-
1
-
-
0344111641
-
Thalidomide and congenital abnormalities
-
Speirs AL. Thalidomide and congenital abnormalities. Lancet 1962;20(7224):303-5
-
(1962)
Lancet
, vol.20
, Issue.7224
, pp. 303-305
-
-
Speirs, A.L.1
-
2
-
-
85046242789
-
Drugs and congenital abnormalities
-
Hagen EO. Drugs and congenital abnormalities. Lancet 1963;1(7279):501
-
(1963)
Lancet
, vol.1
, Issue.7279
, pp. 501
-
-
Hagen, E.O.1
-
3
-
-
84883833410
-
Thalidomide in the treatment of lepra reactions
-
Sheskin J. Thalidomide in the treatment of lepra reactions. Clin Pharmacol Ther 1965;6:303-6
-
(1965)
Clin Pharmacol Ther
, vol.6
, pp. 303-306
-
-
Sheskin, J.1
-
4
-
-
0032100486
-
Thalidomide costimulates primary human t lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset
-
DOI 10.1084/jem.187.11.1885
-
Haslett PA, Corral LG, Albert M, Kaplan G. Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset. J Exp Med 1998;187(11):1885-92 (Pubitemid 28262451)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.11
, pp. 1885-1892
-
-
Haslett, P.A.J.1
Corral, L.G.2
Albert, M.3
Kaplan, G.4
-
5
-
-
0026080801
-
Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes
-
Sampaio EP, Sarno EN, Galilly R, et al. Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med 1991;173(3):699-703
-
(1991)
J Exp Med
, vol.173
, Issue.3
, pp. 699-703
-
-
Sampaio, E.P.1
Sarno, E.N.2
Galilly, R.3
-
6
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
D'Amato RJ, Loughnan MS, Flynn E, Folkman J. Thalidomide is an inhibitor of angiogenesis. Proc Natl Acad Sci USA 1994;91(9):4082-5 (Pubitemid 24139577)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.9
, pp. 4082-4085
-
-
D'Amato, R.J.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
7
-
-
0000364822
-
Remarks on the pathology of mollities ossium with cases
-
Solly S. Remarks on the pathology of mollities ossium with cases. Med Chir Trans Lond 1844;27:435-61
-
(1844)
Med Chir Trans Lond
, vol.27
, pp. 435-461
-
-
Solly, S.1
-
8
-
-
0026585927
-
Combination chemotherapy versus melphalan and prednisolone in the treatment of multiple myeloma: An overview of published trials
-
Gregory WM, Richards MA, Malpas JS. Combination chemotherapy versus melphalan and prednisolone in the treatment of multiple myeloma: an overview of published trials. J Clin Oncol 1992;10(2):334-42
-
(1992)
J Clin Oncol
, vol.10
, Issue.2
, pp. 334-342
-
-
Gregory, W.M.1
Richards, M.A.2
Malpas, J.S.3
-
9
-
-
0344076348
-
Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma. an overview of 6,633 patients from 27 randomized trials
-
Myeloma Trialists' Collaborative Group
-
Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma. an overview of 6,633 patients from 27 randomized trials. Myeloma Trialists' Collaborative Group. J Clin Oncol 1998;16(12):3832-42
-
(1998)
J Clin Oncol
, vol.16
, Issue.12
, pp. 3832-3842
-
-
-
10
-
-
41949130070
-
Improved survival in multiple myeloma and the impact of novel therapies
-
Kumar SK, Rajkumar SV, Dispenzieri A, et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood 2008;111(5):2516-20
-
(2008)
Blood
, vol.111
, Issue.5
, pp. 2516-2520
-
-
Kumar, S.K.1
Rajkumar, S.V.2
Dispenzieri, A.3
-
11
-
-
34249945940
-
Patterns of survival in multiple myeloma: A population-based study of patients diagnosed in Sweden from 1973 to 2003
-
Kristinsson SY, Landgren O, Dickman PW, et al. Patterns of survival in multiple myeloma: a population-based study of patients diagnosed in Sweden from 1973 to 2003. J Clin Oncol 2007;25(15):1993-9
-
(2007)
J Clin Oncol
, vol.25
, Issue.15
, pp. 1993-1999
-
-
Kristinsson, S.Y.1
Landgren, O.2
Dickman, P.W.3
-
12
-
-
41949114641
-
Recent major improvement in long-term survival of younger patients with multiple myeloma
-
Brenner H, Gondos A, Pulte D. Recent major improvement in long-term survival of younger patients with multiple myeloma. Blood 2008;111(5):2521-6
-
(2008)
Blood
, vol.111
, Issue.5
, pp. 2521-2526
-
-
Brenner, H.1
Gondos, A.2
Pulte, D.3
-
13
-
-
0024325842
-
Etoposide, dexamethasone, cytarabine, and cisplatin in vincristine, doxorubicin, and dexamethasone-refractory myeloma
-
Barlogie B, Velasquez WS, Alexanian R, Cabanillas F. Etoposide, dexamethasone, cytarabine, and cisplatin in vincristine, doxorubicin, and dexamethasone-refractory myeloma. J Clin Oncol 1989;7(10):1514-17 (Pubitemid 19245123)
-
(1989)
Journal of Clinical Oncology
, vol.7
, Issue.10
, pp. 1514-1517
-
-
Barlogie, B.1
Velasquez, W.S.2
Alexanian, R.3
Cabanillas, F.4
-
14
-
-
0022992058
-
Therapy of primary resistant and relapsed multiple myeloma
-
Barlogie B, Alexanian R. Therapy of primary resistant and relapsed multiple myeloma. Onkologie 1986;9(4):210-4 (Pubitemid 17190445)
-
(1986)
Onkologie
, vol.9
, Issue.4
, pp. 210-214
-
-
Barlogie, B.1
Alexanian, R.2
-
15
-
-
0020637486
-
Prednisone pulse therapy for refractory myeloma
-
Alexanian R, Yap BS, Bodey GP. Prednisone pulse therapy for refractory myeloma. Blood 1983;62(3):572-7 (Pubitemid 13001687)
-
(1983)
Blood
, vol.62
, Issue.3
, pp. 572-577
-
-
Alexanian, R.1
Yap, B.S.2
Bodey, G.P.3
-
16
-
-
0037739753
-
High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
-
DOI 10.1056/NEJMoa022340
-
Child JA, Morgan GJ, Davies FE, et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003;348(19):1875-83 (Pubitemid 36532313)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.19
, pp. 1875-1883
-
-
Child, J.A.1
Morgan, G.J.2
Davies, F.E.3
Owen, R.G.4
Bell, S.E.5
Hawkins, K.6
Brown, J.7
Drayson, M.T.8
Selby, P.J.9
-
17
-
-
8944220233
-
A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
-
DOI 10.1056/NEJM199607113350204
-
Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996;335(2):91-7 (Pubitemid 26240110)
-
(1996)
New England Journal of Medicine
, vol.335
, Issue.2
, pp. 91-97
-
-
Attal, M.1
Harousseau, J.-L.2
Stoppa, A.-M.3
Sotto, J.-J.4
Fuzibet, J.-G.5
Rossi, J.-F.6
Casassus, P.7
Maisonneuve, H.8
Facon, T.9
Ifrah, N.10
Payen, C.11
Bataille, R.12
-
18
-
-
0037973279
-
A phase 2 study of Bortezomib in relapsed, refractory myeloma
-
DOI 10.1056/NEJMoa030288
-
Richardson PG, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003;348(26):2609-17 (Pubitemid 36741588)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.26
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Alexanian, R.10
Siegel, D.11
Orlowski, R.Z.12
Kuter, D.13
Limentani, S.A.14
Lee, S.15
Hideshima, T.16
Esseltine, D.-L.17
Kauffman, M.18
Adams, J.19
Schenkein, D.P.20
Anderson, K.C.21
more..
-
19
-
-
33750607347
-
A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
-
Richardson PG, Blood E, Mitsiades CS, et al. A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Blood 2006;108(10):3458-64
-
(2006)
Blood
, vol.108
, Issue.10
, pp. 3458-3464
-
-
Richardson, P.G.1
Blood, E.2
Mitsiades, C.S.3
-
20
-
-
36349023319
-
Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma
-
DOI 10.1056/NEJMoa070594
-
Dimopoulos M, Spencer A, Attal M, et al. Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma. N Engl J Med 2007;357(21):2123-32 (Pubitemid 350146107)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.21
, pp. 2123-2132
-
-
Dimopoulos, M.1
Spencer, A.2
Attal, M.3
Prince, H.M.4
Harousseau, J.-L.5
Dmoszynska, A.6
San, M.J.7
Hellmann, A.8
Facon, T.9
Foa, R.10
Corso, A.11
Masliak, Z.12
Olesnyckyj, M.13
Yu, Z.14
Patin, J.15
Zeldis, J.B.16
Knight, R.D.17
-
21
-
-
36349010285
-
Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America
-
DOI 10.1056/NEJMoa070596
-
Weber DM, Chen C, Niesvizky R, et al. Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America. N Engl J Med 2007;357(21):2133-42 (Pubitemid 350146108)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.21
, pp. 2133-2142
-
-
Weber, D.M.1
Chen, C.2
Niesvizky, R.3
Wang, M.4
Belch, A.5
Stadtmauer, E.A.6
Siegel, D.7
Borrello, I.8
Rajkumar, S.V.9
Chanan-Khan, A.A.10
Lonial, S.11
Yu, Z.12
Patin, J.13
Olesnyckyj, M.14
Zeldis, J.B.15
Knight, R.D.16
-
22
-
-
34548539381
-
Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: Combination therapy improves time to progression
-
DOI 10.1200/JCO.2006.10.5460
-
Orlowski RZ, Nagler A, Sonneveld P, et al. Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression. J Clin Oncol 2007;25(25):3892-901 (Pubitemid 47477266)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.25
, pp. 3892-3901
-
-
Orlowski, R.Z.1
Nagler, A.2
Sonneveld, P.3
Blade, J.4
Hajek, R.5
Spencer, A.6
San, M.J.7
Robak, T.8
Dmoszynska, A.9
Horvath, N.10
Spicka, I.11
Sutherland, H.J.12
Suvorov, A.N.13
Zhuang, S.H.14
Parekh, T.15
Xiu, L.16
Yuan, Z.17
Rackoff, W.18
Harousseau, J.-L.19
-
23
-
-
76249096571
-
How I treat multiple myeloma in younger patients
-
Stewart AK, Richardson PG, San-Miguel JF. How I treat multiple myeloma in younger patients. Blood 2009;114(27):5436-43
-
(2009)
Blood
, vol.114
, Issue.27
, pp. 5436-5443
-
-
Stewart, A.K.1
Richardson, P.G.2
San-Miguel, J.F.3
-
24
-
-
79953647312
-
PX-171-004, An Ongoing Open-Label, Phase II Study of Single-Agent Carfilzomib (CFZ) in Patients with Relapsed or Refractory Myeloma (MM); Updated Results from the Bortezomib-Treated Cohort
-
The Multiple Myeloma Research Consortium (MMRC)
-
David Siegel LW, Orlowski RZ, Jonathan L, et al.; The Multiple Myeloma Research Consortium (MMRC). PX-171-004, An Ongoing Open-Label, Phase II Study of Single-Agent Carfilzomib (CFZ) in Patients with Relapsed or Refractory Myeloma (MM); Updated Results From the Bortezomib-Treated Cohort. ASH: Blood ASH Annual Meeting Abstracts; 2009
-
ASH: Blood ASH Annual Meeting Abstracts; 2009
-
-
David Siegel, L.W.1
Orlowski, R.Z.2
Jonathan, L.3
-
25
-
-
79953654564
-
Updated Results of Bortezomib-Naïve Patients in PX-171-004, An Ongoing Open-Label, Phase II Study of Single-Agent Carfilzomib (CFZ) in Patients with Relapsed or Refractory Myeloma (MM)
-
The Multiple Myeloma Research Consortium (MMRC)
-
Luhua Wang DS, Jonathan L, Kaufman A, et al.; The Multiple Myeloma Research Consortium (MMRC). Updated Results of Bortezomib-Naïve Patients in PX-171-004, An Ongoing Open-Label, Phase II Study of Single-Agent Carfilzomib (CFZ) in Patients with Relapsed or Refractory Myeloma (MM). ASH: Blood ASH Annual Meeting Abstracts; 2009
-
ASH: Blood ASH Annual Meeting Abstracts; 2009
-
-
Luhua Wang, D.S.1
Jonathan, L.2
Kaufman, A.3
-
26
-
-
79953656385
-
Phase Ib Multicenter Dose Escalation Study of Carfilzomib Plus Lenalidomide and Low Dose Dexamethasone (CRd) in Relapsed and Refractory Multiple Myeloma (MM)
-
The Multiple Myeloma Research Consortium (MMRC)
-
Ruben Niesvizky LW, Orlowski RZ, Bensinger W, et al.; The Multiple Myeloma Research Consortium (MMRC). Phase Ib Multicenter Dose Escalation Study of Carfilzomib Plus Lenalidomide and Low Dose Dexamethasone (CRd) in Relapsed and Refractory Multiple Myeloma (MM). ASH: Blood ASH Annual Meeting Abstracts; 2009
-
ASH: Blood ASH Annual Meeting Abstracts; 2009
-
-
Ruben Niesvizky, L.W.1
Orlowski, R.Z.2
Bensinger, W.3
-
27
-
-
64749113465
-
Treatment of relapsed/refractory multiple myeloma
-
Kastritis E, Palumbo A, Dimopoulos MA. Treatment of relapsed/refractory multiple myeloma. Semin Hematol 2009;46(2):143-57
-
(2009)
Semin Hematol
, vol.46
, Issue.2
, pp. 143-157
-
-
Kastritis, E.1
Palumbo, A.2
Dimopoulos, M.A.3
-
28
-
-
0033764086
-
High-dose therapy autotransplantation/intensification vs continued standard chemotherapy in multiple myeloma in first remission. Results of a non-randomized study from a single institution
-
Blade J, Esteve J, Rives S, et al. High-dose therapy autotransplantation/ intensification vs continued standard chemotherapy in multiple myeloma in first remission. Results of a non-randomized study from a single institution. Bone Marrow Transplant 2000;26(8):845-9
-
(2000)
Bone Marrow Transplant
, vol.26
, Issue.8
, pp. 845-849
-
-
Blade, J.1
Esteve, J.2
Rives, S.3
-
29
-
-
1942534043
-
The evolution of thalidomide and its IMiD derivatives as anticancer agents
-
Bartlett JB, Dredge K, Dalgleish AG. The evolution of thalidomide and its IMiD derivatives as anticancer agents. Nat Rev Cancer 2004;4(4):314-22 (Pubitemid 38525287)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.4
, pp. 314-322
-
-
Bartlett, J.B.1
Dredge, K.2
Dalgleish, A.G.3
-
30
-
-
77949537596
-
Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma
-
Racanelli V, Leone P, Frassanito MA, et al. Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma. Blood 2010;115(6):1185-93
-
(2010)
Blood
, vol.115
, Issue.6
, pp. 1185-1193
-
-
Racanelli, V.1
Leone, P.2
Frassanito, M.A.3
-
31
-
-
54049129702
-
Differential pattern of CD4+ and CD8+ T-cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma
-
Goodyear OC, Pratt G, McLarnon A, et al. Differential pattern of CD4+ and CD8+ T-cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma. Blood 2008;112(8):3362-72
-
(2008)
Blood
, vol.112
, Issue.8
, pp. 3362-3372
-
-
Goodyear, O.C.1
Pratt, G.2
McLarnon, A.3
-
32
-
-
58849093606
-
CD4(+)CD25(+)FoxP3 (+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-) alphabetaTCR(+) Double Negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden
-
Feyler S, von Lilienfeld-Toal M, Jarmin S, et al. CD4(+)CD25(+)FoxP3 (+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-) alphabetaTCR(+) Double Negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden. Br J Haematol 2009;144(5):686-95
-
(2009)
Br J Haematol
, vol.144
, Issue.5
, pp. 686-695
-
-
Feyler, S.1
Von Lilienfeld-Toal, M.2
Jarmin, S.3
-
33
-
-
39549084084
-
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma
-
DOI 10.1073/pnas.0711293105
-
Jinushi M, Vanneman M, Munshi NC, et al. MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma. Proc Natl Acad Sci USA 2008;105(4):1285-90 (Pubitemid 351397045)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.4
, pp. 1285-1290
-
-
Jinushi, M.1
Vanneman, M.2
Munshi, N.C.3
Tai, Y.-T.4
Prabhala, R.H.5
Ritz, J.6
Neuberg, D.7
Anderson, K.C.8
Carrasco, D.R.9
Dranoff, G.10
-
34
-
-
0034663033
-
B7-2-positive myeloma: Incidence, clinical characteristics, prognostic significance, and implications for tumor immunotherapy
-
Pope B, Brown RD, Gibson J, et al. B7-2-positive myeloma: incidence, clinical characteristics, prognostic significance, and implications for tumor immunotherapy. Blood 2000;96(4):1274-9 (Pubitemid 30658455)
-
(2000)
Blood
, vol.96
, Issue.4
, pp. 1274-1279
-
-
Pope, B.1
Brown, R.D.2
Gibson, J.3
Yuen, E.4
Joshua, D.5
-
35
-
-
0037093854
-
Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity
-
Dredge K, Marriott JB, Todryk SM, et al. Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity. J Immunol 2002;168(10):4914-19 (Pubitemid 34495953)
-
(2002)
Journal of Immunology
, vol.168
, Issue.10
, pp. 4914-4919
-
-
Dredge, K.1
Marriott, J.B.2
Todryk, S.M.3
Muller, G.W.4
Chen, R.5
Stirling, D.I.6
Dalgleish, A.G.7
-
36
-
-
52549088421
-
Immunomodulatory drugs Revlimid (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation
-
Zhu D, Corral LG, Fleming YW, Stein B. Immunomodulatory drugs Revlimid (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation. Cancer Immunol Immunother 2008;57(12):1849-59
-
(2008)
Cancer Immunol Immunother
, vol.57
, Issue.12
, pp. 1849-1859
-
-
Zhu, D.1
Corral, L.G.2
Fleming, Y.W.3
Stein, B.4
-
37
-
-
0035412366
-
Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
-
Davies FE, Raje N, Hideshima T, et al. Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma. Blood 2001;98(1):210-16
-
(2001)
Blood
, vol.98
, Issue.1
, pp. 210-216
-
-
Davies, F.E.1
Raje, N.2
Hideshima, T.3
-
38
-
-
67349107194
-
The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
-
Galustian C, Meyer B, Labarthe MC, et al. The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells. Cancer Immunol Immunother 2009;58(7):1033-45
-
(2009)
Cancer Immunol Immunother
, vol.58
, Issue.7
, pp. 1033-1045
-
-
Galustian, C.1
Meyer, B.2
Labarthe, M.C.3
-
39
-
-
0035992360
-
Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis
-
Rajkumar SV, Mesa RA, Fonseca R, et al. Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis. Clin Cancer Res 2002;8(7):2210-16 (Pubitemid 34753592)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.7
, pp. 2210-2216
-
-
Rajkumar, S.V.1
Mesa, R.A.2
Fonseca, R.3
Schroeder, G.4
Plevak, M.F.5
Dispenzieri, A.6
Lacy, M.Q.7
Lust, J.A.8
Witzig, T.E.9
Gertz, M.A.10
Kyle, R.A.11
Russell, S.J.12
Greipp, P.R.13
-
40
-
-
0038284068
-
A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma
-
Vacca A, Ria R, Ribatti D, et al. A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma. Haematologica 2003;88(2):176-85 (Pubitemid 37101495)
-
(2003)
Haematologica
, vol.88
, Issue.2
, pp. 176-185
-
-
Vacca, A.1
Ria, R.2
Ribatti, D.3
Semeraro, F.4
Djonov, V.5
Di, R.F.6
Dammacco, F.7
-
41
-
-
1542608411
-
Effect of thalidomide therapy on bone marrow angiogenesis in multiple myeloma
-
DOI 10.1038/sj.leu.2403285
-
Kumar S, Witzig TE, Dispenzieri A, et al. Effect of thalidomide therapy on bone marrow angiogenesis in multiple myeloma. Leukemia 2004;18(3):624-7 (Pubitemid 38425879)
-
(2004)
Leukemia
, vol.18
, Issue.3
, pp. 624-627
-
-
Kumar, S.1
Witzig, T.E.2
Dispenzieri, A.3
Lacy, M.Q.4
Wellik, L.E.5
Fonseca, R.6
Lust, J.A.7
Gertz, M.A.8
Kyle, R.A.9
Greipp, P.R.10
Rajkumar, S.V.11
-
42
-
-
36849024949
-
Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo
-
DOI 10.1111/j.1365-2141.2007.06841.x
-
Reddy N, Hernandez-Ilizaliturri FJ, Deeb G, et al. Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo. Br J Haematol 2008;140(1):36-45 (Pubitemid 350233246)
-
(2008)
British Journal of Haematology
, vol.140
, Issue.1
, pp. 36-45
-
-
Reddy, N.1
Hernandez-Ilizaliturri, F.J.2
Deeb, G.3
Roth, M.4
Vaughn, M.5
Knight, J.6
Wallace, P.7
Czuczman, M.S.8
-
43
-
-
60449115552
-
The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
-
Lu L, Payvandi F, Wu L, et al. The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions. Microvasc Res 2009;77(2):78-86
-
(2009)
Microvasc Res
, vol.77
, Issue.2
, pp. 78-86
-
-
Lu, L.1
Payvandi, F.2
Wu, L.3
-
44
-
-
70349739288
-
Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and multiple myeloma through a LSD1-mediated epigenetic mechanism
-
Escoubet-Lozach L, Lin IL, Jensen-Pergakes K, et al. Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and multiple myeloma through a LSD1-mediated epigenetic mechanism. Cancer Res 2009;69(18):7347-56
-
(2009)
Cancer Res
, vol.69
, Issue.18
, pp. 7347-7356
-
-
Escoubet-Lozach, L.1
Lin, I.L.2
Jensen-Pergakes, K.3
-
45
-
-
0037097595
-
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: Therapeutic implications
-
DOI 10.1182/blood.V99.12.4525
-
Mitsiades N, Mitsiades CS, Poulaki V, et al. Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications. Blood 2002;99(12):4525-30 (Pubitemid 34627223)
-
(2002)
Blood
, vol.99
, Issue.12
, pp. 4525-4530
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.C.7
Treon, S.P.8
Anderson, K.C.9
-
46
-
-
51649094129
-
Dexamethasone-induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors
-
Sharma S, Lichtenstein A. Dexamethasone-induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors. Blood 2008;112(4):1338-45
-
(2008)
Blood
, vol.112
, Issue.4
, pp. 1338-1345
-
-
Sharma, S.1
Lichtenstein, A.2
-
47
-
-
0034331194
-
Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
-
Hideshima T, Chauhan D, Shima Y, et al. Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy. Blood 2000;96(9):2943-50
-
(2000)
Blood
, vol.96
, Issue.9
, pp. 2943-2950
-
-
Hideshima, T.1
Chauhan, D.2
Shima, Y.3
-
48
-
-
62549117773
-
Pathogenesis of myeloma bone disease
-
Roodman GD. Pathogenesis of myeloma bone disease. Leukemia 2009;23(3):435-41
-
(2009)
Leukemia
, vol.23
, Issue.3
, pp. 435-441
-
-
Roodman, G.D.1
-
49
-
-
14344250737
-
Fracture risk with multiple myeloma: A population-based study
-
DOI 10.1359/JBMR.041131
-
Melton LJ III, Kyle RA, Achenbach SJ, et al. Fracture risk with multiple myeloma: a population-based study. J Bone Miner Res 2005;20(3):487-93 (Pubitemid 40293498)
-
(2005)
Journal of Bone and Mineral Research
, vol.20
, Issue.3
, pp. 487-493
-
-
Melton III, L.J.1
Kyle, R.A.2
Achenbach, S.J.3
Oberg, A.L.4
Rajkumar, S.V.5
-
50
-
-
33645736007
-
Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU.1
-
Anderson G, Gries M, Kurihara N, et al. Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU.1. Blood 2006;107(8):3098-105
-
(2006)
Blood
, vol.107
, Issue.8
, pp. 3098-3105
-
-
Anderson, G.1
Gries, M.2
Kurihara, N.3
-
51
-
-
67651111993
-
Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases
-
Xu Y, Li J, Ferguson GD, et al. Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases. Blood 2009;114(2):338-45
-
(2009)
Blood
, vol.114
, Issue.2
, pp. 338-345
-
-
Xu, Y.1
Li, J.2
Ferguson, G.D.3
-
52
-
-
0029742896
-
Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity
-
Corral LG, Muller GW, Moreira AL, et al. Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity. Mol Med 1996;2(4):506-15 (Pubitemid 26271704)
-
(1996)
Molecular Medicine
, vol.2
, Issue.4
, pp. 506-515
-
-
Corral, L.G.1
Muller, G.W.2
Moreira, A.L.3
Chen, Y.4
Wu, M.5
Stirling, D.6
Kaplan, G.7
-
53
-
-
20444422917
-
Cyclooxygenase-2 (COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome
-
DOI 10.1182/blood-2004-11-4201
-
Ladetto M, Vallet S, Trojan A, et al. Cyclooxygenase-2 (COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome. Blood 2005;105(12):4784-91 (Pubitemid 40807304)
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4784-4791
-
-
Ladetto, M.1
Vallet, S.2
Trojan, A.3
Dell'Aquila, M.4
Monitillo, L.5
Rosato, R.6
Santo, L.7
Drandi, D.8
Bertola, A.9
Falco, P.10
Cavallo, F.11
Ricca, I.12
De Marco, F.13
Mantoan, B.14
Bode-Lesniewska, B.15
Pagliano, G.16
Francese, R.17
Rocci, A.18
Astolfi, M.19
Compagno, M.20
Mariani, S.21
Godio, L.22
Marino, L.23
Ruggeri, M.24
Omede, P.25
Palumbo, A.26
Boccadoro, M.27
more..
-
54
-
-
23044449530
-
A multicenter phase II trial of thalidomide and celecoxib for patients with relapsed and refractory multiple myeloma
-
DOI 10.1158/1078-0432.CCR-05-0213
-
Prince HM, Mileshkin L, Roberts A, et al. A multicenter phase II trial of thalidomide and celecoxib for patients with relapsed and refractory multiple myeloma. Clin Cancer Res 2005;11(15):5504-14 (Pubitemid 41060827)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.15
, pp. 5504-5514
-
-
Prince, H.M.1
Mileshkin, L.2
Roberts, A.3
Ganju, V.4
Underbill, C.5
Catalane, J.6
Bell, R.7
Seymour, J.F.8
Westerman, D.9
Simmons, P.J.10
Lillie, K.11
Milner, A.D.12
Di, I.J.13
Zeldis, J.B.14
Ramsay, R.15
-
55
-
-
33847345109
-
Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2
-
DOI 10.1007/s10875-007-9070-6
-
Ferguson GD, Jensen-Pergakes K, Wilkey C, et al. Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2. J Clin Immunol 2007;27(2):210-20 (Pubitemid 46348725)
-
(2007)
Journal of Clinical Immunology
, vol.27
, Issue.2
, pp. 210-220
-
-
Ferguson, G.D.1
Jensen-Pergakes, K.2
Wilkey, C.3
Jhaveri, U.4
Richard, N.5
Verhelle, D.6
De Parseval, L.M.7
Corral, L.G.8
Xie, W.9
Morris, C.L.10
Brady, H.11
Chan, K.12
-
56
-
-
4344693453
-
Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma
-
DOI 10.1200/JCO.2004.10.052
-
Schey SA, Fields P, Bartlett JB, et al. Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma. J Clin Oncol 2004;22(16):3269-76 (Pubitemid 41103682)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.16
, pp. 3269-3276
-
-
Schey, S.A.1
Fields, P.2
Bartlett, J.B.3
Clarke, I.A.4
Ashan, G.5
Knight, R.D.6
Streetly, M.7
Dalgleish, A.G.8
-
57
-
-
40449135275
-
Alternate day pomalidomide retains anti-myeloma effect with reduced adverse events and evidence of in vivo immunomodulation
-
DOI 10.1111/j.1365-2141.2008.07013.x
-
Streetly MJ, Gyertson K, Daniel Y, et al. Alternate day pomalidomide retains anti-myeloma effect with reduced adverse events and evidence of in vivo immunomodulation. Br J Haematol 2008;141(1):41-51 (Pubitemid 351350609)
-
(2008)
British Journal of Haematology
, vol.141
, Issue.1
, pp. 41-51
-
-
Streetly, M.J.1
Gyertson, K.2
Daniel, Y.3
Zeldis, J.B.4
Kazmi, M.5
Schey, S.A.6
-
58
-
-
79953671569
-
A Phase 1/2 Multi-Center, Randomized, Open Label Dose Escalation Study to Determine the Maximum Tolerated Dose, Safety, and Efficacy of Pomalidomide Alone or in Combination with Low-Dose Dexamethasone in Patients with Relapsed and Refractory Multiple Myeloma Who Have Received Prior Treatment That Includes Lenalidomide and Bortezomib
-
abstract no: 301
-
Paul Richardson DS, Baz R, Kelley SL, et al. A Phase 1/2 Multi-Center, Randomized, Open Label Dose Escalation Study to Determine the Maximum Tolerated Dose, Safety, and Efficacy of Pomalidomide Alone or in Combination with Low-Dose Dexamethasone in Patients with Relapsed and Refractory Multiple Myeloma Who Have Received Prior Treatment That Includes Lenalidomide and Bortezomib [abstract no: 301]. ASH: Blood ASH meeting Abstracts; 2009
-
ASH: Blood ASH Meeting Abstracts; 2009
-
-
Paul Richardson, D.S.1
Baz, R.2
Kelley, S.L.3
-
59
-
-
73849086725
-
Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma
-
Lacy MQ, Hayman SR, Gertz MA, et al. Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma. J Clin Oncol 2009;27(30):5008-14
-
(2009)
J Clin Oncol
, vol.27
, Issue.30
, pp. 5008-5014
-
-
Lacy, M.Q.1
Hayman, S.R.2
Gertz, M.A.3
-
60
-
-
78149468560
-
Pomalidomide (CC4047) plus low dose dexamethasone (Pom/dex) is active and well tolerated in lenalidomide refractory multiple myeloma (MM)
-
Lacy MQ, Hayman SR, Gertz MA, et al. Pomalidomide (CC4047) plus low dose dexamethasone (Pom/dex) is active and well tolerated in lenalidomide refractory multiple myeloma (MM). Leukemia 2010;24(11):1934-9
-
(2010)
Leukemia
, vol.24
, Issue.11
, pp. 1934-1939
-
-
Lacy, M.Q.1
Hayman, S.R.2
Gertz, M.A.3
-
61
-
-
79953645684
-
Phase 2 Study of 2 Modalities of Pomalidomide (CC4047) Plus Low-Dose Dexamethasone as Therapy for Relapsed Multiple Myeloma. IFM 2009-02
-
Thierry Facon
-
Xavier Leleu MA, Moreau P, Duhamel A, et al.; Thierry Facon. Phase 2 Study of 2 Modalities of Pomalidomide (CC4047) Plus Low-Dose Dexamethasone as Therapy for Relapsed Multiple Myeloma. IFM 2009-02. Blood ASH Annual Meeting Abstracts; 2010
-
Blood ASH Annual Meeting Abstracts; 2010
-
-
Xavier Leleu, M.A.1
Moreau, P.2
Duhamel, A.3
-
62
-
-
79953653315
-
Pomalidomide Plus Low-Dose Dexamethasone in Myeloma Refractory to Both Bortezomib and Lenalidomide: Comparison of Two Dosing Strategies in Dual-Refractory Disease
-
Martha Lacy SM, Gertz MAA, Suzanne R, et al. Pomalidomide Plus Low-Dose Dexamethasone In Myeloma Refractory to Both Bortezomib and Lenalidomide: Comparison of Two Dosing Strategies In Dual-Refractory Disease. ASH: Blood ASH Annual Meeting Abstracts; 2010
-
ASH: Blood ASH Annual Meeting Abstracts; 2010
-
-
Martha Lacy, S.M.1
Gertz, M.A.A.2
Suzanne, R.3
-
63
-
-
77950607507
-
Stem cell transplantation in multiple myeloma: Impact of response failure with thalidomide or lenalidomide induction
-
quiz 560
-
Gertz MA, Kumar S, Lacy MQ, et al. Stem cell transplantation in multiple myeloma: impact of response failure with thalidomide or lenalidomide induction. Blood 2010;115(12):2348-53, quiz 560
-
(2010)
Blood
, vol.115
, Issue.12
, pp. 2348-2353
-
-
Gertz, M.A.1
Kumar, S.2
Lacy, M.Q.3
-
64
-
-
77954618168
-
Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
-
Richardson PG, Weller E, Lonial S, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood 2010;116(5):679-86
-
(2010)
Blood
, vol.116
, Issue.5
, pp. 679-686
-
-
Richardson, P.G.1
Weller, E.2
Lonial, S.3
-
65
-
-
77954660886
-
Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: Phase 1 results from the multicenter EVOLUTION study
-
Kumar SK, Flinn I, Noga SJ, et al. Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: phase 1 results from the multicenter EVOLUTION study. Leukemia 2010;24(7):1350-6
-
(2010)
Leukemia
, vol.24
, Issue.7
, pp. 1350-1356
-
-
Kumar, S.K.1
Flinn, I.2
Noga, S.J.3
-
66
-
-
79953672883
-
The anti-proliferative effect of lenalidomide on MM cells in vitro is ameliorated by prior exposure to pomalidomide, an agent with activity against lenalidomide resistant MM cells
-
Adams MSP, Bartlett JB. The anti-proliferative effect of lenalidomide on MM cells in vitro is ameliorated by prior exposure to pomalidomide, an agent with activity against lenalidomide resistant MM cells. ASH: Blood ASH Annual Meeting Abstracts; 2009
-
ASH: Blood ASH Annual Meeting Abstracts; 2009
-
-
Adams, M.S.P.1
Bartlett, J.B.2
-
67
-
-
64649083365
-
Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure
-
Spencer A, Prince HM, Roberts AW, et al. Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure. J Clin Oncol 2009;27(11):1788-93
-
(2009)
J Clin Oncol
, vol.27
, Issue.11
, pp. 1788-1793
-
-
Spencer, A.1
Prince, H.M.2
Roberts, A.W.3
-
68
-
-
33644833147
-
Thalidomide and hematopoietic-cell transplantation for multiple myeloma
-
DOI 10.1056/NEJMoa053583
-
Barlogie B, Tricot G, Anaissie E, et al. Thalidomide and hematopoietic-cell transplantation for multiple myeloma. N Engl J Med 2006;354(10):1021-30 (Pubitemid 43357806)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.10
, pp. 1021-1030
-
-
Barlogie, B.1
Tricot, G.2
Anaissie, E.3
Shaughnessy, J.4
Rasmussen, E.5
Van Rhee, F.6
Fassas, A.7
Zangari, M.8
Hollmig, K.9
Pineda-Roman, M.10
Lee, C.11
Talamo, G.12
Thertulien, R.13
Kiwan, E.14
Krishna, S.15
Fox, M.16
Crowley, J.17
-
69
-
-
33751164196
-
Maintenance therapy with thalidomide improves survival in patients with multiple myeloma
-
Attal M, Harousseau JL, Leyvraz S, et al. Maintenance therapy with thalidomide improves survival in patients with multiple myeloma. Blood 2006;108(10):3289-94
-
(2006)
Blood
, vol.108
, Issue.10
, pp. 3289-3294
-
-
Attal, M.1
Harousseau, J.L.2
Leyvraz, S.3
-
70
-
-
77649215631
-
Bortezomib as induction before autologous transplantation, followed by lenalidomide as consolidation-maintenance in untreated multiple myeloma patients
-
Palumbo A, Gay F, Falco P, et al. Bortezomib as induction before autologous transplantation, followed by lenalidomide as consolidation- maintenance in untreated multiple myeloma patients. J Clin Oncol 2010;28(5):800-7
-
(2010)
J Clin Oncol
, vol.28
, Issue.5
, pp. 800-807
-
-
Palumbo, A.1
Gay, F.2
Falco, P.3
-
71
-
-
79953651451
-
-
San-Miguel ASH
-
Maria-Victoria Mateos LL-C, Hernandez MT, de la Rubia J, et al. San-Miguel. Multicenter, Randomized, Open-Label, Phase III Trial of Lenalidomide-Dexamethasone (Len/dex) Vs Therapeutic Abstention in Smoldering Multiple Myeloma at High Risk of Progression to SymptomaticMM: results of the first interim analysis. ASH; 2009
-
(2009)
Multicenter, Randomized, Open-Label, Phase III Trial of Lenalidomide-Dexamethasone (Len/dex) Vs Therapeutic Abstention in Smoldering Multiple Myeloma at High Risk of Progression to SymptomaticMM: Results of the First Interim Analysis
-
-
Maria-Victoria Mateos, L.L.-C.1
Hernandez, M.T.2
De La Rubia, J.3
-
72
-
-
78751699860
-
Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination based on hTERT and survivin following ASCT for myeloma
-
Rapoport AP, Aqui NA, Stadtmauer EA, et al. Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination based on hTERT and survivin following ASCT for myeloma. Blood 2011;117(3):788-97
-
(2011)
Blood
, vol.117
, Issue.3
, pp. 788-797
-
-
Rapoport, A.P.1
Aqui, N.A.2
Stadtmauer, E.A.3
-
73
-
-
78650969510
-
Transfer of influenza vaccine-primed co-stimulated autologous T cells after stem cell transplantation for multiple myeloma leads to reconstitution of influenza immunity: Results of a randomized clinical trial
-
Stadtmauer EA, Vogl DT, Luning Prak E, et al. Transfer of influenza vaccine-primed co-stimulated autologous T cells after stem cell transplantation for multiple myeloma leads to reconstitution of influenza immunity: results of a randomized clinical trial. Blood 2011;117:63-71
-
(2011)
Blood
, vol.117
, pp. 63-71
-
-
Stadtmauer, E.A.1
Vogl, D.T.2
Luning Prak, E.3
-
74
-
-
38149059827
-
Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells
-
Moutouh-de Parseval LA, Verhelle D, Glezer E, et al. Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells. J Clin Invest 2008;118(1):248-58
-
(2008)
J Clin Invest
, vol.118
, Issue.1
, pp. 248-258
-
-
Moutouh-de Parseval, L.A.1
Verhelle, D.2
Glezer, E.3
|