Transcriptional regulation of bone sialoprotein gene by interleukin-11

Gene

Volumn 476, Issue 1-2, 2011, Pages 46-55

  Wang, Shuang ^a,b   Sasaki, Yoko ^a   Zhou, Liming ^a,c   Matsumura, Hiroyoshi ^a   Araki, Shouta ^a   Mezawa, Masaru ^a   Takai, Hideki ^a   Chen, Zhen ^b   Ogata, Yorimasa ^a  

^a NIHON UNIVERSITY   (Japan)

^b Stomatology Collage of Tianjn Medical University   (China)

^c Anhui Province Stomatology Hospital   (China)

Author keywords

Bone sialoprotein; IL 11; Osteoblasts; Transcription

Indexed keywords

BONE SIALOPROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FIBROBLAST GROWTH FACTOR 2; HOX PROTEIN; INTERLEUKIN 11; LUCIFERASE; MESSENGER RNA; PROTEIN C FOS; PROTEIN C JUN; PROTEIN TYROSINE KINASE INHIBITOR; SMAD1 PROTEIN; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR FRA 2; TRANSCRIPTION FACTOR JUND; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN TARGETING; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; CELL LINE; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA PRIMERS; INTEGRIN-BINDING SIALOPROTEIN; INTERLEUKIN-11; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OSTEOBLASTS; PROMOTER REGIONS, GENETIC; RATS; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

RATTUS;

EID: 79953331392     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2011.01.016     Document Type: Article

References (75)

1. Alberts A.S., Arias J., Hagiwara M., Montminy M.R., Feeramiso J.R. Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on ser-133 is transcriptionally active upon its introduction into fibroblast nuclei. J. Biol. Chem. 1994, 269:7623-7630.
2. Allan E.H., Hilton D.J., Brown M.A., Evely R.S., Yumita S., Metcalf D., Gough N.M., Ng K.W., Nicola N.A., Martin T.J. Osteoblasts display receptors for and responses to leukemia inhibitory factor. J. Cell. Physiol. 1990, 14:110-119.
3. Araki S., Mezawa M., Sasaki Y., Yang L., Li Z., Takai H., Nakayama Y., Ogata Y. Parathyroid hormone regulation of the human bone sialoprotein gene transcription is mediated through two cAMP response elements. J. Cell. Biochem. 2009, 106:618-625.
4. Bellahcène A., Merville M.P., Castronovo V. Expression of bone sialoprotein, a bone matrix protein, in human breast cancer. Cancer Res. 1994, 54:2823-2826.
5. Benson M.D., Aubin J.E., Xiao G., Thomas P.E., Franceschi R.T. Cloning of a 2.5kb murine bone sialoprotein promoter fragment and functional analysis of putative Osf2 binding sites. J. Bone Miner. Res. 1999, 14:396-405.
6. Benson M.D., Bargeon J.L., Xiao G., Thomas P.E., Kim A., Cui Y., Franceschi R.T. Identification of a homeodomain binding element in the bone sialoprotein gene promoter that is required for its osteoblast-selective expression. J. Biol. Chem. 2000, 275:13907-13917.
7. Bruno E., Briddell R.A., Cooper R.J., Hoffman R. Effects of recombinant interleukin 11 on human megakaryocyte progenitor cells. Exp. Hematol. 1991, 19:378-381.
8. Burstein S.A., Mei R.L., Henthorn J., Friese P., Turner K. Leukemia inhibitory factor and interleukin-11 promote maturation of murine and human megakaryocytes in vitro. J. Cell. Physiol. 1992, 153:305-312.
9. Chen J., Shapiro H.S., Wrana J.L., Reimer S., Heersche J.N.M., Sodek J. Localization of bone sialoprotein (BSP) expression to sites of mineralized tissue formation in fetal rat tissues by in situ hybridization. Matrix 1991, 11:133-143.
10. Chen J., Shapiro H.S., Sodek J. Developmental expression of bone sialoprotain mRNA in rat mineralized connective tissues. J. Bone Miner. Res. 1992, 7:987-997.
11. Chen B.P., Liang G., Whelan J., Hai T. ATF3 and ATF3 delta zip transcriptional repression versus activation by alternatively spliced isoforms. J. Biol. Chem. 1994, 269:15819-15826.
12. Dovio A., Sartori M.L., Masera R.G., Ceoloni B., Reimondo G., Prolo P., Racca S., Angeli A. Autocrine down-regulation of glucocorticoid receptors by interleukin-11 in human osteoblast-like cell lines. J. Endocrinol. 2003, 177:109-117.
13. Du X.X., Williams D.A. Interleukin-11; a multifunctional growth factor derived from the hematopoietic microenvironment. Blood 1994, 83:2023-2030.
14. Du X.X., Williams D.A. Interleukin-11; review of molecular, cell biology, and clinical use. Blood 1997, 89:3897-3908.
15. Dwarki V.J., Montminy M., Verma I.M. Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. EMBO J. 1990, 9:225-232.
16. Fisher L.W., McBride O.W., Termine J.D., Young M.F. Human bone sialoprotein. J. Biol. Chem. 1990, 265:2347-2351.
17. Ganss B., Kim R.H., Sodek J. Bone sialoprotein. Crit. Rev. Oral Biol. Med. 1999, 10:79-98.
18. Gimble J.M., Wanker F., Wang C.S., Bas H., Wu X., Kelly K., Yancopoulos G.D., Hill M.R. Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein. J. Cell. Biochem. 1994, 54:122-133.
19. Girasole G., Passeri G., Jilka R.L., Manolagas S.C. Interleukin-11: a new cytokine critical for osteoclast development. J. Clin. Invest. 1994, 93:1516-1524.
20. Hassan M.Q., Tare R.S., Lee S.H., Mandeville M., Morasso M.I., Javed A., van Wijnen A.J., Stein J.L., Stein G.S., Lian J.B. BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network. J. Biol. Chem. 2006, 281:40515-40526.
21. Hill P.A., Tumber A., Papaioannou S., Meikle M.C. The cellular actions of interleukin-11 on bone resorption in vitro. Endocrinol. 1998, 139:1564-1572.
22. Hunter G.K., Goldberg H.A. Nucleation of hydroxyapatite by bone sialoprotein. Proc. Natl Acad. Sci. U. S. A. 1993, 90:8562-8565.
23. Ibrahim T., Leong I., Sanchez-Sweatman O., Khokha R., Sodek J., Tenenbaum H.C., Ganss B., Cheifetz S. Expression of bone sialoprotein and osteopontin in breast cancer bone metastases. Clin. Exp. Metastasis 2000, 18:253-260.
24. Jheon A., Bansal A.K., Zhu B., Ganss B., Cheifetz S., Sodek J. Characterisation of the constitutive over-expression of AJ18 in a novel rat stromal bone marrow cell line (D8-SBMC). Arch. Oral Biol. 2009, 54:705-716.
25. Johnson R.B., Wood N., Serio F.G. Interleukin-11 and IL-17 and the pathogenesis of periodontal disease. J. Periodontol. 2004, 75:37-43.
26. Keller D.C., Du X.X., Srour E.F., Hoffman R., Williams D.A. Interleukin-11 inhibits adipogenesis and stimulates myelopoiesis in human long-term marrow cultures. Blood 1993, 82:1428-1435.
27. Kerr J.M., Fisher L.W., Termine J.D., Wang M.G., Mcbride O.W., Young M.F. The human bone sialoprotein gene (IBSP): genomic localization and characterization. Genomics 1993, 17:408-415.
28. Kim R.H., Sodek J. Transcription of the bone sialoprotein gene is stimulated by v-Src acting through an inverted CCAAT box. Cancer Res. 1999, 59:565-571.
29. Kim R.H., Shapiro H.S., Li J.J., Wrana J.L., Sodek J. Characterization of the human bone sialoprotein (BSP) gene and its promoter sequence. Matrix Biol. 1994, 14:31-40.
30. Kiyoshima T., Yamauchi M., Wong C., Jheon A., Ganss B., Sodek J. An L1 element disrupts human bone sialoprotein promoter: lack of tissue-specific regulation by distalless5 (Dlx5) and runt homeodomain protein 2 (Runx2)/core binding factor a1 (Cbfa1) elements. Gene 2002, 299:205-217.
31. Komori T., Yagi H., Nomura S., Yamaguchi A., Sasaki K., Deguchi K., Shimizu Y., Bronson R.T., Gao Y.H., Inada M., Sato M., Okamoto R., Kitamura Y., Yoshiki S., Kishimoto T. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997, 89:755-764.
32. Laoide B.M., Foulkes N.S., Schlotter F., Sassone-Corsi P. The functional versatility of CREM is determined by its modular structure. EMBO J. 1993, 12:1179-1191.
33. Leon E.R., Iwasaki K., Komaki M., Kojima T., Ishikawa I. Osteogenic effect of interleukin-11 and synergism with ascorbic acid in human periodontal ligament cells. J. Perio. Res. 2007, 42:527-535.
34. Li J.J., Sodek J. Cloning and characterization of the rat bone sialoprotein gene promoter. Biochem. J. 1993, 289:625-629.
35. Li J.J., Kim R.H., Sodek J. An inverted TATA box directs downstream transcription of the bone sialoprotein gene. Biochem. J. 1995, 310:33-40.
36. Li X., Kato N., Mezawa M., Li Z., Wang Z., Yang L., Sasaki Y., Kaneko T., Takai H., Yoshimura A., Ogata Y. Transcriptional regulation of bone sialoprotein gene by Porphyromonas gingivalis lipopolysaccharide. J. Cell. Biochem. 2010, 110:823-833.
37. Littlewood A.J., Russell J., Harvey G.R., Hughes D.E., Russell R.G., Gowen M. The modulation of the expression of IL-6 and its receptor in human osteoblasts in vitro. Endocrinology 1991, 129:1513-1520.
38. Lowik C.W., van der Pluijm G., Bloys H., Hoekman K., Bijvoet O.L.M., Aarden L.A., Papapoulos S.E. Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis. Biochem. Biophys. Res. Commun. 1989, 162:1546-1552.
39. Mehler M.F., Rozental R., Dougherty M., Spray D.C., Kessler J.A. Cytokine regulation of neuronal differentiation of hippocampal progenitor cells. Nature 1993, 362:62-65.
40. Mezawa M., Araki S., Takai H., Sasaki Y., Wang S., Li X., Kim D.S., Nakayama Y., Ogata Y. Regulation of human bone sialoprotein gene transcription by platelet-derived growth factor-BB. Gene 2009, 435:80-87.
41. Musashi M., Yang Y.C., Paul S.R., Clark S.C., Sudo T., Ogawa M. Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture. Proc. Natl Acad. Sci. U. S. A. 1991, 88:765-769.
42. Nakashima K., Zhou X., Kunkel G., Zhang Z., Min Deng J., Behringer R.R., de Crombrugghe B. The Novel zinc finger-containing transcription factor is required for osteoblast differentiation and bone formation. Cell 2002, 108:17-29.
43. Nakayama Y., Nakajima Y., Kato N., Takai H., Kim D., Arai M., Mezawa M., Araki S., Sodek J., Ogata Y. Insulin-like growth factor-I increases bone sialoprotein (BSP) expression through fibroblast growth factor-2 response element and homeodomain protein-binding site in the proximal promoter of the BSP gene. J. Cell. Physiol. 2006, 208:326-335.
44. Nash R.A., Seidel K., Storb R., Slichter S., Schuening F.G., Appelbaum F.R., Becker A.B., Bolles L., Deeg H.J., Graham T., Hackman R.C., Burstein S.A. Effects of rhIL-11 on normal dogs and after sublethal radiation. Exp. Hematol. 1995, 23:389-396.
45. Neben T.Y., Loebelenz J., Hayes L., Mccarthy K., Stoudemire J., Schaub R., Goldman S.J. Recombinant human interleukin-11 stimulates megakaryocytopoiesis and increases peripheral platelets in normal and splenectomized mice. Blood 1993, 81:901-908.
46. Newberry E.P., Latifi T., Towler D.A. Reciprocal regulation of osteocalcin transcription by the homeodomain proteins. Biochemistry 1998, 37:16360-16368.
47. Ogata Y. Bone sialoprotein and its transcriptional regulatory mechanism. J. Perio. Res. 2008, 43:127-135.
48. Ogata Y., Yamauchi M., Kim R.H., Li J.J., Freedman L.P., Sodek J. Glucocorticoid regulation of bone sialoprotein (BSP) gene expression: identification of a glucocorticoid response element in the bone sialoprotein gene promoter. Eur. J. Biochem. 1995, 230:183-192.
49. Ogata Y., Niisato N., Furuyama S., Cheifetz S., Kim R.H., Sugiya H., Sodek J. Transforming growth factor-β1 regulation of bone sialoprotein gene transcription: identification of a TGF-β activation element in the rat BSP gene promoter. J. Cell. Biochem. 1997, 65:501-512.
50. Ogata Y., Nakao S., Kim R.H., Li J.J., Furuyama S., Sugiya H., Sodek J. Parathyroid hormone regulation of bone sialoprotein (BSP) gene transcription is mediated through a pituitary specific transcription factor-1 (Pit-1) motif in the rat BSP gene promoter. Matrix Biol. 2000, 19:395-407.
51. Oldberg Å., Franzen A., Heinegård D. The primary structure of a cell-binding bone sialoprotein. J. Biol. Chem. 1988, 263:19430-19432.
52. Paul S.R., Bennett F., Calvetti J.A., Kelleher K., Wood C.R., O'Hare R.M., Leary A.C., Sibley B., Clark S.C., Williams D.A., Yang Y.C. Molecular cloning of a cDNA encoding interleukin-11, a stromal cell derived lymphopoietic cytokine. Proc. Natl Acad. Sci. U. S. A. 1990, 87:7512-7516.
53. Poli V., Mancini F.P., Cortese R. IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Cell 1990, 63:643-653.
54. Reid I.R., Lowe C., Cornish J., Skinner S.J.M., Hilton D.J., Willson T.A., Gearing D.P., Martin T.J. Leukemia inhibitory factor: a novel bone-active cytokine. Endocrinol. 1990, 126:1416-1420.
55. Samee N., de Vernejoul M.C., Levi G. Role of DLX regulatory proteins in osteogenesis and chondrogenesis. Crit. Rev. Eukaryot. Gene Expr. 2007, 17:173-186.
56. Samoto H., Shimizu E., Matsuda-Honjyo Y., Saito R., Nakao S., Yamazaki M., Furuyama S., Sugiya H., Sodek J., Ogata Y. Prostaglandin E2 stimulates bone sialoprotein (BSP) expression through cAMP and FGF2 response elements in the proximal promoter of the rat BSP gene. J. Biol. Chem. 2003, 278:28659-28667.
57. Sassone-Corsi P. Transcription factors responsive to cAMP. Annu. Rev. Cell Dev. Biol. 1995, 11:355-377.
58. Schlerman F.J., Bree A.G., Kaviani M.D., Nagle S.L., Donnelly L.H., Mason L.E., Schaub R.G., Grupp S.A., Goldman S.J. Thrombopoietic activity of recombinant human interleukin 11 (rHuIL-11) in normal and myelosuppressed nonhuman primates. Stem Cells 1996, 14:517-532.
59. Shimizu E., Nakayama Y., Nakajima Y., Kato N., Takai H., Kim D.S., Arai M., Saito R., Sodek J., Ogata Y. Fibroblast growth factor 2 and cyclic AMP synergistically regulate bone sialoprotein gene expression. Bone 2006, 39:42-52.
60. Shimizu-Sasaki E., Yamazaki M., Furuyama S., Sugiya H., Sodek J., Ogata Y. Identification of a novel response element in the rat bone sialoprotein (BSP) gene promoter that mediates constitutive and fibroblast growth factor 2-induced expression of BSP. J. Biol. Chem. 2001, 276:5459-5466.
61. Shirakabe K., Terasawa K., Miyama K., Shibuya H., Nishida E. Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5. Genes Cells 2001, 6:851-856.
62. Suga K., Saitoh M., Fukushima S., Takahashi K., Nara H., Yasuda S., Miyata K. Interleukin-11 induces osteoblast differentiation and acts synergistically with bone morphogenetin protein-2 in C3H10T1/2 cells. J. Interferon Cytokine Res. 2001, 21:695-707.
63. Suga K., Saitoh M., Kokubo S., Fukushima S., Kaku S., Yasuda S., Miyata K. Interleukin-11 acts synergistically with bone morphogenetic protein-2 to accelerate bone formation in a rat ectopic model. J. Interferon Cytokine Res. 2003, 23:203-207.
64. Takeuchi Y., Watanabe S., Ishii G., Takeda S., Nakayama K., Fukumoto S., Kaneta Y., Inoue D., Matsumoto T., Harigaya K., Fujita T. Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice. J. Biol. Chem. 2002, 277:49011-49018.
65. Tenney R., Stansfield K., Pekala P.H. Interleukin 11 signaling in 3T3-L1 adipocytes. J. Cell. Physiol. 2005, 202:160-166.
66. Teramura M., Kobayashi S., Hoshino S., Oshimi K., Mizoguchi H. Interleukin-11 enhances human megakaryocytopoiesis in vitro. Blood 1992, 79:327-331.
67. Teramura M., Kobayashi S., Yoshinaga K., Iwabe K., Mizoguchi H. Effect of interleukin 11 on normal and pathological thrombopoiesis. Cancer Chemother. Pharmacol. 1996, 38(suppl):S99-S102.
68. Trepicchio W.L., Bozza M., Pedneault G., Dorner A.J. Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J. Immunol. 1996, 157:3627-3634.
69. Waltregny D., Bellahcène A., Leval X.D., Florkin B., Weidle U., Castronovo V. Increased expression of bone sialoprotein in bone metastases compared with visceral metastases in human breast and prostate cancers. J. Bone Miner. Res. 2000, 15:834-843.
70. Wang Z., Li X., Li Z., Yang L., Sasaki Y., Wang S., Zhou L., Araki S., Mezawa M., Takai H., Ogata Y. Effects of inorganic polyphosphate on bone sialoprotein gene expression. Gene 2010, 452:79-86.
71. Yamauchi M., Ogata Y., Kim R.H., Li J.J., Freedman L.P., Sodek J. AP-1 regulation of the rat bone sialoprotein gene transcription is mediated through a TPA response element within a glucocorticoid response unit in the gene promoter. Matrix Biol. 1996, 15:119-130.
72. Yang L., Takai H., Utsunomiya T., Li X., Li Z., Wang Z., Wang S., Sasaki Y., Yamamoto H., Ogata Y. Kaempferol stimulates bone sialoprotein gene transcription and new bone formation. J. Cell. Biochem. 2010, 110:1342-1355.
73. Yin T.G., Schendel P., Yang Y.C. Enhancement of in vitro and in vivo antigen-specific antibody responses by interleukin 11. J. Exp. Med. 1992, 175:211-216.
74. Yonemura Y., Kawakita M., Masuda T., Fujimoto K., Kato K., Takatsuki K. Synergistic effects of interleukin 3 and interleukin 11 on murine megakaryopoiesis in serum-free culture. Exp. Hematol. 1992, 20:1011-1016.
75. Yonemura Y., Kawakita M., Masudo T., Fujimoto K., Takatsuki K. Effect of recombinant human interleukin-11 on rat megakaryopoiesis and thrombopoiesis in vivo: comparative study with interleukin-6. Br. J. Haematol. 1993, 84:16-23.