Optimization of process conditions for preparing an iron-polysaccharide complex by response surface methodology

Chemical and Biochemical Engineering Quarterly

Volumn 25, Issue 1, 2011, Pages 75-81

  Zhang, Y Y ^a   Liu, J H ^a  

^a QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Drug substance; Iron polysaccharide complex; Process conditions; Response surface methodology

Indexed keywords

AQUEOUS SOLUTIONS; BASIC SOLUTIONS; CENTRAL COMPOSITE DESIGNS; DRUG SUBSTANCES; ETHANOL PRECIPITATION; FERRIC HYDROXIDE; INDUSTRIAL-SCALE PRODUCTION; LOW SPEED; OPTIMAL CONDITIONS; OPTIMIZED PROCESS; PROCESS CONDITION; PROCESS CONDITIONS; QUADRATIC POLYNOMIAL; RESPONSE SURFACE METHODOLOGY; SCALE-UP EXPERIMENT; SEPARATION AND PURIFICATION; SYNTHETIC PROCESS;

CENTRIFUGATION; ETHANOL; OPTIMIZATION; POLYNOMIALS; PRECIPITATION (CHEMICAL); SODIUM; SURFACE PROPERTIES;

IRON COMPOUNDS;

EID: 79953680154     PISSN: 03529568     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Hudson, J. Q., Comstock, T. J., Clin. Ther. 23 (2001) 1637.
2. Kane, R. C., Curr. Ther. Res. 64 (2003) 263.
3. Ma, Y., Liu, M., Yue, X.-L., Zha, Z.-B., Dai, Z.-F., Int. J. Biol. Macromol. 46 (2010) 109.
4. Coe, E. M., Bowen, L. H., Speer, J. A., Bereman, R. D., J. Inorg. Biochem. 57 (1995) 287.
5. Coe, E. M., Bowen, L. H., Speer, J. A., Wang, Z., Sayers, D. E., Bereman, R. D., J. Inorg. Biochem. 58 (1995) 269.
6. Zhang, Y.-Y., Liu, J.-H., Su, F., Lui, Y.-T., Li, J.-F., Curr. Ther. Res. 70 (2009) 104.
7. Zheng, J., Yue, X.-L., Dai, Z.-F., Wang, Y., Liu, S.-Q., Yan, X.-F., Acta Biomater. 5 (2009) 1499.
8. Raghuveer, T. S., McGuire, E. M., Martin, S. M., Wanger, B. A., Rebouché, C. J., Buettner, G. R., Widness, J. A., Pediatr. Res. 52 (2002) 964.
9. Kenneth, O. M., Chandrakant, R. J., Process for preparing an iron-saccharide complex, USP3821192, 1974.
10. Bereman, R. D., Berg, K. A., Inorg. Chim. A. 155 (1989) 183.
11. Somsook, E., Hinsin, D., Buakhrong, P., Teanchai, R., Mophan, N., Pohmakotr, M., Shiowatana, J., Carbohyd. Polym. 61 (2005) 281.
12. International Conference on Harmonization (ICH), Technical requirements for the registration of pharmaceuticals for human use, Q3C: impurities: guideline for residual solvents, 1997, Step 4.
13. Montgomery, D. C., Design and Analysis of Experiments, 5th ed., John Wiley and Sons, New York, USA, 2001.
14. Azargohar, R., Dalai, A. K., Micropor. Mesopor. Mat. 85 (2005) 219.
15. Liu, J.-H., Zhang, Y.-Y., Xia, Y.-M., Su, F., Chem. Biochem. Eng. Q. 24 (2010) 203.
16. Guo, X., Zou, X., Sun, M., Carbohyd. Polym. 80 (2010) 344.
17. Sun, Y.-X., Li, Y.-J., Li, M.-Q., Tong, H.-B., Yang, X.-D., Liu, J.-C., Carbohyd. Polym. 75 (2009) 575.
18. Celebi, N., Yildiz, N., Demir, A. S., Calimli, A., J. Supercrit. Fluids 47 (2008) 227.
19. Yuan, Y., Gao, Y.-X., Mao, L., Zhao, J., Food Chem. 107 (2008) 1300.
20. Sipos, P., Stpierre, T. G., Tombacz, E., Webb, J., J. Inorg. Biochem. 58 (1995) 129.