-
-
77958595179
-
Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: An analysis from the International Randomized Study of Interferon and STI571 (IRIS)
-
Hughes TP, Hochhaus A, Branford S, Muller MC, Kaeda JS, Foroni L, Druker BJ, Guilhot F, Larson RA, O'Brien SG, Rudoltz MS, Mone M, Wehrle E, Modur V, Goldman JM, Radich JP: Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS). Blood 2010; 116: 3758-3765.
-
(2010)
Blood
, vol.116
, pp. 3758-3765
-
-
Hughes, T.P.1
Hochhaus, A.2
Branford, S.3
Muller, M.C.4
Kaeda, J.S.5
Foroni, L.6
Druker, B.J.7
Guilhot, F.8
Larson, R.A.9
O'Brien, S.G.10
Rudoltz, M.S.11
Mone, M.12
Wehrle, E.13
Modur, V.14
Goldman, J.M.15
Radich, J.P.16
-
7
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
DOI 10.1126/science.1062538
-
Gorre ME, Mohammed M, Ellwood K, Hsu N, Paquette R, Rao PN, Sawyers CL: Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001; 293:876-880. (Pubitemid 32743979)
-
(2001)
Science
, vol.293
, Issue.5531
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
Hsu, N.4
Paquette, R.5
Nagesh Rao, P.6
Sawyers, C.L.7
-
8
-
-
33644525274
-
Gene expression changes associated with progression and response in chronic myeloid leukemia
-
Radich JP, Dai H, Mao M, Oehler V, Schelter J, Druker B, Sawyers C, Shah N, Stock W, Willman CL, Friend S, Linsley PS: Gene expression changes associated with progression and response in chronic myeloid leukemia. Proc Natl Acad Sci USA 2006; 103: 2794-2799.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2794-2799
-
-
Radich, J.P.1
Dai, H.2
Mao, M.3
Oehler, V.4
Schelter, J.5
Druker, B.6
Sawyers, C.7
Shah, N.8
Stock, W.9
Willman, C.L.10
Friend, S.11
Linsley, P.S.12
-
9
-
-
77954936879
-
Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib
-
White DL, Dang P, Engler J, Frede A, Zrim S, Osborn M, Saunders VA, Manley PW, Hughes TP: Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib. J Clin Oncol 2010; 28:2761-2767.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2761-2767
-
-
White, D.L.1
Dang, P.2
Engler, J.3
Frede, A.4
Zrim, S.5
Osborn, M.6
Saunders, V.A.7
Manley, P.W.8
Hughes, T.P.9
-
10
-
-
9444282642
-
Active transport of imatinib into and out of cells: Implications for drug resistance
-
DOI 10.1182/blood-2003-12-4276
-
Thomas J, Wang L, Clark RE, Pirmohamed M: Active transport of imatinib into and out of cells: implications for drug resistance. Blood 2004; 104: 3739-3745. (Pubitemid 39564452)
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3739-3745
-
-
Thomas, J.1
Wang, L.2
Clark, R.E.3
Pirmohamed, M.4
-
11
-
-
3242775403
-
Imatinib therapy in chronic myeloid leukemia
-
DOI 10.1016/j.hoc.2004.03.014, PII S0889858804000322
-
Crossman LC, O'Brien SG: Imatinib therapy in chronic myeloid leukemia. Hematol Oncol Clin North Am 2004; 18: 605-617, viii. (Pubitemid 38969134)
-
(2004)
Hematology/Oncology Clinics of North America
, vol.18
, Issue.3
, pp. 605-617
-
-
Crossman, L.C.1
O'Brien, S.G.2
-
12
-
-
1542608328
-
Pharmacokinetics and pharmacodynamics of imatinib in a phase I trial with chronic myeloid leukemia patients
-
DOI 10.1200/JCO.2004.03.050
-
Peng B, Hayes M, Resta D, Racine-Poon A, Druker BJ, Talpaz M, Sawyers CL, Rosamilia M, Ford J, Lloyd P, Capdeville R: Pharmacokinetics and pharmacodynamics of imatinib in a phase I trial with chronic myeloid leukemia patients. J Clin Oncol 2004; 22: 935-942. (Pubitemid 41103606)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 935-942
-
-
Peng, B.1
Hayes, M.2
Resta, D.3
Racine-Poon, A.4
Druker, B.J.5
Talpaz, M.6
Sawyers, C.L.7
Rosamilia, M.8
Ford, J.9
Lloyd, P.10
Capdeville, R.11
-
13
-
-
70349329835
-
Pharmacokinetic/pharmaco-dynamic correlation and blood-level testing in imatinib therapy for chronic myeloid leukemia
-
Cortes JE, Egorin MJ, Guilhot F, Molimard M, Mahon FX: Pharmacokinetic/pharmaco-dynamic correlation and blood-level testing in imatinib therapy for chronic myeloid leukemia. Leukemia 2009; 23: 1537-1544.
-
(2009)
Leukemia
, vol.23
, pp. 1537-1544
-
-
Cortes, J.E.1
Egorin, M.J.2
Guilhot, F.3
Molimard, M.4
Mahon, F.X.5
-
14
-
-
77952467377
-
Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib
-
Marin D, Bazeos A, Mahon FX, Eliasson L, Milojkovic D, Bua M, Apperley JF, Szydlo R, Desai R, Kozlowski K, Paliompeis C, Latham V, Foroni L, Molimard M, Reid A, Rezvani K, de Lavallade H, Guallar C, Goldman J, Khorashad JS: Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib. J Clin Oncol 2010; 28:2381-2388.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2381-2388
-
-
Marin, D.1
Bazeos, A.2
Mahon, F.X.3
Eliasson, L.4
Milojkovic, D.5
Bua, M.6
Apperley, J.F.7
Szydlo, R.8
Desai, R.9
Kozlowski, K.10
Paliompeis, C.11
Latham, V.12
Foroni, L.13
Molimard, M.14
Reid, A.15
Rezvani, K.16
De Lavallade, H.17
Guallar, C.18
Goldman, J.19
Khorashad, J.S.20
more..
-
15
-
-
1642494654
-
Absolute Bioavailability of Imatinib (Glivec®) Orally versus Intravenous Infusion
-
DOI 10.1177/0091270003262101
-
Peng B, Dutreix C, Mehring G, Hayes MJ, Ben-Am M, Seiberling M, Pokorny R, Capdeville R, Lloyd P: Absolute bioavailability of imatinib (Glivec) orally versus intravenous infusion. J Clin Pharmacol 2004; 44: 158-162. (Pubitemid 38114314)
-
(2004)
Journal of Clinical Pharmacology
, vol.44
, Issue.2
, pp. 158-162
-
-
Peng, B.1
Dutreix, C.2
Mehring, G.3
Hayes, M.J.4
Ben-Am, M.5
Seiberling, M.6
Pokorny, R.7
Cupdeville, R.8
Lloyd, P.9
-
16
-
-
24944581623
-
Metabolism and disposition of imatinib mesylate in healthy volunteers
-
DOI 10.1124/dmd.105.004283
-
Gschwind HP, Pfaar U, Waldmeier F, Zollinger M, Sayer C, Zbinden P, Hayes M, Pokorny R, Seiberling M, Ben-Am M, Peng B, Gross G: Metabolism and disposition of imatinib mesylate in healthy volunteers. Drug Metab Dispos 2005; 33:1503-1512. (Pubitemid 41323999)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.10
, pp. 1503-1512
-
-
Gschwind, H.-P.1
Pfaar, U.2
Waldmeier, F.3
Zollinger, M.4
Sayer, C.5
Zbinden, P.6
Hayes, M.7
Pokorny, R.8
Seiberling, M.9
Ben-Am, M.10
Peng, B.11
Gross, G.12
-
17
-
-
12144290456
-
Pharmacokinetics and cellular uptake of imatinib and its main metabolite CGP74588
-
DOI 10.1007/s00280-003-0741-6
-
Le Coutre P, Kreuzer KA, Pursche S, Bonin M, Leopold T, Baskaynak G, Dorken B, Ehninger G, Ottmann O, Jenke A, Bornhauser M, Schleyer E: Pharmacokinetics and cellular uptake of imatinib and its main metabolite CGP74588. Cancer Chemother Pharmacol 2004; 53: 313-323. (Pubitemid 38392356)
-
(2004)
Cancer Chemotherapy and Pharmacology
, vol.53
, Issue.4
, pp. 313-323
-
-
Le Coutre, P.1
Kreuzer, K.-A.2
Pursche, S.3
Bonin, M.V.4
Leopold, T.5
Baskaynak, G.6
Dorken, B.7
Ehninger, G.8
Ottmann, O.9
Jenke, A.10
Bornhauser, M.11
Schleyer, E.12
-
18
-
-
70349655281
-
A therapeutic drug monitoring algorithm for refining the imatinib trough level obtained at different sampling times
-
Wang Y, Chia YL, Nedelman J, Schran H, Mahon FX, Molimard M: A therapeutic drug monitoring algorithm for refining the imatinib trough level obtained at different sampling times. Ther Drug Monit 2009; 31: 579-584.
-
(2009)
Ther Drug Monit
, vol.31
, pp. 579-584
-
-
Wang, Y.1
Chia, Y.L.2
Nedelman, J.3
Schran, H.4
Mahon, F.X.5
Molimard, M.6
-
19
-
-
10744231436
-
Effects of imatinib mesylate (ST1571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome P450 3A4 substrate, in patients with chronic myeloid leukaemia
-
DOI 10.1038/sj.bjc.6601152
-
O'Brien SG, Meinhardt P, Bond E, Beck J, Peng B, Dutreix C, Mehring G, Milosavljev S, Huber C, Capdeville R, Fischer T: Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. Br J Cancer 2003; 89:1855-1859. (Pubitemid 37533259)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.10
, pp. 1855-1859
-
-
O'Brien, S.G.1
Meinhardt, P.2
Bond, E.3
Beck, J.4
Peng, B.5
Dutreix, C.6
Mehring, G.7
Milosavljev, S.8
Huber, C.9
Capdeville, R.10
Fischer, T.11
-
20
-
-
37549055433
-
Influence of CYP3A4 inhibition on the steady-state pharmacokinetics of imatinib
-
Van Erp NP, Gelderblom H, Karlsson MO, Li J, Zhao M, Ouwerkerk J, Nortier JW, Guchelaar HJ, Baker SD, Sparreboom A: Influence of CYP3A4 inhibition on the steady-state pharmacokinetics of imatinib. Clin Cancer Res 2007; 13: 7394-7400.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7394-7400
-
-
Van Erp, N.P.1
Gelderblom, H.2
Karlsson, M.O.3
Li, J.4
Zhao, M.5
Ouwerkerk, J.6
Nortier, J.W.7
Guchelaar, H.J.8
Baker, S.D.9
Sparreboom, A.10
-
21
-
-
77953934202
-
CYYP3A activity influences imatinib response in patients with chronic myeloid leukemia: A pilot study on in vivo CYP3A activity
-
Green H, Skoglund K, Rommel F, Mirghani RA, Lotfi K: CYYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity. Eur J Clin Pharmacol 2010; 66:383-386.
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 383-386
-
-
Green, H.1
Skoglund, K.2
Rommel, F.3
Mirghani, R.A.4
Lotfi, K.5
-
22
-
-
39149099201
-
Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: A study by the national cancer institute organ dysfunction working group
-
DOI 10.1200/JCO.2007.13.3819
-
Gibbons J, Egorin MJ, Ramanathan RK, Fu P, Mulkerin DL, Shibata S, Takimoto CH, Mani S, Lo Russo PA, Grem JL, Pavlick A, Lenz HJ, Flick SM, Reynolds S, Lagattuta TF, Parise RA, Wang Y, Murgo AJ, Ivy SP, Remick SC: Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: a study by the National Cancer Institute organ dysfunction working group. J Clin Oncol 2008; 26: 570-576. (Pubitemid 351264350)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 570-576
-
-
Gibbons, J.1
Egorin, M.J.2
Ramanathan, R.K.3
Fu, P.4
Mulkerin, D.L.5
Shibata, S.6
Takimoto, C.H.M.7
Mani, S.8
LoRusso, P.A.9
Grem, J.L.10
Pavlick, A.11
Lenz, H.-J.12
Flick, S.M.13
Reynolds, S.14
Lagattuta, T.F.15
Parise, R.A.16
Wang, Y.17
Murgo, A.J.18
Ivy, S.P.19
Remick, S.C.20
more..
-
23
-
-
49649092002
-
Interaction of imatinib with human organic ion carriers
-
Hu S, Franke RM, Filipski KK, Hu C, Orwick SJ, de Bruijn EA, Burger H, Baker SD, Sparreboom A: Interaction of imatinib with human organic ion carriers. Clin Cancer Res 2008; 14: 3141-3148.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3141-3148
-
-
Hu, S.1
Franke, R.M.2
Filipski, K.K.3
Hu, C.4
Orwick, S.J.5
De Bruijn, E.A.6
Burger, H.7
Baker, S.D.8
Sparreboom, A.9
-
24
-
-
33846911973
-
Imatinib concentrations in human milk
-
DOI 10.1182/blood-2006-08-039545
-
Gambacorti-Passerini CB, Tornaghi L, Marangon E, Franceschino A, Pogliani EM, D'Incalci M, Zucchetti M: Imatinib concentrations in human milk. Blood 2007; 109: 1790. (Pubitemid 46239616)
-
(2007)
Blood
, vol.109
, Issue.4
, pp. 1790
-
-
Gambacorti-Passerini, C.B.1
Tornaghi, L.2
Marangon, E.3
Franceschino, A.4
Pogliani, E.M.5
D'Incalci, M.6
Zucchetti, M.7
-
25
-
-
34147174980
-
Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia
-
DOI 10.1182/blood-2006-07-036012
-
Picard S, Titier K, Etienne G, Teilhet E, Ducint D, Bernard MA, Lassalle R, Marit G, Reiffers J, Begaud B, Moore N, Molimard M, Mahon FX: Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia. Blood 2007; 109: 3496-3499. (Pubitemid 46572540)
-
(2007)
Blood
, vol.109
, Issue.8
, pp. 3496-3499
-
-
Picard, S.1
Titier, K.2
Etienne, G.3
Teilhet, E.4
Ducint, D.5
Bernard, M.-A.6
Lassalle, R.7
Marit, G.8
Reiffers, J.9
Begaud, B.10
Moore, N.11
Molimard, M.12
Mahon, F.-X.13
-
26
-
-
43249083718
-
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: A subanalysis of the iris study
-
Larson RA, Druker BJ, Guilhot F, O'Brien SG, Riviere GJ, Krahnke T, Gathmann I, Wang Y: Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the iris study. Blood 2008; 111:4022-4028.
-
(2008)
Blood
, vol.111
, pp. 4022-4028
-
-
Larson, R.A.1
Druker, B.J.2
Guilhot, F.3
O'Brien, S.G.4
Riviere, G.J.5
Krahnke, T.6
Gathmann, I.7
Wang, Y.8
-
27
-
-
57049115901
-
Cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia are correlated with Sokal risk scores and duration of therapy but not trough imatinib plasma levels
-
Forrest DL, Trainor S, Brinkman RR, Barnett MJ, Hogge DE, Nevill TJ, Shepherd JD, Nantel SH, Toze CL, Sutherland HJ, Song KW, Lavoie JC, Power MM, Abou-Mourad Y, Smith CA: Cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia are correlated with Sokal risk scores and duration of therapy but not trough imatinib plasma levels. Leuk Res 2009; 33: 271-275.
-
(2009)
Leuk Res
, vol.33
, pp. 271-275
-
-
Forrest, D.L.1
Trainor, S.2
Brinkman, R.R.3
Barnett, M.J.4
Hogge, D.E.5
Nevill, T.J.6
Shepherd, J.D.7
Nantel, S.H.8
Toze, C.L.9
Sutherland, H.J.10
Song, K.W.11
Lavoie, J.C.12
Power, M.M.13
Abou-Mourad, Y.14
Smith, C.A.15
-
28
-
-
43649107281
-
Relationship of imatinib-free plasma levels and target genotype with efficacy and tolerability
-
DOI 10.1038/sj.bjc.6604355, PII 6604355
-
Widmer N, Decosterd LA, Leyvraz S, Duchosal MA, Rosselet A, Debiec-Rychter M, Csajka C, Biollaz J, Buclin T: Relationship of imatinib-free plasma levels and target genotype with efficacy and tolerability. Br J Cancer 2008; 98:1633-1640. (Pubitemid 351684684)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.10
, pp. 1633-1640
-
-
Widmer, N.1
Decosterd, L.A.2
Leyvraz, S.3
Duchosal, M.A.4
Rosselet, A.5
Debiec-Rychter, M.6
Csajka, C.7
Biollaz, J.8
Buclin, T.9
-
29
-
-
68849113721
-
Drug monitoring of imatinib levels in patients undergoing therapy for chronic myeloid leukaemia: Comparing plasma levels of responders and non-responders
-
Singh N, Kumar L, Meena R, Velpandian T: Drug monitoring of imatinib levels in patients undergoing therapy for chronic myeloid leukaemia: comparing plasma levels of responders and non-responders. Eur J Clin Pharmacol 2009; 65:545-549.
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 545-549
-
-
Singh, N.1
Kumar, L.2
Meena, R.3
Velpandian, T.4
-
30
-
-
78449312021
-
Correlation between imatinib pharmacokinetics and clinical response in Japanese patients with chronic-phase chronic myeloid leukemia
-
Takahashi N, Wakita H, Miura M, Scott SA, Nishii K, Masuko M, Sakai M, Maeda Y, Ishige K, Kashimura M, Fujikawa K, Fukazawa M, Katayama T, Monma F, Narita M, Urase F, Furukawa T, Miyazaki Y, Katayama N, Sawada K: Correlation between imatinib pharmacokinetics and clinical response in Japanese patients with chronic-phase chronic myeloid leukemia. Clin Pharmacol Ther 2010; 88: 809-813.
-
(2010)
Clin Pharmacol Ther
, vol.88
, pp. 809-813
-
-
Takahashi, N.1
Wakita, H.2
Miura, M.3
Scott, S.A.4
Nishii, K.5
Masuko, M.6
Sakai, M.7
Maeda, Y.8
Ishige, K.9
Kashimura, M.10
Fujikawa, K.11
Fukazawa, M.12
Katayama, T.13
Monma, F.14
Narita, M.15
Urase, F.16
Furukawa, T.17
Miyazaki, Y.18
Katayama, N.19
Sawada, K.20
more..
-
31
-
-
33750735723
-
Pharmacokinetic-pharmacodynamic relationships of imatinib and its main metabolite in patients with advanced gastrointestinal stromal tumors
-
DOI 10.1158/1078-0432.CCR-05-2596
-
Delbaldo C, Chatelut E, Re M, Deroussent A, Seronie-Vivien S, Jambu A, Berthaud P, Le Cesne A, Blay JY, Vassal G: Pharmacokinetic-pharmacodynamic relationships of imatinib and its main metabolite in patients with advanced gastrointestinal stromal tumors. Clin Cancer Res 2006; 12:6073-6078. (Pubitemid 44703771)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.20 PART 1
, pp. 6073-6078
-
-
Delbaldo, C.1
Chatelut, E.2
Re, M.3
Deroussent, A.4
Seronie-Vivien, S.5
Jambu, A.6
Berthaud, P.7
Le Cesne, A.8
Blay, J.-Y.9
Vassal, G.10
-
32
-
-
67349233062
-
Sixyear follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia
-
Hochhaus A, O'Brien SG, Guilhot F, Druker BJ, Branford S, Foroni L, Goldman JM, Muller MC, Radich JP, Rudoltz M, Mone M, Gathmann I, Hughes TP, Larson RA: Sixyear follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia. Leu kemia 2009; 23: 1054-1061.
-
(2009)
Leu Kemia
, vol.23
, pp. 1054-1061
-
-
Hochhaus, A.1
O'Brien, S.G.2
Guilhot, F.3
Druker, B.J.4
Branford, S.5
Foroni, L.6
Goldman, J.M.7
Muller, M.C.8
Radich, J.P.9
Rudoltz, M.10
Mone, M.11
Gathmann, I.12
Hughes, T.P.13
Larson, R.A.14
-
33
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
DOI 10.1056/NEJM200104053441401
-
Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, Lydon NB, Kantarjian H, Capdeville R, Ohno-Jones S, Sawyers CL: Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leu kemia. N Engl J Med 2001; 344: 1031-1037. (Pubitemid 32267972)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.14
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
34
-
-
70350442594
-
High-dose imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: High rates of rapid cytogenetic and molecular responses
-
Cortes JE, Kantarjian HM, Goldberg SL, Powell BL, Giles FJ, Wetzler M, Akard L, Burke JM, Kerr R, Saleh M, Salvado A, McDougall K, Albitar M, Radich J: High-dose imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: high rates of rapid cytogenetic and molecular responses. J Clin Oncol 2009; 27:4754-4759.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4754-4759
-
-
Cortes, J.E.1
Kantarjian, H.M.2
Goldberg, S.L.3
Powell, B.L.4
Giles, F.J.5
Wetzler, M.6
Akard, L.7
Burke, J.M.8
Kerr, R.9
Saleh, M.10
Salvado, A.11
McDougall, K.12
Albitar, M.13
Radich, J.14
-
35
-
-
0037085785
-
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
-
DOI 10.1182/blood.V99.6.1928
-
Talpaz M, Silver RT, Druker BJ, Goldman JM, Gambacorti-Passerini C, Guilhot F, Schiffer CA, Fischer T, Deininger MW, Lennard AL, Hochhaus A, Ottmann OG, Gratwohl A, Baccarani M, Stone R, Tura S, Mahon FX, Fernandes-Reese S, Gathmann I, Capdeville R, Kantarjian HM, Sawyers CL: Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood 2002; 99: 1928-1937. (Pubitemid 34525471)
-
(2002)
Blood
, vol.99
, Issue.6
, pp. 1928-1937
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.J.3
Goldman, J.M.4
Gambacorti-Passerini, C.5
Guilhot, F.6
Schiffer, C.A.7
Fischer, T.8
Deininger, M.W.N.9
Lennard, A.L.10
Hochhaus, A.11
Ottmann, O.G.12
Gratwohl, A.13
Baccarani, M.14
Stone, R.15
Tura, S.16
Mahon, F.-X.17
Fernandes-Reese, S.18
Gathmann, I.19
Capdeville, R.20
Kantarjian, H.M.21
Sawyers, C.L.22
more..
-
36
-
-
0042563130
-
Effects of lower dose of imatinib to CML patients
-
DOI 10.1016/S0145-2126(03)00101-2
-
Horikoshi A, Takei K, Sawada S: Effects of lower dose of imatinib to CML patients. Leuk Res 2003; 27:1167. (Pubitemid 36960038)
-
(2003)
Leukemia Research
, vol.27
, Issue.12
, pp. 1167
-
-
Horikoshi, A.1
Takei, K.2
Sawada, S.3
-
37
-
-
38749103513
-
Reduced dose of imatinib for patients with chronic myeloid leukemia and low body surface area
-
DOI 10.1159/000111777
-
Park SJ, Choi IK, Seo HY, Sung HJ, Park KH, Kim SJ, Oh SC, Seo JH, Choi CW, Kim BS, Shin SW, Kim YH, Kim JS: Reduced dose of imatinib for patients with chronic myeloid leukemia and low body surface area. Acta Haematol 2007; 118:219-221. (Pubitemid 351182634)
-
(2007)
Acta Haematologica
, vol.118
, Issue.4
, pp. 219-221
-
-
Park, S.J.1
Choi, I.K.2
Seo, H.Y.3
Sung, H.J.4
Park, K.H.5
Kim, S.J.6
Oh, S.C.7
Seo, J.H.8
Choi, C.W.9
Kim, B.S.10
Shin, S.W.11
Kim, Y.H.12
Kim, J.S.13
-
38
-
-
55549127592
-
Multicenter prospective trial evaluating the tolerability of imatinib for Japanese patients with chronic myelogenous leukemia in the chronic phase: Does body weight matter?
-
Kanda Y, Okamoto S, Tauchi T, Kizaki M, Inokuchi K, Yabe M, Yokoyama K, Ito Y, Kimura Y, Higashihara M, Bessho M, Ando K, Chiba S, Kurokawa M, Oshimi K, Dan K, Ohyashiki K, Ikeda Y: Multicenter prospective trial evaluating the tolerability of imatinib for Japanese patients with chronic myelogenous leukemia in the chronic phase: does body weight matter? Am J Hematol 2008; 83: 835-839.
-
(2008)
Am J Hematol
, vol.83
, pp. 835-839
-
-
Kanda, Y.1
Okamoto, S.2
Tauchi, T.3
Kizaki, M.4
Inokuchi, K.5
Yabe, M.6
Yokoyama, K.7
Ito, Y.8
Kimura, Y.9
Higashihara, M.10
Bessho, M.11
Ando, K.12
Chiba, S.13
Kurokawa, M.14
Oshimi, K.15
Dan, K.16
Ohyashiki, K.17
Ikeda, Y.18
-
39
-
-
67649218742
-
Long-term efficacy of imatinib in a practical setting is correlated with imatinib trough concentration that is influenced by body size: A report by the Nagasaki CML study group
-
Sakai M, Miyazaki Y, Matsuo E, Moriuchi Y, Hata T, Fukushima T, Imaizumi Y, Imanishi D, Taguchi J, Iwanaga M, Tsushima H, Inoue Y, Takasaki Y, Tsuchiya T, Komoda M, Ando K, Horio K, Moriwaki Y, Tominaga S, Itonaga H, Nagai K, Tsukasaki K, Tsutsumi C, Sawayama Y, Yamasaki R, Ogawa D, Kawaguchi Y, Ikeda S, Yoshida S, Onimaru Y, Tawara M, Atogami S, Koida S, Joh T, Yamamura M, Matsuo Y, Soda H, Nonaka H, Jinnai I, Kuriyama K, Tomonaga M: Long-term efficacy of imatinib in a practical setting is correlated with imatinib trough concentration that is influenced by body size: a report by the Nagasaki CML study group. Int J Hematol 2009; 89:319-325.
-
(2009)
Int J Hematol
, vol.89
, pp. 319-325
-
-
Sakai, M.1
Miyazaki, Y.2
Matsuo, E.3
Moriuchi, Y.4
Hata, T.5
Fukushima, T.6
Imaizumi, Y.7
Imanishi, D.8
Taguchi, J.9
Iwanaga, M.10
Tsushima, H.11
Inoue, Y.12
Takasaki, Y.13
Tsuchiya, T.14
Komoda, M.15
Ando, K.16
Horio, K.17
Moriwaki, Y.18
Tominaga, S.19
Itonaga, H.20
Nagai, K.21
Tsukasaki, K.22
Tsutsumi, C.23
Sawayama, Y.24
Yamasaki, R.25
Ogawa, D.26
Kawaguchi, Y.27
Ikeda, S.28
Yoshida, S.29
Onimaru, Y.30
Tawara, M.31
Atogami, S.32
Koida, S.33
Joh, T.34
Yamamura, M.35
Matsuo, Y.36
Soda, H.37
Nonaka, H.38
Jinnai, I.39
Kuriyama, K.40
Tomonaga, M.41
more..
-
40
-
-
67749101106
-
Relationship between an effective dose of imatinib, body surface area, and trough drug levels in patients with chronic myeloid leukemia
-
Kawaguchi T, Hamada A, Hirayama C, Nakashima R, Nambu T, Yamakawa Y, Watanabe H, Horikawa K, Mitsuya H, Saito H: Relationship between an effective dose of imatinib, body surface area, and trough drug levels in patients with chronic myeloid leukemia. Int J Hematol 2009; 89:642-648.
-
(2009)
Int J Hematol
, vol.89
, pp. 642-648
-
-
Kawaguchi, T.1
Hamada, A.2
Hirayama, C.3
Nakashima, R.4
Nambu, T.5
Yamakawa, Y.6
Watanabe, H.7
Horikawa, K.8
Mitsuya, H.9
Saito, H.10
-
41
-
-
58249137409
-
Effect of antacid on imatinib absorption
-
Sparano BA, Egorin MJ, Parise RA, Walters J, Komazec KA, Redner RL, Beumer JH: Effect of antacid on imatinib absorption. Cancer Chemother Pharmacol 2009; 63:525-528.
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 525-528
-
-
Sparano, B.A.1
Egorin, M.J.2
Parise, R.A.3
Walters, J.4
Komazec, K.A.5
Redner, R.L.6
Beumer, J.H.7
-
42
-
-
70049097234
-
Effect of a proton pump inhibitor on the pharmacokinetics of imatinib
-
Egorin MJ, Shah DD, Christner SM, Yerk MA, Komazec KA, Appleman LR, Redner RL, Miller BM, Beumer JH: Effect of a proton pump inhibitor on the pharmacokinetics of imatinib. Br J Clin Pharmacol 2009; 68: 370-374.
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 370-374
-
-
Egorin, M.J.1
Shah, D.D.2
Christner, S.M.3
Yerk, M.A.4
Komazec, K.A.5
Appleman, L.R.6
Redner, R.L.7
Miller, B.M.8
Beumer, J.H.9
-
43
-
-
0442313672
-
Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects
-
DOI 10.1007/s00280-003-0722-9
-
Bolton AE, Peng B, Hubert M, Krebs-Brown A, Capdeville R, Keller U, Seiberling M: Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects. Cancer Chemother Pharmacol 2004; 53: 102-106. (Pubitemid 38186987)
-
(2004)
Cancer Chemotherapy and Pharmacology
, vol.53
, Issue.2
, pp. 102-106
-
-
Bolton, A.E.1
Peng, B.2
Hubert, M.3
Krebs-Brown, A.4
Capdeville, R.5
Keller, U.6
Seiberling, M.7
-
44
-
-
7044245637
-
The influence of St. John's wort on the pharmacokinetics and protein binding of imatinib mesylate
-
DOI 10.1592/phco.24.16.1508.50958
-
Smith P, Bullock JM, Booker BM, Haas CE, Berenson CS, Jusko WJ: The influence of St John's wort on the pharmacokinetics and protein binding of imatinib mesylate. Pharmacotherapy 2004; 24:1508-1514. (Pubitemid 39426346)
-
(2004)
Pharmacotherapy
, vol.24
, Issue.11
, pp. 1508-1514
-
-
Smith, P.1
-
45
-
-
4744338886
-
Effect of St John's wort on imatinib mesylate pharmacokinetics
-
DOI 10.1016/j.clpt.2004.06.007, PII S0009923604002334
-
Frye RF, Fitzgerald SM, Lagattuta TF, Hruska MW, Egorin MJ: Effect of St John's wort on imatinib mesylate pharmacokinetics. Clin Pharmacol Ther 2004; 76:323-329. (Pubitemid 39313122)
-
(2004)
Clinical Pharmacology and Therapeutics
, vol.76
, Issue.4
, pp. 323-329
-
-
Frye, R.F.1
Fitzgerald, S.M.2
Lagattuta, T.F.3
Hruska, M.W.4
Egorin, M.J.5
-
46
-
-
4644287353
-
Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects
-
DOI 10.1007/s00280-004-0832-z
-
Dutreix C, Peng B, Mehring G, Hayes M, Capdeville R, Pokorny R, Seiberling M: Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects. Cancer Chemother Pharmacol 2004; 54:290-294. (Pubitemid 39304422)
-
(2004)
Cancer Chemotherapy and Pharmacology
, vol.54
, Issue.4
, pp. 290-294
-
-
Dutreix, C.1
Peng, B.2
Mehring, G.3
Hayes, M.4
Capdeville, R.5
Pokorny, R.6
Seiberling, M.7
-
47
-
-
0033055995
-
Drug interactions with tobacco smoking. An update
-
DOI 10.2165/00003088-199936060-00004
-
Zevin S, Benowitz NL: Drug interactions with tobacco smoking: an update. Clin Pharmacokinet 1999; 36:425-438. (Pubitemid 29317490)
-
(1999)
Clinical Pharmacokinetics
, vol.36
, Issue.6
, pp. 425-438
-
-
Zevin, S.1
Benowitz, N.L.2
-
48
-
-
58149340537
-
Effect of cigarette smoking on imatinib in patients in the soft tissue and bone sarcoma group of the EORTC
-
Van Erp N, Gelderblom H, van Glabbeke M, van Oosterom A, Verweij J, Guchelaar HJ, Debiec-Rychter M, Peng B, Blay JY, Judson I: Effect of cigarette smoking on imatinib in patients in the soft tissue and bone sarcoma group of the EORTC. Clin Cancer Res 2008; 14:8308-8313.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8308-8313
-
-
Van Erp, N.1
Gelderblom, H.2
Van Glabbeke, M.3
Van Oosterom, A.4
Verweij, J.5
Guchelaar, H.J.6
Debiec-Rychter, M.7
Peng, B.8
Blay, J.Y.9
Judson, I.10
-
49
-
-
39149100687
-
Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of liver dysfunction: A study by the national cancer institute organ dysfunction working group
-
DOI 10.1200/JCO.2007.11.0304
-
Ramanathan RK, Egorin MJ, Takimoto CH, Remick SC, Doroshow JH, Lo Russo PA, Mulkerin DL, Grem JL, Hamilton A, Murgo AJ, Potter DM, Belani CP, Hayes MJ, Peng B, Ivy SP: Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of liver dysfunction: a study by the National Cancer Institute organ dysfunction working group. J Clin Oncol 2008; 26: 563-569. (Pubitemid 351264349)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 563-569
-
-
Ramanathan, R.K.1
Egorin, M.J.2
Takimoto, C.H.M.3
Remick, S.C.4
Doroshow, J.H.5
LoRusso, P.A.6
Mulkerin, D.L.7
Grem, J.L.8
Hamilton, A.9
Murgo, A.J.10
Potter, D.M.11
Belani, C.P.12
Hayes, M.J.13
Peng, B.14
Ivy, S.P.15
-
50
-
-
21744449067
-
Population pharmacokinetics of imatinib mesylate in patients with chronic-phase chronic myeloid leukaemia: Results of a phase III study
-
DOI 10.1111/j.1365-2125.2005.02372.x
-
Schmidli H, Peng B, Riviere GJ, Capdeville R, Hensley M, Gathmann I, Bolton AE, Racine-Poon A: Population pharmacokinetics of imatinib mesylate in patients with chronic-phase chronic myeloid leukaemia: results of a phase III study. Br J Clin Pharmacol 2005; 60: 35-44. (Pubitemid 40942779)
-
(2005)
British Journal of Clinical Pharmacology
, vol.60
, Issue.1
, pp. 35-44
-
-
Schmidli, H.1
Peng, B.2
Riviere, G.-J.3
Capdeville, R.4
Hensley, M.5
Gathmann, I.6
Bolton, A.E.7
Racine-Poon, A.8
-
51
-
-
23244433963
-
Pharmacokinetics of imatinib mesylate in end stage renal disease. A case study
-
DOI 10.1007/s00280-005-1031-2
-
Pappas P, Karavasilis V, Briasoulis E, Pavlidis N, Marselos M: Pharmacokinetics of imatinib mesylate in end stage renal disease: a case study. Cancer Chemother Pharmacol 2005; 56: 358-360. (Pubitemid 41095398)
-
(2005)
Cancer Chemotherapy and Pharmacology
, vol.56
, Issue.4
, pp. 358-360
-
-
Pappas, P.1
Karavasilis, V.2
Briasoulis, E.3
Pavlidis, N.4
Marselos, M.5
-
52
-
-
77951922479
-
Cross-sectional study of imatinib plasma trough levels in patients with advanced gastrointestinal stromal tumors: Impact of gastrointestinal resection on exposure to imatinib
-
Yoo C, Ryu MH, Kang BW, Yoon SK, Ryoo BY, Chang HM, Lee JL, Beck MY, Kim TW, Kang YK: Cross-sectional study of imatinib plasma trough levels in patients with advanced gastrointestinal stromal tumors: impact of gastrointestinal resection on exposure to imatinib. J Clin Oncol 2010; 28:1554-1559.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1554-1559
-
-
Yoo, C.1
Ryu, M.H.2
Kang, B.W.3
Yoon, S.K.4
Ryoo, B.Y.5
Chang, H.M.6
Lee, J.L.7
Beck, M.Y.8
Kim, T.W.9
Kang, Y.K.10
-
53
-
-
33745085275
-
OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): Reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib
-
DOI 10.1182/blood-2005-11-4687
-
White DL, Saunders VA, Dang P, Engler J, Zannettino AC, Cambareri AC, Quinn SR, Manley PW, Hughes TP: OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. Blood 2006; 108:697-704. (Pubitemid 44061372)
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 697-704
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
Engler, J.4
Zannettino, A.C.W.5
Cambareri, A.C.6
Quinn, S.R.7
Manley, P.W.8
Hughes, T.P.9
-
54
-
-
38349193809
-
Expression of the uptake drug transporter HOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia
-
Wang L, Giannoudis A, Lane S, Williamson P, Pirmohamed M, Clark RE: Expression of the uptake drug transporter HOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. Clin Pharmacol Ther 2008; 83: 258-264.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 258-264
-
-
Wang, L.1
Giannoudis, A.2
Lane, S.3
Williamson, P.4
Pirmohamed, M.5
Clark, R.E.6
-
55
-
-
24344482346
-
Clinical pharmacokinetics of imatinib
-
DOI 10.2165/00003088-200544090-00001
-
Peng B, Lloyd P, Schran H: Clinical pharmacokinetics of imatinib. Clin Pharmacokinet 2005; 44: 879-894. (Pubitemid 41252840)
-
(2005)
Clinical Pharmacokinetics
, vol.44
, Issue.9
, pp. 879-894
-
-
Peng, B.1
Lloyd, P.2
Schran, H.3
-
56
-
-
0033382294
-
Cytochrome P450 3A. Ontogeny and drug disposition
-
De Wildt SN, Kearns GL, Leeder JS, van den Anker JN: Cytochrome p450 3A: ontogeny and drug disposition. Clin Pharmacokinet 1999; 37: 485-505. (Pubitemid 30032252)
-
(1999)
Clinical Pharmacokinetics
, vol.37
, Issue.6
, pp. 485-505
-
-
De Wildt, S.N.1
Kearns, G.L.2
Leeder, J.S.3
Van Den Anker, J.N.4
-
57
-
-
0037131879
-
Genetic contribution to variable human CYP3A-mediated metabolism
-
DOI 10.1016/S0169-409X(02)00066-2, PII S0169409X02000662
-
Lamba JK, Lin YS, Schuetz EG, Thummel KE: Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev 2002; 54:1271-1294. (Pubitemid 35284253)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.10
, pp. 1271-1294
-
-
Lamba, J.K.1
Lin, Y.S.2
Schuetz, E.G.3
Thummel, K.E.4
-
58
-
-
33746741049
-
Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib
-
DOI 10.1016/j.clpt.2006.05.003, PII S0009923606001731
-
Gardner ER, Burger H, van Schaik RH, van Oosterom AT, de Bruijn EA, Guetens G, Prenen H, de Jong FA, Baker SD, Bates SE, Figg WD, Verweij J, Sparreboom A, Nooter K: Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib. Clin Pharmacol Ther 2006; 80: 192-201. (Pubitemid 44160695)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.80
, Issue.2
, pp. 192-201
-
-
Gardner, E.R.1
Burger, H.2
Van Schaik, R.H.3
Van Oosterom, A.T.4
De Bruijn, E.A.5
Guetens, G.6
Prenen, H.7
De Jong, F.A.8
Baker, S.D.9
Bates, S.E.10
Figg, W.D.11
Verweij, J.12
Sparreboom, A.13
Nooter, K.14
-
59
-
-
34250676807
-
Imatinib disposition and ABCB1 (MDR1, P-glycoprotein) genotype
-
DOI 10.1038/sj.clpt.6100201, PII 6100201
-
Gurney H, Wong M, Balleine RL, Rivory LP, McLachlan AJ, Hoskins JM, Wilcken N, Clarke CL, Mann GJ, Collins M, Delforce SE, Lynch K, Schran H: Imatinib disposition and ABCB1 (MDR1, P-glycoprotein) genotype. Clin Pharmacol Ther 2007; 82: 33-40. (Pubitemid 46944197)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.82
, Issue.1
, pp. 33-40
-
-
Gurney, H.1
Wong, M.2
Balleine, R.L.3
Rivory, L.P.4
McLachlan, A.J.5
Hoskins, J.M.6
Wilcken, N.7
Clarke, C.L.8
Mann, G.J.9
Collins, M.10
Delforce, S.-E.11
Lynch, K.12
Schran, H.13
-
60
-
-
78649522748
-
Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia
-
Takahashi N, Miura M, Scott SA, Kagaya H, Kameoka Y, Tagawa H, Saitoh H, Fujishima N, Yoshioka T, Hirokawa M, Sawada K: Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia. J Hum Genet 2010; 55:731-737.
-
(2010)
J Hum Genet
, vol.55
, pp. 731-737
-
-
Takahashi, N.1
Miura, M.2
Scott, S.A.3
Kagaya, H.4
Kameoka, Y.5
Tagawa, H.6
Saitoh, H.7
Fujishima, N.8
Yoshioka, T.9
Hirokawa, M.10
Sawada, K.11
-
61
-
-
25144450089
-
Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps
-
Burger H, van Tol H, Brok M, Wiemer EA, de Bruijn EA, Guetens G, de Boeck G, Sparreboom A, Verweij J, Nooter K: Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps. Cancer Biol Ther 2005; 4:747-752. (Pubitemid 41351174)
-
(2005)
Cancer Biology and Therapy
, vol.4
, Issue.7
, pp. 747-752
-
-
Burger, H.1
Van Tol, H.2
Brok, M.3
Wiemer, E.A.C.4
De Bruijn, E.A.5
Guetens, G.6
De Boeck, G.7
Sparreboom, A.8
Verweij, J.9
Nooter, K.10
-
62
-
-
7244232706
-
Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump
-
DOI 10.1182/blood-2004-04-1398
-
Burger H, van Tol H, Boersma AW, Brok M, Wiemer EA, Stoter G, Nooter K: Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump. Blood 2004; 104:2940-2942. (Pubitemid 39434984)
-
(2004)
Blood
, vol.104
, Issue.9
, pp. 2940-2942
-
-
Burger, H.1
Van Tol, H.2
Boersma, A.W.M.3
Brok, M.4
Wiemer, E.A.C.5
Stoter, G.6
Nooter, K.7
-
63
-
-
2442638937
-
High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter
-
DOI 10.1124/mol.65.6.1485
-
Ozvegy-Laczka C, Hegedus T, Varady G, Ujhelly O, Schuetz JD, Varadi A, Keri G, Orfi L, Nemet K, Sarkadi B: High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Mol Pharmacol 2004; 65:1485-1495. (Pubitemid 38668306)
-
(2004)
Molecular Pharmacology
, vol.65
, Issue.6
, pp. 1485-1495
-
-
Ozvegy-Laczka, C.1
Hegedus, T.2
Varady, G.3
Ujhelly, O.4
Schuetz, J.D.5
Varadi, A.6
Keri, G.7
Orfi, L.8
Nemet, K.9
Sarkadi, B.10
-
64
-
-
34249669336
-
Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells
-
DOI 10.1038/sj.leu.2404638, PII 2404638
-
Brendel C, Scharenberg C, Dohse M, Robey RW, Bates SE, Shukla S, Ambudkar SV, Wang Y, Wennemuth G, Burchert A, Boudriot U, Neubauer A: Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells. Leukemia 2007; 21:1267-1275. (Pubitemid 46831816)
-
(2007)
Leukemia
, vol.21
, Issue.6
, pp. 1267-1275
-
-
Brendel, C.1
Scharenberg, C.2
Dohse, M.3
Robey, R.W.4
Bates, S.E.5
Shukla, S.6
Ambudkar, S.V.7
Wang, Y.8
Wennemuth, G.9
Burchert, A.10
Boudriot, U.11
Neubauer, A.12
-
65
-
-
77954892297
-
Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib
-
Dohse M, Scharenberg C, Shukla S, Robey RW, Volkmann T, Deeken JF, Brendel C, Ambudkar SV, Neubauer A, Bates SE: Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib. Drug Metab Dispos 2010; 38:1371-1380.
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 1371-1380
-
-
Dohse, M.1
Scharenberg, C.2
Shukla, S.3
Robey, R.W.4
Volkmann, T.5
Deeken, J.F.6
Brendel, C.7
Ambudkar, S.V.8
Neubauer, A.9
Bates, S.E.10
-
66
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC: Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 1987; 84:7735-7738.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
67
-
-
23944475903
-
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin
-
DOI 10.1124/mol.105.014019
-
Hirano M, Maeda K, Matsushima S, Nozaki Y, Kusuhara H, Sugiyama Y: Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin. Mol Pharmacol 2005; 68:800-807. (Pubitemid 41206035)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.3
, pp. 800-807
-
-
Hirano, M.1
Maeda, K.2
Matsushima, S.3
Nozaki, Y.4
Kusuhara, H.5
Sugiyama, Y.6
-
68
-
-
33747884712
-
Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males
-
DOI 10.1016/j.cca.2006.05.010, PII S000989810600266X
-
Zhang W, Yu BN, He YJ, Fan L, Li Q, Liu ZQ, Wang A, Liu YL, Tan ZR, Fen J, Huang YF, Zhou HH: Role of BCRP 421C → A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males. Clin Chim Acta 2006; 373: 99-103. (Pubitemid 44292182)
-
(2006)
Clinica Chimica Acta
, vol.373
, Issue.1-2
, pp. 99-103
-
-
Zhang, W.1
Yu, B.-N.2
He, Y.-J.3
Fan, L.4
Li, Q.5
Liu, Z.-Q.6
Wang, A.7
Liu, Y.-L.8
Tan, Z.-R.9
Fen, J.10
Huang, Y.-F.11
Zhou, H.-H.12
-
69
-
-
58149214370
-
Population pharmacokinetics and pharmacogenetics of imatinib in children and adults
-
Petain A, Kattygnarath D, Azard J, Chatelut E, Delbaldo C, Geoerger B, Barrois M, Seronie-Vivien S, Le Cesne A, Vassal G: Population pharmacokinetics and pharmacogenetics of imatinib in children and adults. Clin Cancer Res 2008; 14: 7102-7109.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7102-7109
-
-
Petain, A.1
Kattygnarath, D.2
Azard, J.3
Chatelut, E.4
Delbaldo, C.5
Geoerger, B.6
Barrois, M.7
Seronie-Vivien, S.8
Le Cesne, A.9
Vassal, G.10
-
70
-
-
56149118632
-
Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences
-
Choi MK, Song IS: Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences. Drug Metab Pharmacokinet 2008; 23: 243-253.
-
(2008)
Drug Metab Pharmacokinet
, vol.23
, pp. 243-253
-
-
Choi, M.K.1
Song, I.S.2
-
71
-
-
0030915085
-
Cloning and functional expression of a human liver organic cation transporter
-
Zhang L, Dresser MJ, Gray AT, Yost SC, Terashita S, Giacomini KM: Cloning and functional expression of a human liver organic cat ion transpor ter. Mol Pharmacol 1997; 51: 913-921. (Pubitemid 27249124)
-
(1997)
Molecular Pharmacology
, vol.51
, Issue.6
, pp. 913-921
-
-
Zhang, L.1
Dresser, M.J.2
Gray, A.T.3
Yost, S.C.4
Terashita, S.5
Giacomini, K.M.6
-
72
-
-
0031846917
-
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa)
-
Zhang L, Schaner ME, Giacomini KM: Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). J Pharmacol Exp Ther 1998; 286: 354-361. (Pubitemid 28318011)
-
(1998)
Journal of Pharmacology and Experimental Therapeutics
, vol.286
, Issue.1
, pp. 354-361
-
-
Zhang, L.1
Schaner, M.E.2
Giacomini, K.M.3
|