Association between high plasma levels of hepatocyte growth factor and progression of radiographic damage in the joints of patients with rheumatoid arthritis

Arthritis and Rheumatism

Volumn 63, Issue 3, 2011, Pages 662-669

  Grandaunet, Berit ^a   Syversen, Silje W ^b   Hoff, Mari ^c   Sundan, Anders ^a   Haugeberg, Glenn ^d   Van Der Heijde, Desirée ^e   Kvien, Tore K ^b   Standal, Therese ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b DIAKONHJEMMET HOSPITAL   (Norway)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^d Sørlandet Hospital   (Norway)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DICKKOPF 1 PROTEIN; SCATTER FACTOR;

ADULT; ARTICLE; BLOOD SAMPLING; DEMOGRAPHY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HAND RADIOGRAPHY; HUMAN; INTERMETHOD COMPARISON; JOINT INJURY; JOINT RADIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PLASMA; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RHEUMATOID ARTHRITIS; SHARP VAN DER HEIJDE SCORE;

ADULT; AGED; ARTHRITIS, RHEUMATOID; ARTHROGRAPHY; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HEPATOCYTE GROWTH FACTOR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JOINTS; LINEAR MODELS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; OSTEOBLASTS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES;

EID: 79953678662     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.30163     Document Type: Article

References (34)

1. Walsh NC, Gravallese EM. Bone remodeling in rheumatic disease: a question of balance. Immunol Rev 2010;233:301-12.
2. Walsh NC, Reinwald S, Manning CA, Condon KW, Iwata K, Burr DB, et al. Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis. J Bone Miner Res 2009; 24:1572-85.
3. Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, et al. Dickkopf-1 is a master regulator of joint remodeling. Nat Med 2007;13:156-63.
4. Zwerina J, Tuerk B, Redlich K, Smolen JS, Schett G. Imbalance of local bone metabolism in inflammatory arthritis and its reversal upon tumor necrosis factor blockade: direct analysis of bone turnover in murine arthritis. Arthritis Res Ther 2006;8:R22.
5. Yudoh K, Matsuno H, Osada R, Nakazawa F, Katayama R, Kimura T. Decreased cellular activity and replicative capacity of osteoblastic cells isolated from the periarticular bone of rheumatoid arthritis patients compared with osteoarthritis patients. Arthritis Rheum 2000;43:2178-88.
6. Gori F, Hofbauer LC, Dunstan CR, Spelsberg TC, Khosla S, Riggs BL. The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated. Endocrinology 2000;141:4768-76. (Pubitemid 32055158)
7. Atkins GJ, Kostakis P, Pan B, Farrugia A, Gronthos S, Evdokiou A, et al. RANKL expression is related to the differentiation state of human osteoblasts. J Bone Miner Res 2003;18:1088-98. (Pubitemid 37294947)
8. Yaccoby S. Osteoblastogenesis and tumor growth in myeloma. Leuk Lymphoma 2010;51:213-20.
9. Milat F, Ng KW. Is Wnt signalling the final common pathway leading to bone formation? Mol Cell Endocrinol 2009;310:52-62.
10. Canalis E. Growth factor control of bone mass. J Cell Biochem 2009;108:769-77.
11. Gazzerro E, Canalis E. Bone morphogenetic proteins and their antagonists. Rev Endocr Metab Disord 2006;7:51-65. (Pubitemid 46044349)
12. Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, Barlogie B, et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 2003;349:2483-94. (Pubitemid 38010074)
13. Qiang YW, Chen Y, Stephens O, Brown N, Chen B, Epstein J, et al. Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma. Blood 2008;112:196-207.
14. Standal T, Abildgaard N, Fagerli UM, Stordal B, Hjertner O, Borset M, et al. HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma. Blood 2007;109:3024-30. (Pubitemid 46482103)
15. Garnero P, Tabassi NC, Voorzanger-Rousselot N. Circulating Dickkopf-1 and radiological progression in patients with early rheumatoid arthritis treated with etanercept. J Rheumatol 2008; 35:2313-5.
16. Feuerherm AJ, Borset M, Seidel C, Sundan A, Leistad L, Ostensen M, et al. Elevated levels of osteoprotegerin (OPG) and hepatocyte growth factor (HGF) in rheumatoid arthritis. Scand J Rheumatol 2001;30:229-34. (Pubitemid 32762861)
17. Yukioka K, Inaba M, Furumitsu Y, Yukioka M, Nishino T, Goto H, et al. Levels of hepatocyte growth factor in synovial fluid and serum of patients with rheumatoid arthritis and release of hepatocyte growth factor by rheumatoid synovial fluid cells. J Rheumatol 1994;21:2184-9.
18. Smedstad LM, Kvien TK, Moum T, Vaglum P. Life events, psychosocial factors, and demographic variables in early rheumatoid arthritis: relations to one-year changes in functional disability. J Rheumatol 1995;22:2218-25.
19. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24. (Pubitemid 18091653)
20. Smedstad LM, Moum T, Guillemin F, Kvien TK, Finch MB, Suurmeijer TP, et al. Correlates of functional disability in early rheumatoid arthritis: a cross-sectional study of 706 patients in four European countries. Br J Rheumatol 1996;35:746-51.
21. Odegard S, Landewe R, van der Heijde D, Kvien TK, Mowinckel P, Uhlig T. Association of early radiographic damage with impaired physical function in rheumatoid arthritis: a ten-year, longitudinal observational study in 238 patients. Arthritis Rheum 2006;54:68-75. (Pubitemid 43122188)
22. Syversen SW, Goll GL, van der Heijde D, Landewe R, Gaarder PI, Odegard S, et al. Cartilage and bone biomarkers in rheumatoid arthritis: prediction of 10-year radiographic progression. J Rheumatol 2009;36:266-72.
23. Hoff M, Haugeberg G, Odegard S, Syversen S, Landewe R, van der Heijde D, et al. Cortical hand bone loss after 1 year in early rheumatoid arthritis predicts radiographic hand joint damage at 5-year and 10-year follow-up. Ann Rheum Dis 2009;68:324-9.
24. Van der Heijde DM, van Riel PL, Nuver-Zwart IH, Gribnau FW, van de Putte LB. Effects of hydroxychloroquine and sulphasalazine on progression of joint damage in rheumatoid arthritis. Lancet 1989;1:1036-8. (Pubitemid 19123055)
25. Bau B, McKenna LA, Soeder S, Fan Z, Pecht A, Aigner T. Hepatocyte growth factor/scatter factor is not a potent regulator of anabolic and catabolic gene expression in adult human articular chondrocytes. Biochem Biophys Res Commun 2004;316:984-90. (Pubitemid 38369049)
26. Guevremont M, Martel-Pelletier J, Massicotte F, Tardif G, Pelletier JP, Ranger P, et al. Human adult chondrocytes express hepatocyte growth factor (HGF) isoforms but not HgF: potential implication of osteoblasts on the presence of HGF in cartilage. J Bone Miner Res 2003;18:1073-81. (Pubitemid 37294945)
27. Adamopoulos IE, Xia Z, Lau YS, Athanasou NA. Hepatocyte growth factor can substitute for M-CSF to support osteoclastogenesis. Biochem Biophys Res Commun 2006;350:478-83. (Pubitemid 44498660)
28. Cao Y, Liu Q. Therapeutic targets of multiple angiogenic factors for the treatment of cancer and metastasis. Adv Cancer Res 2007; 97:203-24. (Pubitemid 46528989)
29. Koch AE, Halloran MM, Hosaka S, Shah MR, Haskell CJ, Baker SK, et al. Hepatocyte growth factor: a cytokine mediating endothelial migration in inflammatory arthritis. Arthritis Rheum 1996; 39:1566-75. (Pubitemid 26314991)
30. Paleolog EM. Angiogenesis in rheumatoid arthritis. Arthritis Res 2002;4 Suppl 3:S81-90.
31. Nagashima M, Hasegawa J, Kato K, Yamazaki J, Nishigai K, Ishiwata T, et al. Hepatocyte growth factor (HGF), HGF activator, and c-Met in synovial tissues in rheumatoid arthritis and osteoarthritis. J Rheumatol 2001;28:1772-8. (Pubitemid 32726922)
32. kB-but not JNK-dependent mechanism. Am J Physiol Cell Physiol 2008;294: C675-82. (Pubitemid 351468685)
33. Daoussis D, Liossis SN, Solomou EE, Tsanaktsi A, Bounia K, Karampetsou M, et al. Evidence that Dkk-1 is dysfunctional in ankylosing spondylitis. Arthritis Rheum 2010;62:150-8.
34. Syversen SW, Landewe R, van der Heijde D, Bathon JM, Boers M, Bykerk VP, et al. Testing of the OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage in rheumatoid arthritis: a systematic literature search on 5 candidate biomarkers. J Rheumatol 2009;36:1769-84.