Blend uniformity end-point determination using near-infrared spectroscopy and multivariate calibration

Journal of Pharmaceutical and Biomedical Analysis

Volumn 55, Issue 3, 2011, Pages 429-434

  Sulub, Yusuf ^a   Konigsberger, Michele ^a   Cheney, James ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b CELGENE CORPORATION   (United States)

Author keywords

Blend uniformity; Near infrared; Off line calibration; Partial least squares; Pharmaceutical

Indexed keywords

CROSPOVIDONE; LACTOSE; MICROCRYSTALLINE CELLULOSE;

ARTICLE; CALIBRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KERNEL METHOD; MICROELECTROMECHANICAL SYSTEM; MULTIVARIATE ANALYSIS; NEAR INFRARED SPECTROSCOPY; PRIORITY JOURNAL;

CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG COMPOUNDING; ENDPOINT DETERMINATION; EXCIPIENTS; LEAST-SQUARES ANALYSIS; MODELS, THEORETICAL; MULTIVARIATE ANALYSIS; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SPECTROSCOPY, NEAR-INFRARED; TABLETS;

EID: 79953253138     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.02.017     Document Type: Article

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