Role of cardiac isoform of alpha-2 macroglobulin in diabetic myocardium

Molecular and Cellular Biochemistry

Volumn 350, Issue 1-2, 2011, Pages 229-235

  Soman, Sowmya ^a   Manju, C S ^a   Rauf, Arun A ^a   Indira, M ^a   Rajamanickam, C ^a  

^a UNIVERSITY OF KERALA   (India)

Author keywords

182 kDa protein; Antioxidant enzymes; Cardiac hypertrophy; Diabetes mellitus; Real time PCR

Indexed keywords

ALPHA 2 MACROGLOBULIN; ALPHA ACTIN; ANTIOXIDANT; MYOSIN LIGHT CHAIN 2; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; FEMALE; GENE EXPRESSION; HEART MUSCLE; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; NONHUMAN; PROTEIN PURIFICATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SYSTEMATIC REVIEW; UPREGULATION;

ACTINS; ALPHA-MACROGLOBULINS; ANIMALS; CARDIOMEGALY; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; FEMALE; GENE EXPRESSION; MYOCARDIUM; MYOSIN HEAVY CHAINS; OXIDATIVE STRESS; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ANIMALIA; RATTUS;

EID: 79953673208     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0702-4     Document Type: Article

References (23)

1. Garg MC, Ojha S, Bansal DD (1996) Antioxidant status of streptozotocin diabetic rats. Indian J Exp Biol 34:264-266 (Pubitemid 26247847)
2. Boueiz A, Damarla M, Hassoun P (2008) Xanthine oxidoreductase in respiratory and cardiovascular disorders. Am J Physiol 294:L830-L840
3. Adeghate E (2004) Molecular and cellular basis of the aetiology and management of diabetic cardiomyopathy: a short review. E Mol Cell Biochem 261(1-2):187-191
4. Mariappan M, Selvamurugan N, Rajamanickam C (1994) Purification and characterization of a high molecular weight protein induced in rat serum during the development of cardiac hypertrophy. Arch Biochem Biophys 281(2):287-297
5. Rajamanickam C, Sakthivel S, Babu GJ, Lottspeich F, Kadenbach B (2001) Cardiac isoform of alpha-2 macroglobin, a novel serum protein, may induce cardiac hypertrophy in rats. Basic Res Cardiol 96:23-33 (Pubitemid 32120064)
6. Rajan S, Radhakrishnan J, Rajamanickam C (2003) Direct injection and expression in vivo of full- length cDNA of the cardiac isoform of alpha-2 macroglobulin induces cardiac hypertrophy in the rat heart. Basic Res Cardiol 98:39-49 (Pubitemid 36163516)
7. Annapoorani P, Dhandapany PS, Sadayappan S, Ramasamy S, Rathinavel A, Selvam GS (2006) Cardiac isoform of alpha-2 macroglobulin - a new biomarker for myocardial infarcted diabetic patients. Atherosclerosis 186:173-176
8. Prabhakar R, Rajamanickam C (1993) Serum protein of 135 kDa molecular weight - a molecular signal for cardiac hypertrophy. Arch Biochem Biophys 302:425-430 (Pubitemid 23212693)
9. Ohkawa H, Ohishi N, Yagi K (1959) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358
10. Kakkar P, Das B, Viswanathan PN (1984) A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem Biophys 2:130-132 (Pubitemid 15207169)
11. Maehly AC, Chance B (1954) The assay of catalases and peroxidases. Methods Biochem Anal 1:357-424
12. Lawrence RA, Burk RF (1976) Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 4:952-958
13. David M, Richard JS (1983) Glutathione reductase. In: Bergmeyer HU Jr (ed) Methods of enzymatic analysis, vol 3. Academic Press, New York, p 258
14. Bergmeyer HU, Gawehn K, Grassl M (1974) Methods of enzymatic analysis, 2nd edn. Academic Press, New York, pp 521-522
15. Ellen SL, Reginald HG (1978) Regulation, Purification, and properties of xanthine dehydrogenase in Neurospora crassa. J Biol Chem 253:2604-2614
16. Cai L, Kang YJ (2001) Oxidative stress and cardiomyopathy: a brief review. Cardiovasc Toxicol 1:181-193 (Pubitemid 37013746)
17. Cai L, Li W, Wang G, Guo L, Jiang Y, Kang YJ (2002) Hyperglycemia- induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway. Diabetes 51:1938-1948 (Pubitemid 34564309)
18. Depre C, Young ME, Ying J, Singh Ahuja H, Han Q, Garza N, Davies PJA, Taegtmeyer H (2000) Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction. J Mol Cell Cardiol 32:985-996 (Pubitemid 30663106)
19. Berry CE, Hare JM (2004) Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications. J Physiol 555:589-606 (Pubitemid 38404582)
20. Wang J, Han Y, Su H, Mu L (2004) Expression of unique and developmental myosin heavy chain isoforms in adult human digastric muscle. J Histochem Cytochem 52:851-859 (Pubitemid 38857150)
21. Reiser PJ, Portman MA, Ning X-H, Moravec CS (2001) Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles. Am J Physiol Heart Circ Physiol 280:H1814-H1820
22. Corbett JM, Why HJ, Wheeler CH, Richardson PJ, Archard LC, Yacoub MH, Dunn MJ (1998) Cardiac protein abnormalities in dilated cardiomyopathy detected by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 19:2031-2042 (Pubitemid 28392250)
23. Ghatpande S, Shafiq S, Siddiqui MAQ (2001) Ventricular myosin light chain-2 gene expression in developing heart of chicken embryos. Biol Res 34:243