Pharmacokinetic/pharmacodynamic correlation and blood-level testing in imatinib therapy for chronic myeloid leukemia

Leukemia

Volumn 23, Issue 9, 2009, Pages 1537-1544

  Cortes, J E ^a   Egorin, M J ^b   Guilhot, F ^c   Molimard, M ^d   Mahon, F X ^e  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c POITIERS UNIVERSITY HOSPITAL   (France)

^d UNIVERSITÉ DE BORDEAUX   (France)

^e BORDEAUX UNIVERSITY HOSPITAL   (France)

Author keywords

Blood level testing; Chronic myeloid leukemia; Imatinib; Pharmacodynamics; Pharmacokinetics; Tyrosine kinase inhibitors

Indexed keywords

ANTINEOPLASTIC AGENT; IMATINIB; OROSOMUCOID; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

CHRONIC MYELOID LEUKEMIA; DRUG INTERACTION; HUMAN; INTESTINE ABSORPTION; METABOLISM; PATIENT COMPLIANCE; PROTEIN BINDING; REVIEW; TREATMENT FAILURE;

ANTINEOPLASTIC AGENTS; DRUG INTERACTIONS; HUMANS; INTESTINAL ABSORPTION; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MEDICATION ADHERENCE; OROSOMUCOID; PIPERAZINES; PROTEIN BINDING; PYRIMIDINES; TREATMENT FAILURE;

EID: 70349329835     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2009.88     Document Type: Review

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