Effects of exogenous glucocorticoid on combat-related PTSD symptoms

Annals of Clinical Psychiatry

Volumn 22, Issue 4, 2010, Pages 274-279

  Surís, Alina ^a   North, Carol ^a   Adinoff, Bryon ^a   Powell, Craig M ^b   Greene, Robert ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Glucocorticoids; Memory extinction; Pharmacotherapy; Posttraumatic stress disorder

Indexed keywords

GLUCOCORTICOID; HYDROCORTISONE SODIUM SUCCINATE; PLACEBO; SODIUM CHLORIDE; ANXIOLYTIC AGENT; HYDROCORTISONE;

ABSENCE OF SIDE EFFECTS; AMNESIA; ARTICLE; AVOIDANCE BEHAVIOR; BATTLE INJURY; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; HUMAN; IMAGERY; MALE; MEMORY; MEMORY CONSOLIDATION; OUTCOME ASSESSMENT; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; SYMPTOM; TREATMENT INDICATION; VETERAN; VISUAL MEMORY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL RATING SCALE; SOLDIER; TIME;

ANTI-ANXIETY AGENTS; COMBAT DISORDERS; DOUBLE-BLIND METHOD; HUMANS; HYDROCORTISONE; MALE; MEMORY; MILITARY PERSONNEL; PSYCHIATRIC STATUS RATING SCALES; STRESS DISORDERS, POST-TRAUMATIC; TIME FACTORS;

EID: 79953324790     PISSN: 10401237     EISSN: 15473325     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Kessler RC, Sonnega A, Bromet E, et al. Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry. 1995;52:1048-1060.
2. Institute of Medicine, Committee on Treatment of Posttraumatic Stress Disorder. Treatment of posttraumatic stress disorder: an assessment of the evidence. Washington, DC: National Academies Press; 2008.
3. Schnurr PP, Friedman MJ, Engel CC, et al. Cognitive behavioral therapy for posttraumatic stress disorder in women: a randomized controlled trial. JAMA. 2007;297:820-830. (Pubitemid 46333947)
4. Foa EB, Hembree EA, Cahill SP, et al. Randomized trial of prolonged exposure for posttraumatic stress disorder with and without cognitive restructuring: outcome at academic community clinics. J Consult Clin Psychol. 2005;79:953-964. (Pubitemid 41643245)
5. Bryant RA, Moulds ML, Guthrie RM, et al. Imaginal exposure alone and imaginal exposure with cognitive restructuring in treatment of posttraumatic stress disorder. J Consult Clin Psychol. 2003;71:706-712. (Pubitemid 36897404)
6. Rescorla RA. Experimental extinction. In: Mowrer RR, Klein SB, eds. Handbook of contemporary learning theories. Mahwah, NJ: Lawrence Erlbaum Associated, Inc.; 2001:119-154.
7. Bouton ME. Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. Psychol Bull. 1993;114:80-99.
8. Myers KM, Davis M. Behavioral and neural analysis of extinction. Neuron. 2002;36:567-584. (Pubitemid 35346753)
9. Cai WH, Blundell J, Han J, et al. Postreactivation glucocorticoids impair recall of established fear memory. J Neurosci. 2006;26:9560-9566. (Pubitemid 44396869)
10. Yang YL, Chao PK, Lu KT. Systemic and intra-amygdala administration of glucocorticoid agonist and antagonist modulate extinction of conditioned fear. Neuropsychopharmacology. 2006;31:912-924.
11. Abrari K, Rashidy-Pour A, Semnanian S, et al. Administration of corticosterone after memory reactivation disrupts subsequent retrieval of a contextual conditioned fear memory: dependence upon training intensity. Neurobiol Learn Mem. 2008;89:178-184. (Pubitemid 350235967)
12. Yehuda R. Biology of posttraumatic stress disorder. J Clin Psychiatry. 2001;62(suppl 17):41-46. (Pubitemid 32720665)
13. Newport DJ, Nemeroff CB. Neurobiology of post-traumatic stress disorder. Curr Opin Neurobiol. 2000; 10:211-218.
14. Schelling G, Stoll C, Kapfhammer HP, et al. The effect of stress doses of hydrocortisone during septic shock on posttraumatic stress disorder and health-related quality of life in survivors. Crit Care Med. 1999;27:2678-2683. (Pubitemid 30027180)
15. de Quervain DJ. Glucocorticoid-induced reduction of traumatic memories: implications for the treatment of PTSD. Prog Brain Res. 2008;167:239-247.
16. Diergaarde L, Schoffelmeer AN, De Vries TJ. Pharmacological manipulation of memory reconsolidation: towards a novel treatment of pathogenic memories. Eur J Pharmacology. 2008;585:453-457.
17. Blake DD, Weathers FW, Nagy LM, et al. A clinician rating scale for assessing current and lifetime PTSD: the CAPS-1. Behavior Therapist. 1990;13:187-188.
18. First MB, Gibbon M, Spitzer RL, et al. User's guide for the Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Research Version. New York, NY: Biometrics Research; 2001.
19. Weiss DS, Marmar CR. The Impact of Event Scale-Revised. In: Assessing psychological trauma and PTSD. Wilson JP, Keane TM, eds. New York, NY: Guilford Press; 1997:399-411.
20. Rush AJ, Trivedi MH, Ibrahim HM, et al. The 16-item Quick Inventory of Depressive Symptomatology (QIDS) Clinician Rating (QIDS-C) and Self-Report (QIDS-SR): a psychometric evaluation in patients with chronic major depression. Biol Psychiatry. 2003;54:573-583. (Pubitemid 37289444)
21. Pitman RK, Orr SP, Forgue DF, et al. Psychophysiologic assessment of posttraumatic stress disorder imagery in Vietnam combat veterans. Arch Gen Psychiatry. 1987;44:970-975. (Pubitemid 18009652)
22. North CS, Nixon SJ, Shariat S, et al. Psychiatric disorders among survivors of the Oklahoma City bombing. JAMA. 1999;282:755-762. (Pubitemid 29404382)
23. Ehlers A, Mayou RA, Bryant B. Psychological predictors of chronic posttraumatic stress disorder after motor vehicle accidents. J Abnorm Psychol. 1998;107:508-519. (Pubitemid 28369259)
24. Maes M, Delmeire L, Schotte C, et al. Epidemiologic and phenomenological aspects of post-traumatic stress disorder: DSM-III-R diagnosis and diagnostic criteria not validated. Psychiatry Res. 1998;81:179-193. (Pubitemid 28526974)
25. Foa E. Psychosocial therapy for posttraumatic stress disorder. J Clin Psychiatry. 2006;67(suppl 2):40-45. (Pubitemid 43268188)