Consistency of the disposition index in the face of diet induced insulin resistance: Potential role of FFA

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Stefanovski, Darko ^a   Richey, Joyce M ^a   Woolcott, Orison ^a   Lottati, Maya ^a   Zheng, Dan ^a   Harrison, Lisa N ^a   Ionut, Viorica ^a   Kim, Stella P ^a   Hsu, Isabel ^a   Bergman, Richard N ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; INSULIN;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; DISPOSITION INDEX; DOG; FATTY ACID BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MALE; METABOLIC CLEARANCE RATE; METABOLIC PARAMETERS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; SIGNAL TRANSDUCTION; WEIGHT GAIN; ANIMAL; BLOOD; BODY COMPOSITION; BODY WEIGHT; DARKNESS; DIET; DIET RESTRICTION; FEEDING BEHAVIOR; GLUCOSE TOLERANCE TEST; METABOLISM; NONPARAMETRIC TEST; SECRETION; TIME;

CANIS FAMILIARIS;

ANIMALS; BLOOD GLUCOSE; BODY COMPOSITION; BODY WEIGHT; DARKNESS; DIET; DOGS; FASTING; FATTY ACIDS, NONESTERIFIED; FEEDING BEHAVIOR; GLUCOSE TOLERANCE TEST; INSULIN; INSULIN RESISTANCE; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 79953304739     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018134     Document Type: Article

References (34)

1. Bergman RN, Phillips LS, Cobelli C, (1981) Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 68: 1456-1467.
2. Stumvoll M, Tataranni PA, Bogardus C, (2005) The hyperbolic law-a 25-year perspective. Diabetologia 48: 207-209.
3. Ferrannini E, Barrett EJ, Bevilacqua S, DeFronzo RA, (1983) Effect of fatty acids on glucose production and utilization in man. J Clin Invest 72: 1737-1747.
4. Maheux P, Jeppesen J, Sheu WH, Hollenbeck CB, Clinkingbeard C, et al. (1994) Additive effects of obesity, hypertension, and type 2 diabetes on insulin resistance. Hypertension 24: 695-698.
5. Mittelman SD, Van Citters GW, Kim SP, Davis DA, Dea MK, et al. (2000) Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes 49: 2116-2125.
6. Terauchi Y, Takamoto I, Kubota N, Matsui J, Suzuki R, et al. (2007) Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance. J Clin Invest 117: 246-257.
7. Weir GC, Bonner-Weir S, (2007) A dominant role for glucose in beta cell compensation of insulin resistance. J Clin Invest 117: 81-83.
8. Festa A, D'Agostino R Jr, Hanley AJ, Karter AJ, Saad MF, et al. (2004) Differences in insulin resistance in nondiabetic subjects with isolated impaired glucose tolerance or isolated impaired fasting glucose. Diabetes 53: 1549-1555.
9. Hanefeld M, Koehler C, Fuecker K, Henkel E, Schaper F, et al. (2003) Insulin secretion and insulin sensitivity pattern is different in isolated impaired glucose tolerance and impaired fasting glucose: the risk factor in Impaired Glucose Tolerance for Atherosclerosis and Diabetes study. Diabetes Care 26: 868-874.
10. Steil GM, Trivedi N, Jonas JC, Hasenkamp WM, Sharma A, et al. (2001) Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression. Am J Physiol Endocrinol Metab 280: E788-E796.
11. Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF, (2000) Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes 49: 399-408.
12. Kim SP, Catalano KJ, Hsu IR, Chiu JD, Richey JM, et al. (2007) Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. Am J Physiol Endocrinol Metab 292: E1590-E1598.
13. Morgan LM, Aspostolakou F, Wright J, Gama R, (1999) Diurnal variations in peripheral insulin resistance and plasma non-esterified fatty acid concentrations: a possible link? Ann Clin Biochem 36 (Pt 4): 447-450.
14. Bergman RN, Ider YZ, Bowden CR, Cobelli C, (1979) Quantitative estimation of insulin sensitivity. Am J Physiol 236: E667-E677.
15. Pacini G, Bergman RN, (1986) MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed 23: 113-122.
16. Kim SP, Ellmerer M, Van Citters GW, Bergman RN, (2003) Primacy of hepatic insulin resistance in the development of the metabolic syndrome induced by an isocaloric moderate-fat diet in the dog. Diabetes 52: 2453-2460.
17. Polonsky KS, Pugh W, Jaspan JB, Cohen DM, Karrison T, et al. (1984) C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog. J Clin Invest 74: 1821-1829.
18. Rocchini AP, Marker P, Cervenka T, (1997) Time course of insulin resistance associated with feeding dogs a high-fat diet. Am J Physiol 272: E147-E154.
19. Richey JM, Woolcott OO, Stefanovski D, Harrison LN, Zheng D, et al. (2009) Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs. Am J Physiol Endocrinol Metab 296: E1311-E1318.
20. Miles JM, Wooldridge D, Grellner WJ, Windsor S, Isley WL, et al. (2003) Nocturnal and postprandial free fatty acid kinetics in normal and type 2 diabetic subjects: effects of insulin sensitization therapy. Diabetes 52: 675-681.
21. Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M, (2006) Fatty acid signaling in the beta-cell and insulin secretion. Diabetes 55 (Suppl 2): S16-S23.
22. Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, et al. (2003) Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 422: 173-176.
23. Tasali E, Van Cauter E, (2002) Sleep-disordered breathing and the current epidemic of obesity: consequence or contributing factor? Am J Respir Crit Care Med 165: 562-563.
24. Kabir M, Catalano KJ, Ananthnarayan S, Kim SP, Van Citters GW, et al. (2005) Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. Am J Physiol Endocrinol Metab 288: E454-E461.
25. Bergman RN, Kim SP, Catalano KJ, Hsu IR, Chiu JD, et al. (2006) Why visceral fat is bad: mechanisms of the metabolic syndrome. Obesity (Silver Spring) 14 (Suppl 1): 16S-19S.
26. Boden G, (1998) Free fatty acids (FFA), a link between obesity and insulin resistance. Front Biosci 3: d169-d175.
27. Accili D, (2004) Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic. Diabetes 53: 1633-1642.
28. Julius S, Valentini M, (1998) Consequences of the increased autonomic nervous drive in hypertension, heart failure and diabetes. Blood Press Suppl 3 pp. 5-13.
29. Getty L, Panteleon AE, Mittelman SD, Dea MK, Bergman RN, (2000) Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo. J Clin Invest 106: 421-430.
30. Wilding JP, (2007) The importance of free fatty acids in the development of Type 2 diabetes. Diabet Med 24: 934-945.
31. Dai T, Abou-Rjaily GA, Al Share' QY, Yang Y, Fernstrom MA, et al. (2004) Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice. J Biol Chem 279: 45155-45161.
32. Kim SP, Ellmerer M, Kirkman EL, Bergman RN, (2007) beta-Cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model. Am J Physiol Endocrinol Metab 292: E1581-E1589.
33. Rebrin K, Steil GM, Getty L, Bergman RN, (1995) Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes 44: 1038-1045.
34. Stein DT, Esser V, Stevenson BE, Lane KE, Whiteside JH, et al. (1996) Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. J Clin Invest 97: 2728-2735.