The traditional japanese medicine rikkunshito promotes gastric emptying via the antagonistic action of the 5-HT 3 receptor pathway in rats

Evidence-based Complementary and Alternative Medicine

Volumn 2011, Issue , 2011, Pages

  Tominaga, K ^a   Kido, T ^b   Ochi, M ^a   Sadakane, C ^b   Mase, A ^b   Okazaki, H ^a   Yamagami, H ^a   Tanigawa, T ^a   Watanabe, K ^a   Watanabe, T ^a   Fujiwara, Y ^a   Oshitani, N ^a   Arakawa, T ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TSUMURA AND CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 CHLOROPHENYL)BIGUANIDE; ATROPINE; DOPAMINE; GASTROINTESTINAL AGENT; HESPERIDIN; ONDANSETRON; RIKKUNSHITO; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH EMPTYING; TRADITIONAL MEDICINE;

EID: 79953279150     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nep173     Document Type: Article

References (30)

1. Tatsuta M., Iishi H., Effect of treatment with Liu-Jun-Zi-Tang (TJ-43) on gastric emptying and gastrointestinal symptoms in dyspeptic patients Alimentary Pharmacology and Therapeutics 1993 7 4 459 462 (Pubitemid 23267023)
2. Yagi M., Homma S., Kubota M., Iinuma Y., Kanada S., Kinoshita Y., Ohtaki M., Yamazaki S., Murata H., The herbal medicine Rikkunshi-to stimulates and coordinates the gastric myoelectric activity in post-operative dyspeptic children after gastrointestinal surgery Pediatric Surgery International 2004 19 12 760 765 (Pubitemid 38387456)
3. Kawahara H., Kubota A., Hasegawa T., Okuyama H., Ueno T., Ida S., Fukuzawa M., Effects of rikkunshito on the clinical symptoms and esophageal acid exposure in children with symptomatic gastroesophageal reflux Pediatric Surgery International 2007 23 10 1001 1005 (Pubitemid 47437358)
4. Kido T., Nakai Y., Kase Y., Sakakibara I., Nomura M., Takeda S., Aburada M., Effects of Rikkunshi-to, a traditional Japanese medicine, on the delay of gastric emptying induced by NG-nitro-L-arginine Journal of Pharmacological Sciences 2005 98 2 161 167 (Pubitemid 40943722)
5. Ochi M., Tominaga K., Tanaka F., Tanigawa T., Shiba M., Watanabe T., Fujiwara Y., Oshitani N., Higuchi K., Arakawa T., Effect of chronic stress on gastric emptying and plasma ghrelin levels in rats Life Sciences 2008 82 15-16 862 868
6. Iwanaga Y., Miyashita N., Mizutani F., Morikawa K., Kato H., Ito Y., Itoh Z., Stimulatory effect of N-[4-[2-(dimethylamino)-ethoxy]benzyl]-3,4- dimethoxybenzamide hydrochloride (HSR-803) on normal and delayed gastrointestinal propulsion Japanese Journal of Pharmacology 1991 56 3 261 269
7. Vojdani A., Erde J., Regulatory T cells, a potent immunoregulatory target for CAM researchers: modulating tumor immunity, autoimmunity and alloreactive immunity (III) Evidence-Based Complementary and Alternative Medicine 2006 3 3 309 316 (Pubitemid 44310274)
8. Salvioli S., Sikora E., Cooper E. L., Franceschi C., Curcumin in cell death processes: a challenge for CAM of age-related pathologies Evidence-Based Complementary and Alternative Medicine 2007 4 2 181 190
9. Hamasaki N., Ishii E., Tominaga K., Tezuka Y., Nagaoka T., Kadota S., Kuroki T., Yano I., Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro Microbiology and Immunology 2000 44 1 9 15 (Pubitemid 30073693)
10. Tominaga K., Higuchi K., Hamasaki N., Hamaguchi M., Takashima T., Tanigawa T., Watanabe T., Fujiwara Y., Tezuka Y., Nagaoka T., Kadota S., Ishii E., Kobayashi K., Arakawa T., In vivo action of novel alkyl methyl quinolone alkaloids against Helicobacter pylori Journal of Antimicrobial Chemotherapy 2002 50 4 547 552 (Pubitemid 35214795)
11. Oikawa T., Ito G., Hoshino T., Koyama H., Hanawa T., Hangekobokuto (Banxia-houpo-tang), a Kampo medicine that treats functional dyspepsia Evidence-Based Complementary and Alternative Medicine 2009 6 3 375 378
12. Terasawa K., Evidence-based reconstruction of Kampo medicine: part-III-how should Kampo be evaluated? Evidence-Based Complementary and Alternative Medicine 2004 1 219 22
13. Hayakawa T., Arakawa T., Kase Y., Akiyama S., Ishige A., Takeda S., Sasaki H., Uno H., Fukuda T., Higuchi K., Kobayashi K., Liu-Jun-Zi-Tang, a kampo medicine, promotes adaptive relaxation in isolated guinea pig stomachs Drugs under Experimental and Clinical Research 1999 25 5 211 218 (Pubitemid 29497741)
14. Desai K. M., Zembowicz A., Sessa W. C., Vane J. R., Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig Proceedings of the National Academy of Sciences of the United States of America 1991 88 24 11490 11494 (Pubitemid 21916067)
15. Galati E. M., Montforte M. T., Kirjavainen S., Forestieri A. M., Trovato A., Tripodo M. M., Biological effects of hesperidin, a citrus flavonoid. (note I): antiinflammatory and analgesic activity Farmaco 1994 49 11 709 712 (Pubitemid 24356920)
16. Sakata K., Hirose Y., Qiao Z., Tanaka T., Mori H., Inhibition of inducible isoforms of cyclooxygenase and nitric oxide synthase by flavonoid hesperidin in mouse macrophage cell line Cancer Letters 2003 199 139 45 (Pubitemid 37297707)
17. Oldendorf W. H., Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection The American Journal of Physiology 1971 221 6 1629 1639
18. Fukui H., Yamamoto M., Ando T., Sasaki S., Sato S., Increase in serotonin levels in the dog ileum and blood by cisplatin as measured by microdialysis Neuropharmacology 1993 32 10 959 968 (Pubitemid 23316502)
19. Foxx-Orenstein A. E., Kuemmerle J. F., Grider J. R., Distinct 5-HT receptors mediate the peristaltic reflex induced by mucosal stimuli in human and guinea pig intestine Gastroenterology 1996 111 5 1281 1290 (Pubitemid 26362253)
20. Grider J. R., Foxx-Orenstein A. E., Jin J.-G., 5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine Gastroenterology 1998 115 2 370 380 (Pubitemid 28363429)
21. Takeda H., Sadakane C., Hattori T., Katsurada T., Ohkawara T., Nagai K., Asaka M., Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism Gastroenterology 2008 134 7 2004 2013 (Pubitemid 351783256)
22. Barann M., Schmidt K., Gthert M., Urban B. W., Bnisch H., Influence of sodium substitutes on 5-HT-mediated effects at mouse 5-HT3 receptors British Journal of Pharmacology 2004 142 501 8 (Pubitemid 38869864)
23. Price K. L., Millen K. S., Lummis S. C. R., Transducing agonist binding to channel gating involves different interactions in 5-HT3 and GABAC receptors Journal of Biological Chemistry 2007 282 35 25623 25630 (Pubitemid 47372843)
24. Hashimoto K., Kase Y., Murata P., Kido T., Nakai Y., Sakakibara I., Higuchi M., Sasaki H., Okada M., Pharmacological evaluation of Shokyo and Kankyo (1) Biological and Pharmaceutical Bulletin 2002 25 9 1183 1187 (Pubitemid 39655161)
25. Nakai Y., Kido T., Hashimoto K., Kase Y., Sakakibara I., Higuchi M., Sasaki H., Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying Journal of Ethnopharmacology 2003 84 1 51 55 (Pubitemid 36034236)
26. Moayyedi P., Soo S., Deeks J., Delaney B., Innes M., Forman D., Pharmacological interventions for non-ulcer dyspepsia Cochrane Database of Systematic Reviews 2003 1, article no. CD001960
27. Hiyama T., Yoshihara M., Matsuo K., Kusunoki H., Kamada T., Ito M., Tanaka S., Chayama K., Haruma K., Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials Journal of Gastroenterology and Hepatology 2007 22 10 1566 1570 (Pubitemid 47383326)
28. Holtmann G., Talley N. J., Liebregts T., Adam B., Parow C., A placebo-controlled trial of itopride in functional dyspepsia New England Journal of Medicine 2006 354 8 832 840 (Pubitemid 43290921)
29. Curran M. P., Robinson D. M., Mosapride: in gastrointestinal disorders Drugs 2008 68 7 981 991 (Pubitemid 351652925)
30. Suzuki H., Nishizawa T., Hibi T., Therapeutic strategies for functional dyspepsia and the introduction of the Rome III classification Journal of Gastroenterology 2006 41 6 513 523 (Pubitemid 44138192)