Carcinogenic heavy metals, As3+ and Cr6+, increase affinity of nuclear mono-ubiquitinated annexin A1 for DNA containing 8-oxo-guanosine, and promote translesion DNA synthesis

Toxicology and Applied Pharmacology

Volumn 252, Issue 2, 2011, Pages 159-164

  Hirata, Aiko ^a   Corcoran, George B ^a   Hirata, Fusao ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

Annexin A1; As3+ and Cr6+; Carcinogenic heavy metals; DNA damage; Mono ubiquitination; Mutagenesis; Repair

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARSENIC; CALCIUM; CHROMIUM; DOUBLE STRANDED DNA; GUANOSINE DERIVATIVE; LIPOCORTIN 1; MAGNESIUM; OLIGONUCLEOTIDE; SINGLE STRANDED DNA;

ARTICLE; BINDING AFFINITY; CARCINOGENICITY; DNA DAMAGE; DNA SYNTHESIS; GENE MUTATION; HUMAN; HUMAN CELL; LYMPHOMA CELL; OXIDATION;

ANIMALS; ANNEXIN A1; ARSENICALS; CELL LINE, TUMOR; CELL NUCLEUS; CHROMIUM COMPOUNDS; DNA; DNA DAMAGE; DNA REPAIR; GUANOSINE; METALS, HEAVY; PROTEIN BINDING; RATS; UBIQUITINATION;

EID: 79953690476     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.01.022     Document Type: Article

References (25)

1. Avkin S., Livneh Z. Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative DNA lesion 8-oxoguanine in human cells. Mutat. Res. 2002, 510:81-90.
2. Blobel G., Potter V.R. Nuclei from rat liver: isolation method that combines purity with high yield. Science 1966, 154:1662-1665.
3. Galanis A., Karapetsas A., Sadaltzopoulos R. Metal-induced carcinogenesis, oxidative stress and hypoxia signalling. Mutat. Res. 2009, 674:31-35.
4. Gerke V., Moss S.E. Annexins: from structure to function. Physiol. Rev. 2002, 82:331-371.
5. Harrigan J.A., Opresko P.L., von Kobbe C., Kedar P.S., Prasad R., Wilson S.H., Bohr V.A. The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity. J. Biol. Chem. 2003, 278:22686-22695.
6. Hirata F. Annexins (lipocortins). Encyclopedia of Immunology 1998, 111-115. Academic Press Ltd. 2nd ed. I.M. Roitt, P.J. Delves (Eds.).
7. Hirata A., Hirata F. Lipocortin (annexin) I heterotetramer binds to purine RNA and pyrimidine DNA. Biochem. Biophys. Res. Commun. 1999, 265:200-204.
8. 2+. Biochem. Biophys. Res. Commun. 2002, 291:205-209.
9. Hirata F., Matsuda K., Notsu Y., Hattori T., DelCarmine R. Phosphorylation at tyrosine residue of lipomodulin in mitogen-stimulated murine thymocytes. Proc. Natl Acad. Sci. USA 1984, 81:4717-4721.
10. 2+ for DNA binding and annealing activities of mono-ubiquitinated annexin A1 homodimer. Toxicol. Appl. Pharmacol. 2010, 248:45-51.
11. Hirata F., Thibodeau L.M., Hirata A. Uabiquitination and SUMOylation of annexin A1 and its helicase activities. Biochim. Biophys. Acta (General Subject) 2010, 1800:899-905.
12. Jindal H.K., Vishwanatha J.K. Purification and characterization of primer recognition proteins from HeLa cells. Biochemistry 1990, 29:4767-4773.
13. Kasprzak K.S. Possible role of oxidative damage in metal-induced carcinogenesis. Cancer Investig. 1995, 13:411-430.
14. Lim L.H., Pervaiz S. Annexin I: the new face of an old molecule. FASEB J. 2007, 21:968-975.
15. Lin S., Hickey R.J., Malkas L.H. The isolation of a DNA synthesome from human leukemia cells. Leuk. Res. 1997, 21:501-512.
16. Lin C.Y., Jeng Y.M., Chou H.Y., Hsu H.C., Yuan R.H., Chiang C.P., Kuo M.Y. Nuclear lodalization of annexin A1 is a prognostic factor in oral squamous cell carcinoma. J. Surg. Oncol. 2008, 97:544-550.
17. Liu Y., Wang H.X., Lu N., Mao Y.S., Liu F., Wang Y., Zhang H.R., Wang K., Wu M., Zhao X.H. Translocation of annexin I from cellular membrane to the nuclear membrane in human esophageal squamous cell carcinoma. World J. Gastroenterol. 2003, 9:645-649.
18. Maier A., Schumann B.L., Chang X., Talaska G., Puga A. Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity. Mutat. Res. 2002, 517:101-111.
19. Masaki T., Tokuda M., Ohnishi M., Watanabe S., Fujishima T., Miyamoto K., Itano T., Matsui H., Arima K., Shirai M., Maeba T., Sogawa K., Konishi R., Taniguchi K., Hatanaka Y., Hatase O., Nishioka M. Enhanced expression of the protein kinase substrate annexin in human hepatocellular carcinoma. Hepatology 1996, 24:72-81.
20. O'Brien T.J., Witcher P., Brooks B., Patierno S.R. DNA polymerase Τ is essential for hexavalent chronium-induced mutagenesis. Mutat. Res. 2009, 663:77-83.
21. Pagès V., Fuchs R.P. How DNA lesions are turned into mutations within cells?. Oncogene 2002, 21:8957-8966.
22. Rhee H.J., Kim G.Y., Huh J.W., Kim S.W., Na D.S. Annexin I is a stress protein induced by heat, oxidative stress and a sulfhydryl-reactive agent. Eur. J. Biochem. 2000, 267:3220-3225.
23. Sacre S.M., Moss S.E. Intracellular localization of endothelial cell annexins is differentially regulated by oxidative stress. Exp. Cell Res. 2002, 274:254-263.
24. Sekowski J.W., Malkas L.H., Wei Y., Hickey R.J. Mercuric ion inhibits the activity and fidelity of the human cell DNA synthesome. Toxicol. Appl. Pharmacol. 1997, 145:268-276.
25. Skouteris G.G., Schröder C.H. The hepatocyte growth factor receptor kinase-mediated phosphorylation of lipocortin-I transduces the proliferating signal of the hepatocyte growth factor. J. Biol. Chem. 1996, 271:27266-27273.