메뉴 건너뛰기




Volumn 102, Issue 2, 2011, Pages 255-260

Determination of the methylation status of MGMT in different regions within glioblastoma multiforme

Author keywords

Brain tumor; GBM; Glioblastoma; Heterogeneity; Homogeneity; Methylation; MGMT

Indexed keywords

PARAFFIN;

EID: 79953677481     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-010-0307-5     Document Type: Article
Times cited : (47)

References (21)
  • 4
    • 0037086285 scopus 로고    scopus 로고
    • Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase
    • Wick W, Wick A, Schulz JB, Dichgans J, Rodemann HP, Weller M (2002) Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase. Cancer Res 62:1915-1919 (Pubitemid 34408522)
    • (2002) Cancer Research , vol.62 , Issue.6 , pp. 1915-1919
    • Wick, W.1    Wick, A.2    Schulz, J.B.3    Dichgans, J.4    Rodemann, H.P.5    Weller, M.6
  • 6
    • 0030479125 scopus 로고    scopus 로고
    • Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
    • Liu L, Markowitz S, Gerson SL (1996) Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Res 56:5375-5379 (Pubitemid 27011367)
    • (1996) Cancer Research , vol.56 , Issue.23 , pp. 5375-5379
    • Liu, L.1    Markowitz, S.2    Gerson, S.L.3
  • 7
    • 0034667383 scopus 로고    scopus 로고
    • Apoptosis induced by DNA damage O6-methylguanine is bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent
    • Ochs K, Kaina B (2000) Apoptosis induced by DNA damage O6-methylguanine is bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent. Cancer Res 60:5815-5824
    • (2000) Cancer Res , vol.60 , pp. 5815-5824
    • Ochs, K.1    Kaina, B.2
  • 8
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E et al (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343:1350-1354
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3
  • 11
    • 38649088636 scopus 로고    scopus 로고
    • Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma
    • Parkinson JF, Wheeler HR, Clarkson A et al (2008) Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma. J Neurooncol 87:71-78
    • (2008) J Neurooncol , vol.87 , pp. 71-78
    • Parkinson, J.F.1    Wheeler, H.R.2    Clarkson, A.3
  • 12
    • 0036898005 scopus 로고    scopus 로고
    • Effect of fixatives and tissue processing on the content and integrity of nucleic acids
    • Srinivasan M, Sedmak D, Jewell S (2002) Effect of fixatives and tissue processing on the content and integrity of nucleic acids. Am J Pathol 161:1961-1971 (Pubitemid 35434840)
    • (2002) American Journal of Pathology , vol.161 , Issue.6 , pp. 1961-1971
    • Srinivasan, M.1    Sedmak, D.2    Jewell, S.3
  • 13
    • 38449091221 scopus 로고    scopus 로고
    • A comparative study of the quality of DNA obtained from fresh frozen and formalin-fixed decalcified paraffin-embedded bone marrow trephine biopsy specimens using two different methods
    • DOI 10.1136/jcp.2006.045294
    • Talaulikar D, Gray JX, Shadbolt B, McNiven M, Dahlstrom JE (2008) A comparative study of the quality of DNA obtained from fresh frozen and formalin-fixed decalcified paraffin-embedded bone marrow trephine biopsy specimens using two different methods. J Clin Pathol 61:119-123 (Pubitemid 351158237)
    • (2008) Journal of Clinical Pathology , vol.61 , Issue.1 , pp. 119-123
    • Talaulikar, D.1    Gray, J.X.2    Shadbolt, B.3    McNiven, M.4    Dahlstrom, J.E.5
  • 14
    • 70350314719 scopus 로고    scopus 로고
    • The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas
    • Cao VT, Jung TY, Jung S et al (2009) The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas. Neurosurgery 65:866-875
    • (2009) Neurosurgery , vol.65 , pp. 866-875
    • Cao, V.T.1    Jung, T.Y.2    Jung, S.3
  • 16
    • 67651246847 scopus 로고    scopus 로고
    • Prognostic significance of the immunohistochemical expression of O(6)-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas
    • Nakagawa T, Ido K, Sakuma T, Takeuchi H, Sato K, Kubota T (2009) Prognostic significance of the immunohistochemical expression of O(6)-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas. Neuropathology 29:379-388
    • (2009) Neuropathology , vol.29 , pp. 379-388
    • Nakagawa, T.1    Ido, K.2    Sakuma, T.3    Takeuchi, H.4    Sato, K.5    Kubota, T.6
  • 17
    • 54849188000 scopus 로고    scopus 로고
    • Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas
    • Yachi K, Watanabe T, Ohta T et al (2008) Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas. Int J Oncol 33:469-475
    • (2008) Int J Oncol , vol.33 , pp. 469-475
    • Yachi, K.1    Watanabe, T.2    Ohta, T.3
  • 18
    • 57149111930 scopus 로고    scopus 로고
    • Reliability and reproducibility of PCR-based testing of O6-methylguanine-DNA methyltransferase gene (MGMT) promoter methylation status in formalin-fixed and paraffin-embedded neurosurgical biopsy specimens
    • Preusser M, Elezi L, Hainfellner JA (2008) Reliability and reproducibility of PCR-based testing of O6-methylguanine-DNA methyltransferase gene (MGMT) promoter methylation status in formalin-fixed and paraffin-embedded neurosurgical biopsy specimens. Clin Neuropathol 27:388-390
    • (2008) Clin Neuropathol , vol.27 , pp. 388-390
    • Preusser, M.1    Elezi, L.2    Hainfellner, J.A.3
  • 19
    • 75149166496 scopus 로고    scopus 로고
    • MGMT promoter methylation in malignant gliomas: Ready for personalized medicine?
    • Wller M, Stupp R, Reifenberger G et al (2010) MGMT promoter methylation in malignant gliomas: ready for personalized medicine? Nat Rev Neurol 6:39-51
    • (2010) Nat Rev Neurol , vol.6 , pp. 39-51
    • Wller, M.1    Stupp, R.2    Reifenberger, G.3
  • 20
    • 79953721539 scopus 로고    scopus 로고
    • Cilengitide for subjects with newly diagnosed glioblastoma multiforme and methylated mgmt gene promoter - a multicenter, open-label, controlled phase III study, testing cilengitide in combination with standard treatment (temozolomide with concomitant radiation therapy, followed by temozolomide maintenance therapy) versus standard treatment alone. Accessed 16 Feb 2010
    • Cilengitide for subjects with newly diagnosed glioblastoma multiforme and methylated mgmt gene promoter - a multicenter, open-label, controlled phase III study, testing cilengitide in combination with standard treatment (temozolomide with concomitant radiation therapy, followed by temozolomide maintenance therapy) versus standard treatment alone. http://www.clinicaltrials.gov/ct2/ show/NCT00689221. Accessed 16 Feb 2010
  • 21
    • 79953721835 scopus 로고    scopus 로고
    • Cilengitide in subjects with newly diagnosed glioblastoma multiforme and unmethylated mgmt gene promoter - a multicenter, open-label phase ii study, investigating two cilengitide regimens in combination with standard treatment (temozolomide with concomitant radiation therapy, followed by temozolomide maintenance therapy). Accessed 16 Feb 2010
    • Cilengitide in subjects with newly diagnosed glioblastoma multiforme and unmethylated mgmt gene promoter - a multicenter, open-label phase ii study, investigating two cilengitide regimens in combination with standard treatment (temozolomide with concomitant radiation therapy, followed by temozolomide maintenance therapy). http://www.clinicaltrials.gov/ct2/show/NCT00813943. Accessed 16 Feb 2010


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.