Real-time on-line blend uniformity monitoring using near-infrared reflectance spectrometry: A noninvasive off-line calibration approach

Journal of Pharmaceutical and Biomedical Analysis

Volumn 49, Issue 1, 2009, Pages 48-54

  Sulub, Yusuf ^a   Wabuyele, Busolo ^a   Gargiulo, Paul ^a   Pazdan, James ^a   Cheney, James ^a   Berry, Joseph ^b   Gupta, Abhay ^c   Shah, Rakhi ^c   Wu, Huiquan ^c   Khan, Mansoor ^c  

^a NOVARTIS PHARMA AG   (Switzerland)

^b QRxPharma Inc   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Blend uniformity; Near infrared; Off line calibration; Partial least squares; Pharmaceutical

Indexed keywords

CROSPOVIDONE; LACTOSE; MICROCRYSTALLINE CELLULOSE;

ARTICLE; CALIBRATION; DRUG FORMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROELECTROMECHANICAL SYSTEM; NEAR INFRARED REFLECTANCE SPECTROSCOPY; NON INVASIVE PROCEDURE; PARTIAL LEAST SQUARES REGRESSION; PRIORITY JOURNAL;

CALIBRATION; DOSAGE FORMS; DRUG COMPOUNDING; EXCIPIENTS; LEAST-SQUARES ANALYSIS; PHARMACEUTICAL PREPARATIONS; SPECTROSCOPY, NEAR-INFRARED; TIME FACTORS;

EID: 58249125677     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.10.001     Document Type: Article

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