Substance P-induced skin inflammation is not modulated by a single dose of sitagliptin in human volunteers

Biological Chemistry

Volumn 392, Issue 3, 2011, Pages 217-221

  Grouzmann, Eric ^a   Bigliardi, Paul ^a   Appenzeller, Monique ^a   Pannatier, André ^a   Buclin, Thierry ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Clinical trial; Dipeptidylpeptidase IV; Flare; Proteases; Tachykinin; Wheal

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL PEPTIDASE IV; MEMBRANE METALLOENDOPEPTIDASE; SITAGLIPTIN; SUBSTANCE P; CAPSAICIN; DIPEPTIDYL PEPTIDASE IV INHIBITOR; PYRAZINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ADULT; ARTICLE; BURNING SENSATION; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG DOSE INCREASE; ENZYME ACTIVITY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; SKIN INFLAMMATION; URTICARIA; BLOOD; CARBONATED BEVERAGE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOSE RESPONSE; DRUG EFFECT; DRUG ERUPTION; EDEMA; ERYTHEMA; INTRADERMAL DRUG ADMINISTRATION; SKIN; VASODILATATION;

CAPSAICIN; CARBONATED BEVERAGES; CROSS-OVER STUDIES; DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ERUPTIONS; EDEMA; ERYTHEMA; HUMANS; INJECTIONS, INTRADERMAL; MALE; PAIN; PYRAZINES; SKIN; SUBSTANCE P; TRIAZOLES; VASODILATION;

EID: 79953328386     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2011.003     Document Type: Article

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