Long-term randomized controlled trial of a novel nanopowder hemostatic agent (TC-325) for control of severe arterial upper gastrointestinal bleeding in a porcine model

Endoscopy

Volumn 43, Issue 4, 2011, Pages 296-299

  Giday, S A ^a,b   Kim, Y ^a,c   Krishnamurty, D M ^a   Ducharme, R ^d   Liang, D B ^a   Shin, E J ^a   Dray, X ^a,e   Hutcheon, D ^a   Moskowitz, K ^d   Donatelli, G ^a   Rueben, D ^a   Canto, M I ^a   Okolo, P I ^a   Kalloo, A N ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c Korea University College of Medicine   (South Korea)

^d Cook Endoscopy ^*  (United States)

^e HÔPITAL LARIBOISIÈRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFAZOLIN; HEMOSTATIC AGENT; HEPARIN; HISTAMINE H2 RECEPTOR ANTAGONIST; RANITIDINE; TC 325; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL EMBOLISM; AUTOPSY; BLOOD CLOTTING TIME; CATHETER; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; FOREIGN BODY; GASTROINTESTINAL HEMORRHAGE; GASTROSTOMY; GRANULOMA; LACERATION; LAPAROTOMY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SWINE;

ANIMALS; FEMALE; GASTROEPIPLOIC ARTERY; GASTROINTESTINAL HEMORRHAGE; HEMOSTATICS; NANOPARTICLES; POWDERS; SUS SCROFA;

EID: 79953651939     PISSN: 0013726X     EISSN: 14388812     Source Type: Journal    
DOI: 10.1055/s-0030-1256125     Document Type: Article

References (18)

1. Palmer K. Acute upper gastrointestinal hemorrhage. Br Med Bull 2007 83 307-324
2. Fallah M A., Prakash C, Edmundowicz S. Acute gastrointestinal bleeding. Med Clin North Am 2000 84 1183-1208
3. Gupta P K., Fleischer D E. Nonvariceal upper gastrointestinal bleeding. Med Clin North Am 1993 77 973-992 (Pubitemid 23281620)
4. Yavorski R T., Wong R K., Maydonovitch C et al. Analysis of 3,294 cases of upper gastrointestinal bleeding in military medical facilities. Am J Gastroenterol 1995 90 568-573
5. Alam H B., Burris D, DaCorta J A., Rhee P. Hemorrhage control in the battlefield: role of new hemostatic agents. Mil Med 2005 170 63-69 (Pubitemid 40731920)
6. Carraway J W., Kent D, Young K et al. Comparison of a new mineral based hemostatic agent to a commercially available granular zeolite agent for hemostasis in a swine model of lethal extremity arterial hemorrhage. Resuscitation 2008 78 230-235. Epub 2008 May 15
7. Kheirabadi B S., Edens J W., Terrazas I B. et al. Comparison of new hemostatic granules/powders with currently deployed hemostatic products in a lethal model of extremity arterial hemorrhage in swine. J Trauma 2009 66 316-326; discussion 327 - 328
8. Ward K R., Tiba M H., Holbert W H. et al. Comparison of a new hemostatic agent to current combat hemostatic agents in a swine model of lethal extremity arterial hemorrhage. J Trauma 2007 63 276-283; discussion 283 - 284 (Pubitemid 47254631)
9. Institute for Laboratory Animal Research, Commission on Life Sciences, National Research Council. Guide for the care and use of laboratory animals. 1966
10. Pfau P R., Cooper G S., Carlson M D. et al. Success and shortcomings of a clinical care pathway in the management of acute nonvariceal upper gastrointestinal bleeding. Am J Gastroenterol 2004 99 425-431 (Pubitemid 38524118)
11. Forrest J A., Finlayson N D., Shearman D J. Endoscopy in gastrointestinal bleeding. Lancet 1974 17 394-397
12. Chung S S., Lau J Y., Sung J J. et al. Randomised comparison between adrenaline injection alone and adrenaline injection plus heat probe treatment for actively bleeding ulcers. BMJ 1997 314 1307-1311 (Pubitemid 27183317)
13. Kumar P, Fleischer D E. Thermal therapy for gastrointestinal bleeding. Gastrointest Endosc Clin N Am 1997 7 593-609 (Pubitemid 27462390)
14. Havanond C, Havanond P. Argon plasma coagulation therapy for acute non-variceal upper gastrointestinal bleeding. Cochrane Database Syst Rev 2005 Apr 18; 2 CD003791
15. Gevers A M., De Goede E, Simoens M et al. A randomized trial comparing injection therapy with hemoclip and with injection combined with hemoclip for bleeding ulcers. Gastrointest Endosc 2002 55 466-469 (Pubitemid 41123494)
16. Laine L, McQuaid K R. Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol 2009 7 33-47; quiz 1 - 2. Epub 2008 Aug 16
17. Vergara M, Calvet X, Gisbert J P. Epinephrine injection versus epinephrine injection and a second endoscopic method in high risk bleeding ulcers. Cochrane Database Syst Rev 2007 Apr 18; 2 CD005584
18. Lin H J., Perng C L., Sun I C. et al. Endoscopic haemoclip versus heater probe thermocoagulation plus hypertonic saline-epinephrine injection for peptic ulcer bleeding. Dig Liver Dis 2003 35 898-902