-
2
-
-
52949132229
-
Combating HIV resistance - focus on darunavir
-
Tremblay CL. Combating HIV resistance - focus on darunavir. Ther Clin Risk Manag 2008; 4: 759-766.
-
(2008)
Ther Clin Risk Manag
, vol.4
, pp. 759-766
-
-
Tremblay, C.L.1
-
3
-
-
34047207229
-
Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2
-
Lancet
-
Clotet B, Bellos N, Molina JM et al. Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials. Lancet 2007; 369: 1169-1178.
-
(2007)
a pooled subgroup analysis of data from two randomised trials
, vol.369
, pp. 1169-1178
-
-
Clotet, B.1
Bellos, N.2
Molina, J.M.3
-
4
-
-
34347329093
-
Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN
-
Lancet
-
Madruga JV, Berger D, McMurchie M et al. Efficacy and safety of darunavir-ritonavir compared with that of lopinavir-ritonavir at 48 weeks in treatment-experienced, HIV-infected patients in TITAN: a randomised controlled phase III trial. Lancet 2007; 370: 49-58.
-
(2007)
a randomised controlled phase III trial
, vol.370
, pp. 49-58
-
-
Madruga, J.V.1
Berger, D.2
McMurchie, M.3
-
5
-
-
49649092719
-
Efficacy and safety of once-daily darunavir/ritonavir versus lopinavir/ritonavir in treatment-naive HIV-1-infected patients at week 48
-
Ortiz R, Dejesus E, Khanlou H et al. Efficacy and safety of once-daily darunavir/ritonavir versus lopinavir/ritonavir in treatment-naive HIV-1-infected patients at week 48. AIDS 2008; 22: 1389-1397.
-
(2008)
AIDS
, vol.22
, pp. 1389-1397
-
-
Ortiz, R.1
Dejesus, E.2
Khanlou, H.3
-
6
-
-
36549014231
-
Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients
-
Youle M. Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients. J Antimicrob Chemother 2007; 60: 1195-1205.
-
(2007)
J Antimicrob Chemother
, vol.60
, pp. 1195-1205
-
-
Youle, M.1
-
7
-
-
34347327010
-
Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1
-
Lancet
-
Madruga JV, Cahn P, Grinsztejn B et al. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial. Lancet 2007; 370: 29-38.
-
(2007)
24-week results from a randomised, double-blind, placebo-controlled trial
, vol.370
, pp. 29-38
-
-
Madruga, J.V.1
Cahn, P.2
Grinsztejn, B.3
-
8
-
-
34347354196
-
Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2
-
Lancet
-
Lazzarin A, Campbell T, Clotet B et al. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial. Lancet 2007; 370: 39-48.
-
(2007)
24-week results from a randomised, double-blind, placebo-controlled trial
, vol.370
, pp. 39-48
-
-
Lazzarin, A.1
Campbell, T.2
Clotet, B.3
-
9
-
-
47949114939
-
Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection
-
Cooper DA, Steigbigel RT, Gatell JM et al. Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection. N Engl J Med 2008; 359: 355-365.
-
(2008)
N Engl J Med
, vol.359
, pp. 355-365
-
-
Cooper, D.A.1
Steigbigel, R.T.2
Gatell, J.M.3
-
10
-
-
33845971010
-
The pathway leading to TMC114 resistance is different for TMC114 compared with other protease inhibitors
-
De Meyer S, Azijn H, Fransen E et al. The pathway leading to TMC114 resistance is different for TMC114 compared with other protease inhibitors. Antivir Ther 2006; 11: S24.
-
(2006)
Antivir Ther
, vol.11
-
-
De Meyer, S.1
Azijn, H.2
Fransen, E.3
-
12
-
-
70349189262
-
Phenotypic and genotypic determinants of resistance to darunavir
-
Antivir Ther ;
-
De Meyer S, Dierynck I, Lathouwers E et al. Phenotypic and genotypic determinants of resistance to darunavir: analysis of data from treatment-experienced patients in POWER 1, 2, 3 and DUET-1 and 2. Antivir Ther 2008; 13: A33.
-
(2008)
analysis of data from treatment-experienced patients in POWER 1, 2, 3 and DUET-1 and 2
, vol.13
-
-
De Meyer, S.1
Dierynck, I.2
Lathouwers, E.3
-
13
-
-
55049134097
-
Resilience to resistance of HIV-1 protease inhibitors
-
AIDS Rev
-
Lefebvre E, Schiffer CA. Resilience to resistance of HIV-1 protease inhibitors: profile of darunavir. AIDS Rev 2008; 10: 131-142.
-
(2008)
profile of darunavir
, vol.10
, pp. 131-142
-
-
Lefebvre, E.1
Schiffer, C.A.2
-
14
-
-
60749130473
-
Mutations associated with virological response to darunavir/ritonavir in HIV-1-infected protease inhibitor-experienced patients
-
Descamps D, Lambert-Niclot S, Marcelin AG et al. Mutations associated with virological response to darunavir/ritonavir in HIV-1-infected protease inhibitor-experienced patients. J Antimicrob Chemother 2009; 63: 585-592.
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 585-592
-
-
Descamps, D.1
Lambert-Niclot, S.2
Marcelin, A.G.3
-
15
-
-
34548749164
-
Prevalence of darunavir resistance mutations in HIV-1-infected patients failing other protease inhibitors
-
Poveda E, de Mendoza C, Martin-Carbonero L et al. Prevalence of darunavir resistance mutations in HIV-1-infected patients failing other protease inhibitors. J Antimicrob Chemother 2007; 60: 885-888.
-
(2007)
J Antimicrob Chemother
, vol.60
, pp. 885-888
-
-
Poveda, E.1
de Mendoza, C.2
Martin-Carbonero, L.3
-
16
-
-
78149370844
-
Cohort profile
-
The Swiss HIV Cohort Study. Int J Epidemiol
-
The Swiss HIV Cohort Study. Cohort profile: the Swiss HIV Cohort Study. Int J Epidemiol 2010; 39: 1179-1189.
-
(2010)
the Swiss HIV Cohort Study
, vol.39
, pp. 1179-1189
-
-
-
17
-
-
79953270506
-
-
Food and Drug Administration. Guidance for industry: antiretroviral drugs using plasma HIV RNA measurements - clinical considerations for accelerated and traditional approval. October 2002. Available at (accessed 20 July 2009).
-
Food and Drug Administration. Guidance for industry: antiretroviral drugs using plasma HIV RNA measurements - clinical considerations for accelerated and traditional approval. October 2002. Available at (accessed 20 July 2009).
-
-
-
-
18
-
-
77950356923
-
Triple class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years
-
Pursuing Later Treatment Options II (PLATO II) Project Team for the Collaboration of HIV Epidemiologic Research Europe (COHERE)
-
Pursuing Later Treatment Options II (PLATO II) Project Team for the Collaboration of HIV Epidemiologic Research Europe (COHERE). Triple class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years. Arch Intern Med 2010; 170: 410-419.
-
(2010)
Arch Intern Med
, vol.170
, pp. 410-419
-
-
-
19
-
-
34548655652
-
Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment
-
Arch Intern Med
-
von Wyl V, Yerly S, Boni J et al. Emergence of HIV-1 drug resistance in previously untreated patients initiating combination antiretroviral treatment: a comparison of different regimen types. Arch Intern Med 2007; 167: 1782-1790.
-
(2007)
a comparison of different regimen types
, vol.167
, pp. 1782-1790
-
-
von Wyl, V.1
Yerly, S.2
Boni, J.3
-
20
-
-
59849127268
-
Update of the drug resistance mutations in HIV-1
-
Johnson VA, Brun-Vezinet F, Clotet B et al. Update of the drug resistance mutations in HIV-1. Top HIV Med 2008; 16: 138-145.
-
(2008)
Top HIV Med
, vol.16
, pp. 138-145
-
-
Johnson, V.A.1
Brun-Vezinet, F.2
Clotet, B.3
-
21
-
-
0033570279
-
Analysis of binary outcomes in longitudinal studies using weighted estimating equations and discrete-time survival methods
-
Stat Med
-
Carlin JB, Wolfe R, Coffey C, Patton GC. Analysis of binary outcomes in longitudinal studies using weighted estimating equations and discrete-time survival methods: prevalence and incidence of smoking in an adolescent cohort. Stat Med 1999; 18: 2655-2679.
-
(1999)
prevalence and incidence of smoking in an adolescent cohort
, vol.18
, pp. 2655-2679
-
-
Carlin, J.B.1
Wolfe, R.2
Coffey, C.3
Patton, G.C.4
-
22
-
-
34547529771
-
Prior data for non-normal priors
-
Greenland S. Prior data for non-normal priors. Stat Med 2007a; 26: 3578-3590.
-
(2007)
Stat Med
, vol.26
, pp. 3578-3590
-
-
Greenland, S.1
-
23
-
-
34447343362
-
Bayesian perspectives for epidemiological research. II. Regression analysis
-
Greenland S. Bayesian perspectives for epidemiological research. II. Regression analysis. Int J Epidemiol 2007b; 36: 195-202.
-
(2007)
Int J Epidemiol
, vol.36
, pp. 195-202
-
-
Greenland, S.1
-
25
-
-
79953284295
-
-
Schmidt UE. Closure of the tipranavir POTENT trial. 9 June 2008. Available at (accessed 10 September 2009).
-
Schmidt UE. Closure of the tipranavir POTENT trial. 9 June 2008. Available at (accessed 10 September 2009).
-
-
-
-
26
-
-
33645315892
-
Bayesian perspectives for epidemiological research
-
Int J Epidemiol
-
Greenland S. Bayesian perspectives for epidemiological research: I. Foundations and basic methods. Int J Epidemiol 2006; 35: 765-775.
-
(2006)
I. Foundations and basic methods
, vol.35
, pp. 765-775
-
-
Greenland, S.1
-
27
-
-
18444418548
-
Why clinicians are natural bayesians
-
Gill CJ, Sabin L, Schmid CH. Why clinicians are natural bayesians. BMJ 2005; 330: 1080-1083.
-
(2005)
BMJ
, vol.330
, pp. 1080-1083
-
-
Gill, C.J.1
Sabin, L.2
Schmid, C.H.3
-
28
-
-
39449122181
-
Bayesians in clinical trials
-
Stat Med
-
Moye LA. Bayesians in clinical trials: asleep at the switch. Stat Med 2008; 27: 469-482.
-
(2008)
asleep at the switch
, vol.27
, pp. 469-482
-
-
Moye, L.A.1
-
30
-
-
0034159815
-
Problems due to small samples and sparse data in conditional logistic regression analysis
-
Greenland S, Schwartzbaum JA, Finkle WD. Problems due to small samples and sparse data in conditional logistic regression analysis. Am J Epidemiol 2000; 151: 531-539.
-
(2000)
Am J Epidemiol
, vol.151
, pp. 531-539
-
-
Greenland, S.1
Schwartzbaum, J.A.2
Finkle, W.D.3
-
31
-
-
42149135585
-
Virological response to darunavir/ritonavir-based regimens in antiretroviral-experienced patients (PREDIZISTA study)
-
Pellegrin I, Wittkop L, Joubert LM et al. Virological response to darunavir/ritonavir-based regimens in antiretroviral-experienced patients (PREDIZISTA study). Antivir Ther 2008; 13: 271-279.
-
(2008)
Antivir Ther
, vol.13
, pp. 271-279
-
-
Pellegrin, I.1
Wittkop, L.2
Joubert, L.M.3
-
32
-
-
55849125465
-
Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients
-
Molto J, Santos JR, Perez-Alvarez N et al. Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients. Antimicrob Agents Chemother 2008; 52: 3928-3932.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 3928-3932
-
-
Molto, J.1
Santos, J.R.2
Perez-Alvarez, N.3
-
33
-
-
22144431885
-
Contradicted and initially stronger effects in highly cited clinical research
-
Ioannidis JP. Contradicted and initially stronger effects in highly cited clinical research. JAMA 2005; 294: 218-228.
-
(2005)
JAMA
, vol.294
, pp. 218-228
-
-
Ioannidis, J.P.1
|