Liu-Jun-Zi-Tang, a kampo medicine, promotes adaptive relaxation in isolated guinea pig stomachs

Drugs under Experimental and Clinical Research

Volumn 25, Issue 5, 1999, Pages 211-218

  Hayakawa, T ^a   Arakawa, T ^b   Kase, Y ^a   Akiyama, S ^a   Ishige, A ^a   Takeda, S ^a   Sasaki, H ^a   Uno, H ^b   Fukuda, T ^b   Higuchi, K ^b   Kobayashi, K ^b  

^a TSUMURA AND CO   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CISAPRIDE; GUANETHIDINE; HERBACEOUS AGENT; KAMPO; LIU JUN ZI TANG; METOCLOPRAMIDE; N(G) NITROARGININE; PROKINETIC AGENT; TJ 43; TRIMEBUTINE; UNCLASSIFIED DRUG;

ADAPTATION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DYSPEPSIA; GUINEA PIG; MALE; NONHUMAN; SMOOTH MUSCLE RELAXATION; STOMACH DISTENSION; STOMACH MUSCLE; STOMACH PRESSURE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ARGININE; CISAPRIDE; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; GASTROINTESTINAL AGENTS; GASTROINTESTINAL MOTILITY; GUINEA PIGS; HUMANS; MALE; METOCLOPRAMIDE; MUSCLE RELAXATION; NITROARGININE; STOMACH; TRIMEBUTINE;

EID: 0032746367     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Goso Y., Ogata Y., Ishihara K., Hotta K. Effects of traditional herbal medicine on gastric mucin against ethanol-induced gastric injury in rats. Comp. Biochem. Physiol. C. Pharmacol. Toxicol. Endocrinol., 113, 17, 1996.
2. Tatsuta M., Iishi H. Effect of treatment with Liu-Jun-Zi-Tang (TJ-43) on gastric emptying and gastrointestinal symptoms in dyspeptic patients. Aliment. Pharmacol. Ther., 7, 459, 1993.
3. Urbain J.C., Siegel J.A., Debie N.C., Pauwels S.P. Effect of cisapride on gastric emptying in dyspeptic patients. Dig. Dis. Sci., 33, 779, 1988.
4. Jian R., Ducrot F., Ruskone A., et al. Symptomatic, radionuclide and therapeutic assessment of chronic idiopathic dyspepsia. Dig. Dis. Sci., 34, 657, 1989.
5. Waldron B., Cullen P.T., Kumar R., et al. Evidence for hypomotility in non-ulcer dyspepsia: a prospective multifactorial study. Gut, 32, 246, 1991.
6. Troncon L.E.A., Bennett R.J.M., Ahluwalia N.K., Thompson D.G. Abnormal intragastric distribution of food during gastric emptying in functional dyspepsia patients. Gut, 35, 327, 1994.
7. Troncon L.E.A., Thompson D.G., Ahluwala N.K., Barlow J., Heggie L. Relations between upper abdominal symptoms and gastric distension abnormalities in dysmotility like functional dyspepsia and after vagotomy. Gut, 37, 17, 1995.
8. Desai K.M., Sessa W.C., Vane J.R. Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid. Nature, 351, 477, 1991.
9. Desai K.M., Zembowicz A., Sessa W.C., Vane J.R. Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig. Proc. Natl. Acad. Sci., 88, 11490, 1991.
10. Uno H., Arakawa T., Fukuda T., Higuchi K., Kobayashi K. Involvement of capsaicin-sensitive sensory nerves in gastric adaptive relaxation in isolated guinea pig stomachs. Digestion, 58, 232, 1997.
11. Inoue M., Sekiguchi T., Harasawa S., Miwa T., Miyoshi A. Dyspepsia and dyspepsia subgroups in Japan: Symptom profiles and experience with cisapride. Scand. J. Gastroenterol., 195 (Suppl), 36, 1993.
12. Fermin M., Mercedes C., Fernando A., Juan R.M. The origin of symptoms on the brain-gut axis in functional dyspepsia. Gastroenterology, 101, 999, 1991.
13. Lemann M. Abnormal perception of viscera pain in response to gastric distention in chronic idiopathic dyspepsia. Dig. Dis. Sci., 36, 1249, 1991.
14. Merz H. Gastric balloon distention as a diagnostic test for non ulcer dyspepsia. Gastroenterology, 28, 763, 1993.
15. Hausken T., Berstad A. Effect of glyceryl trinitrate on antral motility and symptoms in patients with functional dyspepsia. Scand. J. Gastroenterol., 29, 23, 1993.