Transactivation potencies of the Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor α by perfluoroalkyl carboxylates and sulfonates: Estimation of PFOA induction equivalency factors

Environmental Science and Technology

Volumn 45, Issue 7, 2011, Pages 3123-3130

  Ishibashi, Hiroshi ^a   Kim, Eun Young ^b   Iwata, Hisato ^a  

^a EHIME UNIVERSITY   (Japan)

^b Kyung Hee University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITIVE ACTION; BAIKAL SEAL; BIOLOGICAL EFFECTS; CARBON-CHAIN LENGTH; COMPLEX MIXTURE; CORRELATION ANALYSIS; CYTOCHROME P450; DOSE-DEPENDENT MANNER; EFFECTIVE CONCENTRATION; HEPATIC CONCENTRATIONS; HEPATIC EXPRESSION; IN-VITRO; NEGATIVE CORRELATION; PERFLUOROCHEMICALS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; POSITIVE CORRELATIONS; REPORTER GENE ASSAYS; STRUCTURE ACTIVITY RELATIONSHIPS; TRANSACTIVATION; TRANSCRIPTIONAL ACTIVITY; WET WEIGHT;

CARBOXYLATION; CONCENTRATION (PROCESS); CYTOLOGY; GENES;

WATER ANALYSIS;

CYTOCHROME P450 4A; PERFLUORO COMPOUND; PERFLUOROALKYL CARBOXYLATE; PERFLUOROALKYL SULFONATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; UNCLASSIFIED DRUG;

BIOLOGICAL ANALYSIS; CORRELATION; CYTOCHROME; DOSE-RESPONSE RELATIONSHIP; FRESHWATER ECOSYSTEM; ORGANOFLUORINE; PINNIPED; WILD POPULATION;

ARTICLE; CORRELATION ANALYSIS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; NONHUMAN; PROTEIN EXPRESSION; PUSA SIBIRICA; REPORTER GENE; SEAL; STRUCTURE ACTIVITY RELATION; TOXICITY; TRANSACTIVATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROCARBONS; GENE EXPRESSION; OCTANOIC ACIDS; PPAR ALPHA; RNA, MESSENGER; SEALS, EARLESS; TRANSCRIPTIONAL ACTIVATION; WATER POLLUTANTS, CHEMICAL;

PHOCA SIBIRICA;

EID: 79953248849     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es103748s     Document Type: Article

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