Positive correlation between beta-3-adrenergic receptor (ADRB3) gene and gout in a Chinese male population

Journal of Rheumatology

Volumn 38, Issue 4, 2011, Pages 738-740

  Wang, Binbin ^a,b,c   Meng, Dongmei ^a   Wang, Jing ^b,c   Jia, Zhaotong ^a   Zhoub, Sirui ^b   Liu, Shiguo ^a   Chu, Nan ^a   Han, Lin ^a   Zhang, Kun ^a   Ma, Xu ^b,c   Li, Changgui ^a  

^a QINGDAO UNIVERSITY   (China)

^b NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^c GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

ADRB3; Association analysis; Beta 3 adrenergic receptor; Hyperuricemia gout

Indexed keywords

ARGININE; BETA 3 ADRENERGIC RECEPTOR; CHOLESTEROL; TRYPTOPHAN; URIC ACID;

ADULT; AGE; ALLELE; ARTICLE; BODY MASS; CASE CONTROL STUDY; CHINESE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; GOUT; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; POPULATION GENETICS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; GENE FREQUENCY; GENOTYPE; GOUT; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RECEPTORS, ADRENERGIC, BETA-3; URIC ACID;

EID: 79953300287     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.101037     Document Type: Article

References (12)

1. Ringel J, Kreutz R, Distler A, Sharma AM. The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with hypertension in men with type 2 diabetes mellitus. Am J Hypertens 2000;13:1027-31.
2. Garcia-Rubi E, Starling RD, Tchernof A, Matthews DE, Walston JD, Shuldiner AR, et al. Trp64Arg variant of the beta-3-adrenoceptor and insulin resistance in obese postmenopausal women. J Clin Endocrinol Metab 1998;83:4002-5. (Pubitemid 28513587)
3. Choi HK, Mount DB, Reginato AM. Pathogenesis of gout. Ann Intern Med 2005;143:499-516. (Pubitemid 41379398)
4. Schumacher HR Jr. The pathogenesis of gout. Cleve Clin J Med 2008;75 Suppl 5:S2-4.
5. Walston J, Silver K, Bogardus C, et al. Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene. N Engl J Med 1995;333:343-7.
6. McFarlane-Anderson N, Bennett F, Wilks R, Howell S, Newsome C, Cruickshank K, et al. The Trp64Arg mutation of the beta 3-adrenergic receptor is associated with hyperglycemia and current body mass index in Jamaican women. Metabolism 1998;47:617-21. (Pubitemid 28213125)
7. Widen E, Lehto M, Kanninen T, Walston J, Shuldiner AR, Groop LC. Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. N Engl J Med 1995;333:348-51.
8. Wallace SL, Robinson H, Masi AT, Decker JL, McCarty DJ, Yü TF. Preliminary criteria for the classification of the acute arthritis of primary gout. Arthritis Rheum 1977;20:895-900.
9. Morcillo S, Rojo-Martínez G, Martín-Núñez GM, Gómez-Zumaquero JM, García-Fuentes E, Ruiz de Adana M, et al. Trp64Arg polymorphism of the ADRB3 gene predicts hyperuricemia risk in a population from southern Spain. J Rheumatol 2010;37:417-21.
10. Rho YH, Choi SJ, Lee YH, Ji JD, Song GG. The association between hyperuricemia and the W64R polymorphism of the beta-3 adrenergic receptor. Rheumatol Int 2007;27:835-9. (Pubitemid 46906636)
11. Wang G, Li Q, Niu T, Chen C, Xu X. Association of GYS1 and β3-AR gene with postprandial hyperglycemia and serum uric acid in type 2 diabetes mellitus. Chin Med J Engl 2002;115:1308-11.
12. Piétri-Rouxel F, St. John Manning B, Gros J, Strosberg AD. The biochemical effect of the naturally occurring Trp64>Arg mutation on human beta 3-adrenoceptor activity. Eur J Biochem 1997;247:1174-9. (Pubitemid 27337075)