In vitro anticancer activity and evaluation of DNA duplex binding affinity of phenyl-substituted indoloquinolines

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 8, 2011, Pages 2380-2383

  Riechert Krause, Fanny ^a   Eick, Andrea ^a   Grünert, Renate ^a   Bednarski, Patrick J ^a   Weisz, Klaus ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Cytotoxicity; DNA binding; Indoloquinoline; Spectroscopy

Indexed keywords

ALKYL GROUP; DOUBLE STRANDED DNA; ETHIDIUM; INDOLOQUINOLINE DERIVATIVE; PHENYL GROUP; SODIUM ION;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BASE PAIRING; BIOLOGICAL ACTIVITY; BLADDER CANCER; BREAST CANCER; CANCER CELL CULTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA DENATURATION; DRUG DNA BINDING; DRUG STRUCTURE; DRUG TARGETING; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERCALATION COMPLEX; LUNG CANCER; PANCREAS CANCER;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CIRCULAR DICHROISM; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; INTERCALATING AGENTS; NEOPLASMS; QUINOLINES; SPECTROMETRY, FLUORESCENCE; TRANSITION TEMPERATURE;

EID: 79953270892     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.02.088     Document Type: Article

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